• 제목/요약/키워드: PCa

검색결과 2,564건 처리시간 0.029초

제왕절개술후 자가진통법을 이용한 정맥내 Nalbuphine은 경막외 Morphine과 Bupivacaine 혼합제를 대치할 수 있나? (Intravenous Patient-Controlled Analgesia with Nalbuphine: Could be an Alternative to Epidural Patient-Controlled Analgesia with Morphine-Bupivacaine for Pain Relief after Cesarean Delivery?)

  • 이종석;이윤우;윤덕미;남용택;송근호
    • The Korean Journal of Pain
    • /
    • 제10권1호
    • /
    • pp.34-41
    • /
    • 1997
  • Background : Patient-controlled analgesia(PCA) is a safe and effective technique for providing postoperative pain relief. Studies that compare epidural vs intravenous routes of opiate administration show conflicting results. We designed a prospective, randomized, controlled study to evaluate the safety and efficacy of epidural(EPI-PCA) morphine-bupivacaine versus intravenous (IV-PCA) nalbuphine when administered with a PCA system. Methods : Forty healthy women were randomly assigned to receive an epidural bolus of morphine 3 mg and 0.5% bupivacaine 10 ml, followed by a EPI-PCA with 0.01% morphine and 0.143% bupivacane (basal infusion 1 ml/hr, bolus 1 ml, lock-out interval 30 min) or intravenous bolus of nalbuphine 0.1 mg/kg followed by a IV-PCA with nalbuphine(basal infusion 1 mg/hr, bolus 1 ml, lock-out interval 20 min) for pain relief after cesarean delivery. This study was conducted for 2 days after cesarean section to compare the analgesic efficacy, side effects, patient satisfaction either as EPI-PCA or as IV-PCA. Results : EPI-PCA group had significant lower visual analog pain scale(VAS) at immediate postoperative period, whereas no significant difference was observed when pain was assessed at other time sequence. Urinary retention and pruritus were more frequent with EPI-PCA group, although the incidence of other side effects were the same. Conclusions : Although EPI-PCA with morphine-bupivacaine was of significantly lower VAS at immediate postoperative period, IV-PCA with nalbuphine is a safe and effective alternative to EPI-PCA with morphine-bupivacaine for providing pain relief after cesarean delivery. Further studies about IV-PCA with nalbuphine are needed to control the immediate postoperative pain and to further improve effective pain management.

  • PDF

RNA 정량법(定量法)에 관한 연구(硏究) -과염소산(過鹽素酸)농도가 Orcinol 반응(反應)에 미치는 영향(影響)- (A Study on RNA Determination by Ribose Estimation -Condition of Perchloric acid Concentration on the Color generation by Orcinol reaction-)

  • 배무;김병홍
    • 한국식품과학회지
    • /
    • 제3권2호
    • /
    • pp.105-109
    • /
    • 1971
  • 1) 열산처리(熱酸處理)에서 산(酸)의 농도(濃度)는 TCA, PCA 모두 5%이면 충분하다. 2)열산처리시간(熱酸處理時間)은 발색시간(發色時間)을 15분(分)으로 할 때 20이면 충분하다. 3) 20 분간(分間) 열산처리(熱酸處理)하면 발색시간(發色時間)은 15분(分)이면 된다. 4) PCA 농도(濃度)가 5% 이상(以上)에서는 RNA 전처리(前處理)에서는 영향을 미치지 않으나 발색(發色)시킬 때는 영향을 미치므로서 이때 PCA의 농도(濃度)를 일정(一定)하게 해줄 필요(必要)가 있다. 5) 발색(發色)시킬 때 시료(試料) 중(中)에 TCA가 5% 이상(以上) 공존(共存)하면 현탁되어 OD 측정(測定)이 불가능(不可能)하며 PCA처럼 농도차(濃度差)가 색도(色度)에 영향을 미칠 가능성(可能性)이 있으므로 열산처리(熱酸處理)는 TCA보다 PCA를 사용(使用)하는 것이 좋다.

  • PDF

포즈 추정 기반 포즈변화에 강인한 얼굴인식 시스템 설계 : PCA와 RBFNNs 패턴분류기를 이용한 인식성능 비교연구 (Design of Robust Face Recognition System to Pose Variations Based on Pose Estimation : The Comparative Study on the Recognition Performance Using PCA and RBFNNs)

  • 김봉연;김진율;오성권
    • 전기학회논문지
    • /
    • 제64권9호
    • /
    • pp.1347-1355
    • /
    • 2015
  • In this study, we compare the recognition performance using PCA and RBFNNs for introducing robust face recognition system to pose variations based on pose estimation. proposed face recognition system uses Honda/UCSD database for comparing recognition performance. Honda/UCSD database consists of 20 people, with 5 poses per person for a total of 500 face images. Extracted image consists of 5 poses using Multiple-Space PCA and each pose is performed by using (2D)2PCA for performing pose classification. Linear polynomial function is used as connection weight of RBFNNs Pattern Classifier and parameter coefficient is set by using Particle Swarm Optimization for model optimization. Proposed (2D)2PCA-based face pose classification performs recognition performance with PCA, (2D)2PCA and RBFNNs.

간호사의 자가통증조절기 사용과 관리에 대한 지식 및 적용실태 (Knowledge and Practice of Patient-controlled Analgesia Use and Management among Nurses)

  • 박미현;김태임
    • 한국간호교육학회지
    • /
    • 제24권1호
    • /
    • pp.5-15
    • /
    • 2018
  • Purpose: The purpose of this study was to investigate the knowledge and practice of patient-controlled analgesia use and management (PCA-UM) among nurses. Methods: Data were collected from 182 nurses employed by four general hospitals having more than 300 beds in Daejeon. The data were collected using self-report questionnaires from November 4 to November 20, 2015. Collected data were analyzed using descriptive statistics, t-test, and ANOVA. Results: The average nurses' knowledge about PCA-UM was 14.8 points out of 20. PCA-UM knowledge was significantly higher for nurses with experience in PCA education (t=3.55, p<.001). Most participants (91.2%) wanted to get PCA training, 86.8% of them provided PCA education to patients after surgery. Approximately 62% of participants regularly evaluated the level of consciousness of patients with PCA. Conclusion: Findings indicate that the knowledge and practice of PCA-UM among nurses were insufficient to provide safe and effective pain management to postoperative patients with PCA. Therefore, it is concluded that it is necessary to develop standardized PCA education programs for nurses to provide safe and effective pain management to postoperative patients with PCA.

주성분 분석법을 이용한 머리전달함수 모형화 기법의 성능 비교 (Comparison of head-related transfer function models based on principal components analysis)

  • 황성목;박영진;박윤식
    • 한국소음진동공학회:학술대회논문집
    • /
    • 한국소음진동공학회 2008년도 춘계학술대회논문집
    • /
    • pp.920-927
    • /
    • 2008
  • This study deals with modeling of Head-Related Transfer Functions (HRTFs) using Principal Components Analysis (PCA) in the time and frequency domains. Four PCA models based on Head-Related Impulse Responses (HRIRs), complex-valued HRTFs, augmented HRTFs, and log-magnitudes of HRTFs are investigated. The objective of this study is to compare modeling performances of the PCA models in the least-squares sense and to show the theoretical relationship between the PCA models. In terms of the number of principal components needed for modeling, the PCA model based on HRIR or augmented HRTFs showed more efficient modeling performance than the PCA model based on complex-valued HRTFs. The PCA model based on HRIRs in the time domain and that based on augmented HRTFs in the frequency domain are shown to be theoretically equivalent. Modeling performance of the PCA model based on log-magnitudes of HRTFs cannot be compared with that of other PCA models because the PCA model deals with log-scaled magnitude components only, whereas the other PCA models consider both magnitude and phase components in linear scale.

  • PDF

수술 전 통증자가조절기에 관한 교육이 수술 후 통증에 미치는 효과 (The Effect of Education on Preoperative PCA upon Postoperative Pain)

  • 서효신;박경숙
    • 성인간호학회지
    • /
    • 제14권3호
    • /
    • pp.449-458
    • /
    • 2002
  • Purpose: The purpose of this study was to compare the effectiveness of a structured preoperative PCA education to that of the usual informal teaching provided by hospital staff in alleviating postoperative pain through more effective use of PCA therapy. Method: As an advanced research, the knowledge about the use of PCA therapy and the attitude about the use of the pain medicine were estimated, and then as a later research, the knowledge about the use of PCA therapy, the attitude about the use of the pain medicine, and the score of the pain were estimated. Result: The experimental group those who received structured preoperative PCA education had statistically significant higher knowledge regarding the use of PCA therapy(p=0.026) and more positive attitudes toward using pain medicine(p=0.004). The experimental group those who received structured preoperative PCA education reported better pain control 4(p=0.002), 8(p=0.014) and 24 hours(p=0.018) after the operation. Conclusion: The structured preoperative PCA education increases the knowledge for the use of patient's PCA therapy and changes their attitude toward the use of the pain medicine positively and consequently enable the use of PCA therapy to be more effective and then finally reduced the patient's pain after the operation.

  • PDF

웨이브릿 영역에서 기하학적 특징과 PCA/LDA를 사용한 얼굴 인식 방법 (Face Recognition Method using Geometric Feature and PCA/LDA in Wavelet Domain)

  • 송영준;김영길
    • 한국콘텐츠학회논문지
    • /
    • 제4권3호
    • /
    • pp.107-113
    • /
    • 2004
  • 본 논문은 얼굴의 기하학적인 특징과 웨이브릿 변환을 사용한 PCA/LDA 복합 방법을 제안하여 얼굴 인식 시스템의 성능을 향상시켰다. 기존의 PCA/LDA 방법은 형태적인 분산의 정도에 따라 유사도를 측정하였기 때문에 얼굴 윤곽선을 정확하게 반영하지 못하였다. 이 단점을 극복하기 위하여 본 논문에서는 눈과 입사이의 거리를 측정하여 질의영상과 훈련영상에서 큰 차이가 있을 경우에는 얼굴내의 눈, 코, 턱 각각의 영역에 대한 에너지를 특징 벡터로 사용하여 기즌의 PCA/LDA로 계산한 유사도를 재산정하였다. 본 논문에서 제안한 방법을 이용해서 ORL 데이터베이스의 400개 얼굴 영상에 대해 모의 실험한 결과 기존의 PCA/LDA 방법보다 약 4%의 인식률 향상이 있음을 보였다

  • PDF

정맥내 통증 자가조절법에 의한 술후통증관리 1,590예에 대한 분석 (Analysis of 1,590 Patients of IV-PCA for Postoperative Pain Management)

  • 송선옥;지대림;구본업
    • The Korean Journal of Pain
    • /
    • 제9권2호
    • /
    • pp.354-362
    • /
    • 1996
  • Background: We started postoperative pain management service using an intravenous patient-controlled analgesia (IV-PCA, PCA), which is known as convenient and effective analgesic method. In this report, we describe the efficacy and safety of PCA and the experience of developing an acute pain service to treat postoperative pain using a PCA. Methods: Practices of an acute pain service were started at a ward for general surgery after preparation of the standardized protocols for PCA. In each patient, PCA was connected following administration of initial loading doses of analgesics at recovery room after operation. All patients were checked by acute pain service team once or twice daily. The scope of acute pain service was gradually spread to other departments such as orthopedic, thoracic, obstetric and gynecologic departments by requests of patients or surgeons. We managed 1,590 patients during first 22 months. among them, nine hundred seventy two cases were prospectively evaluated for their analgesis efficacy and side effects of PCA. Results: The number of patients was increased day by day. the most common type of operation was gastrectomy (21.6%). Commonly used analgesics were nalbuphine (59%) and morphine (37%). The mean duration of PCA attachment was 3.3 days. The degree of analgesia on operation day was good in 44.8% and tolerable in 52.6% of patients. Only 3.9% of patients complained severe pain during their postoperative periods. One elderly patient experienced respiratory depression (0.06%) owing to accidental misuse of PCA by his relatives. Overall patient's satisfaction was over 93%. Conclusion: According to our experiences, we conclude that PCA is an effective, relatively safe and highly satisfactory method for postoperative pain management. Because of these advantages of PCA, the creation of our acute pain service using a PCA was successful and expanded rapidly.

  • PDF

수정된 반복 주성분 분석 기법에 대한 연구 (Modified Recursive PC)

  • 김동규;김아현;김현중
    • 응용통계연구
    • /
    • 제24권5호
    • /
    • pp.963-977
    • /
    • 2011
  • 다변량 자료를 분석함에 있어 자료의 차원을 축소하는데 활용되는 중요한 툴 중 하나인 PCA 분석(주성분 분석, Principal Component Analysis)을 실시간으로 처리해야 하는 적용 분야가 최근 늘고 있다. PCA 분석에서는 표본 공분산 행렬의 고유값과 고유벡터를 도출하는 것이 관건인데, 자료의 양이 방대하며 고차원인 경우 이를 실시간으로 수행하기에는 어려움이 따른다. 이러한 문제점을 해결하기 위해서 Erdogmus 등 (2004)는 일차 섭동 이론(first order perturbation theory)을 활용하여 공분산 행렬의 고유값과 고유벡터를 추정하는 Recursive PCA 방법을 제안했다. 이 방법은 추가된 자료의 양이 많지 않은 경우는 상당히 정확하지만, 추가된 자료의 양이 많아짐에 따라 오차도 커진다는 한계를 가지고 있다. 본 논문은 공분산 행렬의 고유값과 고유벡터가 가지고 있는 수학적 관계를 이용하여 Erdogmus 등 (2004)가 제안한 Recursive PCA 방법을 수정한 Modi ed Recursive PCA 방법을 제안하다. 또한, 모의 실험을 통해 Recursive PCA 방법과 Modi ed Recursive PCA 방법에서의 고유값과 고유벡터 추정값의 정확도를 비교해 보았으며 그 결과 기존 Recursive PCA 방법 보다 정확한 추정이 가능함을 확인할 수 있었다.

A Comparison of the Effect of Epidural Patient-Controlled Analgesia with Intravenous Patient-Controlled Analgesia on Pain Control after Posterior Lumbar Instrumented Fusion

  • Lee, Sang-Hoon;Kim, Kyung-Hyun;Cheong, Seong-Mee;Kim, Su-Mi;Kooh, Mi-Rang;Chin, Dong-Kyu
    • Journal of Korean Neurosurgical Society
    • /
    • 제50권3호
    • /
    • pp.205-208
    • /
    • 2011
  • Objective : Retrospective analysis to compare the effect and complication of epidural patient-controlled analgesia (epidural PCA) with intravenous patient-controlled analgesia (IV PCA) for the treatment of the post-operative pain after posterior lumbar instrumented fusion. Methods : Sixty patients who underwent posterior lumbar instrumented fusion for degenerative lumbar disease at our institution from September 2007 to January 2008 were enrolled in this study. Out of sixty patients, thirty patients received IV PCA group and thirty patients received epidural PCA group. The pain scale was measured by the visual analogue scale (VAS) score. Results : There were no significant difference between IV PCA group and epidural PCA group on the PCA related complications (p=0.7168). Ten patients in IV PCA group and six patients in epidural PCA group showed PCA related complications. Also, there were no significant differences in reduction of VAS score between two groups on postoperative 2 hours (p=0.9618) and 6 hours (p=0.0744). However, postoperative 12 hours, 24 hours and 48 hours showed the significant differences as mean of reduction of VAS score (p=0.0069, 0.0165, 0.0058 respectively). Conclusion : The epidural PCA is more effective method to control the post-operative pain than IV PCA after 12 hours of spinal fusion operation. However, during the first twelve hours after operation, there were no differences between IV PCA and epidural PCA.