• Title/Summary/Keyword: PGI

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A test of the hybrid origin of Korean endemic Sedum latiovalifolium (Crassulaceae) (한국특산 태백기린초(돌나물과)의 교잡 기원에 대한 검증)

  • Yoo, Young-Gi;Park, Ki-Ryong
    • Korean Journal of Plant Taxonomy
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    • v.46 no.4
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    • pp.378-391
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    • 2016
  • Eighteen morphological characters from 40 populations and ten isozyme loci from 35 populations of Sedum latiovalifolium and related species were examined to investigate the degree of morphological and genetic variation. The high-frequency marker alleles $MDH-2^a$ and $PGI-1^a$ in S. aizoon, S. kamtschaticum, and S. zokuriense did not appear in the populations of S. latiovalifolium. In addition, the high-frequency allele ($MDH-2^c$) in S. latiovalifolium appeared at a very low frequency in other subg. aizoon species. Thus, the isozyme data did not support a hybrid origin of S. latiovalifolium from S. aizoon with S. kamtschaticum. The results of an unweighted pair-group method using the arithmetic average method and a principal components analysis using morphological data also did not support a hybrid origin of S. latiovalifolium. However, our data strongly suggest that some individuals from the populations found in the Gumdaebong area were most likely hybrids due to introgression between S. latiovalifolium and S. kamtschaticum or S. aizoon and S. kamtschaticum.

Genetic Variation of Isozymes in Populations of Pinus densiflora and Pinus thunbergii Naturally Distributed in Kyungpook Province (경북지방(慶北地方) 소나무 및 곰솔집단(集團)의 동위효소(同位酵素)에 의한 유전변이(遺傳變異))

  • Son, Doo-Sik;Hong, Sung-Chun;Yeo, Jin-Kie;Ryu, Jang-Bal
    • Journal of Korean Society of Forest Science
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    • v.78 no.4
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    • pp.345-359
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    • 1989
  • This study was conducted to estimate genetic variation of Pinus densiflora in Kyungpook province which shows morphological variation between northern and southern types. Six isozymes sueh as IDH, ME, PGI, ADH, GOT and LAP was analyzed using megagametophyte tissue of seeds by electrophoresis and 16 populations of Pinus densiflora and 5 of Pinus thunbergii were tested. The results obtained were as follows ; 1. In P. densiflora, 13 Loci were found in 6 isozymes and 8 loci of them were polymorphic, having 24 alleles, while in Pinus thunbergii, there were 18 alleles detected from 6 loci among the same number of loci as in Pinus densiflora. 2. The genotypic frequency in Pinus densiflora vary slightly among populations for some isozymes, but most of them satisfied the law of Hardy-Weinherg equilibrium, while some populations such as Youngil for ADH and LAY, Youngyang for ADH and Bonghwa for LAY did not follow the law and showed high fixation index values and homozygosities higher than expected. 3. The variation among populations based on the genetic distance was small except populations of Youngju, Baegam, Gyungju and Sangju, however they could be clustered by three groups : northern Kyungpook group including Mt. Taebak, inland Kyungpook group represented by Sungju, Eusung and Kumleung population and coastal Kyungpook group represented by Baegam and Gyungju population. 4. No significant difference was found in 6 isozymes between northern and southern types of Pinus densiflora which was morphologically different. 5. The frequency of heterozygous loci per tree was higher in Pinus densiflora especially for ME-A and A DH-B, while that of homozygous loci was higher in Pinus thunbergii except for ADH-B, LAY-B and PGI-B locus.

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An Efficient Synthesis of 12-epi-Carbacyclins Using a Palladium-Mediated Tandem Alkene Insertion Strategy

  • Lee, Nam-Ho;Larock, Richard C.
    • Bulletin of the Korean Chemical Society
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    • v.23 no.1
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    • pp.86-92
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    • 2002
  • A short synthesis of novel prostanoids, 12-epi-carbacyclins 3 and 24, has been accomplished using palladium chemistry as a key step. The silyl enol ether 10a prepared through organopalladium chemistry has been allowed to react with 1-octen-3-one in the presence of $Pd(OAc)_2$ to give compound 12 in a single step. The unusual chemo- and stereoselective reduction of the ${\alpha},{\beta}$-unsaturated ketone in 12 has been effected with (S)-BINALH. Subsequent desilylation and Wittig reaction have provided the Subsequent desilylation and Wittig reaction have provided the $PGI_2$ analogues 3 and 24.

Review of Vascular Endothelial Growth Factor (혈관내피성장인자에 관한 고찰)

  • Kim, Souk-Boum;Kim, Dong-Hyun;Song, Ju-Young;Kim, Jin-Sang
    • The Journal of Korean Physical Therapy
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    • v.14 no.1
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    • pp.219-226
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    • 2002
  • Vascular endothelial growth factors(VEGFs) constitute a group of structurally and functionally related growth factor that modulate many important physiological functions of endothelial cells, especially angiogenesis. This paper explain substance, which participate in signaling transduction of VEGF, including Bcl-2, caspase, focal adhesion kinase(FAK), integrin ${\alpha}v{\beta}3$, MAP kinase, nitric oxide(NO)and prostacyclin(PGI2). Physical therapy enhance angiogenesis for repairment of injury which as wound healing, muscle contusion, cerebrovascular disease, rheumatoid arthritis. Therefore this review assist understanding for mechanism of physical therapy as therapeutic angiogenesis.

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Isozymic Variation of Local Populations in the 3 Species of Phyllostachys (왕대속 3종의 지역개체군간 동위효소변이)

  • 김창호;하미영;이호준
    • The Korean Journal of Ecology
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    • v.21 no.3
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    • pp.301-307
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    • 1998
  • Intraspecific and interspecific isozyme variations and their relationship of 16 local populations in 3 species of Phyllostachys, that is, P. bambusoides, P. nigra var. henonis and P. pubescens were investigated by multi-variate analysis. Leaf isozymes of Phyllostachys such as 6-PGD (6-phosphogluconate dehydrogenase), MDH (malate dehydrogenase), PGI (phosphoglucoisomerase), PRX (peroxidase), PGM (phosphoglutamase), IDH (isocitrate dehydrogenase) showed electrophoretic variations in the number of zymotypes (7, 6, 6, 9, 3 and 5, respectively). In the cluster analysis on the isozymic characteristics, 16 populations were classified into 3 species at the euclid genetic distance of 2.041. P. nigra var. henonis and P. bambusoides were clustered first at 2.813 and then P. pubescens at 3.001. So far, 3 local types of intraspecific ariation were found in P. nigra var. henonis and P. bambusoides.

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EFFECT OF KOREAN RED GINSENG ON EICOSANOID BIOSYNTHESIS IN PLATELETS AND VASCULAR SMOOTH MUSCLE CELLS

  • Tamura Y.;Hirai A.;Terano T.;Tahara K.;Saitoh J.;Kondo S.;Samukawa K.;Yoshida S.
    • Proceedings of the Ginseng society Conference
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    • 1993.09a
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    • pp.28-29
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    • 1993
  • From in vivo and in vitro experiments using Korean Red Ginseng and its main components. ginsenoside saponins, it was found that ginesenoside may exerts its anti-thrombotic action by decreasing $TXA_2$ formation in platelets and increasing $PGI_2$ formation in vascular walls. This may certainly contribute to prevention and development of atherosclerosis and thrombosis by administration of Korean Red Ginsengs.

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Ultra-precision Grinding Machining of Glass Rod Lens Core With Aspheric (비구면 Glass Rod 렌즈 금형의 초정밀 연삭가공)

  • Kim, Woo-Soon;Kim, Dong-Hyun
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.18 no.1
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    • pp.76-82
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    • 2009
  • To obtain the surface roughness with nano order, we need a ultra-precision machine, cutting condition, and materials. In this paper, the cutting condition for getting nano order smooth surface of core have been examined experimentally by the ultra-precision machine and diamond wheels. The effects of the cutting velocity, the feed rate and depth of cut on the surface roughness were studied. And also, the surface roughness was measured by the Form Talysurf series PGI 840. The champion data of developed core was surface roughness Rmax 24.6nm, figure accuracy Rmax 68.9nm.

Endothelium-derived Relaxing Factors of Small Resistance Arteries in Hypertension

  • Kang, Kyu-Tae
    • Toxicological Research
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    • v.30 no.3
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    • pp.141-148
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    • 2014
  • Endothelium-derived relaxing factors (EDRFs), including nitric oxide (NO), prostacyclin ($PGI_2$), and endothelium-derived hyperpolarizing factor (EDHF), play pivotal roles in regulating vascular tone. Reduced EDRFs cause impaired endothelium-dependent vasorelaxation, or endothelial dysfunction. Impaired endothelium-dependent vasorelaxation in response to acetylcholine (ACh) is consistently observed in conduit vessels in human patients and experimental animal models of hypertension. Because small resistance arteries are known to produce more than one type of EDRF, the mechanism(s) mediating endothelium-dependent vasorelaxation in small resistance arteries may be different from that observed in conduit vessels under hypertensive conditions, where vasorelaxation is mainly dependent on NO. EDHF has been described as one of the principal mediators of endothelium-dependent vasorelaxation in small resistance arteries in normotensive animals. Furthermore, EDHF appears to become the predominant endothelium-dependent vasorelaxation pathway when the endothelial NO synthase (NOS3)/NO pathway is absent, as in NOS3-knockout mice, whereas some studies have shown that the EDHF pathway is dysfunctional in experimental models of hypertension. This article reviews our current knowledge regarding EDRFs in small arteries under normotensive and hypertensive conditions.

Geographical indication and its trade practices in Europe, USA and China (유럽, 미국, 중국의 지리적 표시 제도 및 산업적 현황)

  • Cheon, Jae Eun;Xin, Yimei
    • Food Science and Industry
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    • v.54 no.4
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    • pp.246-259
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    • 2021
  • Various countries established Geographical Indication (GI) system to protect the right and traditionality of their native products. The regulations vary by country but can be divided accordingly: Protection by trademark systems such as in USA, Special Protection for Geographical Indication as in EU, Protection by both schemes as in China and Korea. Within the systems, countries provide diverse schemes such as PDO and PGI in EU depending on the scope of the product. However, GI system in Korea provides one definition which only protects products that express definite tie to its territory of origin, preliminary with the origin of the ingredient. It is necessary for the government and industry to seek ways to revitalize the local economy in the global market and increase the number of GI products by aligning GI systems with foreign countries and support mutual bilateral agreement.

The characteristics of selected trees of putative hybrid pines between Pinus thunbergii and Pinus densiflora (곰솔과 소나무의 자연잡종(自然雜種)으로 추정(推定)되는 잡종(雜種)소나무의 특성(特性))

  • Son, Doo Sik;Kwon, Chil Yong;Park, Sang Jun
    • Journal of Korean Society of Forest Science
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    • v.79 no.2
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    • pp.127-137
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    • 1990
  • This study was carried out to investigate some characteristics of selected trees recognized as natural hybrid between Pinus densiflora and Pinus thunbergii for improving resistance to pine leaf gall midge. The results obtained were as follows. l. In the mean annual increment and the growth in the period of latest 5 years of DBH, hybrid pines showed intermediate value of the parents, Pinus densiflora and Pinus thunbergii. However, there was remarkable variation among individuals of hybrid pine. 2. The trees having resin duct index(RDI) value larger than 0.1 for the position of resin duct in needle was classified as hybrid pine. The leaf and leaf sheath of Pinus thunbergii was longer than that of Pinus densiflora and the distance between rows of stomata on needles of Pinus thunbergii was longer than that of Pinus detasiflora, and the values of those observations on hybrid pine were intermediate between the parent species. However, differences among individual was observed. 3. In the size of cone and seed, and weight of 1000 seeds, like in the leaf characteristics, Pinus thunbergii showed higher value than Pinus densiflora and those values of hybrid were intermediate between the parent species. 4. Assuming isoenzyme ADH-$B_2$, ME-$A_2$, PGI-$B_1$, and PGI-$B_2$ alleles observed in the hybrids were introgressed from Pinus thunbergii, the hybrid pine can be easily identified by these isoenzyme alleles. However, the individuals which do not have those alleles can not be identified.

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