• Title/Summary/Keyword: PEG aqueous solution

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Estimation of dimensional stability of woods with time by Polyethylene glycol treatment (Polyethylene glycol처리과정 중 목재 치수안정성의 경시적 평가)

  • 권구중;김남훈
    • Journal of the Korea Furniture Society
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    • v.13 no.1
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    • pp.2-8
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    • 2002
  • This study was carried out to investigate the reasonable condition for better dimensional stability in woods by polyethylene glycol(PEG) treatment. Eight species grown in Kangwon-do were used for this study. Three species of softwoods(Pinus densiflora, Pinus koraiensis, Larix kaempferi) and two species of hardwoods(Prunus sargentii, Populus tomentiglandulosa) treated with 30% aqueous solution of PEG 1000 showed good dimensional stability under the treatment for 1 day. The dimensional stability of Betula davurica, Quercus mongolica and Quercus variabilis woods increased with increasing treatment time. From the above results, it was concluded that PEG penetration and dimensional stability were affected by characteristics of wood species such as density and structure.

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Effects of Salts on the Partition of Proteins in Poly (ethylene glycol)-Dextran Aqueous Two Phase System (Poly(ethylene glycol)-dextran 수용액 2상계에서 단백질 분획계수에 미치는 금속염의 효과)

  • Lee, Sam-Pin;Lee, Cherl-Ho
    • Korean Journal of Food Science and Technology
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    • v.19 no.2
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    • pp.146-150
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    • 1987
  • The effects of pH and added salts on the partition coefficients of proteins in a polyethylene glycol)-dextran aqueous two-phase system were investigated. The partition coefficients attained the lowest value at the isoelectric point of proteins in an equal volume aqueous two-phase system containing 5% PEG and 9.5% dextran in 5 mM phosphate buffer solution. The coefficients increased dramatically at pH 11; BSA which had highest effective hydrophobicity marked 50-fold increase, while ${\beta}-lactoglobulin$ and ovalbumin which had low hydrophobicity 10-fold increase, respectively. The effect of added salts varied with the pH. The partition coefficient increased by the addition of salt at pH 3.0 but decreased drastically at pH 7.0. The partition coefficient increased in the order of added Li < Na < K at pH 3.0 and decreased in the order of added Li < Na < K at pH 11.0.

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Design and Pharmaceutical Evaluation of Biphenyl Dimethyl Dicarboxylate Elastic Capsules (비페닐디메칠디카르복실레이트 연질캅셀제의 설계 및 제제학적 평가)

  • 전인구;곽혜선;문지현
    • Biomolecules & Therapeutics
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    • v.4 no.4
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    • pp.419-427
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    • 1996
  • To solubilize practically insoluble biphenyl dimethyl dicarboxylate (DDB), which has been used for the treatment of chronic hepatitis as tablets or hard capsules, the solubilities of DDB in various hydrophilic, oily and hydrocarbon vehicles, and aqueous surfactant solutions were measured by high performance liquid chromatography. It was found that, among the vehicles studied, polyethylene glycol (PEG) 300 revealed the best solvency, and the solubility reached 17.6 mg/ml at 37$^{\circ}C$. The addition of glycyrrhizic acid ammonium salt (GAA) to DDB-PEG 300 solution (5-20 mg/g) inhibited the formation of precipitates, and at the concentration of 10 mg/g, any precipitaction was not observed even after 2 years at 4$^{\circ}C$. Furthermore, GAA markedly enhanced the permeation of DDB through the rabbit duodenal mucosa in a concentration dependent manner. The addition of copolyvidone (ca. 1.0%) to DDB-GAA-PEG 300 system (1 : 0.5 97.5 w/w) was most effective in preventing the considerable precipitation of DDB-PEG 300 solution (7.5 mg/750 mg) when mixed with water of 300-900 ml at 37$^{\circ}C$. GAA showed a synergistic effect in the prevention of precipitate formation. This finding suggests that this DDB formulation may form less precipitation when DDB soft capsules disintegrate and diffuse into the gastrointestinal fluid, resulting in improving the bioavailability Dissolution rate of DDB (7.5 mg) from sort elastic capsules of DDB-GAA-PEG 300 system was rapid. The supersaturation state was maintained for 2 hr at the concentration of 7.35$\pm$3.3 mg in 900 ml of water without precipitation. The total amount of DDB dissolved from this new formulation was 5.3 and 6.1 times higher, when compared to marketed DDB tablets (25 mg) and capsules (7.5 mg), respectively.

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Gd$_2O_3$:Eu phosphor particles with spherical and filled morphology

  • Roh, Hyun-Sook;Kang, Yun-Chan;Park, Hee-Dong;Park, Seung-Bin
    • 한국정보디스플레이학회:학술대회논문집
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    • 2002.08a
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    • pp.253-256
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    • 2002
  • $Gd_2O_3$:Eu phosphor particles were prepared by largescale ultrasonic spray pyrolysis process. The morphological control of $Gd_2O_3$:Eu particles in spray pyrolysis was performed by adding polymeric precursors into spray solution containing nitrate salts. The effect of composition and amount of polymeric precursors on the morphology, crystallinity, and photoluminescence characteristics of $Gd_2O_3$:Eu particles was investigated. The influence of chain length of PEG on the morphology and photoluminescence intensity was investigated. $Gd_2O_3$:Eu particles prepared from aqueous solution containing no polymeric precursors had a hollow structure and rough surfaces after annealing process. The phosphor particles prepared from solution containing 0.1M CA and 0.lM PEG with high molecular weight as 1,500 had a spherical and filled morphology and the highest photoluminescence intensity, which was 48% higher than that of the $Y_2O_3$:Eu commercial product.

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Preparation TiO$_2$sol using aqueous system and characteristics of its thin film (수용계를 이용한 TiO$_2$Sol의 제조와 박막의 특성)

  • 김성도;조경식;김성진
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.10 no.3
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    • pp.271-277
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    • 2000
  • Transparent $TiO_2$ thin films were prepared by the sol-gel method from titanium alkoxide aqueous solution containing large quantities of water. To prepare the aqueous system sol, the chelate compound solution were prepared from each 1 mole of titanium(IV)iso-propoxide, acetylacetone and 8 moles of isopropyl-alcohol. And then the 50 moles aqueous solution with the 0.02~0.50 moles of HCI for sol stability and the 0.3 mole of polyethylene glycol for coating adhesion were precisely dropped on the chelate compound solution. $TiO_2$thin films were fabricated by dip coating, drying and heat treatment at $400^{\circ}C$ and their characteristics were investigated by XRD, SEM and UV-visible spectrometer, The neutral sol of composition with TTIP : AcAc : IPA : $H_2O$ : PEG : HCl = 1 : 1 : 8 : 50 : 0.3 : 0.15 (molar ratio) was maintained stable sol condition and without problem for coating more than 30 days. The anatase phase $TiO_2$thin film prepared from 30 times dipping, drying and heat treating showed the flat surface and the fine microstructure of fracture surface with about 2 $\mu\textrm{m}$ thickness. Transparency of these $TiO_2$thin film was 80 % in the visible region.

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Ketoprofen-Polyethylene Glycol Conjugate: Pharmacokinetics. anti-inflammatory and analgesic activity

  • Jang, Mi-Hee;Kim, Soo-Yeon;Jeong, Choon-Sik;Oh, Seaung-Youl
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.410.2-411
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    • 2002
  • Ketoprofen (KP), a potent analgesic and non-steroidal anti-inflammatory drug, has some disadvantages such as gastro-intestinal irritation. short half-life (1.5-4 hour) in plasma and low solubility in aqueous solution. In order to minimize these disadvantages. we have recently prepared a KP prodrug, KP-polyethylene glycol conjugate (KPEG750, PEG Mw=750), and investigated its pharmacokinetic behavior. anti-inflammatory and analgesic effect. (omitted)

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Characterizations and Release Behavior of Poly [(R)-3-hydroxy butyrate]-co-Methoxy Poly(ethylene glycol) with Various Block Ratios

  • Jeong, Kwan-Ho;Kwon, Seung-Ho;Kim, Young-Jin
    • Macromolecular Research
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    • v.16 no.5
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    • pp.418-423
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    • 2008
  • Poly[(R)-3-hydroxy butyrate] (PHB) and methoxy poly(ethylene glycol) (mPEG) were conjugated by the transesterification reaction with tin(II)-ethylhexanoate (Sn(Oct)-II) as a catalyst. Hydrophobic PHB and hydrophilic mPEG formed an amphiphilic block copolymer which was formed with the self-assembled polymeric micelle in aqueous solution. In this study, we tried to determine the optimum ratio of hydrophobic/hydrophilic segments for controlled drug delivery. The particle size and shape of the polymeric micelle were measured by atomic force microscopy (AFM) and transmission electron microscopy (TEM). Their size were 61-102 nm with various block ratios. Griseofulvin was loaded in the polymeric micelle as a hydrophobic model drug. The loading efficiency and release profile were measured by high performance liquid chromatography (HPLC). The model drug in our system was constantly released for 48 h.

A Volatile Organic Compound Sensor Using Porous Co3O4 Spheres

  • Kim, Tae-Hyung;Yoon, Ji-Wook;Lee, Jong-Heun
    • Journal of the Korean Ceramic Society
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    • v.53 no.2
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    • pp.134-138
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    • 2016
  • Porous $Co_3O_4$ spheres with bimodal pore distribution (size: 2-3 nm and ~ 30 nm) were prepared by ultrasonic spray pyrolysis of aqueous droplets containing Co-acetate and polyethylene glycol (PEG), while dense $Co_3O_4$ secondary particles with monomodal pore distribution (size: 2-3 nm) were prepared from the spray solution without PEG. The formation of mesopores (~ 30 nm) was attributed to the decomposition of PEG. The responses of a porous $Co_3O_4$ sensor to various indoor air pollutants such as 5 ppm $C_2H_5OH$, xylene, toluene, benzene, and HCHO at $200^{\circ}C$ were found to be significantly higher than those of a commercial sensor using $Co_3O_4$ and dense $Co_3O_4$ secondary particles. Enhanced gas response of porous $Co_3O_4$ sensor was attributed to high surface area and the effective diffusion of analyte gas through mesopores (~ 30 nm). Highly sensitive porous $Co_3O_4$ sensor can be used to monitor various indoor air pollutants.

Studies on the Compatability of the blend of PVA and Methyl cellulose (PVA/메틸셀루로스 블랜드의 상용성에 관한 연구)

  • Park, Jun-Seo;Park, Jang-Woo
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.5 no.2
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    • pp.1-8
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    • 1999
  • The state of compatability of poly(vinyl alcohol)(PVA) and methyl cellulose(MC), prepared by an aqueous solution casting, were investigated over the entire compositions by dynamical mechanical analyzer(DMA) and differential scanning calorimetry(DSC). The glass transition temperatures of the blends, estimated by DMA, indicate that the blends of PVA and MC showed a definite degree of partial miscibility by showing two glass transition temperatures below 80 wt % MC contents in the blends and one glass transition temperature above 80 wt % of MC contents. The DSC results show a depression of melting point and crystallization temperature of PVA in the blends containing more than 80 wt % MC. This indicates that a considerable compatibility in the blend above 80 wt % MC contents may be attribute to the presence of interaction of hydroxyl groups of component polymers through hydrogen bonding. The DMA study of the effect of plasticizer on the polymers showed that water was a good plasticizer for PVA and PEG400 for MC. The addition of water and PEG400 in the blends showed a synergic plasticizing effect on these blends, which resulted in the large extent of the improvement of the compatibility. The elongation of PVA, MC and blonds was found to increase with addition of PEG400 in the blends, but the tensile strength to decrease with addition of plasticizer.

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Varietal Responses of Soybean Germination and Seedling Elongation to Temperature and Polyethylene Glycol Solution (온도와 PEG에 대한 대두품종의 발아 및 묘신장 반응)

  • Seong, Rak-Chun;Chung, Hae-Joon;Hong, Eun-Hi
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.33 no.1
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    • pp.31-37
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    • 1988
  • Germination and seedling elongation of soybeans [Glycine max. (L.) Merr., cults. Bangsakong, Hill, Paldalkong, Danyupkong, Baegwun-kong. Kwangkyokong, Changyupkong and Hwangkeumkong] were measured at two temperatures (15 and 30$^{\circ}C$) and four polyethylene glycol 10,000 (PEG) solutions (0, 20, 30 and 35g/100g-H$_2$O). Adjustments of PEG solution were based on water potentials of 0.0, -0.5, -1.1 and -1.5 MPa at room temperature. Observations were made at 3, 6, 9 and 12 days for 15$^{\circ}C$ and 1, 2, 3 and 4 days for 30$^{\circ}C$. Fifteen seeds of each cultivar were placed on Whatman No. 1 (9cm) filter paper in plastic pertridishes, and adjusted to 15 ml of the proper PEG solution supplemented with 0.2 percent thiram using automatic syringe. The dishes were covered with cap. The seeds were germinated at a continuous temperature of 15 or 30$^{\circ}C$ under dark conditions for programmed period. Seedling moisture content and seedling length of eight soybean cultivars decreased as PEG concentration increased both at 15 and 30$^{\circ}C$. Cultivar differences in seedling moisture content and seedling length were found among eight soybean cultivars at temperatures of 15 and 30$^{\circ}C$. Larger sized cultivar absorbed more moisture than samller sized cultivar. However, reverse results were obtained on the seedling moisture content of each of eight soybean cultivars. Cultiver Hill and Paldalkong showed greater seedling length than the other six cultivars from 20 to 30g/100g water of PEG concentrations both at 15 and 30$^{\circ}C$. The results of this study indicated that germination test of soybean seeds in aqueous solutions of PEG has potential for screening soybean cultivars for improved emergence during moisture stress.

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