• 정보처리학회논문지D
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• 제15D권6호
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• pp.741-754
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• 2008

지속적으로 확장되는 데이터 스트림에 대한 데이터 마이닝 수행과정에서는 메모리 사용량을 가용한 범위 내로 제한하는 것이 중요한 요소이다. 본 논문에서는 데이터 스트림 환경에서 한정된 메모리 공간을 이용하여 빈발 항목집합을 탐색하는데 효과적인 프라임 패턴 트리(Prime pattern tree: PPT)구조를 제안한다. 프라임 패턴 트리는 기존의 전위 트리 구조와 비교하여 항목집합들을 하나의 노드로 관리함으로써 트리의 크기를 크게 줄일 수 있는 장점이 있다. 또한, 전지 임계값 $S_{\delta}$에 따라 노드를 병합하거나 분리하여 동적으로 트리의 크기와 결과 집합의 정확도를 마이닝 수행 중에 조절 할 수 있다. $S_{\delta}$값이 크면 한 노드에서 관리되는 항목집합의 수가 증가하게 되고, 출현 빈도수를 추정해야 하기 때문에, $S_{\delta}$값이 작을수록 결과집합의 정확도가 높다. 이처럼 PPT에는 트리의 크기와 정확도의 trade-off 가 존재한다. PPT의 이러한 특성에 기반하여, 데이터 스트림에서 갑자기 데이터 집합에 변화가 생겨 빈발항목이 될 가능성이 높은 항목들이 많이 출현하는 경우에도 마이닝을 지속적으로 수행할 수 있도록 지원한다. 본 논문에서는 프라임 패턴 트리를 이전 연구에서 제안한 데이터 스트림에서 최근 빈발 항목 탐색 방법인 estDec 방법에 적용하여 한정된 작은 양의 메모리 공간을 이용하여 온라인 데이터 스트림에서 빈발항목을 탐색하는 방법을 제시한다. 또한, 가용 메모리 범위에서 최적의 메모리를 사용하여 최적의 마이닝 결과를 얻을 수 있도록 하는 메모리 사용량에 대한 적응적 방법을 제시한다. 끝으로, 여러 실험을 통한 효율성 검증을 통해 제안된 방법의 여러 특성을 확인한다.

• Journal of Ginseng Research
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• 제39권3호
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• pp.189-198
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• 2015

Background: Antiallergic effect of 20(S)-protopanaxatriol (PPT), an intestinal metabolite of ginseng saponins, was investigated in guinea pig lung mast cells and mouse bone marrow-derived mast cells activated by a specific antigen/antibody reaction. Methods: Increasing concentrations of PPT were pretreated 5 min prior to antigen stimulation, and various inflammatory mediator releases and their relevant cellular signaling events were measured in those cells. Results: PPT dose-dependently reduced the release of histamine and leukotrienes in both types of mast cells. Especially, in activated bone marrow-derived mast cells, PPT inhibited the expression of Syk protein, cytokine mRNA, cyclooxygenase-1/2, and phospholipase $A_2$ ($PLA_2$), as well as the activities of various protein kinase C isoforms, mitogen-activated protein kinases, $PLA_2$, and transcription factors (nuclear factor-${\kappa}B$ and activator protein-1). Conclusion: PPT reduces the release of inflammatory mediators via inhibiting multiple cellular signaling pathways comprising the $Ca^{2+}$ influx, protein kinase C, and $PLA_2$, which are propagated by Syk activation upon allergic stimulation of mast cells.

• Journal of Ginseng Research
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• 제37권3호
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• pp.300-307
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• 2013

20S-dihydroprotopanaxatriol (2H-PPT) is a derivative of protopanaxatrol from ginseng. Unlike other components from Panax ginseng, the pharmacological activity of this compound has not been fully elucidated. In this study, we investigated the modulatory activity of 2H-PPT on the cellular responses of monocytes and macrophages to understand its immunoregulatory actions. 2H-PPT strongly upregulated the release of radicals in sodium nitroprusside-treated RAW264.7 cells and the surface levels of costimulatory molecule CD86. More importantly, this compound remarkably suppressed nitric oxide production, morphological changes, phagocytic uptake, cell-cell aggregation, and cell-matrix adhesion in RAW264.7 and U937 cells in the presence or absence of lipopolysaccharide, anti-CD43 antibody, fibronectin, and phorbal 12-myristate 13-acetate. Therefore, our results suggest that 2H-PPT can be applied as a novel functional immunoregulator of macrophages and monocytes.

• 한국측량학회:학술대회논문집
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• 한국측량학회 2006년도 춘계학술발표회 논문집
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• pp.541-546
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• 2006

Recently, slope failures are happen to natural disastrous when they occur in mountainous areas adjoining highways in Korea. The accidents associated with slope failures have increased due to rapid urbanization of mountainous areas. Therefore, Regular maintenance is essential for all slope and needs maintenance of road safety as well as road function. The purpose of this paper is to recommend a standard of a $N_{10}^{\sim}$ value of Distribution of a potential failure layer using PPT(Portable penetration test).

• 대한전기학회논문지:전기기기및에너지변환시스템부문B
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• 제55권4호
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• pp.216-223
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• 2006

In this paper, a methodology for the efficiency improvement of the photovoltaic system without adding some elements or increasing the cost comparing with the conventional system is discussed. It is suggested the optimal photovoltaic module configuration through its performance analysis, and also the suitable maximum power point tracking (MPPT) voltage considered the system cost and the efficiency of the converter. The high efficiency photovoltaic system by using the parallel power transfer (PPT) based MPPT converter is proposed and analyzed theoretically comparing with the conventional Buck type MPPT converter. Finally, it is designed and implemented the proposed photovoltaic system for supplying DC 48V by using the PPT based MPPT converter. And the effect of the efficiency improvement and the usefulness of the proposed system is proved through some preliminary simulation and experiment results.

• 한국양식학회지
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• 제14권1호
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• pp.17-27
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• 2001

Effects of temperature (10, 12, 14, 16, 18 and 2$0^{\circ}C$) and salinity (22.0, 24.5, 27.0, 29.5, 32.0 and 34.5 ppt) were studied on incubation period, hatching success, survival and growth of alevin and juvenile seabass, L. japonicus. Embryonic development was accelerated with increasing temperature but it was not influenced by salinity. Hatching success was the highest at 14$^{\circ}C$ and 34.5 ppt. Higher temperature also accelerated the development of mouth opening, absorption of yolk and oil globules, and alevin growth. Survival of the 5-day old Juvenile was accelerated in the following order : 14<16<18<20<12$^{\circ}C$. Rearing experiment of the juvenile for 30-day indicated the faster growth at 13, 20 and 27 ppt than at 34 ppt.

• Applied Microscopy
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• 제39권1호
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• pp.17-25
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• 2009

본 연구에서는 에스트로겐 수용체 알파 효능제인 propyl pyrazole triol (PPT)을 수컷 생쥐에 투여하였을 때 부속 생식샘의 조직학적 변화가 유발되는지를 조사하였다. 광학현미경으로 조사하기 위해 수컷 생식기관을 고정, 탈수, 포매, 절편 과정을 거쳐 프레파라트를 완성하였다. PPT에 의해 복부쪽 전립샘, 정낭, 포피샘의 각 무게는 실험기간에 따라 감소되었다. 투여군의 경우, 복부쪽 전립샘의 샘 조직 내강은 위축되었다. 전립샘 상피조직의 형태가 단층 원주상피에서 중층 입방 상피 혹은 편평상피로 변화되었다. 투여군 전립샘과 정낭의 상피조직 아래에 있는 결합조직은 증가되었다. 특히, 투여군 정낭의 내강이 대조군에 비해 위축되었다. 포피샘의 투여군 8주에서 상피세포 높이가 감소되었다. 수컷 내에서 에스트로겐 수용체 효능제의 이런 영향을 파악함으로서 생식기관 내 에스트로겐의 생리학적 기능을 이해하는데에 도움을 줄 것으로 사료된다.

• Applied Microscopy
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• 제46권4호
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• pp.193-200
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• 2016

Male reproductive organs are strongly affected by estrogen signaling mediated via the estrogen receptor. In this study, propyl pyrazole triol (PPT), an estrogen receptor alpha agonist, was subcutaneously injected in adult male mice every 2 days for a total duration of 8, 16, or 24 days. Histological changes in the reproductive organs, including the testes, efferent ductules, and epididymides, were observed. The weight of the reproductive organs decreased in the PPT group. In addition, the diameter of the seminiferous tubules decreased in the PPT group compared with the control group. The epithelial cell height decreased in the initial segment of the epididymis, whereas the luminal diameter increased in the efferent ductules of the PPT group. PPT induced irregular morphology of stereocilia in the luminal region of the initial segment. Therefore, PPT treatment at high concentrations had inhibitory effects in the reproductive organs of adult male mice. These findings suggest that short-term treatment with estrogen receptor agonist causes histological changes in the testes, efferent ductules, and epididymis, which are similar to those caused by estrogen receptor antagonist treatment. Therefore, the estrogen receptor may have functional roles in male reproductive organs, implying that treatment with an estrogen receptor agonist can affect male fertility.

• 국제물리치료학회지
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• 제10권4호
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• pp.1914-1920
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• 2019

Background: Mobilization and cranio-cervical flexion exercise has been reported in reducing pain from cervical part and improving its motor function; also, has been represented that alleviate of neck pain and recover of neck muscles improve the normal gait performance. However, few studies have identified the effects of mobilization and exercise on pain and gait parameters with preceding issues. Objective: To examine the effects or changes of pressure pain threshold (PPT) and gait parameters in patients with chronic neck pain. Design: Cross-Sectional Clinical Trials Methods: Twenty patients with the history of neck pain (>3 months) performed the cervical mobilization and cranio-cervical flexion exercise. Gait parameters were assessed with wireless device and collected data were transmitted to the personal computer via Bluetooth. The PPT was measured posteroanterior direction at the prone position and the mean of subsequent three PPT measurements was used for the final analysis. Results: Both cervical central posteroanterior mobilization (CCPAM) (p<.000) and sling-based cranio-cervical flexion exercise (SBCCFE) (p<.000) group showed a significant increase in the PPT and the gait parameters, cadence (p<.023), was significantly increased in the CCPAM group, however slightly increased in the SBCCFE group. The comparison between the CCPAM and the SBCCFE groups after treatment did not show significant differences for the score on the PPT and gait parameters. Conclusions: This study suggests that CCPAM and SBCCFE increase PPT, cadence, and gait speed.

• 대한한의학회지
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• 제43권4호
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• pp.1-7
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• 2022

Objectives: This study aimed to determine whether comparing the pressure pain threshold (PPT) with an algometer before and after treatment for functional dyspepsia is of diagnostic value and investigate a possible correlation between PPT measured using an algometer and symptom improvement before and after treatment. Methods: A total of 99 patients with functional dyspepsia symptoms admitted to the OO Korean Medical Hospital from April 14, 2020 to January 21, 2021 were investigated. On the 1st and 14th days of hospitalization, the pressure of the first pain complaint at acupuncture points Juque (巨厥, CV14), Shangwan (上脘, CV13), Zhongwan (中脘, CV12), Xiawan (下脘, CV10), Guanuan (關元, CV4), Tianshu (天樞, ST25), and Daju (大巨, ST27) was measured using the algometer, and the visual analog scale (VAS) scores for patient's symptoms were evaluated. The algometer PPT and patient-symptom VAS scores were compared by repeated measures corresponding to the sample t-test to analyze the changes after treatment. A correlation analysis was performed to identify the correlation between patient-symptom VAS scores and algometer PPT. Results: The PPT measured using the algometer significantly increased after treatment in the 99 patients. The patient-symptom VAS score decreased significantly in most cases as treatment progressed. Analysis of the correlation between algometer PPT and patient-symptom VAS scores revealed some notable negative correlations. Conclusion: The algometer can help to set the diagnostic and treatment baselines for patients with functional dyspepsia.