• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 추계학술대회
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• pp.1534-1539
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• 2004

This experiment has been carried out to measure the process of droplet formation between water phase fluid(PVA 3%) and organic phase fluid(oil) and vector fields measured by a Dynamic Micro-PIV method in the inside of a droplet while generated. Droplet length controlled by changing flow rate conditions in microchannel. Water-in-oil(W/O) droplets successfully generated at a Y junction and cross microchannel. But oil-in-water(O/W) droplets could not be formed at a Y junction microchannel. That is, PVA 3% flow could not be detached from the PDMS surface and ran parallel with oil flow. When PVA 3% flow rate was constant, droplet length and time period decreased as oil flow rate increased, but droplet frequency increased. When PVA 3% and oil flow rate ratio was constant, droplet length and time period decreased as flow rate increased, but droplet frequency increased. All that case, Standard deviation of droplet formation have less than 5% at averaged droplet length and regular-sized droplets were reproducibly formed.

• 한국가시화정보학회:학술대회논문집
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• 한국가시화정보학회 2004년도 Proceedings of 2004 Korea-Japan Joint Seminar on Particle Image Velocimetry
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• pp.119-124
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• 2004

Experimental study was conducted to characterize the flow effect of particle migration in a microchannel which can be used to deliver small amount of liquids, drugs, biological agents and particles in microfluidic devices. Fluorescent particles of $1\{mu}m$ diameter were used to obtain velocity profiles of the fluid in which large particles of $10\{mu}m$ diameter were suspended at different volume fraction of 0.6 and $0.8\%$. Measurements were obtained by using micro-PIV system which contains a Nd:YAG laser with a light of 532-nm wavelength, an inverted epi-fluorescent microscope and a cooled CCD camera to record particle images. The volume fraction of $\phi$ and the particle Reynolds number $Re_p$Rep were used as a parameter to assess the influence of the velocity profile of the suspensions. To expect the slip velocity between the particle and fluids, experiments were carried out at low volume fraction. It was shown that the velocity profile was not influenced by Rep but influenced by the volume fraction, which is in similar trend with the previous study.

• 한국가시화정보학회:학술대회논문집
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• 한국가시화정보학회 2007년도 추계학술대회
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• pp.109-113
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• 2007

Micro-PIV is a well-known method for measurement of two- dimensional, two-component velocity in the microfluidic devices. Lots of the micro fluidic devices generate three-dimensional flow and 3D measurement of velocity is helpful to understand the physics of micro flow phenomena. In this study, we developed new micro 3D measurement method by applying 2-frame PTV in stereoscopic micro system. In this study, we did the validation study of SMPTV by using the simulated flow model to verify the accuracy and the feasibility of measurement and compared with SMPIV method. The results showed that SMPTV provides better spatial resolution and measurement accuracy than SMPIV method.

• 한국가시화정보학회:학술대회논문집
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• 한국가시화정보학회 2007년도 추계학술대회
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• pp.77-83
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• 2007

This paper presents numerical and experimental works for simultaneous pumping and mixing small liquid using asymmetric microelectrode arrays, based on AC electroosmotic flows. To this end, four arrangements of electrode pairs were considered with diagonal/herringbone shapes. Numerical simulations were made of three-dimensional geometries by using the linear theory. The results indicated that the helical flow motions induced by the electrode arrays play a significant role in the mixing enhancement. The pumping performance was influenced by the slip velocity at the center region of the channel compared to that near the side walls. To validate the numerical predictions, the microfluidic devices were made through MEMS. The flow rate was obtained by using micro PIV, increasing the applied frequency. The electrolyte was potassium chloride solution. The flow patterns above electrodes were visualized to see lateral flow for mixing. The experimental results showed good agreements with the numerical predictions.

• 대한기계학회논문집B
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• 제35권8호
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• pp.825-829
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• 2011

본 연구에서는, 미소유체시스템 상에서 정밀한 유체 제어를 위해 입력압력이 변하여도 일정한 유량을 유지할 수 있는 수동형 유량제어기를 개발함에 있어, 주기적으로 변화하는 압력에 대한 유량제어기의 동적특성을 평가하였다. 압력 변화의 주기보다 짧은 시간 내에 유량을 측정하기 위하여 입자영상속도계(Particle Image Velocimetry, PIV) 방법을 이용하였다. 지름이 $0.7{\mu}m$ 인 형광입자가 담긴 탈이온수를 유량제어기에 공급하고, 펄스레이저와 형광현미경을 이용하여 $10{\mu}s$ 간격의 연속된 사진을 얻고 이를 분석하여 유량제어기를 통과한 후의 유체의 속도를 측정하였다. 개발된 유량제어기는 20kPa 과 50kPa 사이를 주기적으로 변화하는 60Hz 의 압력 하에서 0.194${\pm}$0.014m/s의 일정한 유속을 유지함을 실험적으로 확인하였다. 압력의 주파수를 1~60Hz 까지 변화시켜가며 수행한 실험에서도 유량제어기는 압력의 주파수에 상관없이 $5.82{\pm}0.29\;{\mu}l/s$ 의 일정한 유량 공급이 가능함을 확인하였다.

• JSTS:Journal of Semiconductor Technology and Science
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• 제1권4호
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• pp.239-247
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• 2001

The Fluorescence-Activated Cell Sorter (FACS) is a well-established instrument used for identifying, enumerating, classifying and sorting cells by their physical and optical characteristics. For a miniaturized FACS device, a disposable plastic microchip has been developed which has a hydrodynamic focusing chamber using soft lithography. As the characteristics of the spatially confined sample stream have an effect on sample throughput, detection efficiency, and the accuracy of cell sorting, systematic fluid dynamic studies are required. Flow visualization is conducted with a laser scanning confocal microscopy (LSCM), and three-dimensional flow structure of the focused sample stream is reconstructed from 2D slices acquired at $1\mutextrm{m}$ intervals in depth. It was observed that the flow structure in the focusing chamber is skewed by unsymmetrical velocity profile arising from trapezoidal cross section of the microchannel. For a quantitative analysis of a microscopic flow structure, Confocal Micro-PIV system has been developed to evaluate the accelerated flow field in the focusing chamber. This study proposes a method which defines the depth of the measurement volume using a detection pinhole. The trajectories of red blood cells (RBCs) and their interactions with surrounding flow field in the squeezed sample stream are evaluated to find optimal shape of the focusing chamber and fluid manipulation scheme for stable cell transporting, efficient detection, and sorting