• 대한방사선치료학회지
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• 제26권1호
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• pp.11-19
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• 2014

목 적 : 최적화 알고리즘에 적용되는 최적화 인자들의 영향을 고려하여, 가장 적합한 인자 값을 도출함으로써 이상적인 치료계획을 쉽게 설계할 수 있도록 하고자 한다. 대상 및 방법 : 본 연구의 세기조절방사선치료에서 선량계산 알고리즘은 PBC(Pencil Beam Convolution)이고, 최적화 알고리즘은 DVO(Dose Volume Optimizer 10.0.28)이다. 두경부 환자의 세기조절방사선치료에서 치료계획용적의 처방선량은 동시에 2.2 Gy와 2.0 Gy가 될 수 있도록 하였다. 치료계획은 6 MV, 7개의 조사야로 역선량계산방법으로 수립하였다. 최적화 알고리즘 인자는 용적선량-조건강도(Priority, Constrain), 선량부 드럼강도(Smooth)로 선정하고, 각 인자들의 변화량에 따른 치료계획의 영향을 분석하였다. 용적선량-조건강도는 기준 조건강도를 정하고, 비율은 같지만 절대 값은 다른 최적화 과정을 실시하였다. 또한 조건강도의 절대 값에 변화에 따른 치료용적과 주변 정상장기들을 평가하였다. 선량부드럼강도는 기준 조건의 단순 변화와 용적선량-조건강도와 관련시킨 변화를 치료계획에 반영시켰다. 치료계획은 처방선량지수(Conformal Index, CI), 처방선량포함지수(Paddick's Conformal Index, PCI), 선량균질지수(Homogeneity Index, HI)와 각 장기의 평균선량으로 평가하였다. 결 과 : 용적선량-조건강도의 비율을 동일하게 하고 절대 값을 변화 시켰을 때 CI값은 다르지만, PCI는 $1.299{\pm}0.006$, HI는 $1.095{\pm}0.004$, D5%/D95%는 $1.090{\pm}1.011$으로 처방선량에 대한 영향은 유사하였다. 이하선의 평균선량은 용적선량-조건강도의 절대 값이 40, 60, 70, 90으로 증가될 때, 67.4, 50.3, 51.2, 47.1 Gy로 감소하였다. 각각의 치료계획에서 선량부드럼강도를 증가시켰을 때, PCI는 $1.338{\pm}0.006$로 증가된 값을 보였다. 결 론 : 용적선량-조건강도는 절대적인 값보다 각 조건의 비율에 따라 최적화 알고리즘에 영향을 주었다. 절대 값이 다르더라도 같은 비율을 유지하면 유사한 치료계획이 수립되었다. 성공적인 치료계획을 수립하기 위해 특히 보호해야할 정상장기의 용적선량-조건강도는 치료용적의 용적선량-조건강도의 50%이상 되어야한다. 선량부드럼강도는 용적선량-조건강도에 따라 비례하여 증가하거나 감소하여야 한다. 단순히 절대 값으로 적용하면 용적선량-조건강도는 그 조건을 충분히 만족시키지 못한다.

• 임상간호연구
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• 제23권1호
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• pp.83-90
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• 2017

Purpose: This study was to develop evidence-based clinical practice guideline in order to prevent contrastinduced nephropathy (CIN) for patients undergoing percutaneous coronary intervention (PCI). Methods: The guideline was developed based on the "Scottish Intercollegiate Guidelines Network (SIGN)". The first draft of guideline was developed through 5 stages and evaluated by 10 experts.(1) Clinical questions were ensured in PICO format.(2) Two researchers conducted a systematic search through electronic database, identifying 170 studies. We selected 27 full text articles including 16 randomized clinical trials, 7 systematic reviews, and 4 guidelines. Quality of each studies were evaluated by the Cochran's Risk of Bias, AMSTAR, K-AGREEII. Among the studies, 11 studies were excluded.(3) The strength of recommendations were classified and quality of recommendations were ranked.(4) Guideline draft was finalized.(5) Content-validation was conducted by an expert group. All contents were ranked above 0.8 in CVI. Results: Evidence-based clinical practice guideline to prevent CIN was dveloped.(1) The guideline for preventing CIN recommends using 0.9% saline.(2) Standardized rate of fluid therapy is 1 to 1.5ml/kg/hr.(3) Execute hydration for 6~12hrs before PCI and after PCI. Conclusion: This study suggests evidence-based clinical practice guideline for preventing CIN which can be more efficiently used in clinical practice.

• 한국통신학회논문지
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• 제27권7A호
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• pp.683-694
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• 2002

본 논문에서는 2D DWT(Discrete Wavelet Transform)를 이용하여 디지털 영상압축기를 FPGA에서 실시간 동작이 가능하도록 설계하였다. 구현된 웨이블릿을 이용한 영상압축기는 필터링을 수행하는 커널부와 양자화 및 허프만 코딩을 수행하는 양자화/허프만 코더부, 외부 메모리와의 인터페이스를 위한 메모리 제어부, A/D 컨버터로부터 영상을 받아들이기 위한 입력 인터페이스부, 불규칙적인 길이의 허브만 코드값을 32비트의 일정길이로 구성하는 출력 인터페이스부, 메모리와 커널사이 데이터를 정렬하는 메모리 커널 버퍼부, PCI와의 연결을 위한 PCI 입/출력부 그리고 그 밖에 타이밍을 맞추기 위한 여러 작은 모듈들로 구성된다. 열방향 읽기 동작을 행방향 읽기 동작으로 수행하기 위한 메모리 사상방식을 사용하여 외부 메모리에 영상을 저장하고 열방향의 수직 필터링 시 효율적으로 데이터를 메모리로부터 읽을 수 있게 한다. 전체적인 동작은 A/D 컨버터의 필드 신호에 동기하여 전체 하드웨어는 필드 단위로 파이프라인 동작을 하고 필드 단위의 동작은 DWT의 웨이블릿 필터링 레벨에 따라서 동작이 구분된다. 구현된 하드웨어는 APEX2KC EP20K600CB652-7의 FPGA 디바이스에서 11119(45%)개의 LAB와 28352(9％)개의 ESB를 사용하여 하나의 FPGA내에 사상될 수 있었고 부가적인 외부 회로의 필요없이 단일 칩으로써 웨이블릿을 이용한 영상압축을 수행할 수 있었다. 또한 33MHz의 속도에서 초당 30 프레임의 영상을 압축할 수 있어 실시간 영상 압축이 가능하였다.

• 대한한방내과학회지
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• 제44권3호
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• pp.387-401
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• 2023

Objective: This study was conducted to investigate the preventive effect of herbal medicines on restenosis after percutaneous coronary intervention (PCI) by reviewing randomized controlled trials (RCTs). Methods: RCTs were searched for herbal medicine treatment after PCI using eight online databases (PubMed, CNKI, Wanfang, J-STAGE, OASIS, ScienceON, KTKP, and KISS). Studies that confirmed restenosis through coronary angiography at follow-up were selected according to the inclusion and exclusion criteria. The primary outcome was the restenosis rate, and the secondary outcome was the angina recurrence rate. Data were extracted from the final selected studies according to the research methodology and then analyzed with Review Manager 5.4.1. Study quality was assessed using Cochrane's risk-of-bias (RoB) tool. Results: Of the 252 papers obtained through the primary search, nine studies that met the selection criteria were finally selected. In these nine studies, herbal medicine combined with western medicine was used for the experimental group, and western medicine treatment was used alone for the control group. The meta-analysis result revealed that the restenosis rate and angina recurrence rate were significantly lower in the experimental group than in the control group (RR=0.34, 95% CI: 0.22-0.53, p<0.00001, I²=0% and RR=0.47, 95% CI: 0.29-0.78, p=0.004, I²=0%, respectively). Furthermore, the quality of studies assessed by Cochrane's RoB was low. Conclusions: This study showed that the combined treatment of herbal medicine and western medicine was effective in preventing restenosis and angina after PCI. As the number of papers included in this study was small, a large number of high-quality clinical studies should be considered in the future.

• Korean Journal of Radiology
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• 제23권5호
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• pp.539-547
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• 2022

Objective: To investigate the association between functional tumor burden of peritoneal carcinomatosis (PC) derived from diffusion-weighted imaging (DWI) and overall survival in patients with advanced ovarian carcinoma (OC). Materials and Methods: This prospective study was approved by the local research ethics committee, and informed consent was obtained. Fifty patients (mean age ± standard deviation, 57 ± 12 years) with stage III-IV OC scheduled for primary or interval debulking surgery (IDS) were recruited between June 2016 and December 2021. DWI (b values: 0, 400, and 800 s/mm²) was acquired with a 16-channel phased-array torso coil. The functional PC burden on DWI was derived based on K-means clustering to discard fat, air, and normal tissue. A score similar to the surgical peritoneal cancer index was assigned to each abdominopelvic region, with additional scores assigned to the involvement of critical sites, denoted as the functional peritoneal cancer index (fPCI). The apparent diffusion coefficient (ADC) of the largest lesion was calculated. Patients were dichotomized by immediate surgical outcome into high- and low-risk groups (with and without residual disease, respectively) with subsequent survival analysis using the Kaplan-Meier curve and log-rank test. Multivariable Cox proportional hazards regression was used to evaluate the association between DWI-derived results and overall survival. Results: Fifteen (30.0%) patients underwent primary debulking surgery, and 35 (70.0%) patients received neoadjuvant chemotherapy followed by IDS. Complete tumor debulking was achieved in 32 patients. Patients with residual disease after debulking surgery had reduced overall survival (p = 0.043). The fPCI/ADC was negatively associated with overall survival when accounted for clinicopathological information with a hazard ratio of 1.254 for high fPCI/ADC (95% confidence interval, 1.007-1.560; p = 0.043). Conclusion: A high DWI-derived functional tumor burden was associated with decreased overall survival in patients with advanced OC.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2002년도 ITC-CSCC -1
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• pp.145-148
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• 2002

In a network communication process, cryptographic algorithms play important role for secure process. This paper presents a new system architecture named "DCCS." This system can handle flexible operations of both cryptographic algorithms and the keys. For experimental evaluation, two representative cryptographic algorithms DES and Triple-DES are designed and implemented into an FPGA chip on the SEBSW-1. Then the developed board is confirmed to change its cryptographic algorithms dynamically. Also its throughput confirmed the ability of the real-time net-work use of the designed system.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2000년도 하계종합학술대회 논문집(2)
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• pp.254-257
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• 2000

In this paper, we propose a structure of the modified AAL. The ATM adaptation layer(AAL) is described in HDL and implemented in FPGA, which plays a role in receiving of HDTV TS packets over ATM networks. Also We designed the PCI interface module which is used for monitoring and analyzing the HDTV TS packets. The designed FPGA chip operates at 20 MHz.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2000년도 추계종합학술대회 논문집(1)
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• pp.209-212
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• 2000

This paper discusses performance evaluation methodologies for wired/wireless Ethernet adaptors. This paper defines test cases for performance evaluation of LAN adaptor and its environments. Performance evaluation of LAN adaptor is mote complex as compared with interconnection devices such as Ethernet HUB and Ethernet switch, because its performance depends on the system on which the adaptor is plugged. Such dependencies include CUP type, RAM size, system bus architecture(PCI bus clock), etc.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2000년도 전력전자학술대회 논문집
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• pp.61-65
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• 2000

In this paper We have developed the high-speed controller for haptic control. The proposed controller is based on the PCI/FPGA technology which can calculate the real position and transmit the force data to device rapidly. The haptic system is composed of 6DOF force display device high-speed controller. The developed system will be used on constructing the dynamical virtual environment. To show the efficiency of our system we designed simulation program of force-reflecting. As the result of the experiment we found that the controller has much higher resolution than some other controller It is so efficient in a 1 PC-based system with 1[kHz] haptic interrupt cycle.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 제36회 하계학술대회 논문집 D
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• pp.3034-3036
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• 2005

High speed PC-based digital I/O system, PCI-bus master and slave. set is developed, which features are distributed structure, input/output function interchangeability by switch settings, and high speed(20Mbps). Library and application software for a DIO system that have a secure and a convenient functionality are developed.