• Title/Summary/Keyword: PD Index

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Pancreaticoduodenectomy with superior mesenteric artery first-approach combined total meso-pancreas excision for periampullary malignancies: A high-volume single-center experience with short-term outcomes

  • Thanh Khiem Nguyen;Ham Hoi Nguyen;Tuan Hiep Luong;Kim Khue Dang;Van Duy Le;Duc Dung Tran;Van Minh Do;Hong Quang Pham;Hoan My Pham;Thi Lan Tran;Cuong Thinh Nguyen;Hong Son Trinh;Yosuke Inoue
    • Annals of Hepato-Biliary-Pancreatic Surgery
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    • v.28 no.1
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    • pp.59-69
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    • 2024
  • Backgrounds/Aims: Pancreaticoduodenectomy (PD) is the only radical treatment for periampullary malignancies. Superior mesenteric artery (SMA) first approach combined with total meso-pancreas (MP) excision was conducted to improve the oncological results. There has not been any previous research of a technique that combines the SMA first approach and total MP excision with a detailed description of the MP macroscopical shape. Methods: We prospectively assessed 77 patients with periampullary malignancies between October 2020 and March 2022 (18 months). All patients had undergone PD with SMA first approach combined total MP excision. The perioperative indications, clinical data, intra-operative index, R0 resection rate of postoperative pathological specimens (especially mesopancreatic margin), postoperative complications, and follow-up results were evaluated. Results: The median operative time was 289.6 min (178-540 min), the median intraoperative blood loss was 209 mL (30-1,600 mL). Microscopically, there were 19 (24.7%) cases with metastatic MP, and five cases (6.5%) with R1-resection of the MP. The number of lymph nodes (LNs) harvested and metastatic LNs were 27.2 (maximum was 74) and 1.8 (maximum was 16), respectively. Some (46.8%) patients had pancreatic fistula, but mostly in grade A, with 7 patients (9.1%) who required re-operations. Some 18.2% of cases developed postoperative refractory diarrhea. The rate of in-hospital mortality was 1.3%. Conclusions: The PD with SMA first approach combined TMpE for periampullary malignancies was effective in achieving superior oncological statistics (rate of MP R0-resection and number of total resected LNs) with non-inferior short-term outcomes. It is necessary to evaluate survival outcomes with long-term follow-up.

Do some patients receive unnecessary parenteral nutrition after pancreatoduodenectomy? Results from an international multicentre study

  • Thomas B. Russell;Peter L. Labib;Paula Murphy;Fabio Ausania;Elizabeth Pando;Keith J. Roberts;Ambareen Kausar;Vasileios K. Mavroeidis;Gabriele Marangoni;Sarah C. Thomasset;Adam E. Frampton;Pavlos Lykoudis;Manuel Maglione;Nassir Alhaboob;Hassaan Bari;Andrew M. Smith;Duncan Spalding;Parthi Srinivasan;Brian R. Davidson;Ricky H. Bhogal;Daniel Croagh;Ismael Dominguez;Rohan Thakkar;Dhanny Gomez;Michael A. Silva;Pierfrancesco Lapolla;Andrea Mingoli;Alberto Porcu;Nehal S. Shah;Zaed Z. R. Hamady;Bilal Al-Sarrieh;Alejandro Serrablo;Somaiah Aroori
    • Annals of Hepato-Biliary-Pancreatic Surgery
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    • v.28 no.1
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    • pp.70-79
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    • 2024
  • Backgrounds/Aims: After pancreatoduodenectomy (PD), an early oral diet is recommended; however, the postoperative nutritional management of PD patients is known to be highly variable, with some centers still routinely providing parenteral nutrition (PN). Some patients who receive PN experience clinically significant complications, underscoring its judicious use. Using a large cohort, this study aimed to determine the proportion of PD patients who received postoperative nutritional support (NS), describe the nature of this support, and investigate whether receiving PN correlated with adverse perioperative outcomes. Methods: Data were extracted from the Recurrence After Whipple's study, a retrospective multicenter study of PD outcomes. Results: In total, 1,323 patients (89%) had data on their postoperative NS status available. Of these, 45% received postoperative NS, which was "enteral only," "parenteral only," and "enteral and parenteral" in 44%, 35%, and 21% of cases, respectively. Body mass index < 18.5 kg/m2 (p = 0.03), absence of preoperative biliary stenting (p = 0.009), and serum albumin < 36 g/L (p = 0.009) all correlated with receiving postoperative NS. Among those who did not develop a serious postoperative complication, i.e., those who had a relatively uneventful recovery, 20% received PN. Conclusions: A considerable number of patients who had an uneventful recovery received PN. PN is not without risk, and should be reserved for those who are unable to take an oral diet. PD patients should undergo pre- and postoperative assessment by nutrition professionals to ensure they are managed appropriately, and to optimize perioperative outcomes.

Clinical comparison of resorbable and nonresorbable Barrier in guided tissue regeneration of human intrabony defects (흡수성 차폐막을 이용한 조직유도재생술의 임상적 효과)

  • Hur, Yin-Shik;Kwon, Young-Hyuk;Lee, Man-Sup;Park, Joon-Bong;Herr, Yeek
    • Journal of Periodontal and Implant Science
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    • v.29 no.1
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    • pp.193-207
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    • 1999
  • The purpose of this study was to compare the clinical results of guided tissue regeneration(GTR) using a resorbable barrier manufactured from an copolymer of polylactic acid (PLA) and polylaetic-glycolic acid(PLGA) with those of nonresorbable ePTFE barrier. Thirty two patients(25 to 59 years old) with one radiographically evident intrabony lesion of probing depth ${\geq}$6mm participated in a 6-month controlled clinical trial. The subjects were randomly divided into three independent groups. The first group(n=8) received a ePTFE barrier. The second group (n=12) received a resorbable PLA/PLGA barrier. The third group (n=12) received a resorbable PLA/PLGA barrier combined with an alloplastic bone graft. Plaque index (PI), gingival index(GI), probing depth(PD), gingival recession, clinical attachment level(CAL), and tooth mobility were recorded prior to surgery and at 3, 6 months postsurgery, Statistical tests used to analyze these data included independent t-test, paired t-test, one-way ANOVA. The results were as follows : 1. Probing depth was significantly reduced in all groups at 3, 6 months postsurgery and there were not significant differences between groups. 2. Clinical attachment level was significantly increased in all groups at 3, 6 months postsurgery and there were not significant differences between groups. 3. There were not significant differences in probing depth, clinical attachment level, gingival recession, tooth mobility between second group (PLA/PLGA barrier) and third group (PLA/PLGA barrier combined with alloplastic bone graft) 4. Tooth mobility was not significantly increased in all groups at 3, 6 months postsurgery and there were not significant differences between groups. In conclusion, PLA/PLGA resorbable barrier has similar clinical potential to eP'IFE barrier in GTR procedure of intrabony pockets under the present protocol.

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Association between periodontal disease and coronary heart disease (치주질환과 관상동맥질환의 관련성에 대한 임상적 연구)

  • Lee, Jun-Ho;Chung, Hyun-Ju;Kim, Ju-Han
    • Journal of Periodontal and Implant Science
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    • v.35 no.1
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    • pp.111-121
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    • 2005
  • Coronary heart disease is the leading cause of mortality in adult population. Whereas the association between periodontal disease and coronary heart disease (CHD) are controversial, recent studies reported the association between periodontal disease and acute myocardial infarction or prognosis of CHD. This study was aimed to investigate the relationship between periodontal disease and angiographically defined CHD, and acute myocardial infarction, and the prognosis of treated CHD. Patients under the age of 60 who had undergone the diagnostic coronary angiography were enrolled in this study, Subjects were classified as positive CHD (+CHD, n=37) with coronary artery stenosis more than 50% in at least one of major epicardial arteries, and negative CHD (-CHD, n=20) without stenosis. After recording the number of missing teeth, periodontal disease status was measured by means of plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), and clinical attachment level (CAL), Positive CHD subjects were classified into acute myocardial infarction group (AMI), and non-AMI with angina pectoris and old myocardial infarction. Six months postoperatively, positive CHD subjects were followed and had undergone the coronary angiography again. Even though there was no significant difference in the periodontal parameters and status between positive CHD and negative CHD, some periodontal parameters, such as mean probing depth and proportion of sites with probing depth greater than 4mm or 6mm were significantly different between AMI and Non-AMI(p<0.05). There was no significant difference in the periodontal parameters according to in angiographically follow-up status. These results indicate that periodontal disease may be associated with the occurrence of acute myocardial infarction.

The Effect of Silicone Toothbrush on Plaque Control and Gingival Inflammation. A Comparative Clinical Study (치태제거 및 치은염증에 대한 실리콘 칫솔의 효과)

  • Chung, Yeh-Jin;;Suh, Jong-Jin;Cho, Kyoo-Sung;Chai, Jung-Kiu;Kim, Chong-Kwan;Choi, Seong-Ho
    • Journal of Periodontal and Implant Science
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    • v.30 no.4
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    • pp.911-923
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    • 2000
  • A comparative clinical study on the ordinary toothbrush($Buttler^{(R)}$, America) and the silicone toothbrush($Jefe^{(R)}$, Korea) was performed. The volunteers who took part in this study were students of Dental college of Yonsei University and patients attending Dental Hospital of Yonsei University. They were classified into two group, control and experimental group. Control group brushed with nylon toothbrush and experimental group did with silicone toothbrush under the researcher's guidances. Volunteers were examined on Plaque Index(PI), Gingival Index(GI), Probing Depth(PD), Bleeding on Probing(BP) and Recession(R) at base line, 1st. week, 2nd. week and 4th. week. According to the results, both group have the tendency of improvement in the degrees of GI, PI and the improvement degree of GI of both group has the significant differences from base line statistically, and there are not statistically significant differences between the silicone and nylon group in respect of PI, GI values. So based on the present study, it could be carefully ascertained that the silicone toothbrush has similar effect with nylon toothbrush in respect of PI and GI. If it is sure that the silicone toothbrush is seldom abrasive and possibly enough to massage the gingiva, this new brush is worth to be recommended by the dentists.

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Periodontal health status, oral microbiome, white-spot lesions and oral health related to quality of life-clear aligners versus fixed appliances: A systematic review, meta-analysis and meta-regression

  • Ana Sandra Llera-Romero;Milagros Adobes-Martin;Jose Enrique Iranzo-Cortes;Jose Maria Montiel-Company;Daniele Garcovich
    • The korean journal of orthodontics
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    • v.53 no.6
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    • pp.374-392
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    • 2023
  • Objective: Assess and evaluate the different indicators of oral health-related quality of life (OHRQoL) among patients treated with clear aligners (CAs) versus those treated with conventional fixed orthodontics (FAs). Methods: An electronic search was performed on the database is Web of Science, Scopus, and Embase databases. Randomized and non-randomized control trials, cross-sectional, prospective cohort and retrospective trials were included. Quality was assessed with risk of bias tool and risk of bias in non-randomised studies. Meta-analyses were performed with random effects models, estimating the standardized and non-standardized mean differences, odds ratio and risk ratio as the measure of effect. The effect on time was determined using a meta-regression model. Results: Thirty one articles were included in the qualitative synthesis and 17 in the meta-analysis. CAs had a significantly lower negative impact on QoL, with an "important" effect size, while the influence of time was not significant. Periodontal indicators plaque index (PI), gingival index (GI), probing depth (PD), and bleeding on probing show significantly better values in patients treated with CAs, with moderate to large effect sizes. PI and GI have a significant tendency to improve over time. In microbiological indicators, CAs present a lower biofilm mass without differences in the percentage of patients with high counts of Streptococcus mutans and Lactobacilli bacteria. The risk of white spot lesion onset is ten times lower in carriers of CAs. Conclusions: Patients wearing CAs show better periodontal indicators, less risk of white spot development, less biofilm mass and a better QoL than patients with FAs.

A Study on Prediction of Propulsive Energy Loss Related to Automatic Steering of Ships in Following Seas (추사피중에서 자동조타로써 항행하는 선박의 추진에너지 손실량 평가에 관한 연구)

  • 이경우;손경호
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 1996.04a
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    • pp.77-92
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    • 1996
  • When an automatic course-keeping is concerned as is quite popular in modern navigation the closed-loop steering system consists of autopilot device power unit (or telemotor unit) steering gear magnetic or gyro compass and ship dynamics. The consideration of irregular disturbances to ship dyanmics and a few non-linear mechanisms involved in the system inevitably or artificially are known to be very important in properly evaluating or analyzing the automatic steering system. In the present study the mathematical model of each element of an automatic steering system is derived which takes account of a fex non-linear mechanisms. PD(Proportional-Derivative) controller and low-pass filter with a weather adjustment are adopted to modelling the characteristics of an autopilot. The calculation method of imposing irregular disturbances to ship dynamics is proposed where irregular disturbances implying irregular wave and the fluctuating component of wind. For he evaluation of automatic steering system of ships in the open seas an important term "performance index" is introduced from the viewpoint of energy saving which derived from the concept of energy loss on ship propulsion. Finally the present methods are applied to two typical types of ship ; an ore carrier and a fishing boat. The various effects of linear and/or non-linear control constants of autopilot on propulsive energy loss are investigated to validate and clarify the present smulation technique.

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Spatial Characteristic Analysis for the Main Production Areas of Vegetables based on Landscape Indices (경관지수를 활용한 채소 주산지 공간적 분포 특성 분석)

  • Bae, Seung-jong;Kim, Dae-Sik;Kim, Soo-Jin;Oh, Yun-Gyeong
    • Journal of Korean Society of Rural Planning
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    • v.23 no.1
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    • pp.135-146
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    • 2017
  • The objective of this study is to accurately understand the spatial distribution characteristics of the main production area for the three vegetable crops such as Chinese cabbage, radish, and hot pepper. We applied the 8 landscape indices such as TA, NP, PD, LPI, LSI, PLADJ, COHESION, and CONNECT to 35 cities and counties using FRAGSTATS. In the case of main production area for Chinese cabbage, six cities and counties in Gangwon province were revealed as a relatively high degree of aggregation by cultivation parcels than other area. In addition, Gangneung city and Hongcheon county have been analyzed to be the most aggregated area in the case of radish and hot pepper, respectively. In the future, the spatial analysis method used in this study would be helpful to develop an effective regional plan of the main production area.

Relationships between MMPI Scales under Defensive Attitude and Safety and Health Indices

  • Kim, Jong Hwan;Jeong, Byung Yong;Park, Myoung Hwan
    • Journal of the Ergonomics Society of Korea
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    • v.35 no.6
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    • pp.611-619
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    • 2016
  • Objective:This study aims to analyze the relationships between personality factors measured by Minnesota Multiphasic Personality Inventory (MMPI) scales and the indices of safety and health in the shipbuilding industry. Background: Many researches reported that there were significant relationships between some MMPI subscales and traffic and industrial accidents. Method: This study analyzes 230 male workers in shipyard for their MMPI scores gathered during recruitment process and their safety and health indices from the performance record during their working period. ${\chi}^2-test$ and one-way ANOVA are used for finding the statistical significance for personality factors. The conventional grouping rule for MMPI scales and other grouping criteria considering the attitude of positive answer for the MMPI test during recruitment process are used for analysis. Results: The Hypomania (Ma) and Psychopathic Deviate (Pd) scales of the MMPI are the main factors related to the safety and health related indices for most grouping rules. Depression (D), Psychasthenia (Pt), Hypochondriasis (Hs), Schizophrenia (Sc), and Masculinity and Femininity (Mf) scales are also related to the safety and health indices. Conclusion and Application: The results can be used for understanding the psychological factors in human behaviors and safety and can help professional personnel take the necessary steps in improving safety on the job and also in providing the effective teaching of safe work methods.

A Study on the Occurrence Pattern of Vacant Spaces as the Decline Index in Old Hillside Residential Area (노후 경사주거지 쇠퇴지표로서의 유휴공간 발생패턴 연구)

  • Jung, In-A;Woo, Shin-Koo
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.34 no.3
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    • pp.93-104
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    • 2018
  • This study is about occurrence pattern of vacant spaces as a urban decline indicator to consider a decline of old hillside residential area from spatial structure perspective. For investigation based upon vacant space and the street structure, this study selects Ami Chojang-dong in Seo-gu, Busan, of which 79.7% of total area is over a gradient of $10^{\circ}$. Focused on relationship between occurrence pattern of vacant spaces and 'vertical alleys(link)' serving as main movement path of local residents in hillside residential area, the length, numbers, slopes, and use characteristic of vertical alleys were analyzed using Arc GIS 9.3 program to classify characteristic zone types of spacial structure in hillside residential area. After the occurrence pattern of vacant space are interpreted in relation with building density, vertical alleys' number length slope, the social and economic issues have been considered as well. After analyzing the occurrence pattern of vacant space, this study argues that the occurrence pattern of vacant space in old hillside residential area is rather affected by street structure system consisting of vertical alleys than the impacts of social economical issues.