• Journal of the Korean Society for information Management
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• v.37 no.2
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• pp.285-310
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• 2020

This paper analyzed SCOAP3 journals, which have been evaluated as successful open access models, to understand the characteristics of scholarly communication among domestic researchers in the field of high energy physics (HEP). As research methods, a quantitative analysis using statistics and a network analysis of authors' affiliated institutions and academic journals were conducted to understand collaboration and research activities of domestic researchers in the HEP field. The results of the study revealed that, among the 10 SCOAP3 journals in which Korean researchers participated, the proportion of articles in which Korean authors participated was 8.0% of the total. The proportion of papers with more than 1,000 co-authors per paper was 28.7% of the total. The results of this analysis proved that Korean researchers were actively collaborating in the HEP global network. From the results of the network analysis to understand the cooperative relationship centered on the affiliated organization, the cooperative network could be divided into three clusters: a cluster centered on S universities, a cluster centered on K research institutes that provided researchers a cooperative infrastructure with CERN, and a cluster centered on I research institute. Through the network analysis for research institutes and journals, it was found that JHEP, PRD, and PLB among academic journals were highly participating journals, and universities and researchers were also participating in the writing of open access papers. The results of this study can be used as a basic resource for understanding researchers and building a research information environment in libraries.

• Toxicological Research
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• v.31 no.1
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• pp.11-16
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• 2015

Our body's immune system has defense mechanisms against pathogens such as viruses and bacteria. Immune responses are primarily initiated by the activation of toll-like receptors (TLRs). In particular, TLR4 is well-characterized and is known to be activated by gram-negative bacteria and tissue damage signals. TLR4 requires myeloid differentiation factor 2 (MD2) as a co-receptor to recognize its ligand, lipopolysaccharides (LPS), which is an extracellular membrane component of gram-negative bacteria. Gambogic acid is a xanthonoid isolated from brownish or orange resin extracted from Garcinia hanburyi. Its primary effect is tumor suppression. Since inflammatory responses are related to the development of cancer, we hypothesized that gambogic acid may regulate TLR4 activation. Our results demonstrated that gambogic acid decreased the expression of pro-inflammatory cytokines ($TNF-{\alpha}$, IL-6, IL-12, and $IL-1{\beta}$) in both mRNA and protein levels in bone marrow-derived primary macrophages after stimulation with LPS. Gambogic acid did not inhibit the activation of Interferon regulatory factor 3 (IRF3) induced by TBK1 overexpression in a luciferase reporter gene assay using IFN-${\beta}$-PRD III-I-luc. An in vitro kinase assay using recombinant TBK1 revealed that gambogic acid did not directly inhibit TBK1 kinase activity, and instead suppressed the binding of LPS to MD2, as determined by an in vitro binding assay and confocal microscopy analysis. Together, our results demonstrate that gambogic acid disrupts LPS interaction with the TLR4/MD2 complex, the novel mechanism by which it suppresses TLR4 activation.

• Journal of the Korean Data and Information Science Society
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• v.27 no.3
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• pp.639-651
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• 2016

"Law on price announcement for real estate" which was revised as of Jan. 19, 2016 (will be enforced as of Sep. 1, 2016) decided the introduction of 'Price announcement system for non-residential property' for the first time. However, its introduction seems to be delayed based on two reasons. Firstly the methodology for introduction of non-property system is not definitized, despite many problems were brought up for current tax base of non-residential property. In addition, changes in tax base will place a burden on the government. In this regard, this study analyzed actual transaction price data throughout one year to analyze equity of taxation for non-residential property and to find major factor which affects on the tax base, in relation with the change of current public announcement system to actual transaction based system. And this is the first study that applied actual transaction price to non-residential property.

• Steel and Composite Structures
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• v.22 no.1
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• pp.63-77
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• 2016

Top-down construction is a construction technique in which pit excavation and structure construction are conducted simultaneously. Reducing construction time and minimizing noise and vibration which affect neighboring structures, the technique is widely employed in constructing downtown structures. While H-steel columns have been commonly used as core columns, concrete filled steel tube (CFT) columns are at the center of attention because the latter have less axial directionality and greater cross-sectional efficiency than the former. When compared with circular CFT columns, square CFT columns are more easily connected to the floor structure and the area of percussion rotary drilling (PRD) is smaller. For this reason, square CFT columns are used as core columns of concrete encased and filled square (CET) columns in underground floors. However, studies on the structural behavior and concrete stress transfer of CET columns have not been conducted. Since concrete is cast according to construction sequence, checking the stress of concrete inside the core columns and the stress of covering concrete is essential. This paper presents the results of structural tests and analyses conducted to evaluate the usability and safety of CET columns in top-down construction where CFT columns are used as core columns. Parameters in the tests are loading condition, concrete strength and covering depth. The compressive load capacity and failure behavior of specimens are evaluated. In addition, 2 cases of field application of CET columns in underground floors are analyzed.

• Journal of Biomedical Engineering Research
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• v.17 no.1
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• pp.121-128
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• 1996

This paper presents the ECG data compression method referred the adaptive fractal interpolation algorithm. In the previous piecewise fractal interpolation(PFI) algorithm, the size of range is fixed So, the reconstruction error of the PFI algorithm is nonuniformly distributed in the part of the original ECG signal. In order to improve this problem, the adaptive fractal interpolation(AEI) algorithm uses the variable range. If the predetermined tolerance was not satisfied, the range would be subdivided into two equal size blocks. large ranges are used for encoding the smooth waveform to yield high compression efficiency, and the smaller ranges are U for encoding rapidly varying parts of the signal to preserve the signal quality. The suggested algorithm was evaluated using MIT/BIH arrhythmia database. The AEI algorithm was found to yield a relatively low reconstruction error for a given compression ratio than the PFI algorithm. In applications where a PRD of about 7.13% was acceptable, the ASI algorithm yielded compression ratio as high as 10.51, without any entropy coding of the parameters of the fractal code.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.45 no.4
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• pp.42-50
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• 2008

The real-time bio-signal monitoring system based on the ZigBee and SIP/RTP has proposed and implemented for telemedicine but that has some problems at the stabilities to transmit bio-signal from the sensors to the other sides. In this paper, we designed and implemented a real-time bio-signal monitoring system that is focused on the reliability and efficiency for transmitting bio-signal at real-time. We designed the system to have enhanced architecture and performance in the ubiquitous sensor network, SIP/RTP real-time transmission and management of the database. The Bluetooth network is combined with ZigBee network to distribute traffic of the ECG and the other bio-signal. The modified and multiplied RTP session is used to ensure real-time transmission of ECG, other bio-signals and speech information on the internet. The modified ECG compression method based on DWLT and MSVQ is used to reduce data rate for storing ECG to the database. Finally we implemented a system that has improved performance for transmitting bio-signal from the sensors to the monitoring console and database. This implemented system makes possible to make various applications to serve U-health care services.

• Particle and aerosol research
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• v.11 no.3
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• pp.63-75
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• 2015

Atmospheric environment in Korea is influenced by outside, especially China. The concentrations of air pollutants in China have showed decreasing trends since 2000. However, these concentration levels in China are still higher than other developed countries. The Chinese Government has tried several measures to control the air pollution. In this study, the details of the amendments and smog reduction strategies in China, especially for Beijing are reviewed and the strategies for Korean side to promote cooperation in Northeast Asia are suggested and discussed. The Chinese State Council amended the Environmental Protection Provisions and Clean Air Act and announced The Action Plan for Air Pollution Control (2013-2017), focusing on three key regions, Beijing-Tianjin-Hebei area (Jing-Jin-Ji), Yangtze River Delta (YRD) and Pearl River Delta (PRD). These policy actions and plan are mainly for the reducing coal usage and emissions from vehicles. It is suggested that, Korea should actively promote multi-national cooperation in the region to take an initiative role in environmental areas.