• 한국광학회지
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• 제11권3호
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• pp.206-209
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• 2000

DWDM 시스템에서 외부광변조기와 함께 중장거리 전송을 위한 광원으로 사용이 가능한 파장안정화 고출력 CW DFB 레리저 모듈을 셀계 및 제작하였다. 얇은 두께의 soild etalon과 PD array를 사용하여 단순하고 compact한 파장모니터 기능을 광원 모듈에 내장함으로써 DFB LD의 파장 변화를 감지 및 제어 할 수 있도록 하였다. 또한 높은 출력 특성을 가진 DFB LD와 43% 이상의 높은 광결합 효율을 가지는 모듈을 가지는 모듈의 광학적 설계 및 packaging 기술을 활용하여 mA의 CW 전류인가 조건에서 13nW의 고출력특성ㅇ르 가지는 모듈을 제작하여 그 특성을 분석하였다.

• Korean Journal of Radiology
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• 제22권3호
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• pp.366-375
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• 2021

Objective: To evaluate the radiological tumor response patterns and compare the response assessments based on immune-based therapeutics Response Evaluation Criteria in Solid Tumors (iRECIST) and RECIST 1.1 in metastatic clear-cell renal cell carcinoma (mccRCC) patients treated with programmed cell death-1 (PD-1) inhibitors. Materials and Methods: All mccRCC patients treated with PD-1 inhibitors at Henan Cancer Hospital, China, between January 2018 and April 2019, were retrospectively studied. A total of 30 mccRCC patients (20 males and 10 females; mean age, 55.6 years; age range, 37-79 years) were analyzed. The target lesions were quantified on consecutive CT scans during therapy using iRECIST and RECIST 1.1. The tumor growth rate was calculated before and after therapy initiation. The response patterns were analyzed, and the differences in tumor response assessments of the two criteria were compared. The intra- and inter-observer variabilities of iRECIST and RECIST 1.1 were also analyzed. Results: The objective response rate throughout therapy was 50% (95% confidence interval [CI]: 32.1-67.9) based on iRECIST and 30% (95% CI: 13.6-46.4) based on RECIST 1.1. The time-to-progression (TTP) based on iRECIST was longer than that based on RECIST 1.1 (median TTP: not reached vs. 170 days, p = 0.04). iRECIST and RECIST 1.1 were discordant in 8 cases, which were evaluated as immune-unconfirmed PD based on iRECIST and PD based on RECIST 1.1. Six patients (20%, 6/30) had pseudoprogression based on iRECIST, of which four demonstrated early pseudoprogression and two had delayed pseudoprogression. Significant differences in the tumor response assessments based on the two criteria were observed (p < 0.001). No patients demonstrated hyperprogression during the study period. Conclusion: Our study confirmed that the iRECIST criteria are more capable of capturing immune-related atypical responses during immunotherapy, whereas conventional RECIST 1.1 may underestimate the benefit of PD-1 inhibitors. Pseudoprogression is not rare in mccRCC patients during PD-1 inhibitor therapy, and it may last for more than the recommended maximum of 8 weeks, indicating a limitation of the current strategy for immune response monitoring.

• Transactions on Electrical and Electronic Materials
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• 제7권6호
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• pp.313-318
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• 2006

This paper introduces a partial discharge (PD) severity metric, S, based on the evaluation of time-sequence PD data capture and resulting Time-Sequence-Analysis Discharge (TSAD) level distributions. Basically based on an IEC60270 measurement technique, each PD event is time stamped and the discharge level noted. By evaluating the time differences between a previous and subsequent discharge, a 3D plot of time-sequence activity and discharge levels can be produced. From these parameters a measurement of severity, which takes into account dynamic or instantaneous variations in both the time of occurrence and the level of discharge, rather than using standard repetition rate techniques, can be formulated. The idea is to provide a measure of the severity of PD activity for potentially measuring the state of insulation within an item of plant. This severity measure is evaluated for a simple point-plane geometry in $SF_{6}$ as a function of gap distance and applied high voltage. The results show that as the partial discharge activity increases, the severity measure also increases. The importance of future investigations, quantifications and evaluations of the robustness, sensitivity and importance of such a severity measurement, as well as comparing it with typical repetition rate assessment techniques, and other monitoring techniques, are also very briefly discussed.

• Journal of Ecology and Environment
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• 제43권1호
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• pp.22-30
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• 2019

Background: Piton du Milieu (PdM) impounding reservoir is suspected to be eutrophic based on the elevated level of orthophosphate and nitrate. Water supplies from three adjacent rivers are primarily thought to contribute to the nutrient enrichment of the reservoir. It is also suspected that there is leaching of orthophosphate, nitrate and organic matter into the rivers during rainfall events and also as a result of anthropogenic activities within the catchment area. The aim of this study was to ascertain the impact of nutrient loading on the water quality of PdM water and on the population of freshwater microalgae in the reservoir. The enumeration and identification of algae from PdM were performed by differential interference contrast microscopy. Dissolved oxygen (DO) and pH were determined by electrometric methods, whereas nutrient levels, silica and total organic carbon (TOC) were determined by instrumentation techniques. Results: Annual mean orthophosphate, nitrate and total organic carbon input from the three feeders within the catchment area of PdM reached levels as high as 0.09 mg/L, 0.4 mg/L and 2.62 ppm respectively. Over a 12-month period, mean TOC concentration in the reservoir was 2.32 ppm while the mean algal cell count was 4601 cells/mL. The dominant algal species identified were Oscillatoria, Cyclotella, Navicula and Cosmarium. Conclusion: This study highlights the trophic state of the reservoir water and clearly points to the need for constant monitoring in order to avoid the occurrence of an impending harmful algal bloom.

• 한국철도학회논문집
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• 제20권2호
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• pp.203-209
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• 2017

전력공급의 안정성 및 신뢰도 향상을 위해 각종 전력설비의 예방진단에 관한 연구개발이 활발하다. 가스절연개폐장치와 변압기와 같은 단위 기기의 절연진단기술은 빠르게 발전하고 있으나, 전력케이블에 있어서는 단순히 결함의 유무와 부분방전을 측정할 뿐, 세부적 특성에 대해서는 거의 연구되고 있지 않다. 따라서 본 논문에서는 XLPE 케이블에서 보이드의 크기와 위치에 따른 부분방전 특성과 결함의 위치추정에 관한 연구를 수행하였다. 보이드의 크기 및 위치에 따른 4종의 결함계를 모의하였으며, 부분방전펄스는 주파수 대역 150kHz~30MHz의 고주파변류기로 검출하였다. 실험결과, 도체에 인접한 결함일수록 방전전하량이 크고, 정극성에 비해 부극성의 방전펄스 수가 약 20% 많게 나타났다. 또한 TDR 방법으로 결함위치를 산출하였으며, 50m 케이블에서 1m 이내로 결함의 위치를 추정할 수 있었다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 제36회 하계학술대회 논문집 C
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• pp.2066-2068
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• 2005

We developed an on-line Ultra-high frequency partial discharge monitoring system to prevent a catastrophic failure of gas- insulated switchgears. The system has been tested in the laboratory for detection of various UHF PD signals. We also performed detection sensitivity verification tests and compared them with conventional IEC60270 method.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2003년도 하계학술대회 논문집 C
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• pp.1894-1896
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• 2003

In this paper, a novel monitoring system, data acquisition & diagnosis unit (DADU), for high-voltage rotating machines is proposed. This system monitors the insulation condition, current, voltage, vibration, and temperature of the stator winding by on-line measurements of partial discharge (PD), flux, etc. This helps more efficient operation and maintenance of the rotating machines.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2004년도 추계학술대회 논문집 전기물성,응용부문
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• pp.112-116
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• 2004

On-line monitoring of fault discharge is an important approach for indicating the condition of electrical insulation of stator winding in high voltage motor. In this paper, several key aspects of on-line monitoring system are discussed, involving the characteristics of fault discharge of stator winding in high voltage motor, spectrum analysis of four simulation fault signals, feature extraction of internal fault discharge from apply voltage to breakdown. The study of the partial discharge activities allows to highlight the ageing stage in the winding fault under test. During the life of the winding insulation fault, the shape of PD signal change relating to the ageing stage. The ageing of stator winding insulation fault of high voltage motor is investigated based on the characteristics of partial discharge pulse distribution and statistical parameters, such as maximum, skewness and kurtosis using discrete wavelet transform coefficients.

• 한국자기공명학회논문지
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• 제7권1호
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• pp.1-15
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• 2003

PURPOSE - To investigate neurometabolism from the brain destructive lesions and striatal putamen-pallidus regions to the clinically worst side in patients with Parkinson's disease after stereotactic functional neurosurgery. METHODS - Using proton magnetic resonance spectroscopy ($^1$H MRS), fifteen patients (7 males and 8 females; mean age 56.5 years; age range 43-67 years) with Parkinson's disease (PD) were studied to measure N-acetylaspartate (NAA), creatine (Cr), choline-containing compounds (Cho) and lactate (Lac) levels on the neurosurgical lesions of thalamus, globus pallidus and striatal putamen-pallidus regions in a brain. RESULTS - Brain destructive lesion and striatal putamen-pallidus region in PD compared with controls were highly and significantly related to NAA/Cho ratios reduction, respectively (P =0.002, P =0.04), but showed no difference from the same regions of PD prior to neurosergery (P =0.06, P =0.77). Increased lactate peaks at 1.3 ppm were present in all the cerebral lesions, and these resonances were confirmed at a long TE =136 ms, indicating that these signals distinguished from lipids. CONCLUSIONS - Our results suggest that NAA/Cho ratios may provide as a neurometabolite marker for neurochemical changes in brain surgical lesion, and the ratios might be related to functional change of neuropathophysiological status in the striatal putamen-pallidus region of PD. Increase of lactate signals, being remarkable in surgical lesions, could be consistent with a common consequence of surgical necrosis. Therefore, MR spectroscopy could be a sensitive diagnostic tool in monitoring neurometabolic changes in PD with neurosurgical treatment.

• 전기학회논문지
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• 제61권7호
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• pp.1056-1060
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• 2012

Online monitoring system is becoming an essential element of railway traction system for utilized to condition based malignance management and various techniques currently employed in railway traction system. Among the various techniques, it is efficient to detect partial discharge signals by electromagnetic wave detection in order to detect insulation fault of rectifier. Although VHF (Very High Frequency), UHF (Ultra High Frequency) sensors were adopted to detect partial discharge of power facilities, due to characteristics of urban railway, excessive noise occurs from 500 MHz to 1.5 GHz on UHF bandwidth. In this paper a new measurement system able to monitoring the conditions of power facilities on DC substation in metro was studied and set up. The system uses UHF sensors to measure the partial discharge of the rectifier due to electric faulting and dielectric breakdown. Comparison and estimation for performance of SHF sensor which had devised to detect partial discharge signal of urban railway rectifier has conducted. In order to estimate performance of SHF sensor, we have compared the sensor with existing UHF sensor on sensitivity upon frequency bandwidth generated by pulse generator, and also we have verified performance of the SHF sensor by detection results of partial discharge signal from urban railway rectifier.