• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.43 no.8
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• pp.712-721
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• 2015

Pulse Detonation Engine (PDE) has been considered as a future propulsion system for broad range of operation and higher thermal efficiency. Various subsystem technologies have been studied for more than decade to improve the performance of the potential system. New valve systems has been developed for the stable operation at high frequency including inflow-driven valve, rotary valve and valveless system. To foster the detonation initiation with a little ignition energy, plasma ignition method and DDT (deflagration to detonation transition) acceleration method such as swept ramp mechanism have been studied. Fluidic nozzle system and other nozzle system are the ongoing research topics to maximize the propulsion performance of the PDE. Present paper introduces the state of the art of PDE subsystem technologies developed in recent years.

• Proceedings of the Ginseng society Conference
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• 1998.06a
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• pp.216-223
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• 1998

Cyclic nucleotide phosphodiesterases (PDEs) represent the unique enzymatic system degrddinf cAMP and cGMP which play a major role in the regulation of cell physiology. To investigate a possible molecular mechanism of ginsenosides, their activities were evaluated on PDEs which are recently described is new therapeutic targets. PDEs are classified into 7 families according to their genes (PDEI to PDE7) and are differently distributed in tissues. The IC50 values of ginsenosides were determined on PDEI to PDE 5 chromatographically isolatetl from bovine aorta. The results show that total ginseng saponin extract preferentially inhibits PDE 1 and PDE4 at concentrations nearby 200 ug/ml. Protopanaxadiol (PPD) fraction acts preferentially on PDE4 with and IC50 value of 100 nlml and inhibits also PDEI and PDE5 at 14 to 2 fold higher concentrations, respectively. Protopanaxatriol (PPT) fraction preferentially inhibits PDE 1 with and IC50 value of 170 ug/ml. Compound Rgl, originated from PPT fraction, and RC3 (5) represent the most active compounds towards PDE 1 with IC50 values around 80 UM. However Rg3 (R), epimer of Rgl (5) has no effect on the various PDEs tested, excepted on PDE3 rich is sligthly sensitive Compound Rbl, originated from PPD, acts on both PDEI and PDE4. It if two fold less active than Rgl and Rg3 (5) on PDEI. Taken together, these results mainly suggest that PDEI and PDE4 inhibitions could be a molecular mechanism which would participate in ginsenoside mechanisms, especially the effect of PPD on blood vessel and on CNS.

• Journal of the Korean Mathematical Society
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• v.40 no.4
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• pp.695-708
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• 2003

We study the existence of solutions for overdetermined PDE systems that admit prolongation to a complete system. We reduce the problem to a Pfaffian system on a submanifold of the jet space of unknown functions and then express the integrability conditions in terms of the coefficients of the original system. As possible applications we present some local problems in CR geometry: determining the CR embeddibility into spheres and the existence of infinitesimal CR automorphisms.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.03a
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• pp.419-426
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• 2008

As pulse detonation engine(PDE) does not need compression mechanisms such as compressors because self-sustained detonation waves are able to compress propellant gases by their incident shock waves, the PDE can have a simple straight-tube structure. In this study, we propose an autonomous driving valve system of the PDE, which fill premixed gases into the PDE tubes at high frequency with high mass flow rate. The proposed valve is composed of only three parts: a piston, a cylinder, and a spring. This valve system can produce intermittent flow at high mass flow rate, and also can keep stable reciprocal motion by using the propellant-gas enthalpy. When the cylinder content product is assumed to be constant, experimental results of the mass flow rate were approximately equal to the calculation model. We confirmed the autonomous driving valve performance by experiments, and concluded that this extremely simple valve with no electrical power and controller can be used as the PDE propellant supply system.

• Korean Journal of Veterinary Research
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• v.43 no.4
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• pp.615-624
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• 2003

Vascular smooth muscle relaxation is modulated by an increase in cGMP subsequent to nitric oxide (NO) production by endothelial cells. The effects of cAMP and cGMP phosphodiesterase (PDE) inhibitors were investigated in phenylephrine-precontracted rat aorta rings by using the specific inhibitors of PDE I, III, IV and V as relaxing agents (calmodulin-activated PDE inhibitors, IBMX and $W_7$, type I; cAMP-specific PDE inhibitors, milrinone, type IV; Ro 20-1724, type III and cGMP-specific PDE inhibitor, zaprinast, type V). All the PDE inhibitors produced a concentration-dependent relaxation in the ring with intact endothelium (+E). Except for milrinone, all the PDE inhibitors-induced relaxations were inhibited by removal of extracellular $Ca^{2+}$, $N^G$-nitro-L-arginine, $N^G$-nitro-L-arginine methyl ester, methylene blue (MS) or nifedipine. The specific PDE I and PDE IV inhibitors both produced endothelium-independent relaxations which were inhibited by MS in -E rings. However, zaprinast had no effect in -E rings. Except for milrinone, sodium nitroprusside (a NO donor)-induced relaxation was significantly augmented by all PDE inhibitors in +E rings. The results suggest that I) the vasorelaxant properties of IBMX, $W_7$, Ro 20-1724 and zaprinast are dependent on endothelium or on interaction with $Ca^{2+}$ regulation, 2) each PDE is differently distributed in vascular tissues (endothelial and smooth muscle cells), 3) the vasodilations of PDE inhibitors are due to the increase of cAMP and cGMP formation through inhibition of cAMP- and cGMP-PDE and 4) the vasodilation action of milrinone does not involve in endothelial-cyclic nucleotide system.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2004.03a
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• pp.506-512
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• 2004

We analytically estimated the propulsive performance of pulse detonation engines (PDEs) in three cases, which were (1) a fully-fueled simplified PDE, (2) a partially-fueled simplified PDE, and (3) a PDE optimized as a system. The results of the model analyses in the cases of (1) and (2) were in good agreement with published experimental data which were obtained by using simplified PDEs. The comparison between the results of the analyses of simplified PDEs and those of optimized PDE systems showed that specific impulse would become higher by about 10-20% due to PDE-system optimization.

• 제어로봇시스템학회:학술대회논문집
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• 2002.10a
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• pp.46.3-46
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• 2002

Most of the process control algorithms in practice are based on the finite dimensional control theory. However, many chemical processes are described by partial differential equations (PDE's) and are infinite dimensional in nature due to spatial variation. Especially when the convection is dominant and thus diffusion can be ignored, chemical processes that are described by a system of first order hyperbolic PDE's. Such processes include tubular reactors, fixed bed reactors and pressure swinging adsorption. Conventionally such infinite dimensional systems described by PDE's are controlled by finite dimensional controllers that are designed through finite dimensional reduction of the process m...

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2004.03a
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• pp.205-210
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• 2004

The pulse detonation engine (PDE) has recently expected as a new aerospace propulsion system. The PDE system has high thermal efficiency because of its constant-volume combustion and its simple tube structure. We measured thrust of single-tube pulse detonation rocket (PDR) by two methods using the PDR-Engineering Model (full scale model) for ground testing. The first involved measuring the displacement of the PDR-EM by laser displacement meter, and the second involved measuring the time-averaged thrust by combining a load cell and a spring-damper system. From these two measurements, we obtained 130.1 N of time-averaged thrust, which corresponds to 321.2 sec of effective specific impulse (ISP). As well, we measured the heat flux in the wall of PDE tubes. The heat flux was approximately 400 ㎾/$m^2$. We constructed the PDR-Flight Mode] (PDR-FM). In the vertical flight test in a laboratory, the PDR-FM was flying and keeping its altitude almost constant during 0.3 sec.

• Archives of Pharmacal Research
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• v.23 no.1
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• pp.66-71
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• 2000

Peonjahwan, an oriental traditional medicine composed of crude herbal drugs and animal tissues is bitter and poorly water-soluble. To mask the bitterness of peonjahwan and enhance the release of bilirubin, one of the crude active ingredients of peonjahwan, peonja dry elixir (PDE), was prepared using a spray-dryer after extracting the crude materials in ethanol-water solution. coated peonja dry elixir (CPDE) was then prepared by coating the PDE with Eudragit acrylic resin. Panel assessed bitterness and release test of bilirubin from PDE and CPDE were carried out and compared with peonjahwan alone. PDE was found to have little effect upon the reduction of the bitterness of peonjahwan. However, the bitterness of CPDE was found to reduce to 1/4 of that of peonjahwan due to the encapsulation of crude active ingredients by the dextrin and Eudragit shell (P<0.05). The release rate of bilirubin from PDE and CPDE for 60 min increased about 3.5- and 2.5-fold, respectively, compared to peonjahwan at pH 1.2. It is concluded that CPDE, which masked the bitterness of peonjahwan and enhanced the release of bilirubin, is a preferable delivery system for peonjahwan.

• Transactions of the Korean Society of Automotive Engineers
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• v.22 no.4
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• pp.20-29
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• 2014

This research aims to study the new paradigm of NDE measurement which allows the identification of defect locations and sizes of a certain structure by measuring its surface temperature after applying heat. STS which has a certain defect is applied by the heat of 70000W by a heater. Its difference of STS surface temperature is measured by using Infrared thermography. The estimated result of STS experiment and that of theoretical analysis of Flex-PDE are compared and analyzed to diagnose STS defect. Moreover, this study can save time and money and improve accuracy in contrast to the existing ultrasonic NDE experiment. In addition, the new paradigm of NDT/NDE by reverse-engineering will be valid if the data of thermal analysis and temperature distribution from the specifications of many materials is accumulated and verified.