• 한방안이비인후피부과학회지
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• 제23권1호
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• pp.59-74
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• 2010

Objectives : Atopic dermatitis(AD) is a chronic recurrent skin disease which usually developed in infancy or childhood. AD often repeat improvement and relapse. The cause of AD is so indefinite that many methods of therapies(moisturizer, steroid ointment, antihistamine, immunomodulator, immunosuppressant, herbal medicine, alternative medicine, etc.) are tried. Recently, a lot of studies were made. But there is no report about the effect of Samulsopungeum(SM) and Prednisolone(PN) on AD. So, author aimed to investigate the effects of SM and PN on AD of NC/Nga mice. Methods : Thirty two mice(8 Balb/c mice and 24 NC.Nga mice) were divided into four groups; Balb/c mice was normal group. NC/Nga mice were divide into three group : control, PN, SM group. AD was induced in the control, PN, SM group by spreading DNCB. Then normal saline, PN and SM were orally administered three times in a week for 8 weeks to the control, PN, SM group, respectively. We observed changes of clinical skin severity score, serum IgE, IgG1, IFN-$\gamma$, IL-2, IL-4, IL-5, IL-10, IL-13, and so on. We used one-way ANOVA test statistically(p<0.01). Results : The clinical skin severity scores of PN group and SM group in 8th week were decreased compared to the control group. Serum IgE, IgGl levels of PN group and SM group were significantly decreased compared to the control group. Serum IFN-$\gamma$ in SM group was significantly increased compared to the control group. But, Serum IFN-$\gamma$ in PN group was significantly decreased compared to the control group. Serum IL-10 levels of PN group and SM group were significantly decreased compared to the control group. Serum IL-2, IL-4, IL-5, IL-13 levels of PN group and SM group were significantly decreased compared to the control group. mRNA expression levels of IL-2, IL-4, IL-5, IL-13 in the dorsal skin tissues of PN group and SM group were significantly decreased compared to the control group. According to biopsy reports of the ear and skin tissues showed that the tissue damage of PN group and SM group were highly reduced compared to the control group. Creatinine, BUN, ALT, AST levels of PN group and SM group were normal. Conclusion : According to the above results, it is considered that SM is effective treatment for the AD.

• 한국의학물리학회지:의학물리
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• 제1권1호
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• pp.97-107
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• 1990

본 논문에서는 플라스틱 검출기의 일종인 알릴 다이글리콜 카보네이트 물질 (PN-3) 에서의 하전입자의 검출 방법과 여러장의 흡수체를 통과하여 얻어진 알파 업자의 에너지 (3.17～5.49 MeV) 에 대한 알파입자 궤적의 특성을 논의하였다. 또한 등가흡수선량율을 계산하였고, 일파입자의 도달거리를 특정하기위해 섬광계수기를 사용하였다. PN-3 의 에칭특성과 검출 특성등이 여러가지 변수들로 표현되었다. 즉, 부식당한 입자궤적의 길이가 갖는 각각의 알파입자 에너지에대한 연관성등을 논의하였다. PN-3 플라스틱 선량 검출기에 기록된 알 파업자의 에칭과정에서 매우 흥미있는 결과를 얻었다.

• Applied Microscopy
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• 제47권4호
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• pp.242-250
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• 2017

The purpose of this study was to characterize the prenatal and postnatal development of the mouse parotid salivary gland and tooth, and to investigate the relationship between the developmental timing of the two organs. Development of parotid salivary gland begins on embryonic day 15 (E15), which is the prebud stage; E17 is the initial bud stage; E21 to postnatal day 3 (PN3) is the pseudoglandular stage; PN5 to PN10 is the canalicular stage; and PN21 is the terminal bud stage. At E15, the developing maxillary molar tissue is at the bud stage; at E17, it is at the cap stage; at E21, it is at the early bell stage; PN3 to PN5 comprises the advanced bell stage; at PN10, it is at the crown stage; at PN21, it is at the functional stage. Therefore, unlike the other major salivary glands, the development of mouse parotid salivary gland is completed through a process of prenatal and postnatal morphogenesis and becomes functional at about the same time as the developing tooth. The developmental completion times of the parotid salivary gland and tooth are closely related to the weaning time of animal.

• 한국통신학회논문지
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• 제23권4호
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• pp.967-975
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• 1998

본 논문은 추정회로와 기준 상관수신기를 이용하여 동기 DS/CDMA 시스팀에서 발생하는 다중접속간섭을 제거시키기 위한 시스팀을 제시한다. CDMA 시스템에서, 사용자 신호의 주파수대역을 확산시키기 위한 확산부호로 Simplex 부호 또는 위상 오프셋된 PN부호를 사용한다. Simplex 부호와 PN부호 각각은 유사한 상관특성을 갖는다는 것이 흥미로우며 이러한 부호를 DS/CDMA시스팀에 사용할 수 있다면 수용할 수 있는 사용자의 수를 증가시킬 수 있을 것이다. 본 연구에서는 Simplex 부호와 함께 PN 부호를 확산부호로 사용한 DS/CDMA 시스팀에서 발생하는 다원접속 간섭을 제거할 수 있는 간섭제거모델을 제시한다. AWGN 환경하에서 임의의 사용자에 의해서 발생하는 간섭을 해석하고, 동일 사용자 측면에서 일반 수신기와 성능을 비교한다.

• 한국입자에어로졸학회지
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• 제10권4호
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• pp.163-167
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• 2014

Particle number portable emission measurement system (PN-PEMS) is an instrument for measuring number concentration of automobile exhaust. The principle of some pre-existing commercial PN-PEMS is to charge particles and display the number of particles by measuring current. However, this method has some problems for measuring exhaust. In this study, to solve these issues, we have developed a single particle counting PN-PEMS based condensation particle counter (CPC). The PN-PEMS based CPC does not affect driving conditions and it is convenient for mobile because the instrument is small and light in structure. We evaluated counting efficiency of PN-PEMS based CPC by using electrostatic method (electrometer and Faraday cup).

• 한국임상약학회지
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• 제24권4호
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• pp.240-247
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• 2014

Objective: Undernutrition is common amongst esophageal cancer patients and therefore appropriate nutrition support is critical. Nevertheless, the effectiveness of enteral nutrition (EN) versus parenteral nutrition (PN) is still controversial. The aim of this study was to investigate the effect of EN and PN on the nutritional state and the length of hospital stay for patients who underwent an Ivor-Lewis (IL) esophagectomy. Method: A retrospective clinical analysis was performed that utilized the electronic medical records of patients who underwent IL esophagectomy during a 3-year period between January 2010 and December 2012 at a tertiary teaching hospital located in Seoul, Korea. The EN group and PN group were analyzed by comparing the nutrition supply, postoperative complications, length of hospital stay, and weight variation. Results: After an IL esophagectomy, the complication rate between the EN group and PN group was insignificant and the length of hospital stay was significantly shorter for the PN group compared to the EN group (14 vs. 16 days, respectively; p<0.001). At the time of discharge, those in the PN group lost less weight postoperatively (p=0.003). Conclusion: PN may be considered as safe nutrition support for esophageal cancer patients who underwent an esophagectomy.

• Applied Microscopy
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• 제50권
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• pp.17.1-17.9
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• 2020

Recent advances in fabrication have enabled radial-junction architectures for cost-effective and high-performance optoelectronic devices. Unlike a planar PN junction, a radial-junction geometry maximizes the optical interaction in the three-dimensional (3D) structures, while effectively extracting the generated carriers via the conformal PN junction. In this paper, we report characterizations of radial PN junctions that consist of p-type Si micropillars created by deep reactive-ion etching (DRIE) and an n-type layer formed by phosphorus gas diffusion. We use electron-beam induced current (EBIC) microscopy to access the 3D junction profile from the sidewall of the pillars. Our EBIC images reveal uniform PN junctions conformally constructed on the 3D pillar array. Based on Monte-Carlo simulations and EBIC modeling, we estimate local carrier separation/collection efficiency that reflects the quality of the PN junction. We find the EBIC efficiency of the pillar array increases with the incident electron beam energy, consistent with the EBIC behaviors observed in a high-quality planar PN junction. The magnitude of the EBIC efficiency of our pillar array is about 70% at 10 kV, slightly lower than that of the planar device (≈ 81%). We suggest that this reduction could be attributed to the unpassivated pillar surface and the unintended recombination centers in the pillar cores introduced during the DRIE processes. Our results support that the depth-dependent EBIC approach is ideally suitable for evaluating PN junctions formed on micro/nanostructured semiconductors with various geometry.

• International Journal of Oral Biology
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• 제35권1호
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• pp.13-19
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• 2010

The DNA probes Pn17 and Pn34 were evaluated for their ability to specifically detect clinical strains of P. intermedia and P. nigrescens from a Korean population by dot blot hybridization. These probes were sequenced by extension termination and their specificity was determined by Southern blot analysis. The results revealed that the Pn17 sequence (2,517 bp) partially encodes an RNA polymerase beta subunit (rpoB) and that Pn34 (1,918 bp) partially encodes both rpoB (1-169 nts) and the RNA polymerase beta subunit (rpoB'; 695-1918 nts). These probes hybridized with both HindIII- and PstI-digested genomic DNAs from the strains of P. intermedia and P. nigrescens used in this study. Interestingly, each of the hybrid bands generated from the HindIII-digested genomic DNAs of the two bacterial species could be used to distinguish between them via restriction fragment length polymorphism. These results thus indicate that Pn17 and Pn34 can simultaneously detect P. intermedia and P. nigrescens.

• 방송공학회논문지
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• 제17권5호
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• pp.864-875
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• 2012

본 논문에서는 단일 반송파 MIMO 시스템 기반의 PN 부호열을 이용한 반송파 주파수 오차 추정 방법을 제안한다. 제안하는 방법은 송신되는 각각의 PN 부호열들의 위상을 회전시켜 전송하여, 일부 PN 부호열들이 서로 상쇄되어 버리는 것을 방지한다. 수신한 PN 부호열과 수신기에서 자체 생성한 PN 부호열의 공액곱셈 연산을 통해 변조를 제거한 뒤, 다수의 자기 상관기를 이용한 ML (Maximum Likelihood) 알고리듬을 이용하여 반송파 주파수 오차를 추정한다. 또한 시변채널에서의 정확한 주파수 오차 추정을 위해 채널 정보를 이용한 주파수 오차 추정 구조를 제안하였다. 컴퓨터 모의실험을 통해, 송신 및 수신 안테나가 두 개인 $2{\times}2$ MIMO 시스템에 제안하는 기법을 적용하고 L&R 알고리듬을 이용하여 AWGN (Additive White Gaussian Noise) 환경 및 시변 Rayleigh 채널에서의 MSE (Mean Square Error) 성능을 측정하였다. 그 결과 AWGN 환경 상에서 MIMO 시스템에 적용한 제안된 기법의 MSE 성능이 SISO 시스템에서의 성능과 거의 동일함을 보였다. 또한 시변 Rayleigh 채널에서 제안된 채널 정보를 이용한 추정 기법의 MSE 성능이 기존 방법 및 SISO 시스템에 비해 높음을 보였다.

• 대한화학회지
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• 제40권7호
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• pp.509-514
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• 1996

3차원 금속착체 포접화합물 $Cd(pn)Ni(CN)_4{\cdot}0.5NO_2C_6H_5$(pn: 1,2-diaminopropane=propylenediamine)은 사방정계 공간군 $Pn2_1$a로, a=13.868(5), b=26.591(4), c=7.840(1)${\AA}$, V=2891(1)${\AA}^3$, Z=4이며, 28000개의 독립적인 회절반점에 대한 R값은 0.054이다. 이 포접화합물의 host구조는 가지 달린 지방족 guest 분자를 포접한 포접화합물의 host 구조(T-type)와 같다. Nitrobenzene guest 분자는 T-type의 nodal형 턴넬속에 안정하게 포접되는데, 이는 node 위치체 pn-amino group이 놓이고, antinode 위치에 부피가 큰 방향조 고리가 놓이며, 이들 사이에 극성인 nitro group이 있기 때문이다. 턴넬형의 포접골간을 갖는 금속착체 $Cd(pn)Ni(CN)_4$의 host 구조가 가지 달린 방향족 guest 분자를 포접하고 있다.