• 대한화학회지
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• 제53권4호
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• pp.415-421
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• 2009

수용액에서 다양한 알데히드 5, 5-dimethyl-1, 3-cyclohexanedione을 이용한 1, 8-Dioxo-octahydroxanthene 유도체의 편리하고 실용적인 합성이 촉매인 폴리에틸렌 글리콜(PEG)하에서 성공적으로 수행되었다. 간단한 work-up, 깨끗한 생성물, 높은 수율, 친환경적인 용매인 물의 사용은 이 방법의 특색이다.

• Journal of Pharmaceutical Investigation
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• 제24권4호
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• pp.257-263
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• 1994

The interpenetrating polymer networks (IPNs) of polyacrylic acid (PAA)-polyethylene glycol (PEG) were synthesized via crosslinking of PEG and simultaneous free radical polymerization of PAA. The equilibrium swelling of the IPNs matrices, ranged from 40% to 95%, was varied to a great extent as compared with PAA homopolymer due to the interpolymer interaction between PAA and PEG. The drug release kinetics of drug loaded matrices was significantly affected by the charge of drugs as well as interpolymer complexation.

• 한국가구학회지
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• 제13권1호
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• pp.2-8
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• 2002

This study was carried out to investigate the reasonable condition for better dimensional stability in woods by polyethylene glycol(PEG) treatment. Eight species grown in Kangwon-do were used for this study. Three species of softwoods(Pinus densiflora, Pinus koraiensis, Larix kaempferi) and two species of hardwoods(Prunus sargentii, Populus tomentiglandulosa) treated with 30% aqueous solution of PEG 1000 showed good dimensional stability under the treatment for 1 day. The dimensional stability of Betula davurica, Quercus mongolica and Quercus variabilis woods increased with increasing treatment time. From the above results, it was concluded that PEG penetration and dimensional stability were affected by characteristics of wood species such as density and structure.

• Journal of Pharmaceutical Investigation
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• 제25권4호
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• pp.313-322
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• 1995

The covalent conjugation of human recombinant superoxide dismutase (hrSOD) with trichloros-triazine activated polyethylene glycol (PEG) 5000 formed soluble conjugates with molecular weight of 92KD, which retained $90{\sim}98%$ of original activity with a markedly prolonged plasma half-life of enzyme activity. The effect of hrSOD-PEG conjugates on acetaminophen (ACP)-induced hepatotoxicity was tested in male rats which were pretreated with 3-methylcholanthrene. HrSOD-PEG conjugates inhibited the hepatotoxicity produced by ACP, on the other hand, native hrSOD had no protective effect. The above results indicated that oxygen radicals might participate in the mechanism of the ACP-induced hepatotoxicity and that polymer conjugated-protein drugs with prolonged half-lives could be employed as an effective therapeutic agent.

• 한국염색가공학회지
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• 제30권2호
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• pp.90-97
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• 2018

Hydrophilic reactive hot-melt polyurethane adhesive(HRHA) using a hydrophilic polyol having different molecular weight and NCO index was synthesized. This HRHA was synthesized using Polyethylene glycol(PEG) as a hydrophilic polyol, Polypropylene glycol(PPG) and Polycaprolactone diol(PCL) as hydrophobic polyols, and Methylene diphenyl diisocyanate(MDI) as an isocyanate. The changes in IR spectrum, viscosity and thermal properties of HRHA with different PEG molecular weights and NCO index were investigated, and the tensile strength and elongation of the HRHA casting film and the peel strength, moisture permeability and water pressure of the HRHA coated fabric were confirmed. In this experiment, as the molecular weight of PEG and NCO index increased, the adhesive strength, tensile strength, elongation and moisture permeability was increased but viscosity and Tg was decreased.

• 한국결정성장학회지
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• 제32권3호
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• pp.107-114
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• 2022

Carboxymethyl cellulose/poly(ethylene glycol) (CMC/PEG) hydrogels crosslinked with citric acid (CA) are synthesized to evaluate the effect of CMC molecular weight (Mw), PEG and CA concentration on the optical property, swelling rate (SR), degradation rate (DR), and cytotoxicity and cell proliferation of hydrogels. For crosslinked CMC/PEG hydrogels, the FT-IR peak intensity associated with hydroxyl groups decreases due to PEG intercalation (esterification crosslinking) between CMC chains in a similar manner as the concentration of CA crosslinker increases. Crosslinked CMC (Mw = 90,000)/PEG hydrogels with 10 % CA dissolve regardless of PEG content. However, the SR of the CMC (Mw = 250,000)/PEG hydrogels decrease from 4923 % to 168 % with increasing PEG and CA concentrations from 0 to 20 % and from 0 to 25 %, respectively. As the Mw of CMC increases, the DR of the hydrogel is greatly improved. CMC (Mw = 250,000)/PEG10 hydrogels with 10 % CA exhibit the optimum properties of high absorbing capacity (3,200 %) with moderate DR (54 %), stiffness (1.39 ± 0.19 GPa), and cell viability (94.8 ± 1.3 %). CA-crosslinked CMC/PEG hydrogels are highly suitable for wound dressing or personal care applications due to their non-toxicity, good cell proliferation, SR, and mechanical properties.

• 한국의류학회지
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• 제20권6호
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• pp.992-1001
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• 1996

The binding of polyethylene glycol (PEG, average molecular weight 600) to cotton fabrics was achieved by using pad-dry-cure process in the presence of citric acid, MgCl3·6H3O, DMDHEU, and TEAHCL. Treated fabrics were dyed with direct, acid, and basic dye. Wrinkle recovery angles, durable press rate, wettability, dyeability and color fastness to washing of all treated cottons were evaluated. The results of this study were as follows: 1. The wrinkle resistance of the PEG treated cottons was increased by increasing PEG and DMDHEU concentration. 2. The wettability of the PEG treated cottons was decreased by increasing PEG and DMDHEU concentration, increased by increasing TEAHCL concentration. 3. PEG/DMDHEU/TEAHCL treated cottons had greater affinity on direct, acid, and basic dye than untreated cottons, and dyeability of the modified cottons was improved compare to untreated fabrics. 4. Color fastness to washing of the PEG/DMDHEU/TEAHCL treated cottons was good except for the wash fastness of the direct dye.

• Journal of Pharmaceutical Investigation
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• 제20권1호
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• pp.13-18
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• 1990

Hydrocortisone (HC) sustained-release suppositories were prepared by using a solid matrix of methacrylic acid-methacrylic acid methyl ester copolymer $(Eudragit\;L_{100}^{R}:\;EL)$ as a poorly water soluble carrier and polyethylene glycole 1540 (PEG) as an water soluble carrier. HC release rate was controlled by complexation with ${\beta}-cyclodextrin$ $({\beta}-CyD)$ which was confirmed by X-ray diffractometry, IR-spectroscopy and differential scanning calorimetry. Release rate of HC from the EL-PEG matrix suppositories decreased with increase of EL contents. The release rale from $HC-{\beta}-CyD$ complex decreased in the following order: $HC-{\beta}-CyD/PEG$ > HC/PEG > $HC-{\beta}-CyD/EL_{10%}-PEG$ > $HC/EL_{10%}-PEG$ > $HC-{\beta}-CyD/EL_{15%}-PEG$ > $HC/EL_{15%}-PEG$ > $HC-{\beta}-CyD/EL_{20%}-PEG$ > $HC/EL_{20%}-PEG$. The crystallinity of HC in polymer matrix was identified using X-ray diffractometer and the surface of matrix suppositories after release test was examined by scanning electron microscopy. The sustained release of HC from these matrix suppositories was attributed to the network structure of EL.

• 한국약용작물학회지
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• 제26권1호
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• pp.55-63
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• 2018

Background: The present study assessed the response of kenaf (Hibiscus cannabinus L., Jangdae) seed to NaCl and the effects of polyethylene glycol (PEG) on kenaf seed germination and vigor. Methods and Results: Seed germination ranged from 11.3% to 58.8% after 24 hours of immersion in NaCl concentrations from 0% to 0.5%. The priming treatments had lower electrical conductivity (EC) values for the seeds than for the control and a deteriorated palisade layer. Priming in 10% PEG for 48 hours increased the germination upto 96.3% in $H_2O$ solution and 98.8% in 0.3% NaCl solution compared to that of the control (78.8%). Germination synchronization, and shoot and root growth of the primed seeds were greater than those of the control. The $T_{50}$ of the control in $H_2O$ and 0.3% NaCl solution was 22 and 28 times, respectively. After priming, nine times was sufficient to reach $T_{50}$ in both solution. The mean number of days to germination (MDG) decreased from 1.43 days for the control to 0.55 days for 0% PEG in $H_2O$ solution and from 1.57 days for the control to 0.56 days for 0% PEG in 0.3% NaCl solution. The dry weight after the 10% PEG treatment was higher than that of the control. Conclusions: Taken together, 10% PEG treatment for 24 hours is recommended for kenaf seed invigoration before planting.

• 한국균학회지
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• 18권2호
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• pp.77-83
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• 1990

사철느타리버섯과 느타리버섯의 영양요구주로 원형질체 융합과정을 관찰하고, 융합에 영향을 미치는 여러 가지 요인을 분석한 결과는 다음과 같다. 원형질체에 polyethylene glycol을 혼합하였을 때 원형질체는 서로 응집되어 원형질막의 접착이 이루어졌으며, 0.6 M sucrose로 PEG를 제거한 후에 두 개 또는 다수의 원형질체가 융합되었다. 원형질체 융합에 크게 영향을 주는 요인은 PEG 농도, pH, 삼투압조정제였으며 원형질체의 농도, PEG 흔합시간, 원형질체 배양온도 및 시간, PEG 분자량, $CA^{2+}$, glycine도 영향을 주었다. 가장 알맞는 조건을 pH 8.0으로 조절된 30% PEG 8000으로 원형질체에 혼합하여 $30^{\circ}C$에서 10분간 배양하고 0.6 M sucrose에 현탁하여 동일한 삼투압조정제가 첨가된 배지에서 배양될 때 가장 많은 융합주를 획득할 수 있었다.