• Title/Summary/Keyword: PC6

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Comparison of the Pathogenicity of Infectious Hematopoietic Necrosis Virus Genotypes Isolated from Rainbow Trout in Gangwon Province (무지개송어에서 분리된 IHNV (감염성 조혈 괴사바이러스) 유전자형에 따른 병원성 비교)

  • Lee, Chang-Ju;Kim, Kwang-Il;Han, Yu-Seon;Jegal, Myeong-Eun;Kim, Yung-Jin
    • Journal of Life Science
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    • v.31 no.6
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    • pp.574-580
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    • 2021
  • This study investigated the pathogenicity of different genotypes of infectious hematopoietic necrosis virus (IHNV) strains isolated from infected rainbow trout in Gangwon Province. RtPc0314c and RtPc0314g strains belonging to the JRt-Shizuoka lineage and RtPc0816g strain belonging to the JRt-Nagano lineage showed 100% cumulative mortality when inoculated at a high titer. In addition, more rapid necrosis was observed in rainbow trout infected with RtPc0314c and RtPc0314g mutations. When inoculated at a low titer, 100% mortality was not observed until the end of the experiment, but the mortality was higher in rainbow trout infected with a mutant strain belonging to the JRt-Shizuoka linage than a mutant strain belonging to the JRt-Nagano lineage. A histopathological analysis showed a clear signature of infection in kidney and spleen tissues upon infection with RtPc0314c and RtPc0314g but no signature of infection associated with the Rt03186 strain. Based on the results in this study, it seems that strains belonging to the JRt-Shizuoka lineage in Gangwon Province IHNV are more pathogenic.

기획 / Post PC를 겨냥하라!

  • Korea Database Promotion Center
    • Digital Contents
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    • no.6 s.121
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    • pp.90-96
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    • 2003
  • 지난해까지만 하더라도 PDA로 대표되던 포스트PC는 미래 '국내 IT 산업 성장의 핵심 견인차'로 주목받았다. 머지않아 PC산업의 일부분을 대체할 것이라는 장밋빛 전망에도 이의를 제기하는 사람이 드물 정도였다. 그러나 지금 상황을 살펴보면 가시적인 성과는 보이지 않고 기대했던 시장 또한 더디게 성장하는 상태다. 하지만 '디지털 융합현상'과 함께 '디지털콘텐츠'가 결합하면서 기업들은 '신대륙' 개척에 나서고 있다. 이에 산업자원부 산하 전자부품연구원에서 [Post PC백서]를 통해 국내 시장 현황과 기술동향, 소비자 조사 결과를 발표했다. 그 내용을 발췌 수록한다. 수요자 조사 및 시장현황 분석을 통해 국내 'Post PC'시장의 가능성과 하드웨어와 함께 발전하는 디지털콘텐츠의 미래도 엿보도록 하자.

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정보기술(情報技術) 유출 예방을 위한 기업내(內) 컴퓨팅 환경 최적화 방안 연구

  • Song, Seong-Keun;Park, Ji-Sook;Woo, Jae-Hyeon;Lim, Jong-In
    • Review of KIISC
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    • v.18 no.6
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    • pp.43-57
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    • 2008
  • 기업 내 정보기술 유출의 대부분은 내부 근무자에서 비롯되고 있다. 본 연구는 기업 내부 근무자들의 사무환경에서 정보기술 유출 예방을 위해 적용하고 있는 기술적 사례들을 4개의 측면(PC내 정보가 PC 인터페이스 장치에 의해 외부로 나가는 방법을 통제, 네트워크를 통해 사외로 나가는 방법을 통제, PC내 정보를 암호화 저장, 개인 PC를 더미 터미널로 사용하고 실 정보는 서버로 저장하는 네트워크 컴퓨팅)으로 고찰하고 그에 따른 최적화 방안으로 복합형 모델을 제시하면서 이를 적용한 사례와 정책적 요소를 제시하고자 한다.

Study on the impact of each family communication type on children's use of media (가족의 커뮤니케이션 유형이 아동의 미디어 이용에 미치는 영향에 관한 연구)

  • Lee, Woo-Hyun;Lim, Shang-Ho
    • Journal of Digital Convergence
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    • v.11 no.1
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    • pp.173-179
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    • 2013
  • For this study, we conducted a survey targeting elementary school students to examine how the type of family communication shows differences in the children's use of media to draw up effective measures to use media. The result of study is that meaningful differences showed according to the time spent watching TV(F=6.719, p<.05) and using PC(F=7.713, p<.05) or cell phone(F=6.404, p<.05). The authoritative type pursuing obedience preferred entertainment programs and spent much time watching TV and preferred entertainment games when using a PC. The deliberating type pursuing conversations preferred educational and informative programs when watching TV and informative programs when using a PC. This study is meaningful in that it presents lessons learned to draw up measures for children to effectively use media based on the study results.

The molecular mechanism of propionate-regulating gluconeogenesis in bovine hepatocytes

  • Rui Pang;Xiao Xiao;Tiantian Mao;Jiajia Yu;Li Huang;Wei Xu;Yu Li;Wen Zhu
    • Animal Bioscience
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    • v.36 no.11
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    • pp.1693-1699
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    • 2023
  • Objective: Cows that are nursing get around 80% of their glucose from liver gluconeogenesis. Propionate, a significant precursor of liver gluconeogenesis, can regulate the key genes involved in hepatic gluconeogenesis expression, but its precise effects on the activity of enzymes have not yet been fully elucidated. Therefore, the aim of this study was to investigate the effects of propionate on the activity, gene expression, and protein abundance of the key enzymes involved in the gluconeogenesis of dairy cow hepatocytes. Methods: The hepatocytes were cultured and treated with various concentrations of sodium propionate (0, 1.25, 2.50, 3.75, and 5.00 mM) for 12 h. Glucose content in the culture media was determined by an enzymatic coloring method. The activities of gluconeogenesis related enzymes were determined by enzyme linked immunosorbent assay kits, and the levels of gene expression and protein abundance of the enzymes were detected by real-time quantitative polymerase chain reaction and Western blot, respectively. Results: Propionate supplementation considerably increased the amount of glucose in the culture medium compared to the control (p<0.05); while there was no discernible difference among the various treatment concentrations (p>0.05). The activities of cytoplasmic phosphoenolpyruvate carboxylase (PEPCK1), mitochondrial phosphoenolpyruvate carboxylase (PEPCK2), pyruvate carboxylase (PC), and glucose-6-phosphatase (G6PC) were increased with the addition of 2.50 and 3.75 mM propionate; the gene expressions and protein abundances of PEPCK1, PEPCK2, PC, and G6PC were increased by 3.75 mM propionate addition. Conclusion: Propionate encouraged glucose synthesis in bovine hepatocytes, and 3.75 mM propionate directly increased the activities, gene expressions and protein abundances of PC, PEPCK1, PEPCK2, and G6PC in bovine hepatocytes, providing a theoretical basis of propionate-regulating gluconeogenesis in bovine hepatocytes.

IPv6 / IPv6 DNS Set Up and Work Analysis From Multiple Operating System (다양한 OS환경(사용자 PC)에서의 IPv6 / IPv6 DNS 설정 및 동작 분석)

  • Kim, Jin-Seok;Seo, Yu-Hwa;Lee, Ki-Young;Shin, Yong-Tae
    • Proceedings of the Korean Information Science Society Conference
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    • 2007.06d
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    • pp.327-332
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    • 2007
  • 현재 전 세계는 IPv4 주소 자원의 고갈에 대비한 IPv6의 도입을 위해 국가 차원의 전략적인 노력을 기울이고 있으며, 이에 따라 IPv4망에서 IPv6망으로의 안정적인 전이를 위한 상호 운영기술이 지속적으로 개발되고 있다. 이러한 기술을 적용하기 위한 다양한 응용 프로그램의 운영을 위해서 IPv6 뿐만 아니라 IPv6 기반의 Recursive DNS 기술도 그 핵심적인 요소라 할 수 있다. 그렇지만 IPv6 및 IPv6 DNS를 구축과 동시에 사용자 PC의 OS에도 IPv6 및 IPv6 DNS가 설정되어야 한다. 그러나 사용자가 사용하는 운영체제의 종류가 다양하기 때문에 운영체제별 동작도 다르다. 따라서 IPv6 및 IPv6 Recursive DNS을 사용하기 위해서는 사용자 PC의 서로 상이한 운영체제별 IPv6 및 IPv6 DNS 동작을 파악해야만 한다. 이에 본 논문은 운영체제별 IPv6 및 IPv6 DNS 동작을 확인하고 IPv6 및 IPv6 DNS 구축시 고려해야 할 가이드라인을 제시한다.

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The Effects of Perpendicular Needling Laogong ($PC_8$) on the Improvement of Cerebral Hemodynamics in Rats (노궁(勞宮)($PC_8$) 직자(直刺)가 백서(白鼠)의 뇌혈류력학(腦血流力學)에 미치는 영향)

  • Heo, Jin;Kim, Jung-Ho;Kim, Young-Il
    • Journal of Acupuncture Research
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    • v.28 no.4
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    • pp.19-35
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    • 2011
  • Objectives : This study was designed to investigate the effects of acupuncturing $PC_8$ used perpendicular needling method determine the mechanism of action of acupuncturing $PC_8$ by measuring the changes of regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in normal rats. Methods : This study also investigated the effects of acupuncturing $PC_8$ on the change of rCBF in cerebral ischemic rats, and revealed the mechanism of its action. In addition, the effects of acupuncturing $PC_8$ on focal ischemic brain injury was studied in cerebral ischemic rats. Results : 1. Acupuncturing $PC_8$ significantly increase rCBF but decreased MABP in normal rats. 2. Acupuncturing $PC_8$ increased of rCBF was significantly inhibited by pretreatment with indomethacin (1mg/kg, i.p.), an inhibitor of cyclooxygenase in normal rats. 3. Acupuncturing $PC_8$ increased of rCBF was significantly inhibited by pretreatment methylene blue (10 ${\mu}g$/kg, i.p.), an inhibitor of guanylate cyclase in normal rats. 4. Acupuncturing $PC_8$ was significantly improved the rCBF than control group increased unstable in cerebral ischemic rats. 5. Acupuncturing $PC_8$ was not significantly improved the rCBF than control group by pretreatment with indomethacin (1mg/kg, i.p.), an inhibitor of cyclooxygenase in cerebral ischemic rats. 6. Acupuncturing $PC_8$ was significantly increased the rCBF than control group by pretreatment methylene blue ($10{\mu}g$/kg, i.p.), an inhibitor of guanylate cyclase in cerebral ischemic rats. Conclusions : In conclusion, our study suggested that acupuncturing $PC_8$ can increase rCBF in normal state, and improve stability of rCBF in ischemic state. In addition, we suggested that mechanisms related with acupuncturing $PC_8$ was involved in the guanylate cyclase pathway.

Morphological, Mechanical and Rheological Properties of Poly(acrylonitrile-butadiene-styrene)/Polycarbonate/Poly$({\varepsilon}-caprolactone)$ Ternary Blends

  • Hong, John-Hee;Song, Ki-Heon;Lee, Hyung-Gon;Han, Mi-Sun;Kim, Youn-Hee;Kim, Woo-Nyon
    • Macromolecular Research
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    • v.15 no.6
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    • pp.520-526
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    • 2007
  • The effects of poly($({\varepsilon}$-caprolactone) (PCL) on poly(acrylonitrile-butadiene-styrene) (ABS) and polycarbonate (PC) blends were studied. Blends of ABS/PC (70/30, wt%) with PCL as a compatibilizer were prepared by a twin screw extruder. From the glass transition temperature $(T_g)$ results of the ABS/PC blends with PCL, the $T_g$(PC) of the ABS/PC (70/30) blends decreased with increasing PCL content. From the results of the morphology of the ABS/PC (70/30) blends with PCL, the phase separation between the ABS and PC phases became less significant after adding PCL in the ABS/PC blends. In addition, the morphological studies of the ABS/PC blends etched by NaOH indicated that the shape of the droplet was changed from regular round to irregular round by adding PCL in the ABS/PC blends. These results for the mechanical properties of the ABS/PC blends with PCL indicated that the tensile, flexural and impact strengths of the ABS/PC (70/30) blends peaked at a PCL content of 0.5 phr. From the results for the rheological properties of the ABS/PC (70/30) blends with PCL content, the storage modulus, loss modulus and complex viscosity increased at PCL content up to 5 phr. From the above results of the $T_g$, mechanical properties, morphology and complex viscosity of the ABS/PC blends with PCL, it was concluded that the compatibility was increased with PCL addition in the ABS/PC (70/30, wt%) blends and that the optimum concentration of PCL as a compatibilizer is 0.5 phr.

Effects of Phosphatidylcholine and Phosphatidylethanolamine from Egg Yolk on Thermal Oxidation of Canola Oil (달걀 노른자에서 분리한 포스파티딜콜린과 포스파티딜에탄올아민이 카놀라유의 가열산화에 미치는 영향)

  • Kim, Kang-Hyun;Choe, Eun-Ok
    • Korean Journal of Food Science and Technology
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    • v.40 no.6
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    • pp.611-620
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    • 2008
  • The principal objective of this study was to assess the effects of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) extracted from egg yolk on the oxidation of tocopherol-stripped canola oil and its browning, as well as their content changes during 12 hr of heating at $180^{\circ}C$. PC and/ or PE contents in the oil were measured at 200, 500, 1,000, or 2,000 ppm. PL contents in the oil and oil browning were determined by high performance liquid chromatography (HPLC) and spectrophotometry, respectively. The oil oxidation was evaluated by the combination of fatty acid composition, conjugated dienoic acid content, and p-anisidine value. PC was degraded at a slower rate than PE during heating and the co-presence of PE reduced its rate of degradation. PE increased oil browning more profoundly than PC did. PC significantly reduced oil oxidation during heating; however, we noted a possible antagonism between PE and PC in reducing the oil oxidation. Egg yolk PC was a better antioxidant in oil oxidation during heating.