Journal of Pharmaceutical Investigation
- Volume 25 Issue 4
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- Pages.313-322
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- 1995
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
The Effect of Human Recombinant Superoxide Dismutase Conjugated with Polyethylene Glycol on the Hepatic Toxicity of Acetaminophen
HrSOD-폴리에칠렌 접합체의 아세트아미노펜 간독성에 미치는 영향
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Yong, Chul-Soon
(College of Pharmacology, Yeungnam University) ;
- Park, Kyong-Ah (College of Pharmacology, Yeungnam University) ;
- Oh, Doo-Man (College of Pharmacology, Catholic University of Taegu-Hyosung)
- Published : 1995.12.20
Abstract
The covalent conjugation of human recombinant superoxide dismutase (hrSOD) with trichloros-triazine activated polyethylene glycol (PEG) 5000 formed soluble conjugates with molecular weight of 92KD, which retained
Keywords
- Human recombinant superoxide dismutase;
- Polyethylene glycol;
- Hepatotoxicity;
- Acetaminophen;
- Oxygen radicals