• Title/Summary/Keyword: PLoS

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A Quantitative Analysis on PLoS ONE Articles Published by Authors Affiliated with Korean Institutions (PLoS ONE 학술지 게재 국내 기관 소속 연구자 논문의 계량적 분석)

  • Shim, Wonsik;An, Byoung-Goon;Park, Seong-Eun;Kim, Hyun Soo
    • Journal of the Korean Society for information Management
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    • v.37 no.2
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    • pp.47-69
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    • 2020
  • This research provides a quantitative analysis on research articles published in PLoS ONE, a multidisciplinary open access journal, by authors affiliated with Korean institutions. Korean authors published more than 6,500 research ariticles in the mega journal between 2006 and 2019. Korea is ranked the top 11th place in terms of article publishing in the journal. Most articles by Korean authors are concentrated in the biomedical fields. In recent years, the overall production of PLoS ONE has decreased as authors migrated to competing mega journals such as Scientific Reports and BMJ Open. The change might have been affected in part by the delay in the review period and the dropping impact factor score. The open access share of the Korean PLoS ONE authors of more than 10 articles hovers around 30%. However, there is a significant variation among researchers reaching up to 50% discrepancies. Among altmetrics provided by PLoS ONE, the saves are highly correlated with the views and the citations. On the contrary, the shares show low correlation with other use metrics. A follow up, survey questionnarie based research involving researchers who have published in PLoS ONE is planned in order to investigate author motivation and experience in the review process.

Identification of Contaminant Injection in Water Distribution Network

  • Marlim, Malvin Samuel;Kang, Doosun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2020.06a
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    • pp.114-114
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    • 2020
  • Water contamination in a water distribution network (WDN) is harmful since it directly induces the consumer's health problem and suspends water service in a wide area. Actions need to be taken rapidly to countermeasure a contamination event. A contaminant source ident ification (CSI) is an important initial step to mitigate the harmful event. Here, a CSI approach focused on determining the contaminant intrusion possible location and time (PLoT) is introduced. One of the methods to discover the PLoT is an inverse calculation to connect all the paths leading to the report specification of a sensor. A filtering procedure is then applied to narrow down the PLoT using the results from individual sensors. First, we spatially reduce the suspect intrusion points by locating the highly suspicious nodes that have similar intrusion time. Then, we narrow the possible intrusion time by matching the suspicious intrusion time to the reported information. Finally, a likelihood-score is estimated for each suspect. Another important aspect that needs to be considered in CSI is that there are inherent uncertainties, such as the variations in user demand and inaccuracy of sensor data. The uncertainties can lead to overlooking the real intrusion point and time. To reflect the uncertainties in the CSI process, the Monte-Carlo Simulation (MCS) is conducted to explore the ranges of PLoT. By analyzing all the accumulated scores through the random sets, a spread of contaminant intrusion PLoT can then be identified in the network.

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Analysis on the Open Access Policies, Publishing, and Archiving in the Field of Medicine (의학 분야 오픈 액세스 현황 분석을 통한 국내 의학 정보 활성화 방안)

  • Joung Kyoung-Hee
    • Journal of the Korean Society for Library and Information Science
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    • v.40 no.2
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    • pp.389-414
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    • 2006
  • This paper analyzes the current status of open access policies, publishing, and archiving in the field of medicine. Journals indexed in SCI are published by open access publishers such as BMC Ltd. and PLoS and then the research articles in those journals are archived in PMC and BMC. Also, funding institutions participate in developing open access as a new scholarly communication model and governments or independent funding institutions outside the country make policies for open access. But scholary communities in Korea do not develop their services in the level of a new scholarly communication model even though they open their journal articles on the homepages. This paper suggests several plans for the open access scholarly communication in the field of medicine in Korea.

Svstematic Study on the Genus Zacco (Pisces, Cyprinidae) 1. Genic Variation (피라미속(잉어목, 잉어과) 어류의 계통분류학적 연구 1. 유전적 변이)

  • 민미숙;양서영
    • The Korean Journal of Zoology
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    • v.34 no.4
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    • pp.557-570
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    • 1991
  • 일차 담수어류의 잉어과(Cyprinidae)에 속하는 Zacco속 어류 4종과 이와 근인관계가 가까운 Candid유속 어류 1종에 대한 유전적 변이를 조사하기 위하여, 한국, 일본 및 대만에서 채집된 개체를 대상으로 전기영동을 실시하여 24-28개의 유전자를 검출 분석하였다. 각 종의 유전적 변이 정도를 조사한 결과 Zaccoplotypus는 전 집단 평균 h: 1.22, p= 17. 52%, HD = 0.053 및 HD= 0.056으로서 조사한 전종중에서일근 변이가 가장 높았다. Z. pachycepholus의 유전적 변이 정도는 A= 1.17, p= 14.8%, HD: 0.026, HG=0.027로서 Z. ploDpus보다 변이 정도가 낮았고, Z. temminck와 Candidia barbata는 각기 A= 1.07, p =7.95%, HD = 0.011, HG = 0.013 및 A= 1.05, P= 3.7%, Hd: 0.013, HG = 0.011로서 변이 정도가 가장 낮았다. Z. Platypus의 경우 한국집단이 변이가 가장 높았으며 대만집단이 가장 낮았다. Zacco속과 Candid지속 어류의 평균 유전적 변이정도는 타어류의 유전적 변이보다 낮았으며 이는 한국산 담수어류중 잉어과 어류의 일반적인 특징이라 사료된다.

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Characterization of Scaled-up Low-Trans Shortening from Rice Bran Oil and High Oleic Sunflower Seed Oil with Batch Type Reactor (회분식반응기를 이용한 미강유, 팜스테아린과 고올레인산 해바라기씨유 유래 대량 제조된 저트랜스 쇼트닝의 특성 연구)

  • Kim, Ji-Young;Lee, Ki-Teak
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.3
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    • pp.338-345
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    • 2009
  • Scaled-up low-trans shortening (LTS) was produced by lipase-catalyzed interesterification. Blend of rice bran oil (RBO), palm stearin (PS) and high oleic sunflower seed oil (HO) with 1:2:0.9 (w/w/w) ratio was interesterified using immobilized lipase from Thermomyces lanuginosus (TLIM) in the batch type reactor at $65^{\circ}C$ for 24 hr, and physicochemical melting properties of LTS were compared with commercial shortening. Solid fat content (SFC) of commercial shortening (used as control) and LTS was similar at 9.56 and 8.77%, respectively, at $35^{\circ}C$. Major fatty acids in LTS were C16:1 (33.7 wt%), C18:1 (45.7 wt%) and C18:2 (13.4 wt%). Trans fatty acid content in the commercial shortening (4.8 wt%) was higher than that of LTS (0.5 wt%). After reverse-phase HPLC analysis, major triacylglycerol (TAG) species in LTS were POO, POP and PLO. Total tocopherol, ${\gamma}$-oryzanol and phytosterol contents in the LTS were 12.37, 0.43 and 251.38 mg/100 g, respectively. Hardness of LTS was similar to that of commercial shortening. Also, x-ray diffraction analysis showed coexistence of ${\beta}'$ and ${\beta}$ form in the LTS.

New Trend of Scholarly Communication : Open Access (학술 커뮤니케이션의 새로운 동향 : 자유이용을 중심으로)

  • Lee, Too-Young;Hwang, Ok-Gyung
    • Journal of Information Management
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    • v.34 no.2
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    • pp.1-23
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    • 2003
  • The serials pricing and licensing crises have caused the problem of limited access to scholarly information and the problem of its preservation. To cope with these crises, various types of scholarly communication models are under study now. Open Access is one of the possible solutions among these new trials. This study has investigated the history of Open Access, articulated the first considerations for the spread of Open Access, and proposed the role of librarians during the progress.

Islet function within a multilayer microcapsule and efficacy of angiogenic protein delivery in an omentum pouch graft

  • McQuilling, J.P.;Pareta, R.;Sivanandane, S.;Khanna, O.;Jiang, B.;Brey, E.M.;Orlando, G.;Farney, A.C.;Opara, E.C.
    • Biomaterials and Biomechanics in Bioengineering
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    • v.1 no.1
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    • pp.27-39
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    • 2014
  • We have previously described a new multilayer alginate microcapsule system, and the goals of the present study were to assess the in vitro function of islets encapsulated in its inner layer, and the angiogenic ability of FGF-1 delivered from the external layer in an omentum pouch. Following isolation and culture, islets were encapsulated in the inner core of microspheres ($500-600{\mu}m$ in diameter) with a semi-permeable poly-L-ornithine (PLO) membrane separating two alginate layers, and both unencapsulated and encapsulated islet function was assessed by a dynamic glucose perifusion. For angiogenesis experiments, one group of microcapsules without FGF-1 (control) and another (test) containing FGF-1 with heparin encapsulated in the external layer were made. One hundred microcapsules of each group were transplanted in Lewis rats (n = 5/group) and were retrieved after 14 days for assessment of angiogenesis. Glucose perifusion of unencapsulated and encapsulated islets resulted in similar stimulation indices. The release of FGF-1 resulted in increased vascular density compared to controls. In conclusion, islets encapsulated in the core of multilayer alginate microcapsules maintain functionality and the microcapsule's external layer is effective in delivery of FGF-1 to enhance graft neovascularization in a retrievable omentum pouch.

Autoxidative Stability of Triglyceride Molecular Species (트리글리세리드 분자종의 산화안정성에 관한 연구)

  • Yoon, Hyeung-Sik;Kim, Seon-Bong;Park, Yeung-Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.18 no.2
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    • pp.205-210
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    • 1989
  • The influence of triglyceride molecular species on autoxidation was investigated by determining the residual molecular species after incubating soybean oil triglycerides. The molecular species of soybean oil triglycerides were analyzed by capillary column gas chromatography and electron impact ionization mass spectrometry utilizing selected ion monitoring. The autoxidative stability of each molecular species in soybean oil triglycerides appeared to decrease in proportion to the increase in the number of double bonds present in the acyl residues, and it was affected by degree of unsaturation of fatty acid when the number of double bonds in triglyceride were the same. And it appeared to be enhanced by a decreases in the length of the saturated acyl chain present in the glycerides.

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Alteration of Phospholipase D Activity in the Rat Tissues by Irradiation (방사선 조사에 의한 쥐 조직의 포스포리파제 D의 활성 변화)

  • Choi Myung Sun;Cho Yang Ja;Choi Myung-Un
    • Radiation Oncology Journal
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    • v.15 no.3
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    • pp.197-206
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    • 1997
  • Purpose : Phospholipase D (PLD) catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid (PA) and choline. Recently, PLD has been drawing much attentions and considered to be associated with cancer Process since it is involved in cellular signal transduction. In this experiment, oleate-PLD activities were measured in various tissues of the living rats after whole body irradiation. Materials and Methods : The reaction mixture for the PLD assay contained $0.1\;\muCi\;1,2-di[1-^{14}C]palmitoyl$ phosphatidylcholine 0.5mM phosphatidylcholine, 5mM sodium oleate, $0.2\%$ taurodeoxycholate, 50mM HEPES buffer(pH 6.5), 10mM $CaCl_2$, and 25mM KF. phosphatidic acid, the reaction product, was separated by TLC and its radioactivity was measured with a scintillation counter. The whole body irradiation was given to the female Wistar rats via Cobalt 60 Teletherapy with field size of 10cmx loom and an exposure of 2.7Gy per minute to the total doses of 10Gy and 25Gy. Results : Among the tissues examined, PLD activity in lung was the highest one and was followed by kidney, skeletal muscle, brain, spleen, bone marrow, thymus, and liver. Upon irradiation, alteration of PLD activity was observed in thymus, spleen, lung, and bone marrow. Especially PLD activities of the spleen and thymus revealed the highest sensitivity toward $\gamma-rar$ with more than two times amplification in their activities In contrast, the PLD activity of bone marrow appears to be reduced to nearly $30\%$. Irradiation effect was hardly detected in liver which showed the lowest PLD activity. Conclusion : The PLD activities affected most sensitively by the whole-body irradiation seem to be associated with organs involved in immunity and hematopoiesis. This observation s1ron91y indicates that the PLD is closely related to the physiological function of these organs, Furthermore, radiation stress could offer an important means to explore the phenomena covering from cell Proliferation to cell death on these organs.

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