• Title/Summary/Keyword: PEG treatment

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Change in Weight, Moisture Content, and Dimension at the Early Stage of Adsorption-desorption of Polyethylene Glycol-treated Woods (PEG처리재의 초기 흡·탈습과정에서 중량, 함수율 및 치수 변화)

  • Kwon, Gu-Joong;Kim, Nam-Hun;Chun, Kun-Woo
    • Journal of the Korean Wood Science and Technology
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    • v.37 no.6
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    • pp.497-504
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    • 2009
  • The characteristic changes in weight, moisture content, and dimension at the early adsorptiondesorption stage of PEG-treated Korean pine (Pinus koraiensis), Japanese larch (Larix kaempferi), mongolian oak (Quercus mongolica) and sargent cherry (Prunus sargentii) woods were investigated. The wood samples were treated with PEG 1000, 2000 and 4000, and conditioned at the relative 98%, 65% and 20% for humidities of one week. The weight of Korean pine, Japanese larch and sargent cherry woods treated with PEG 1000 and 2000 during the adsorption-desorption was significantly changed, but mongolian oak was slightly changed. Moisture content was highly Moisture content was highly fluctuated by the change of relative humidity in the three species except oak wood. Although the weight of PEG-treated wood; however, changes in dimension could be prevented by PEG treatment in all species tested.

Conservation of Excavated Lacquer-wares for using artificially water-soaked Lacquer-wares (인공수침 칠기를 이용한 고대칠기 보존연구)

  • Kim, Soo-Chul
    • Journal of Conservation Science
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    • v.21
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    • pp.49-58
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    • 2007
  • Among the treatment results of test samples of the antique lacquer-ware, the treatment with PEG#3,350 40% solution displayed excellent effect with low shrinkage ratio; in weight gain the treatment with Sucrose 19%+Glycerin 1%(t-butanol 5% in water) solution showed consistent increase. However during the impregnation process of Sucrose, the weight of the testing samples decreased by dehydration because the inner part of the test samples and the treatment solution showed concentration gradient. Therefore, we concluded longer impregnation period should be necessary to prevent dehydration. Since both higher and lower molecular weight treatment chemicals could penetrate into the wood of the lacquer-ware, air drying and conditioning after impregnation treatment with high concentration chemicals would be possible, as well as vacuum freeze-drying.

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Morphology control in PVDF membranes using PEG/PVP additives and mixed solvents

  • Rajabi, Shima;Khodadadi, Foroogh;Mohammadi, Toraj;Tavakolmoghadam, Maryam;Rekabdar, Fatemeh
    • Membrane and Water Treatment
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    • v.11 no.4
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    • pp.237-245
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    • 2020
  • The effects of the mixed two solvents, Dimethylacetamide (DMAc) and Dimethylformamide (DMF), and Polyethylene glycol (PEG) and Polyvinylpyrrolidone (PVP) as additives on performance of Polyvinylidene fluoride (PVDF) membranes were studied. Initially, PEG200 was used as a primary additive at fixed percentage of 5% wt. PVP was then blended with PEG200 in different concentrations. PVDF and DMAc were used as polymer and solvent in the casting solutions, respectively. To control the diffusion rate of PVP in the presence of PEG200 and PVP blend, mixtures of DMAc and DMF were used as the mixed solvent in the casting solutions. Asymmetric PVDF membranes were prepared via phase inversion process in a water bath and the effects of two additives and two solvents on the membrane morphology, pure water flux (PWF), hydrophilicity and rejection (R) were investigated. Attenuated Total Reflection Fourier Transform Infrared Spectra (ATR-FTIR) analysis was used to show the residual PVP on the surface of the membranes. Atomic Force Microscopy (AFM) was utilized to determine roughness of membrane surface. The use of mixed solvents in the casting solution resulted in reduction of PVP diffusion rate and increment of PEG diffusion rate. Eventually, PWF and R values reduced, while porosity and hydrophilicity increased.

Dehydration and pore swelling effects on the transfer of PEG through NF membranes

  • Escoda, Aurelie;Bouranene, Saliha;Fievet, Patrick;Deon, Sebastien;Szymczyk, Anthony
    • Membrane and Water Treatment
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    • v.4 no.2
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    • pp.127-142
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    • 2013
  • In order to investigate the significance of "salting-out" and "pore swelling" effects on the nanofiltration of neutral solutes, rejection properties of two NF ceramic and polymeric membranes were studied with single polyethyleneglycol (PEG) solution and mixed PEG/inorganic electrolyte solutions. For both membranes, the rejection rate of PEG was found to decrease significantly in the presence of ions. In the case of the ceramic membrane (rigid pores), this phenomenon was imputed to the sole partial dehydration of PEG molecules induced by the surrounding ions. This assumption was confirmed by the lowering of the PEG rejection rates which followed the Hofmeister series. Experimental data were used to compute the resulting decrease in the Stokes radius of PEG molecules in the presence of the various salts. Concerning the polymeric membrane, the decrease in the rejection rate was found to be systematically higher than for the ceramic membrane. The additional decrease was then ascribed to the swelling of the pores. The experimental data of rejection rates were then used to compute the variation in the mean pore radius in the presence of the various salts. The pore swelling phenomenon due to accumulation of counterions inside pores was supported by electrokinetic charge density measurements.

Studies on the Polyethylene Glycol-induced Fusion of Two-cell Mouse Embryo Blastomeres (Polyethylene Glycol 처리에 의한 생쥐 2세포기배의 분할구 융합에 관한 연구)

  • 양부근
    • Korean Journal of Animal Reproduction
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    • v.14 no.2
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    • pp.133-140
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    • 1990
  • This study was conducted to develop a simple and efficient technique for fusing 2-cell mouse embryos to obtain tertraploid embryos. Various concentration of PEG and exposure times were compared in order to determine the best condition for fusion and subsequent of fused embryos. The results obtained were follows ; 1. The incidence of fusion induction treated with 40% PEG(70.8%) and 45%(62.7%) for 60 sec. exposure were higher than those of 40% and 45% PEG for 30 sec., 90 sec., or 120 sec. exposure group. Also, the highest incidence of fusion induction(76.9%) was achieved with 120 sec. exposure at 50% PEG concentration. 2. Fused embryos after PEG treatment were cleavaged 2-to 4-cell, 8-cell, morula and blastocyst at 20-24 hr., 30-34., 44-52 hr., respectively, and were not different from those obtained fleshly. 3. The high proportions of the embryos developed to blastocysts after blastomere fusion with 40% PEG for 60 sec., 45% PEG for 60 sec. and 50% for 120 sec. were 66.7%(42/63), 69.0%(29/42) and 32.0%(16/50), respectively, this trend indicated that the fusion rate was similar to the incidence of fused embryos forming blastocysts. 4. The cell number of blastocyst developed from fused embryos(18.7 2.6) was samller than that of untreated embryos(48.9 1.69)

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Studies on the Dimensional Stabilization of Wood -Especially by the Solution of Different Composition by PEG Molecular Weight- (목재(木材)의 치수 안정화(安定化)에 관(關)한 연구(硏究) -Polyethylene Glycol의 혼합액(混合液)을 중심(中心)으로-)

  • Oh, Joung Soo;Cheon, Cheol
    • Journal of Korean Society of Forest Science
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    • v.76 no.2
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    • pp.119-126
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    • 1987
  • This study was carried out to elucidate the desirable PEG molecular weight and it's blending methods which can promote the dimensional stabilization of Corpus controversa, Quercus variabilis and Prunus sargentii. The results may be summarized as follows: 1. PEG polymer loading in woods was affected by specific gravity of wood. And the PEG polymer loading was satisfactory except in Quercus variabilis, which shows the blending method of PEG V was proper. 2. Bulking coefficiency of PEG V was high in Corpus controversa and Prunus sargentii, and it is necessary to paint or coat water-proofing wood preservative: for high bulking coefficiency of Quercus variabilis. 3. In the treatment of PEG V, the antishrink efficiency of Prunus sargentii was 82.59% and that of Quercus variabilis 62.79%. 4. Dimensional stabilization of hardwoods did not have apparant relation with PEG blending method. 5. Judging from results, PEG-400 and PEG-1000 would be enough for dimensional stabilization of hardwood having high specific gravity if other factors are considered well.

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Conservation Treatment of Mituri (hemp shoes) of the Choseon Dynasty in Sacheon, South Korea (사천 구암 출토 미투리 보존처리)

  • Song, Ji-ae;Jeong, Ah-ruem
    • 보존과학연구
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    • s.34
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    • pp.50-61
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    • 2013
  • The Grave encapsulated by lime soil mixture were excavated with clothing and hemp shoes from the Choseon Dynasty in Gooam, Sacheon. Hemp shoes have wood in the center and their surroundings were made of complex materials including herbaceous ones but the front part was lost or became very fragile. We analyzed the hemp shoes and pre-test of consolidant for conservation treatment of hemp shoes. As a result of analyzing, three kinds of plants were identified. For hemp shoes, Oryza spp, hemp, and one kind of dicotyledones were used and it was analyzed that fabrics attached to the back of Dogaengi was cotton. Conservation methods for pre-test of consolidant, Polyethylene Glycol, Paraloid-B72, Dammar gum, Methyl Cellulose and Silicone resin was selected. The solution was sprayed twice in a 24-hour duration. Properties of consolidant was measured; color difference, glossiness difference, folding streangth and tensile streangth. By comparing the results, PEG was confirmed to the most suitable as consolidant. For the conservation treatment, cleaning and strengthening was conducted. For strengthening treatment, PEG 4000 was selected given that the shoes were made of complex materials. The PEG impregnation method was applied with the PEG 4000 concentration gradually changing from 5% to 80% for reinforcement. Then humidity- controlled drying in order to avoid any rapid environment change.

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Cervical Cancer Gene Therapy by Gene Loaded PEG-PLA Nanomedicine

  • Liu, Bo;Han, Shu-Mei;Tang, Xiao-Yong;Han, Li;Li, Chang-Zhong
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.12
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    • pp.4915-4918
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    • 2014
  • Background and Aims: Advances in the treatment of cervical cancer over the last decade have predominantly involved the development of genes directed at molecular targets. Gene therapy is recognized to be a novel method for the treatment of cervical cancer. Genes can be administered into target cells via nanocarriers. This study aimed to develop systemically administrable nano-vectors. Floate (Fa) containing gene loaded nanoparticles (NPs) could target HeLa human cervical cancer cells through combination with receptors on the cells to increase the nuclear uptake of genetic materials. Methods: Fa was linked onto Poly (ethylene glycol)-b-poly (D, L-lactide) (PEG-PLA) to form Fa-PEG-PLA, and the resulting material was used to load plasmids of enhanced green fluorescence protein (pEGFP) to obtain gene loaded nanoparticles (Fa-NPs/DNA). Physical-chemical characteristics, in vitro release and cytotoxicity of Fa-NPs/DNA were evaluated. The in vitro transfection efficiency of Fa-NPs/DNA was evaluated in HeLa cells and human umbilical vein endothelial cells (HUVEC). PEG-PLA without Fa was used to load pEGFP from NPs/DNA as a control. Results: Fa-NPs/DNA has a particle size of 183 nm and a gene loading quantity of 92%. After 72h of transfection, Fa-NPs/DNA displayed over 20% higher transfection efficiency than NPs/DNA and 40% higher than naked DNA in HeLa cells. However, in HUVECs, no significant difference appeared between Fa-NPs/DNA and NPs/DNA. Conclusions: Fa-PEG-PLA NPs could function as excellent materials for gene loading. This nano-approach could be used as tumor cell targeted medicine for the treatment of cervical cancer.

Laxative Choice and Treatment Outcomes in Childhood Constipation: Clinical Data in a Longitudinal Retrospective Study

  • Chanpong, Atchariya;Osatakul, Seksit
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.21 no.2
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    • pp.101-110
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    • 2018
  • Purpose: Functional constipation (FC) is a common gastrointestinal (GI) problem affecting children's well-being and quality of life. Although polyethylene glycol (PEG) is recommended as the first line therapy, it is not always applicable in lower socioeconomic populations. Hence, this study aimed to compare clinical courses of FC in children treated with different medications in order to identify prognostic factors related to treatment outcomes. Methods: We reviewed the medical records of patients aged ${\leq}15$ years diagnosed with FC according to the Rome IV criteria from 2007 to 2015 at the GI clinic, Songklanagarind Hospital. Baseline characteristic, medical history, and treatment outcomes were collected at first and subsequent visits. Results: Exactly104 patients (median age at diagnosis, 2.8 years) were diagnosed with FC. The number of follow-up visits per patient ranged from 1 to 35. The median duration of follow-up was 18.0 months (range, 6.0-84.2 months). PEG was given to 21% of patients. During the follow up period, 76% of patients experienced first recovery with a median time to recovery of 9.8 months. There were no significant differences in time until first recovery and relapse between patients who received and those who did not receive PEG (p=0.99 and 0.06, respectively). Age >6 years, normal defecation frequency, no history of cow's milk protein allergy, and use of laxatives were associated with successful outcomes. Conclusion: Treatment outcomes between patients who had and never had PEG demonstrated no significant difference in our study. Hence, current practices in laxative prescriptive patterns may be effective.

Considerations in the Design of the Preclinical Safety Program for PegIntron

  • Davis, Thomas
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2003.10b
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    • pp.87-88
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    • 2003
  • PegIntron is the pegylated form of human recombinant interferon alfa-2b (IFN${\alpha}$2b). IFN ${\alpha}$2b, known as Intron A, has been in approved clinical use since the 1980's for various cancer indications, and for the treatment of Hepatitis C. In the mid 1990's, several clinical investigators reported that combination therapy with ribavirin and Intron A dramatically increased the therapeutic efficacy for treatment of Hepatitis C.(omitted)

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