• Title/Summary/Keyword: PFC 용액

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Enhancement of Gas Transfer Efficiency in an Intravascular Lung Assist Device using Blood Substitutes (혈관내의 폐보조장치에서 혈액대용물질을 사용한 기체전달 효율향상)

  • 김기범;박재관;권대규;정경락;이삼철
    • Journal of Biomedical Engineering Research
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    • v.24 no.5
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    • pp.391-399
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    • 2003
  • Intravascular oxygenation represents an attractive. alternative support modality for therapy originated with acute respiratory distress syndrome(ARDS). However. the clinical study concluded that more gas exchange was needed for intravascular oxygenation to be clinically effective in ARDS treatment. In this study, we tried to enhance gas exchange on the VIVLAD using microencapsulation of hemoglobin and perfluorocarbon emulsion(PFC emulsion). Blood gas measurements were performed by collecting blood samples from the arterial and venous sides of the circuit, and processing them in a blood/gas analyzer. The function of hemosome. blood/hemosome mixed solution. and blood/PFC emulsion mixed solution were tested by an oxygen dissociation curve using a blood/gas analyzer. As a result, it was shown that the oxygen transfer of hemosome and blood/hemosome mixed solution were higher than that of whole blood. Also. it showed that the carbon dioxide transfer of whole blood/PFC emulsion mixed solution was higher than that of others. Therefore, we determined that hemosome and PFC emulsion could increase oxygen transfer and carbon dioxide transfer. respectively.

PFC Ultrasonic Decontamination Efficiency on the Various Types of Metal Specimens (금속 시편 형태에 따른 PEC 초음파 제염 성능)

  • Won Hui-Jun;Kim Gye-Nam;Jung Chung-Hun;Park Jin-Ho;Oh Won-Zin
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.3 no.4
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    • pp.293-300
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    • 2005
  • Ultrasonic decontamination of the type 304 stainless steel specimen loosely contaminated with $Eu_2O_3$ powders was investigated. Decontamination factors (DFs) by the three kinds of ultrasonic media such as water, pure PFC (Pefluorocarbon, $C_7F_{16}$) and a mixed solution of $99.9\;vol\%\;PFC\;and\;0.1\;vol\%$ anionic surfactant were determined. The determined DF values were 20, 50 and 200, respectively. This significant difference in the decontamination factors for the different decontamination solution was well explained by the surface tension of the media as well as the interaction between the positively charged surface of $Eu_2O_3$ powders and the anionic surfactant. Ultrasonic decontamination behavior of the loosely contaminated metal specimens such as plate, pipe, welding specimen and crevice specimen in the mixed solution of PFC and anionic surfactant was also investigated. The contaminants were completely removed for the tested specimens except for the longest specimen. For 6-cm long pipe specimen, however, $98.5\%$ of the contaminants were removed.

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The Separation of Particulate within PFC Decontamination Wastewater Generated by PFC Decontamination (PFC 제염 후 발생된 제염폐액 내 오염입자의 제거)

  • Kim Gye-Nam;Lee Sung-Yeol;Won Hui-Jun;Jung Chong-Hun;Oh Won-Zin;Park Jin-Ho;narayan M.
    • Proceedings of the Korean Radioactive Waste Society Conference
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    • 2005.06a
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    • pp.32-39
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    • 2005
  • When PFC(Perfluorocarbonate) decontamination technology is applied to removal of radioactive contaminated particulate adhered at surface during the operation of nuclear research facilities, it is necessary to develop a filtration equipment to reuse of PFC solution due to high price, also to minimize the volume of second wastewater. Contaminated characteristics of hot particulate was investigated and a filtration process was presented to remove suspended radioactive particulate from PFC decontamination wastewater generated on PFC decontamination. The range of size of hot particulate adhered at the surface of research facilities measured by SEM was $0.1{\sim}10{\mu}m$. Hot particulate of more than $2{\mu}m$ in PFC contamination wastewater was removed by first filter and then hot particulate of more than $0.2{\mu}m$ was removed by second filter. Results of filter experiments showed that filtration efficiency of PVDF(Poly vinylidene fluoride), PP(Polypropylene), Ceramic filter was $95{\sim}97\%$. A ceramic filter showed a higher filtration efficiency with a little low permeate volume. Also, a ceramic of inorganic compound could be broken easily on experiment and has a high price but was highly stable at radioactivity in comparison of PVDF and PP of a macromolecule which generate $H_2$ gas in alpha radioactivity environment.

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Development and Performance Evaluation of a Filtration Equipment to Reuse PFC Waste Solution Generated on PFC Decontamination (PFC 제염 시 발생된 PFC 폐액의 재사용을 위한 여과장치 개발 및 성능평가)

  • Kim Gye-Nam;Jeong Cheol-Jin;Won Hui-Jun;Choi Wang-Kyu;Jung Chong-Hun;Oh Won-Zin;Park Jin-Ho
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.4 no.2
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    • pp.161-170
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    • 2006
  • PFC(Perfluorocarbon) decontamination process is one of best methods to remove hot particulate adhered on the inner surface of hot cell and surface of equipment in hot cell. It was necessary to develop a filtration equipment to reuse the PFC waste solution generated on PFC decontamination due to the high cost of PFC solution and for minimization of the volume of second waste solution. The filtration equipment was developed to remove hot particulate in PFC waste solution. It was made suitable size and weight in consideration of hot cell gate and crane. And it has wheels for easy movement. Flux of the filtration equipment decreased with particulate concentration increase. It consists of pre-filter($1.4{\mu}m$) and final-filter($0.2{\mu}m$) for protection of the flux decrease along filtration time. It treatment capacity of waste solution is 0.2 L/min.

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Membrane Characteristics for Removing Particulates in PFC Wastes (PFC제염폐액 내의 미립자 제거를 위한 여과막의 특성 연구)

  • Kim Gye-Nam;Lee Sung-Yeol;Won Hui-Jun;Jung Chong-Hun;Oh Won-Zin;Park Jin-Ho
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.3 no.2
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    • pp.149-157
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    • 2005
  • PFC(Perfluorocarbon) decontamination process is one of best methods to remove hot particulate adhered at inside surface of hot cell and surface of equipment in hot cell. It was necessary to develop a particulate filtration equipment to reuse PFC solution used on PFC decontamination due to its high cost and to minimize the volume of second wastewater. Contamination characteristics of hot particulate were investigated and then a filtration process was presented to remove hot particulate in PFC solution generated through PFC decontamination process. The removal efficiency of PVDF(Poly vinylidene fluoride), PP(Polypropylene), Ceramic(Al$_{2}$O$_{3}$ filter showed more than 95$\%$. The removal efficiency of PVDF filter was a little lower than those of other kiters at same pressure(3psi). A ceramic filter showed a higher removal efficiency with other filters, while a little lower flux rate than other filters. Due to inorganic composition, a ceramic filter was highly stable against radio nuclides in comparison with PVDF and PP membrane, which generate H$_{2}$ gas in e-radioactivity atmosphere. Therefore, the adoption of ceramic filter is estimated to be suitable for the real nitration process.

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Estimate of Characteristics and Manufacture of Blood Substitutes (혈액대용물질의 제조 및 특성 평가)

  • Kim, Gi-Beum;Park, Jai-Koan;Kim, Seong-Jong;Kim, Jong-Soo;You, Il-Soo;Kim, Min-Ho;Hong, Chul-Un;Kim, Jin-Shang;Kang, Hyung-Sub
    • Korean Chemical Engineering Research
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    • v.46 no.3
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    • pp.626-632
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    • 2008
  • The purpose of this study was to enhance gas exchange by producing hemosome, a hemoglobin microencapsulated with phospholipid of egg, and perfluorocarbone(PFC) emulsion solution. In the experiment, stable emulsion solution with 437 nm of mean particle size could be produced by Flusol-DA sonication, and shortening of emulsion time could be attained with higher stability as well. $0.8{\mu}m$ sized hemosome could be produced by microencapsulation of hemoglobin with phospholipid extracted from egg yolk. The pattern of oxygen saturation curve of hemosome was S shape, which is similar to that found in normal blood, and $P_{50}$ was measured to be 24 mmHg. The oxygen saturation in the mixed solution of hemosome and blood in 1:4(V/V%) ratio was similar to that of normal blood, and the same result was found in the mixed solution of PFC emulsion and blood in 1:4(V/V%) ratio.