• Korean Journal of Fisheries and Aquatic Sciences
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• v.34 no.1
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• pp.57-69
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• 2001

The chemical, elemental and biochemical components of the suspended particulate matter (SPM) were investigated in order to quantify particulate organic matter (POM) and assess diet quality for suspension feeders in the southern coastal bay systems of Korea where the marine farming of the suspension feeders are most active, The intense field observation program was carried out seasonally in the three coastal bay systems of Chinhae, Gosung and Kangjin bays, The SPM was characterized as collective properties of organic carbon (POC), nitrogen (PON), phosphorus (PP) and more refined collective properties of protein (PPr), carbohydrate (PCHO) and chlorophyll a (Chl a) compound. Although the three coastal bays are regarded as phytoplankton based ecosystem, the SPM is not composed entirely with phytoplankton cells. Due to the shallow water depth, resuspension of bottom sediment contributes significantly to some of the regions. Therefore, concentration of SPM in the surface water did not co-vary with Chl a or PPr, PCHO. In general, temporal variation of POC, PON and Chl a contents in seawater were closely associated with phytoplankton biomass in the three coastal bays, However, PPr and PCHO contents in seawater were higher in Chinhae bay than in Gosung and Kangjin bays and Chl a PPr-N ratio was higher in Chinhae bay than in Kosung and Kangjin bays, since Chinhae bay is more eutrophicated than other bays. Average C : N ratios from regressions of POC and PON of SPM were 6.6, 6.6 and 5.0 in Chinhae, Gosung and Kangjin bays, respectively. SPM in Chinhae and Gosung bays appears to be made of largely phytoplankton cells and SPM in Kangjin bay appears to be contributed from the bacterial biomass due to the shallow water depth. N : P ratios from regressions of PON and PP of SPM were 10.8 and 14.7 in spring, and 18.2 and 24.6 in Chinhae and Gosung bays, respectively. With respect to the hypothetical Redfield molecule, phytoplankton appears to be limited by the lack of N and f in spring and summer, respectively, in the two bays, In Kangjin bay, N : P ratios from regressions of PON and PP of SPM were varied from 6.3 to 12.8 throughout the year. The low N : P ratio with resepct to the hypothetical Redfield molecule, phytoplankton growth appears to be limited by the lack of N-nutrients.

• Communications for Statistical Applications and Methods
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• v.7 no.3
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• pp.633-641
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• 2000

In this paper, we propose a method to identify multiple outliers in regression analysis with only assumption of smoothness on the regression function. Our method uses single-linkage clustering algorithm and Projection Pursuit Regression (PPR). It was compared with existing methods using several simulated and real examples and turned out to be very useful in regression problem with the regression function which is far from linear.

• Proceedings of the Korea Information Processing Society Conference
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• 2009.11a
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• pp.775-776
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• 2009

공간데이터를 관리하는 공간 index structure는 대부분 순차처리를 위한 구조를 가지고 있다. 많은 응용분야에서 방대한 양의 공간 데이터는 보조기억장치(예: disk)에 저장이 되어 사용이 되고 공간 index structure의 operation은 I/O에 대한 의존도가 크므로, I/O operation의 병렬처리는 공간 index structure의 질의반응시간을 현저하게 줄일 수 있다. 본 논문에서는 PPR-tree라는 병렬형 공간 index structure를 제안한다.

• Journal of the Society of Naval Architects of Korea
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• v.43 no.3 s.147
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• pp.392-398
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• 2006

A prototype of MES(Manufacturing Execution System) applied to panel assembly shop is implemented by using PDA(Personal Digital Assistant) and wireless database web server. The system is developed based on the Dot Net framework. The prototype can exchange the manufacturing execution data between production managers in the control room and workers in the factory through wireless internet communication. Manufacturing model of the panel shop is designed by using IDEF0 and UML method to understand the characteristics of the information and the data entities from the PPR-S view. Several issues in the shop were revealed from the manufacturing model analysis. The most typical problem was the lack of information sharing between the managing workers and the assembly workers. The problem prevents the workers and labors from sharing the process information and continuous workpiece flow In interactive way. To increase the information and data flow, a wireless internet based system is implemented and PDAs are linked together to exchange the process planning data and in-process data between the workers. It is anticipated that PDA and the implemented system can enable the process control at each process stages to obtain the well-organized operation.

• The Korean Journal of Physiology and Pharmacology
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• v.7 no.6
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• pp.295-301
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• 2003

Striatum plays a crucial role in the movement control and habitual learning. It receives an information from wide area of cerebral cortex as well as an extensive serotonergic (5-hydroxytryptamine, 5-HT) input from raphe nuclei. In the present study, the effects of 5-HT to modulate synaptic transmission were studied in the rat corticostriatal brain slice using in vitro extracellular recording technique. Synaptic responses were evoked by stimulation of cortical glutamatergic inputs on the corpus callosum and recorded in the dorsal striatum. 5-HT reversibly inhibited coticostriatal glutamatergic synaptic transmission in a dose-dependent fashion (5, 10, 50, and $10{\mu}M$), maximally reducing in the corticostriatal population spike (PS) amplitude to $40.1{\pm}5.0$% at a concentration of $50{\mu}M$ 5-HT. PSs mediated by non-NMDA glutamate receptors, which were isolated by bath application of the NMDA receptor antagonist, d,l-2-amino-5-phospohonovaleric acid (AP-V), were decreased by application of $50{\mu}M$ 5-HT. However, PSs mediated by NMDA receptors, that were activated by application of zero $Mg^{2+}$ aCSF, were not significantly affected by $50{\mu}M$ 5-HT. To test whether the corticostriatal synaptic inhibitions by 5-HT might involve a change in the probability of neurotransmitter release from presynaptic nerve terminals, we measured the paired-pulse ratio (PPR) evoked by 2 identical pulses (50 ms interpulse interval), and found that PPR was increased ($33.4{\pm}5.2$%) by 5-HT, reflecting decreased neurotransmitter releasing probability. These results suggest that 5-HT may decrease neurotransmitter release probability of glutamatergic corticostriatal synapse and may be able to selectively decrease non-NMDA glutamate receptor-mediated synaptic transmission.

• Journal of Veterinary Science
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• v.25 no.2
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• pp.21.1-21.15
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• 2024

Background: Peste des petits ruminants (PPR) is a contagious and fatal disease of sheep and goats. PPR virus (PPRV) infection induces endoplasmic reticulum (ER) stress-mediated unfolded protein response (UPR). The activation of UPR signaling pathways and their impact on apoptosis and virus replication remains controversial. Objectives: To investigate the role of PPRV-induced ER stress and the IRE1-XBP1 and IRE1-JNK pathways and their impact on apoptosis and virus replication. Methods: The cell viability and virus replication were assessed by 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assay, immunofluorescence assay, and Western blot. The expression of ER stress biomarker GRP78, IRE1, and its downstream molecules, PPRV-N protein, and apoptosis-related proteins was detected by Western blot and quantitative reverse transcription-polymerase chain reaction, respectively. 4-Phenylbutyric acid (4-PBA) and STF-083010 were respectively used to inhibit ER stress and IRE1 signaling pathway. Results: The expression of GRP78, IRE1α, p-IRE1α, XBP1s, JNK, p-JNK, caspase-3, caspase-9, Bax and PPRV-N were significantly up-regulated in PPRV-infected cells, the expression of Bcl-2 was significantly down-regulated. Due to 4-PBA treatment, the expression of GRP78, p-IRE1α, XBP1s, p-JNK, caspase-3, caspase-9, Bax, and PPRV-N were significantly downregulated, the expression of Bcl-2 was significantly up-regulated. Moreover, in PPRV-infected cells, the expression of p-IRE1α, p-JNK, Bax, and PPRV-N was significantly decreased, and the expression of Bcl-2 was increased in the presence of STF-083010. Conclusions: PPRV infection induces ER stress and IRE1 activation, resulting in apoptosis and enhancement of virus replication through IRE1-XBP1s and IRE1-JNK pathways.

• Communications for Statistical Applications and Methods
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• v.3 no.3
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• pp.113-123
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• 1996

Data-dependent (adaptive) choice of asymptotically efficient score functions for rank estimators and M-estimators of regression parameters in a linear regression model with left-truncated and right-censored data are developed herein. The locally adaptive smoothing techniques of Muller and Wang (1990) and Uzunogullari and Wang (1992) provide good estimates of the hazard function h and its derivative h' from left-truncated and right-censored data. However, since we need to estimate h'/h for the asymptotically optimal choice of score functions, the naive estimator, which is just a ratio of estimated h' and h, turns out to have a few drawbacks. An altermative method to overcome these shortcomings and also to speed up the algorithms is developed. In particular, we use a subroutine of the PPR (Projection Pursuit Regression) method coded by Friedman and Stuetzle (1981) to find the nonparametric derivative of log(h) for the problem of estimating h'/h.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.16 no.3
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• pp.44-49
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• 2007

Recent manufacturing system requires development on new production technology to enable prompt manufacturing of diverse products. Most of the researchers have been working on micro-factory. Especially, focus on manufacturing of micro parts. Present manufacturing system consumes excessive resources in the form of energy and space to manufacture the micro parts. In this study, the micro lens module assembly system was modeled, analyzed with MST(Micro System Technology) Application Module and simulated through UML Language (Unified Modeling Language) with object-oriented logical model analysis method. Digital model of micro-factory was modeled, to execute the new paradigm of digitalization on products, resources and processes of micro-factory.

• Journal of Institute of Control, Robotics and Systems
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• v.14 no.4
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• pp.369-375
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• 2008

The kinematics and control problem of a visual alignment system is investigated, which plays a crucial role in the fabrication process of flat panel displays. The first solution is the inverse kinematics of a 4PPR parallel alignment mechanism. It determines the driving distance of each joint to compensate the misalignment between mask and panel. Second, an efficient vision algorithm for fast alignment mark recognition is suggested, where by extracting essential feature points to represent the geometry of a mark, the geometric template matching enables much faster object recognition comparing with the general template matching. Finally, the overall visual alignment process including the kinematic solution, vision algorithm, and joint control is implemented and experimental results are given.

• Communications for Statistical Applications and Methods
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• v.9 no.1
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• pp.213-220
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• 2002

Anthropometric survey is important as a basis for human engineering fields. According to our experiences, there are difficulties in obtaining the measurements of some body parts because respondents are reluctant to expose. In order to overcome these difficulties, we propose a method for estimating such hard-to-measure measurements by using easy-to-measure measurements those are closely related to them. Multiple Regression Model, Feedforward Neural Network(FNN) Model and Projection Pursuit Regression(PPR) Model will be used as analytical tools for this purpose. The method we propose will be illustrated with real data from the 1992 Korea national anthropometric survey.