• Title/Summary/Keyword: PFM

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Effect of Pleurotus ferulae Extracts on Viability of Human Lung Cancer and Cervical Cancer Cell Lines

  • Choi DuBok;Cha Wol-Suk;Kang Si-Hyung;Lee Byoung-Rai
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.9 no.5
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    • pp.356-361
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    • 2004
  • When SiHa cells were incubated for varying periods of time with extracts of PFF and PFM, the cytotoxicity of the ethanol extracts of PFF was higher than those of the other extracts. These results indicated that the extracts from fruiting bodies of p. ferulae contain antitumor Substances. When A549, SiHa and HeLa cells were incubated with different concentrations of PFF and PFM extracts, the ethanol extracts of PFF showed strong cytotoxicity against A549 tells at concentrations over $10{\mu}g/mL$ and against SiHa and HeLa cells at concentrations over $40{\mu}g/mL$. However, the differences in the cytotoxic effects of the hot water and ethanol extracts of PFM and the hot water extracts of PFF on all 3 cancer cells were not significant. Also, the PFF ethanol extracts induced synergistic effects on the TRAIL-induced apoptosis in A549 cells, which were strongly resistant to TRAIL. These results indicated that ethanol extracts of PFF were the most prominent antitumor agents toward lung cancer cells (A549).

The effect of the gold based bonding agents on the bond between Ni-Cr alloys and ceramic restorations (Ni-Cr합금과 도재간의 결합력에 gold-based bonding agent가 미치는 영향)

  • Lee, Jung-Hwan;Joo, Kyu-Ji
    • Journal of Technologic Dentistry
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    • v.29 no.2
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    • pp.213-223
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    • 2007
  • The success of a porcelain fused to metal (PFM) restoration depends upon the quality of the porcelain-metal bond. The adhesion between metal substructure and dental porcelain is related to the diffusion of oxygen to the reaction layer formed on cast-metal surface during firing. The purposed of this investigation was to study the effects of gold based bonding agent on Ni-Cr alloy-ceramic adhesion between porcelain matrix, gold based bonding agent and metal substructure interface. gold based bonding agent have been applied as an intermediate layer between a metal substructure and a ceramic coating. gold based bonding agent(Aurofilm NP, Metalor, Swiss) was applied on Ni-Cr alloy surface by four method. Surfaces only air abraded with 110${\beta}\neq$ Al2O3 particles were used as control. metal ceramic adhesion was evaluated by a biaxial flexure test(N=5) and volume fraction of adherent porcelain was determined by SEM/EDS analysis. Result of this study suggest that the layering sequence of gold based bonding agent is very important and can improve porcelain adherence to PFM.

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Probabilistic Damage Mechanics Assessment of CANDU Pressure Tube using Genetic Algorithm (유전자 알고리즘을 이용한 CANDU 압력관의 확률론적 손상역학 평가)

  • Ko, Han-Ok;Chang, Yoon-Suk;Choi, Jae-Boong;Kim, Young-Jin;Kim, Hong-Key;Choi, Young-Hwan
    • Proceedings of the KSME Conference
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    • 2008.11a
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    • pp.192-192
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    • 2008
  • As the lifetime of nuclear power plants (NPPs) reaches design life, the probability for fatal accidents increases. Most of accidents are known to be caused by degradation of mechanical components. Pressure tubes are the most important components in CANDU reactor. They are subjected to various aging mechanisms such as delayed hydride cracking (DHC), irradiation and corrosion, etc. Therefore, the integrity of pressure tube is key concern in CANDU reactor. Up to recently, conventional deterministic approaches have been utilized to evaluate the integrity of components. However, there are many uncertainties to prevent a rational evaluation. The objective of this paper is to assess the failure probability of pressure tube in CANDU. To do this, probability fracture mechanics (PFM) analysis based on the Genetic Algorithm (GA) is performed. For the verification of the analysis, a comparison of the PFM analysis using a commercial code and mathematical method is carried out.

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Application of Probabilistic Fracture Mechanics Technique Using Monte Carlo Simulation (몬테카를로 시뮬레이션을 이용한 확률론적 파괴역학 수법의 적용성 검토)

  • Lee, Joon-Seong;Kwak, Sang-Log;Kim, Young-Jin
    • Journal of the Korean Society for Precision Engineering
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    • v.18 no.10
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    • pp.154-160
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    • 2001
  • For major structural components periodic inspections and integrity assessments are needed for the safety. However, many flaws are undetectable because sampling inspection is carried out during in-service inspection. Probabilistic integrity assessment is applied to take into consideration of uncertainty and variance of input parameters arise due to material properties and undetectable cracks. This paper describes a Probabilistic Fracture Mechanics(PFM) analysis based on the Monte Carlo(MC) algorithms. Taking a number of sampling data of probabilistic variables such as fracture toughness value, crack depth and aspect ratio of an initial surface crack, a MC simulation of failure judgement of samples is performed. for the verification of this analysis, a comparison study of the PFM analysis using a commercial code, mathematical method is carried out and a good agreement was observed between those results.

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Ferroelectricity of Bi-doped ZnO Films Probed by Scanning Probe Microscopy

  • Ben, Chu Van;Lee, Ju-Won;Kim, Jung-Hoon;Yang, Woo-Chul
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.02a
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    • pp.323-323
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    • 2012
  • We present ferroelectricity of Bi-doped ZnO film probed by piezoresponse force microscopy (PFM), which is one of the Scanning Probe Microscopy techniques. Perovskite ferroelectrics are limited to integration of devices into semiconductor microcircuitry due to hard adjusting their lattice structure to the semiconductor materials. Transition metal doped ZnO film is one of the candidate materials for replacing the perovskite ferroelectrics. In this study, ferroelectric characteristics of the Bi-doped ZnO grown by pulsed laser deposition were probed by PFM. The polarization switching and patterning of the ZnO films were performed by applying DC bias voltage between the AFM tips and the films with varying voltages and polarity. The PFM contrast before and after patterning showed clearly polarization switching for a specific concentration of Bi atoms. In addition, the patterned regions with nanoscale show clearly the local piezoresponse hysteresis loop. The spontaneous polarization of the ZnO film is estimated from the local piezoresponse based on the comparison with LiNbO3 single crystals.

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Plasma Facing Material 흡착기체의 정량적 분석을 위한 Thermal Desorption Analyzer (TDA) 개념 설계

  • Kim, Hui-Su;On, Yeon-Gil;Lee, Seok-Gwan;Choe, Min-Sik;No, Seung-Jeong;Gwon, Jin-Jung;Park, Jun-Gyu;Lee, Cheol-Ui
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.02a
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    • pp.513-513
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    • 2012
  • 핵 융합로의 대면재질(Plasma Facing Material; PFM)은 고온의 플라즈마와 고 에너지의 이온들에 지속적으로 노출 된다. 특히 PFM은 흡착되는 기체 등에 의한 부식과 변형이 발생할 수 있다. 현재 핵 융합로 내부의 PFM으로 고려되고 있는 재질 중 하나인 고순도 탄소타일의 경우 고온의 수소동위원소 플라즈마에 직접적으로 노출되므로 이에 의한 탄소타일에 흡착되는 수소 등의 기체에 대한 정량적인 분석방법이 필요하다. 본 연구는 고순도 탄소타일 등과 같은 플라즈마 대면재료에 흡착되어 있는 물질의 정량적 분석이 가능한 TDA (Thermal Desorption Analyzer)의 개념 설계에 관한 것이다. TDA는 고온 가열($800^{\circ}C$ 이상) 및 시료 장착부 및 초고진공(~10-9 torr) 및 측정부의 두 부분으로 구성 하였다. TDA 설계시 고온 가열 및 시료 장착부는 시료 내부에 흡착되어 있는 기체의 효과적 탈착을 위한 가열 및 시료의 모양에 영향을 받지 않는 장착방법, 시료 장착부의 outgassing rate를 최소화 하는 재질 선정 등을 고려하였으며, 초고진공(~10-9 torr) 및 측정부는 초고진공 유지방법, 터보펌프 배기속도 실측을 위한 구조, 진공측정 ion 게이지, 잔류가스분석기(Residual Gas Analyzer)의 최적위치 설정 등을 고려하여 설계하였다. 개념 설계된 TDA에 대하여 발표하고자 한다.

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The effect of vent on the marginal discrepancy of the PFM base metal castings (Vent의 형성이 도재전장 비귀금속합금 주조체의 변연부 적합도에 미치는 영향)

  • Kim, Tae-Suk;Lee, Sung-Uk;Oh, Sae-Yoon;Kim, Woong-Chul;Kim, Ji-Hwan;Yoo, Jin-Ho
    • Journal of Technologic Dentistry
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    • v.23 no.1
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    • pp.45-53
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    • 2001
  • This study was performed to investigate the effect of vent on the marginal discrepancy of PFM base metal castings. Eighteen identical wax patterns of a maxillary 3 unit anterior bridge were fabricated. Nine cases out of them were vented with $\phi$2.5mm sprue wax, for direct comparison as to the marginal discrepancy of the castings with the other non vented 9 ones. The mean value of marginal discrepancies of the vented castings was $85.02{\pm}25.57{\mu}m$, and that of the non vented was $163.21{\pm}69.88{\mu}m$ respectively. Statistical analysis revealed that marginal discrepancy of the vented casting was significantly reduced(p<0.05).

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Integrity Assessment of Sharp Flaw in CANDU Pressure Tube Using Probabilistic Fracture Mechanics (확률론적 파괴역학을 도입한 CANDU 압력관의 예리한 결함에 대한 건전성평가)

  • Lee, Jun-Seong;Gwak, Sang-Rok;Kim, Yeong-Jin;Park, Yun-Won
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.26 no.4
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    • pp.653-659
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    • 2002
  • This paper describes a probabilistic fracture mechanics(PFM) analysis based on Monte Carlo(MC) simulation. In the analysis of CANDU pressure tube, the depth and aspect ratio of an initial semi-elliptical surface crack, a fracture toughness value and delayed hydride cracking(DHC) velocity are assumed to be probabilistic variables. As an example, some failure probabilities of piping and CANDU pressure tube are calculated using MC method with the stratified sampling MC technique, taking analysis conditions of normal operations. In the stratified MC simulation, a sampling space of probabilistic variables is divided into a number of small cells. For the verification of analysis results, a comparison study of the PFM analysis using other commercial code is carried out and a good agreement was observed between those results.

High-Frequency Induction Heating System Design of a PFM and PWM method using Fuzzy Control (퍼지제어기를 이용한 PFM 방식과 PWM방식의 고주파 유도가열기의 설계)

  • 장종승;설재훈;박종오;임영도
    • Journal of the Korean Institute of Intelligent Systems
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    • v.8 no.2
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    • pp.43-49
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    • 1998
  • This paper describes a phase-shift pulse-width modulation and pulse-frequency modulation seriesresonant high-frequency inverter using IGBT for the power control of high-frequency inductionheating using fuzzy, which is practically applied for 2 0- 5~0 0~~ ~in 1d uction-heating and meltingpov~er supply in industrial fields. The adaptive frequency tracking based phase-shifting PWMregillation scheme is presented in order to minimize switching losses. The trially-producedbreadboards using IGBT are succesfully demostrated and discussed.discussed.

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Comparison between Passive Flux Meters and Borehole Dilution Tests to Estimate Groundwater Flux in a Karst Aquifer (플럭스미터와 단공희석시험을 이용한 카르스트 대수층 내 지하수 플럭스 측정 비교)

  • Lee, Juyeon;Yang, Minjune
    • Economic and Environmental Geology
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    • v.53 no.5
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    • pp.543-552
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    • 2020
  • In this study, we measured groundwater fluxes with a passive flux meter and a borehole dilution test in the Upper Floridan Aquifer. In addition, the feasibility of the passive flux meter is also evaluated within matrix and non-matrix zones. The results of the PFM (5.96 ± 1.75 cm/day) showed good agreement with those of the BHD (4.68 ± 2.99 cm/day) in matrix zones, whereas the results of the PFM (9.94 ± 0.90 cm/day) showed poor agreement with those of the BHD (1817.37 ± 1795.50 cm/day) in non-matrix zones. We assumed that the groundwater passes through the sorbent material inside the PFM. However, it could not pass through the sorbent when the groundwater flux is faster than 11 cm/day. The flow might bypass between monitoring well and the PFM. The PFM used in this study might be suitable for measuring the groundwater fluxes under 11 cm/day. Therefore, more extensive research is needed in the future to measure fast groundwater fluxes (> 11 cm/day).