• 제어로봇시스템학회논문지
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• 제8권12호
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• pp.1036-1040
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• 2002

To process data of digital linescan camera, the frame grabber is essential to handle the data in low-level and in high speed more than 30 MHz stably. Traditional approaches to the development of hardware in vision system for the special purpose are mai y based on PC system, and are expensive and gigantic. Therefore, there are many difficulties in applying those in the field. So we investigate, in this paper, the implementation of FPGA for real-time processing of digital linescan camera. The system is not based on PC, but electronic device such as micropncessor. So it is expected that the use of FPGAs for low-level processing represents a fast, stable and inexpensive system. The experiments are carried out on the web guiding system in order to show the efficiency of the new image processor.

• 동의생리병리학회지
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• 제17권6호
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• pp.1524-1527
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• 2003

In this study, we demonstrated the antioxidant effect of the Caesalpinia sappan L. extract through the scavenging effect against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and the protective effect on protein damage and PC12 cells against cupric ion/hydrogen peroxide. Its IC/sub 50/ value of the scavenging effect against DPPH radical was 7.7 ㎍. Protection of its extract against oxidative bovine serum albumin (BSA)damage induced by hydrogen peroxide was more effective than that of vitamin C. The protective effect on PC12 cells by hydrogen peroxide was shown to be more potent in is extract than in vitamin C. DNA fragmentation analysis also supports this result.

• The Korean Journal of Physiology and Pharmacology
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• 제10권4호
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• pp.207-212
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• 2006

Mitochondrial permeability transition has been shown to be involved in neuronal cell death. Mitochondrial monoamine oxidase (MAO)-B is considered to play a part in the progress of nigrostriatal cell death. The present study examined the effect of MAO inhibitors against the toxicity of 1-methyl-4-phenylpyridinium $(MPP^+)$ in relation to the mitochondrial permeability transition. Chlorgyline (a selective inhibitor of MAO-A), deprenyl (a selective inhibitor of MAO-B) and tranylcypromine (nonselective inhibitor of MAO) all prevented cell viability loss, cytochrome c release, caspase-3 activation, formation of reactive oxygen species and depletion of GSH in differentiated PC12 cells treated with $500\;{\mu}M$$MPP^+$. The MAO inhibitors at $10\;{\mu}M$ revealed a maximal inhibitory effect and beyond this concentration the inhibitory effect declined. On the basis of concentration, the inhibitory potency was tranylcypromine, deprenyl and chlorgyline order. The results suggest that chlorgyline, deprenyl and tranylcypromine attenuate the toxicity of $MPP^+$ against PC12 cells by suppressing the mitochondrial permeability transition that seems to be mediated by oxidative stress.

• 한국생물물리학회:학술대회논문집
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• 한국생물물리학회 1998년도 학술발표회
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• pp.30-30
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• 1998

The effects of capsaicin on phospholipase (PLC)-induced capacitative $Ca^{2＋}$ entry (CCE) were investigated in PC12 cells. Capsaicin inhibited one of PLC-linked signal, extracellular ATP-induced norepinephrine secretion with a concentration range, 10-100 $\mu$M. Capsaicin did not inhibit the peak portion of extracellular ATP-mediated [Ca$^{2＋}$]i rise, but it recovered more rapidly to the normal level of [Ca$^{2+}$]i from the sustained [Ca$^{2+}$]i level.(omitted)ted)

• 융합보안논문지
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• 제6권3호
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• pp.79-86
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• 2006

본 논문에서는 광기전력 효과를 이용한 적외선 센서(SHARP사의 GP2D12)모듈의 거리에 따른 센서의 감도와 물체와 센서가 이루는 각도의 변화에 대한 센서의 감도를 측정하여 측정된 센서값을 블루투스를 이용해서 근거리에 있는 PC로 전송하고 전송된 값을 프로그램에 의하여 분석하였다. 분석한 결과 적외선 센서의 특성을 프로세서에서 바로 측정하였을 때와 측정된 값을 블루투스 통신을 이용하여 전송하였을 때 비교 값에 차이를 나타내지 않았다. 따라서 블루투스를 이용하여 100m이내의 근거리에 있는 물체를 적외선 센서로 측정 할 수 있음을 알 수 있었다.

• 한국정밀공학회지
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• 제12권8호
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• pp.131-139
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• 1995

In this study, small size stacker Crane for automatic ware house and interface circuit is designed and manufactured. IBM-PC is used as a controller. At 50kg$_{f}$ load, optimal motion velocity is 20 mm/min for X and Y axis and 12 mm/min for Z axis. Position fesolution is 0.005 mm and repeatability is .+-. 0.025 mm. Through characteristic experiment, effectiveness of the designed and manufactured stacker crane. PC control program, and design of interface circuit and construction of control system are shown. From these results, the developed stacker crane can be apply to FMS(Flexible Manufacturing System) and FA(Factory Automation) of industrial field.d.

• 한방안이비인후피부과학회지
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• 제17권1호
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• pp.94-103
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• 2004

Objective: This study was performed to detennine the depigmenting effects of Kamibongpungtongsung-San. Methods: To determine the depigmenting effects of Kamibangpungtongsung-San. we measured the degree of tyrosinase inhibition, melanin production & cell viability in cultured B16 melanoma cells, UV screen and cytoprotective effects on PC12 cells injured by hydrogen peroxide. Results: Komibangpungtongsung-San did not show inhibitory effects on melanin production in melanoma cells, UV screen and cytoprotective effects on PC12 cells injured by hydrogen peroxide. However it showed mild inhibitory effects on tyrosinase activity. Conclusion : This study shows that Kamibangpungtongsung-San, a generally used prescription for dermatologic diseases, do not have depigmenting effects via tyrosinase inhibition. Therefore, the depigmenting effect and mechanism of depigmentation by Kamibangpungtongsung-San need to be evaluated and investigated in other directions.

• BMB Reports
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• 제44권5호
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• pp.312-316
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• 2011

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its toxic metabolite 1-methyl-4-phenylpyridium ion (MPP$^+$) have been shown to induce Parkinson's disease-like symptoms as well as neurotoxicity in humans and animal species. Recently, we reported that maintenance of redox balance and cellular defense against oxidative damage are primary functions of the novel antioxidant enzyme cytosolic NADP$^+$-dependent isocitrate dehydrogenase (IDPc). In this study, we examined the role of IDPc in cellular defense against MPP$^+$-induced oxidative injury using PC12 cells transfected with IDPc small interfering RNA (siRNA). Our results demonstrate that MPP$^+$-mediated disruption of cellular redox status, oxidative damage to cells, and apoptotic cell death were significantly enhanced by knockdown of IDPc.

• 한국수정란이식학회:학술대회논문집
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• 한국수정란이식학회 2006년도 The 6th Intermational Symposium on Developmental Biotechnology
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• pp.15-15
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• 2006

• 한방안이비인후피부과학회지
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• 제16권2호
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• pp.79-95
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• 2003

Objectives: This study was performed to investigate the depigmentation effects of Salt, Acetum, Sesami Semen Nigrum. Methods: Inhibition of tyrosinase activity, melanin production & cell viability in cultured B16 melanoma cells, UV screen and cytoprotective effects on PC12 cells injured by hydrogen peroxide were measured. Results: Salt, Acetum, Sesami Semen Nigrum did not show any inhibitory effects of tyrosinase activity & melanin production in melanoma cells, UV screen and cytoprotective effects on PC12 cells injured by hydrogen peroxide. Conclusions: This study shows that Salt, Acetum, Sesami Semen Nigrum which were generally used for the addition in external application do not have the depigmentation effects. Following this, the depigmentation effects of the other addition which were generally used for external application shoud be examined.