• 한국지능시스템학회:학술대회논문집
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• 한국퍼지및지능시스템학회 2003년도 ISIS 2003
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• pp.353-357
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• 2003

Although it is more and more well accepted that modeling is a help for experimental biology, little is known about how to integrate physiological processes in general. The fact that no general theory exist in biology has big consequences, the most important being the difficulty to integrate biological phenomena. 1 will present a solution for the three dependent following issues: i) in an appropriate theoretical framework, integration consists in coupling models that each describe physiological mechanisms (formalization is a necessary condition to integration); ii) a biological theory with its own concepts leads to unifying principles in biology that are different from and complementary to physical principles; iii) such a formalized theory consists in a representation in terms of functional interactions and a specific formalism(S-Propagator). Hence a biological theory is of a topological and geometrical nature, in contrast to physical theories that are of a geometrical nature. An application to the interpretation of intelligence is proposed, based on the "intelligence"of movement.

• 한국동물학회:학술대회논문집
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• 한국동물학회 1996년도 한국생물과학협회 국제학술대회
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• pp.111.1-111
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• 1996

No Abstract, See Full Text

• 한국환경복원기술학회지
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• 제16권2호
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• pp.53-61
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• 2013

The present study elucidated the growth properties of Sasa borealis communities distributed in the lower layer of deciduous broadleaf forests in temperate zones and analyzed the correlation between the growth properties of S. borealis and positional environmental factors. The higher the culm height of S. borealis was, the higher the values of the leaf number, leaf area, and foliage layer thickness became. This might be because as the culm height of S. borealis increased, the acquisition of light sources became easier so that the biomass of leaves increased simultaneously for smooth anabolism. S. borealis seem to change their growth mode for smooth acquisition of light resources. The culm density of S. borealis and the leaf number, leaf area and foliage layer thickness of S. borealis did not show any clear correlation. The values of the culm height, leaf number, leaf area, and foliage layer thickness of S. borealis as the above altitude of the location of S. borealis increased. It seems like that growth conditions such as temperatures and winds are deteriorated as the above altitude of the location of S. borealis increased so that S. borealis becomes smaller. No clear correlations were shown between the physiochemical properties of soil and S. borealis' growth properties. It seems like that the growth of S. borealis complexly intertwined with diverse environmental factors and that due to the physiological integration of S. borealis, certain physiochemical properties do not unilaterally affect S. borealis' growth properties.

• 센서학회지
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• 제18권5호
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• pp.337-342
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• 2009

This paper describes a robust mobile u-healthcare system with multiple physiological signs measurement capability in real time with integration of WSN(wireless sensor network) technology and CDMA(code division multiple access) network. A cellular phone receives health data in WSN and performs local physiological signs analysis at a phone processor, and then transmits abnormal data to server for further detail or precise health signal evaluation by a medical doctor over a CDMA network. Physiological signs of the patients are continuously monitored, processed and analyzed locally at cellular phone process to produce useful medical information for diagnosis and tracking purposes. By local simple analysis in cellular phone processor we can save the data transmission cost in CDMA network. By using the developed integrate ubiquitous healthcare service architecture, patients can realize self-health checking so that the prevention actions can be taken earlier. Appropriate self-monitoring and self-management can cure disease and relieve pain especially for patients who suffer from chronic diseases that need long term observation.

• 대한감각통합치료학회지
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• 제9권2호
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• pp.51-60
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• 2011

목적 : ADHD아동의 감각자극에 대한 생리학적 반응특성은 감각자극의 종류, 측정도구, 그리고 반응으로 알아보고, 행동학적 특성은 측정도구, 빈도, 측정도구별로 공통된 문제 항목을 분석하여 ADHD아동의 감각자극에 대한 특성을 알아보고자 하였다. 연구방법 : 체계적 고찰방법을 사용하였다. 1990년 1월부터 2011년 12월 31일까지 학회지에 게재된 논문을 Riss4U, MEDLINE/PubMed, CINAH을 통해 검색하였다. 주요 검색어는 "ADHD, Children, Sensory processing, sensory integration, SP, SSP, SOR, TIE, CSP, SEP, EDR"으로 하였으며, 최종적으로 15개의 논문을 분석하였다. 결과 : 1. ADHD아동을 대상으로 감각자극에 대한 생리학적 반응에 관한 연구는 5개(33.33%)이고, 행동학적 반응에 관한 연구는 10개(66.67%)이며, 두 가지를 병행한 연구는 2개(13.33%)로 전체 15개(100%)논문을 분석하였다. 2. 생리학적 반응에 관한 연구 5개 중, 촉각과 고유 감각 자극을 사용한 연구는 3개, 후각, 청각, 시각, 촉각, 전정감각을 모두 사용한 연구는 2개였다. 3. 행동학적 특성에 관한 연구 10 중, SP는 5개, SSP는 3개, SOR은 2개, TIE는 1개, CSP는 1개이다. 4. ADHD아동의 감각자극에 대한 생리학적 반응특성은 일차감각피질의 손 영역에 있는 신경원세포의 활동전위에서 큰 반응을 보였다. 반응 시 초기에 큰 반응을 보였고 뒤로 갈수록 빠른 습관화를 보이는 것으로 나타났고, 회복 시에 많은 비 특이적 반응을 보였다. 5. 행동학적 반응특성은 부주의/산만, 전정감각처리, 지구력/근 긴장도 조절, 감정반응에 대한 감각입력 조절, 활력이 부족하고 허약함을 보이는 특성이 있었다. 결론 : ADHD아동의 감각자극에 대한 생리학적 반응 특성과 행동학적 특성을 아는 것은 ADHD아동의 감각조절 문제를 이해하는데 중요한 근거가 된다.

• 아시안잔디학회지
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• 제23권2호
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• pp.331-344
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• 2009

Buffalograss는 내한, 내서, 그리고 내한발에 우수한 주요 잔디 종 중 하나이다. 다양한 환경에서 buffalograss의 생리학적 조정(integration)을 이해하는 것은 균일한 잔디의 질을 도모하고 경종적 재배방법의 개발에 도움이 된다. 본 연구의 목적은 물 부족의 스트레스 처리에서의 buffalograss의 생리학적 조정과정에서 lipid peroxidation과 산화방지제의 연관성을 평가하였다. 한 실험에서 buffalograss는 네 개의 구분된 칸막이 성장 유닛의 중심에서 재배되었고, 일주일에 한번(+), 일주일에 두 번(-) 관수처리와 모래(S) 또는 피트(P)와를 혼합한 다섯 가지 토양 조합으로 처리하였다(P+S-P-S+, P+P+P+P+, S-S-S-S-, P-P-P-P-, and S+S+S+S+). 그 결과, 균일하게 혼합된 상토에서 생장한 줄기의 수가 네개의 단일 상토에 정착한 것보다 더 많았다. 두 번째 실험에서는 Hoagland 용액($S_o$), 또는 20% PEG-6000이 함유된 Hoagland용액($S_s$) 안에 하나의 라미트(무성생식체) 혹은 연결된 라마트를 다음과 같은 여러 가지 처리와 비교 실험하였다. 연결된 라미트들의 처리는 Hoagland 용액안의 어린 라미트($Y_{os}$)와 20%PEG-6000가 함유된 Hoagland 용액안의 성숙한 라미트($O_{os}$), Hoagland 용액 단독에 성숙한 라미트($O_{ys}$), 20%PEG-6000 함유된 Hoagland 용액안의 어린 라미트($Y_{ys}$)였다. Lipid peroxidation, antioxidants, proline은 각기 다른 수분 stress 정도에서 라미트들 간의 생리학적 활성을 보여 주었다. Superoxide dismutase (SOD), Guaiacol peroxidase (G-POD), malondi aldehyde (MDA), free proline의 활성도 처리 후 시간에 따라 상대적인 생리학적 활성을 보였다.

• 센서학회지
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• 제31권2호
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• pp.71-78
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• 2022

Wearable devices have the potential to revolutionize future medical diagnostics and personal healthcare. The integration of biosensors into scalable form factors allow continuous and noninvasive monitoring of key biomarkers and various physiological indicators. However, conventional wearable devices have critical limitations owing to their rigid and obtrusive interfaces. Recent developments in functional biocompatible materials, micro/nanofabrication methods, multimodal sensor mechanisms, and device integration technologies have provided the foundation for novel skin-interfaced bioelectronics for advanced and user-friendly wearable devices. Nonetheless, it is a great challenge to satisfy a wide range of design parameters in fabricating an authentic skin-interfaced device while maintaining its edge over conventional devices. This review highlights recent advances in skin-compatible materials, biosensor performance, and energy-harvesting methods that shed light on the future of wearable devices for digital health and personalized medicine.

• Molecules and Cells
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• 제44권12호
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• pp.861-878
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• 2021

The human genome contains many retroviral elements called human endogenous retroviruses (HERVs), resulting from the integration of retroviruses throughout evolution. HERVs once were considered inactive junk because they are not replication-competent, primarily localized in the heterochromatin, and silenced by methylation. But HERVs are now clearly shown to actively regulate gene expression in various physiological and pathological conditions such as developmental processes, immune regulation, cancers, autoimmune diseases, and neurological disorders. Recent studies report that HERVs are activated in patients suffering from coronavirus disease 2019 (COVID-19), the current pandemic caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection. In this review, we describe internal and external factors that influence HERV activities. We also present evidence showing the gene regulatory activity of HERV LTRs (long terminal repeats) in model organisms such as mice, rats, zebrafish, and invertebrate models of worms and flies. Finally, we discuss several molecular and cellular pathways involving various transcription factors and receptors, through which HERVs affect downstream cellular and physiological events such as epigenetic modifications, calcium influx, protein phosphorylation, and cytokine release. Understanding how HERVs participate in various physiological and pathological processes will help develop a strategy to generate effective therapeutic approaches targeting HERVs.

• ALGAE
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• 제29권4호
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• pp.321-331
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• 2014

Vertebrata lanosa is an abundant and obligate red algal epiphyte of Ascophyllum nodosum that forms part of a complex and highly integrated symbiotic system that includes the ascomycete, Mycophycias ascophylli. As part of ongoing studies to resolve interactions among species in the symbiosis, we used pulse amplitude modulation fluorimetry of chlorophyll a fluorescence, from photosystem II (PSII), to measure the maximum quantum yield ($F_v/F_m$) of PSII [$QY(II)_{max}$] and relative photosynthetic electron transport rates (rETR), as a function of light intensity, in order to evaluate the photosynthetic capacity of the two algal symbionts in the field and in the laboratory under different treatments. Our primary question was 'Is the ecological integration of these species reflected in a corresponding physiological integration involving photosynthetic process?' In the laboratory we measured changes in $QY(II)_{max}$ in thalli of V. lanosa and A. nodosum over one week periods when maintained together in either attached or detached treatments or when maintained separated from each other. While the $QY(II)_{max}$ of PSII of A. nodosum remained high and showed no significant variation among treatments, V. lanosa showed decreasing performance in the following conditions: V. lanosa attached to A. nodosum, V. lanosa in the same culture, but not attached to A. nodosum, and V. lanosa alone. These results are consistent with observations in which rETR was reduced in V. lanosa maintained alone versus attached to A. nodosum. Values for $QY(II)_{max}$ in V. lanosa measured in the field in fully submerged thalli were similar to those measured in the laboratory when V. lanosa was attached to it obligate host A. nodosum. Our results provide evidence of a physiological association of the epiphyte and its host that reflects the known ecology.

• 대한물리의학회지
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• 제5권3호
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• pp.301-312
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• 2010

Purpose : The purpose of this study was to determine Exercisely the effects of applying an Integrated Exercise Program (IEP) with the adapted use of Thera-Band exercise sets to Korean seniors on their improvement in their physical strength (PS), daily living ability (ADL and IDAL). Methods : The Exercise group consisted of 30 Korean seniors of 65 years of age or older, while the control group had another 30 Korean seniors with comparable aging. The Exercise group received the IEP for 50 to 60 minutes per session, three sessions per week, for a duration of consecutive 12 weeks. Results : This confirms the beneficial effects of the IEP on their MA and PS, and their improvement in PS (p<.05), in turn, can improve their IADL (p<.05). The results of this study indicate the potentialities for IEP to help Korean seniors of 65 years or older to improve their PS, ADL and IADL. Conclusion : The IEP is within the physical and financial capabilities of Korean seniors, can be designed and modified and adjusted according to their individual physiological conditions. Sustained, regular exercises under IEP are expected to help resolve physiological issues of aging of Korean seniors.