• Title/Summary/Keyword: POLYMER

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Preparation and Release Behavior of Atorvastatin Calcuim - Encapsulated Polyoxalate Microspheres (아토르바스타틴 칼슘을 함유한 폴리옥살레이트 미립구의 제조 및 방출거동)

  • Lee, Cheon Jung;Kim, Su Young;Lee, Hyun Gu;Yang, Jaewon;Park, Jin Young;Cha, Se Rom;Lim, Dong-Kwon;Lee, Dongwon;Khang, Gilson
    • Polymer(Korea)
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    • v.38 no.5
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    • pp.656-663
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    • 2014
  • Atorvastatin calcium-loaded polyoxalate (POX) microspheres were prepared by an emulsion solvent-evaporation/ extraction method of oil-in-oil-in-water ($O_1/O_2/W$) for sustained release. We investigated the release behavior according to initial drug ratio, molecular weight ($M_w$) and concentration of POX and concentration of emulsifier. The microsphere was characterized on the surface, the cross-section morphology and the behavior of atorvastatin calcium release for 10 days by scanning electron microscopy (SEM) and high performance liquid chromatography (HPLC). The analysis of crystallization was analyzed to use X-ray diffraction (XRD), differential scanning calorimeter (DSC) and Fourier transform infrared (FTIR). These results showed that the release behaviors can be controlled by preparation conditions.

Effects of Attachment and Proliferation of Retinal Pigment Epithelial Cells on Silk/PLGA Film (실크/PLGA 필름에서 실크 함량이 망막색소 상피세포의 부착 및 증식 거동에 미치는 영향)

  • Jo, Eun-Hye;Kim, Soo-Jin;Cho, Su-Jin;Lee, Ga-Young;Kim, On-You;Lee, Eun-Yong;Cho, Won-Hyung;Lee, Dong-Won;Khang, Gil-Son
    • Polymer(Korea)
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    • v.35 no.4
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    • pp.289-295
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    • 2011
  • Biomaterials for retinal tissue engineering must demonstrate several critical features for potential utility, including mechanical integrity, biocompatibility, and slow biodegradation. Silk film biomaterials were designed and characterized to meet these functional requirements. We prepared natural/synthetic hybrid silk/PLGA films using 0, 10, 20, 40, and 80 wt% of silk by a solvent evaporation method. MIT assay was used to confirm the number of cells attached on film at 1, 2, and 3 days, respectively. The morphology of cellular adhesion on films was also confirmed by scanning electron microscope (SEM). RT-PCR was conducted to confrrm mRNA expression of retinal pigment epithelitun (RPE) using RPE65 as a RPEs marker and the expression of cytokeratin were determined by immunofluorescence staining. We confirmed that the silk/PLGA film of 20~40 wt% silk was superior for the adhesion and proliferation of RPEs.

Study on the relief design for the fault current of polymer arrester (폴리머 피뢰기의 고장전류에 대한 방압 설계기술에 관한 연구)

  • Kim, In-Sung;Park, Hoy-Yul;Cho, Han-Goo
    • Proceedings of the KIEE Conference
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    • 1999.07d
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    • pp.1717-1719
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    • 1999
  • The chief advantage of polymer arrester. from design of pressure relief, anti-contamination, electrical failure was reduced by outdoor polymer housing. In the first for development of pressure relief design for polymer arrester, fault current and surge were studied through experiments of electrical. Designed the FRP inner tube and unit modules for pressure relief housing. Tested the performance of unit modules for pressure relief of polymer arrester, and the result was successful. The pressure relief of polymer arrester depend on design pattern of diamond shape and ellipse. Study on the pressure relief of FRP inner tube for outdoor polymer arrester. Designed and manufactured FRP inner tube of polymer arrester. Tested the fault current of polymer arrester per 10 kA, 10 cycle.

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Condensation of Nano-Size Polymer Aggregates by Spin Drying

  • Ishikawa, Atsushi;Kawai, Akira
    • Journal of Adhesion and Interface
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    • v.6 no.1
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    • pp.7-10
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    • 2005
  • Condensation control of nano-particles has become important in order to fabricate minute condensed structures. In this study, we focus our attention on condensation mechanism of polymer aggregates in a resist film. The polymer aggregate is structural component of a resist material which is used in lithography process. The condensation nature of polymer aggregates in the resist film surface is observed by using atomic force microscope (AFM). By using the AFM, the condensation of polymer aggregates can be observed clearly. The condensation of polymer aggregate strongly affects to precise fabrication of resist pattern below 100nm size. The interaction force among polymer aggregates can be analyzed based on Derjaguin approximation. We also discuss about condensation nature of polymer aggregates in the resist film surface with the help of micro sphere model.

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Fully Rod-like Aromatic Polyimides: Structure, Properties, and Chemical Modifications

  • Moonhor Ree;Shin, Tae-Joo;Lee, Seung-Woo
    • Macromolecular Research
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    • v.9 no.1
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    • pp.1-19
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    • 2001
  • Poly(p-phenylene pyromellitimide) and poly(4,4'-biphenylene pyromellitimide) are representatives of fully rod-like polyimides. Their structure and properties in thin films are reviewed. The polymers exhibit some excellent properties such as high molecular packing coefficient, high mechanical modulus, and low thermal expansion coefficient, and low interfacial stress, so that they are very attractive to both industry and academia. However, these polymers are very brittle and thus practically useless. Some chemical modifications to improve such drawback with a little sacrifice of the high modulus are described: i) incorporation of short side groups into the polymer backbone and ii) insertion of proper linkages into the polymer backbone.

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The Relaxation of Nonlinear Optical Properties in a Poled Polymer (극화된 고분자에서 비선형 광학특성의 완화)

  • Jung, Chi-Sup
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.23 no.6
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    • pp.491-496
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    • 2010
  • The relaxation behavior of aligned electric dipoles in a mixed polymer of P2ANS with P(VDF-TrFE) is studied with optical second harmonic generation (SHG). In this work, a macroscopic noncentrosymmetry of the spin coated film was achieved by an electrical poling. The relaxation of induced polar order of nonlinear optic(NLO) chromophores after poling leads to an insufficient long-term stability of NLO properties. In this work, we develop a new technique to suppress such kind of dipole relaxation in a poled polymer. We found that the poled dipoles in a NLO polymer were effectively immobilized by the internal electric field created by a thermally annealed ferroelectric polymer. The long-term stability in a mixed system of NLO polymer/ferroelectric polymer was successively accomplished by a series of thermal treatments applied to the mixed polymer system at a temperature of $140^{\circ}C$ for at least 1hour after poling.

Drying Shrinkage of Polymer-Modified Mortar Using redispersible Polymer Powder (재유화형 분말수지를 혼입한 폴리머 시멘트 모르타르의 건조수축)

  • Joo, Myung-Ki;Lee, Youn-Su;Yeon, Kyu-Seok;Jo, Kyu-Woo
    • Proceedings of the Korean Society of Agricultural Engineers Conference
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    • 2002.10a
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    • pp.165-168
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    • 2002
  • The effects of polymer-cement ratio, antifoamer agent content and shrinkage-reducing agent content on the drying shrinkage of polymer-modified mortars using redispersible polymer powder are examined. As a result, irrespective of the antifoamer content, the drying shrinkage of the polymer-modified mortars using redispersible polymer powder tend to decrease with increasing polymer-cement ratio and shrinkage-reducing agent content. Such a drying shrinkage development is due to the effect of reducing water from incorporation of EVA redispersible polymer powder and antifoamer agent.

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Structural Evaluation of Glass-fiber Reinforced 3-Layer Polymer Composite Pipe (GFRP 보강 폴리머 모르터 3중복합관의 구조적 특성)

  • Yeon, Kyu-Seok;Kwon, Yoon-Hwan;Ryu, Keun-Woo;Jin, Nan-Ji
    • Proceedings of the Korean Society of Agricultural Engineers Conference
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    • 2001.10a
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    • pp.147-151
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    • 2001
  • This study was performed to evaluate the internal and external factors affecting external strength of the 3-layer polymer composite pipes made of polymer mortar and fiber-glass reinforced plastic. Twenty four sandwich type 3-layer polymer composite pipes were made of polymer mortar and fiber-glass reinforced plastic by centrifugal method. The objective of this study was to evaluate the effects the of polymer mortar thickness for and core fiber-glass contents per unit area on external strength of 3-layer polymer composite pipes. For the more economical and practical design of 3-layer polymer composite pipe, further study should be done for the various polymer mortar, fiber-glass and different ratio of the inside/outside FRP thickness.

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Characterization and Experimental Verification of Solid Polymer Electrolyte for Conductive Polymer Actuator Operated in Air (공기 중에서 동작하는 전도성 고분자 액추에이터용 고체전해질의 특성 분석 밑 실험적 검증)

  • An, Ho-Jeong;Lee, Seung-Gi;Park, Jeong-Ho
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.51 no.3
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    • pp.125-133
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    • 2002
  • In order to fabricate stable conductive polymer actuators which can be operated in air, conductivity and solidity of polymer electrolyte materials have been studied. It was found that Nafion+LiCl is appropriate material to be used for conductive polymer actuator. Using the Nafion+LiCl solid polymer electrolyte, single layer PPy actuators have been fabricated and their deflection was measured. Double layer PPy actuators make up for shortcoming of single layer PPy actuator and displacement and frequency response can be improved by fabrication of double layer PPy actuator. This kind of all-solid-polymer actuator can be used for practical applications.

Design of Single Ion Conductive Solid Polymer Electrolytes Utilizing the Characteristics of the Boron Atom

  • Matsumi, Noriyoshi;Ohno, Hiroyuki
    • Proceedings of the Polymer Society of Korea Conference
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    • 2006.10a
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    • pp.275-275
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    • 2006
  • A series of organoboron polymer electrolytes were prepared and their ion conductive characteristics was investigated in detail. Alkylborane type polymer electrolytes prepared by hydroboration polymerization exhibited improve lithium transference number due to efficient anion trapping of alkylborane unit. A lithium borate type polymer/salt hybrid was also successfully prepared by dehydrocoupling polymerization of lithium mesitylhydrorate. Ionic conductivity of single ion conductive polymer/salt hybrid was further improved in the case of comb like polymer/boron stabilized imido anion hybrid prepared via polymer reaction of poly(organoboron halide) with hexylamine and PEO monomethylether and subsequent neutralization with lithium hydride.

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