• Animal Bioscience
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• 제35권4호
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• pp.544-555
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• 2022

Objective: Spermatozoa are produced within the seminiferous tubules after sexual maturity. The expression levels of mRNAs and lncRNAs in testicular tissues are different at each stage of testicular development and are closely related to formation of the extracellular matrix (ECM) and spermatogenesis. Therefore, we set out to study the expression of lncRNAs and mRNAs during the different developmental stages of the goat testis. Methods: We constructed 12 RNA libraries using testicular tissues from goats aged 3, 6, and 12 months, and studied the functions of mRNAs and lncRNAs using the gene ontogeny (GO) and Kyoto encyclopedia of genes and genomes (KEGG) databases. Relationships between differentially expressed genes (DEGs) were analyzed by lncRNA-mRNA co-expression network and protein-protein interaction network (PPI). Finally, the protein expression levels of matrix metalloproteinase 2 (MMP2), insulin-like growth factor 2 (IGF2), and insulin-like growth factor-binding protein 6 (IGFBP6) were detected by western blotting. Results: We found 23, 8, and 135 differentially expressed lncRNAs and 161, 12, and 665 differentially expressed mRNAs that were identified between 3 vs 6, 6 vs 12, and 3 vs 12 months, respectively. GO, KEGG, and PPI analyses showed that the differential genes were mainly related to the ECM. Moreover, MMP2 was a hub gene and co-expressed with the lncRNA TCONS-0002139 and TCONS-00093342. The results of quantitative reverse-transcription polymerase chain reaction verification were consistent with those of RNA-seq sequencing. The expression trends of MMP2, IGF2, and IGFBP6 protein were the same as that of mRNA, which all decreased with age. IGF2 and MMP2 were significantly different in the 3 vs 6-month-old group (p<0.05). Conclusion: These results improve our understanding of the molecular mechanisms involved in sexual maturation of the goat testis.

• 한국엔터테인먼트산업학회논문지
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• 제13권2호
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• pp.57-65
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• 2019

본 연구는 산림 자원의 다양한 효과 중에서 정서적인 안정과 같은 심리적 요인에 대한 과학적 접근이다. 본 연구를 진행하기 위하여 산림 치유공간을 다양한 공간으로 설정하여 피실험자들을 대상으로 실험을 진행하였다. 본 실험에 참여한 피실험자들은 20대 대학생들로 평균 나이가 22±1.25세였다. 피실험자들은 지정된 각기 다른 산림치유공간에서 주관적 서열평가를 통해 감성 단어들에 대한 평가를 실시하였다. 또한 이들의 인식하는 감성에 대한 생체반응을 측정하여 실제로 인지하고 있는 감성적 상태를 확인하였다. 본 연구에 적용된 생체신호반응 실험으로는 심박이 나타내는 BMP, SDNN, VLF, LF, HF, Amplitude 및 PPI를 활용하였다. 본 실험의 결과는 통계적 처리를 위해여 Friedman 검증과 Wilcoxon 검증을 적용하여 측정하였다. 본 연구에서는 주관적 감성어휘별에 대해서는 '좋은', '맑은' 및 '불편한' 단어가 산림치유공간의 지점별로 통계적 유의성을 확인하였다. 또한 산림 치유공간 각 지점에서의 정량적 생체신호 측정결과는 SDNN, HF 및 Amplitude가 통계적으로 유의하게 나타났다. 본 연구는 산림치유공간의 다양한 지역적 공간에서 인간이 인지하는 감성적 차원을 측정하였다. 산림 공간에 있어서도 공간적 입지가 인간의 감성적 차원을 유도하는 분위기가 다르다는 것을 확인한 것이다. 본 연구의 결과를 기반으로 산림치유공간 및 산림 자원의 활용 분야에 대한 적용방향과 전략적 활용방안을 제시할 수 있다. 이는 감성 기반의 산린 치유에 대한 공간적 시설 및 물리적 요건들을 통해 시설을 이용하는 이용객들에게 가이드를 제공할 뿐만 아니라 개인 맞춤형 감성 공간 디자인적 측면으로도 활용이 가능하다.

• Bulletin of the Korean Chemical Society
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• 제34권9호
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• pp.2583-2588
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• 2013

A new type of solid and gel-state ionics based on siloxane pyridinium iodides was synthesized and used as electrolytes in dye-sensitized solar cells. The resulting electrolytes were characterized by $^1H$ NMR spectroscopy, TGA and diffusion coefficient. The synthesized siloxane pyridinium iodide electrolytes have characteristics of different chain length of siloxane moieties. The ion conductivities were given 2.7-3.2 S/cm. Among the three SiDPIs based electrolytes, DSSC employing the SiDPI2 gives an open circuit voltage of 0.704 V, a short-circuit current of 15.85 $mA/cm^2$ and conversion efficiency of 6.8% under light intensity of 100 $mW/cm^2$. In addition, the performance of the DSSCs showed relatively reasonable compared with the propylpyridinium iodide (PPI) electrolyte.

• 수산경영론집
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• 제27권1호
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• pp.67-90
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• 1996

As an important factor of capitalism economics, price of commodities represents a certain country's economic index. For having correct price policy, there should be an appropriate mechanism to make and use systematic statistical data on price. Price statistics are made by indexes and price indexes are categorized into producer price index(PPI) and consumer price index(CPI). The Bank of Korea is publishing producer price index every year, but the producer price index contains some problems. These include as follows : (a) the impractical selection of fisheries products sample (b) uncorrect measure of aquatic products weights (c) investigating sample places. This study try to substitute producer price index of aquatic products and change construction of fisheries producer price index with experimental research on representative fisheries, weight of each fisheries, and suitability of investigating sample places. It is possible to improve practical fisheries producer price index with the results of this research. The findings are as follow. (a) It will be helpful for the government to make the fisheries price policy. (b) It can be used to understand trends of accurate price and price increase of aquatic products, and it's possible to compare with it other industrial indexes including the mining, agricultural, and manufacturing industry and understand relative price movement. (c) When free sales systems of fisheries products as expected, it will be helpful to analyze price movement of producing fisheries cooperatives, producing fisheries market and consuming fisheries market, analysis of market, and formation and consideration of budget. (d) It can be an important index to determine labor wage.

• 재무관리논총
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• 제14권1호
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• pp.97-117
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• 2008

본 연구의 목적은 AR(1)-GARCH(1, 1)모형을 이용하여 우리나라의 거시경제변수의 변동성으로부터 주식시장의 변동성으로 전이효과(spillover)가 존재하는지를 규명하는데 있다. 본 연구는 자본시장이 개방되기 시작한 1992년 1월부터 2007년 6월까지 186개월치의 KOSPI 지수 및 주요산업지수와 거시경제변수인 정부의 통화정책을 반영하는 콜금리, 미달러환율, 인플레이션의 대용치인 생산자물가지수 자료에 근거하여 거시경제변수의 주식시장에 대한 변동성전이효과를 AR(1)-GARCH(1, 1)모형을 이용하여 분석하였다. 분석결과에 따르면 콜금리의 KOSPI 지수수익률에 대해 변동성전이효과는 통계적으로 비유의적으로 나타나 변동성전이효과가 없는 것으로 나타났으며 환율은 KOSPI에 대해 양(+)의 변동성전이효과가 존재함을 보였다. 이는 미달러환율의 기대치 않은 변동성이 주식시장의 변동성에 양(+)으로 충격을 준다는 것을 의미한다. 또한 인플레이션의 대용치인 생산자물가지수(PPI)는 주식시장에 대해 변동성전이효과가 1% 유의수준에서 통계적으로 유의하여 강한 변동성전이효과가 존재하는 것으로 나타났다. 이러한 결과는 이자율을 나타내는 콜금리를 제외하고 Cumhur, Arslan and Meziyet(2005)의 연구와 동일한 결과를 보였다.

• 동의신경정신과학회지
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• 제18권3호
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• pp.331-340
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• 2007

The etiology of chronic headache is not yet fully explained, the treatment of this symptom is not simple. We show the effect of Qigong therapeutics applied on chronic headache patient, in order to establish a primary data for further studies of new treatments. We treated 2 times a weeks for 3 weeks. The acupoints, (太陽穴)(Ex-HN5), (老龍穴), (大趾甲下穴), and (百會穴)(GV20) were stimulated for 10 seconds by Qigong-Acupuncture, and after that Qigong therapy was performed for 30 minutes The effects were analyzed using VAS scores, PPI(Present Pain Intensity), HI(Headache Index) and HDI(The Henry Ford Headache Disability Inventory). We concluded that Qigong therapeutics applied on chronic headache patient showed effects of relieving pain, improving general activities and changing the mood. Further researches are needed to evaluate the distinct functional mechanism of Qigong therapeutics, hut this study is meaningful in the sense that it will act as a fundamental study to build on.

• Asian Pacific Journal of Cancer Prevention
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• 제16권6호
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• pp.2561-2567
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• 2015

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer death worldwide. Our study aimed to reveal molecular mechanisms. Microarray data of GSE15471 (including 39 matching pairs of pancreatic tumor tissues and patient-matched normal tissues) was downloaded from Gene Expression Omnibus (GEO) database. We identified differentially expressed genes (DEGs) in PDAC tissues compared with normal tissues by limma package in R language. Then GO and KEGG pathway enrichment analyses were conducted with online DAVID. In addition, principal component analysis was performed and a protein-protein interaction network was constructed to study relationships between the DEGs through database STRING. A total of 532 DEGs were identified in the 38 PDAC tissues compared with 33 normal tissues. The results of principal component analysis of the top 20 DEGs could differentiate the PDAC tissues from normal tissues directly. In the PPI network, 8 of the 20 DEGs were all key genes of the collagen family. Additionally, FN1 (fibronectin 1) was also a hub node in the network. The genes of the collagen family as well as FN1 were significantly enriched in complement and coagulation cascades, ECM-receptor interaction and focal adhesion pathways. Our results suggest that genes of collagen family and FN1 may play an important role in PDAC progression. Meanwhile, these DEGs and enriched pathways, such as complement and coagulation cascades, ECM-receptor interaction and focal adhesion may be important molecular mechanisms involved in the development and progression of PDAC.

• 유통과학연구
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• 제15권12호
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• pp.41-51
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• 2017

Purpose - This study proposes the impact of the US and Korean economic policy uncertainty on macroeconomy, and its effect on Korea. The economic policy uncertainty index of the US and Korea is used to represent the economic policy uncertainty on Korean economy. Research design, data, and methodology - In this paper, we collect the eight variables to find out the interrelationship among the US and Korean economic policy uncertainty index of the US and macroeconomic indicators during 1990 to 2016, and use Vector Error Correction Model. Result - The distribution industry stock index in Korea is influenced by the economic policy uncertainty index of the US rather than of Korea. All variables are related negatively to the economic policy uncertainty index of the US and Korea from Vector Error Correction Model. This study shows that the economic policy uncertainty index of the US and Korea has the dynamic relationships on the Korean economy. Conclusions - A higher economic policy uncertainty shows a greater economy recession of a country. Finally, the economic policy uncertainty of the Korea has an intensive impact on Korea economy. Particularly, the economic policy uncertainty of the US has a strong impact on distribution industry stock market in Korea.

• The Journal of Asian Finance, Economics and Business
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• 제5권2호
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• pp.43-51
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• 2018

We study the impact of economic policy uncertainty (EPU) of Asian four countries such as Korea, Japan, Hong Kong, and China on housing market returns in Korea. Also, we document the relationship between the EPU index of those four countries and the housing market including macroeconomic indicators in Korea. The EPU index of those four countries has significantly a negative effect on the housing purchase price index, housing lease price index in Korea. The EPU index in Korea and Japan has significantly a negative effect on the CPI. The EPU index in only Japan has significantly a negative effect on the PPI. The EPU index in Hong Kong and Korea has significantly a negative effect but the EPU index in China significantly has a positive effect on the stock price index in construction industry. The EPU index in only Korea has significantly a negative effect the stock price index in banking industry. This study shows the EPU index of the Korea has the negative relationships on the housing market economy rather than other countries by VECM. And this study has an important evidence of the spillover of several macroeconomic indicators in Korea for the EPU index of the Asian four countries.

• 한국정보통신학회논문지
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• 제4권5호
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• pp.971-976
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• 2000

The main objective of this paper is to present the rain cell size distribution observed during squall line episodes in the Sudano-Sahelian region. The used data were collected during the EPSAT Program [Etude des Precipitation par SATellite (Satellites Study of Precipitation)] which has been developed since 1958, on an experimental area located near Niamey, Niger (2 10′32"E, 13 28′38"N). The data were obtained with a C-band radar and a network composed of approximately 100 raingages over a 10,000 $\textrm{km}^2$. In this work a culling of the squall line episodes was made for the 1992 rainy season. After radar data calibration using the raingage network a number of PPI (Plan Position Indicator) images were generated. Each image was then treated in order to obtain a series of radar reflectivity (Z) maps. To describe the cell distribution, a contouring program was used to analyze the areas with rain rate greater than or equal to the contour threshold (R$\geq$$\tau$). 24700 contours were generated, where each iso-pleth belongs to a predefined threshold. Computing each cell surface and relating its area to an equi-circle (a circle having the same area as the cell), a statistical analysis was made. The results show that the number of rain cells having a given size is an inverse exponential function of the equivalent radius. The average and median equivalent radii ate 1.4 and 0.69 In respectively. Implications of these results for the precipitation estimation using threshold methods are discussed.