• Title/Summary/Keyword: PC-1

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Cytosine Arabinoside-Induced PC12 Cell Death Pathway (Cytosine Arabinoside 유도된 PC12 세포의 사망 경로)

  • Yang, Bo-Gee;Yang, Byung-Hwan;Chai, Young-Gyu
    • Korean Journal of Biological Psychiatry
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    • v.5 no.2
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    • pp.219-226
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    • 1998
  • Cytosine arabinoside(AraC) inhibits DNA synthesis and ${\beta}$-DNA polymerase, an enzyme involved in DNA repair. This, a potent antimitotic agent, is clinically used as an anticancer drug with side effect of severe neurotoxicity. Earlier reports suggested that inhibition of neuronal survival by AraC in sympathetic neuron may be due to the inhibition of a 2'-deoxycytidine-dependent process that is independent of DNA synthesis or repair and AraC induced a signal that is triggers a cascade of new mRNA and protein synthesis, leading to apoptotic cell death in cultured cerebellar granule cells. The present study would suggest whether caspase family(ICE/CED-3-like protease) involved in AraC-induced apoptosis pathway of PC12 cells. It was observed that treatment of PC12 cells with AraC led to decrease of viability by MTT assay and morphology changes, which did not suggest that AraC induced apoptosis in PC12 cells. The mRNA of caspase-1/caspase-3 were expressed in PC12 cells constitutively, and AraC did not activate caspase family. These results suggest that caspase-1/caspase-3 may not be required for AraC-induced cell death pathway in PC12 cells.

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Temperature and the Interfacial Buffer Layer Effects on the Nanostructure in the Copper (II) Phthalocyanine: Fullerene Bulk Heterojunction

  • Kim, Hyo Jung;Kim, Jang-Joo;Jeon, Taeyeol;Kong, Ki Won;Lee, Hyun Hwi
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.275.1-275.1
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    • 2014
  • The effects of the interfacial buffer layer and temperature on the organic bulk heterojunction (BHJ) nanostructures of copper phthalocyanine (CuPc) and fullerene (C60) systems were investigated using real time in-situ x-ray scattering. In the CuPc:C60 BHJ structures, standing-on configured ${\gamma}$-CuPc phase was formed by co-deposition of CuPc and C60. Once formed ${\gamma}$-phase was thermally stable during the annealing upon $180^{\circ}C$. Meanwhile, the insertion of CuI buffer layer prior to deposition of the CuPc:C60 BHJ layer induced lying-down configured CuPc crystals in the BHJ layer. The lying CuPc peak intensity and the lattice parameter were increased by the thermal annealing. This increment of the intensity seemed to be related to the strain at the interface between CuPc:C60 and CuI, which was proportional to the enhancement of the power conversion efficiency of the device.

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The PC Clustering of the SIMD Structure for a Distributed Process of On-line Contingency (온라인 선로상정사고 분산처리를 위한 SIMD 구조의 PC 클러스터링)

  • Jang, Se-Hwan;Kim, Jin-Ho;Park, June-Ho
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.57 no.7
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    • pp.1150-1156
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    • 2008
  • This paper introduces the PC clustering of the SIMD structure for a distributed processing of on-line contingency to assess a static security of a power system. To execute on-line contingency analysis of a large-scale power system, we need to use high-speed execution device. Therefore, we constructed PC-cluster system using PC clustering method of the SIMD structure and applied to a power system, which relatively shows high quality on the high-speed execution and has a low price. SIMD(single instruction stream, multiple data stream) is a structure that processes are controlled by one signal. The PC cluster system is consisting of 8 PCs. Each PC employs the 2 GHz Pentium 4 CPU and is connected with the others through ethernet switch based fast ethernet. Also, we consider N-1 line contingency that have high potentiality of occurrence realistically. We propose the distributed process algorithm of the SIMD structure for reducing too much execution time on the on-line N-1 line contingency analysis in the large-scale power system. And we have verified a usefulness of the proposed algorithm and the constructed PC cluster system through IEEE 39 and 118 bus system.

A Study on the Rheological Properties of Branched Polycarbonates by Melt Polymerization (용융중합에 의한 분지형 폴리카보네이트의 유변학적 특성 연구)

  • Choi, Su-Jung;Yoon, Kyung-Hwa;Kim, Hee-Seung;Yoo, Seung-Yoon;Kim, Youn-Cheol
    • Polymer(Korea)
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    • v.35 no.4
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    • pp.356-362
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    • 2011
  • The branched polycarbonates (B-PCs) with two different branching agents were synthesized from melt polymerization. The contents of branching agent were in the range of 0.001~0.005 mol%. The chemical structure of the synthesized PC was determined by FTIR, $^1H$ NMR, and $^{13}C$ NMR, spectroscopy. The molecular weight, glass transition and degradation temperatures were determined by GPC, DSC, and TGA. The molecular weight of the phloro type B-PC had a lower value than the other one, and the glass transition temperature increased with molecular weight. Compared with linear PC, the rheological properties of the B-PC indicated an increase of complex viscosity in the low frequency region and shear thinning tendency. Power law index(n) representing shear thinning was calculated by linear regression and the values were in the range of 0.483~0.996. The rheological properties of the B-PCs were measured by a dynamic rheometer.

Solvent Extraction of Nd from Chloride Solution with PC88A (염산용액에서 PC88A에 의한 Nd의 용매추출)

  • Lee Gwang-Seop;Lee Jin-Young;Kim Sung-Don;Kim Joon-Soo;Lee Man-Seung
    • Resources Recycling
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    • v.13 no.4
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    • pp.39-45
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    • 2004
  • Solvent extraction experiments of Nd from chloride solution were studied with PC88A. Solvent extraction reaction of Nd with PC88A and the equilibrium constant were evaluated from the extraction experimental data and extraction conditions. Nd$aq^{3+}$ + 1.5 $H_2$$A_2$,org = $NdA_3$,org + 3H/sun $aq^{+}$ , K=0.25 The predicted distribution coefficients of Nd agreed well with the experimental results. The effect of saponification of PC88A on the extraction of Nd and on the change of equilibrium pH was investigated. Saponified PC88A present as a monomer in the organic reaction and enhanced the distribution coefficient of Nd. The initial extraction conditions had a great effect on the equilibrium pH.

(1) 세계 PC 카메라, IMT-2000 시장 전망 - 올해 PC 카메라 생산량 급성장 대만 시장이 주요 고객 될 것

  • 한국광학기기협회
    • The Optical Journal
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    • v.12 no.2 s.66
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    • pp.2-5
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    • 2000
  • 올해 세계 PC & WEB 카메라 생산량은 전년에 비해 3배에 달하는 급성장을 이뤄 1,050만 대가 될 것으로 예상하고 있으며, 이중 가장 많은 비중을 차지할 곳은 대만이다. 올 하반기부터 일본을 시작으로 생산될 IMT-2000은 내년에 1,200만대가 생산될 것으로 보인다. 국내에서는 내년 상반기부터 생산에 들어가 2002년부터 서비스를 할 예정이다.

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Design and Implementation of the PC Execution Process Monitoring System for School Computer Classroom (학교 컴퓨터실을 위한 PC 실행 프로세스 모니터링 시스템의 설계 및 구현)

  • Song, Ji-Hee
    • Journal of The Korean Association of Information Education
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    • v.15 no.1
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    • pp.111-117
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    • 2011
  • Many various researches about the PC execution process monitoring system have studied. Nevertheless, it is hard to find research of a system that multi-PC based each PC can be monitoring and reporting by file type. In this study, it designed and implemented that each PC can be monitoring and reporting by files to a server in multi-PCs' environments. Moreover it can gather and organize informations of reporting. It is expected users can recognize that execution processes are reporting. It causes to reduce execution unnecessary process.

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Monitoring and Controlling of Systems in PC room using SNMP (SNMP를 이용한 PC 실습실 시스템의 모니터링과 제어)

  • Ahn, Seong-Jin;Chung, Jin-Wook
    • The Journal of Korean Association of Computer Education
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    • v.3 no.1
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    • pp.109-115
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    • 2000
  • In this paper, we have designed the management System to monitor and control computers running on MS Windows in the PC room using SNMP. The proposed system has controlling capability to control the status of PC and monitoring functions to have real-time monitoring and process control. In the controlling system, it supports update and setting of the configuration information of PC and backup/restore the information when it happens to be some faults. In the monitoring system, it has monitoring the PC of students, controlling the process on PC, and invoking a new job. This system contributes to enhance the effectiveness of teacher's educational activities in PC room by controlling and monitoring the program running on student's computer.

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Preparation of Properties of PC/PBT Alloy Using MBS Compatibility (MBS상용화제를 사용한 PC/PET Alloy의 제조와 그 물성)

  • Lee, Yong-Moo;Kang, Doo-Whan
    • Applied Chemistry for Engineering
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    • v.5 no.1
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    • pp.54-62
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    • 1994
  • Bisphenol A polycarbonate(PC) and polyethylene terephthalate(PET) was blended with methylmethacrylate-butadiene-styrene(MBS) copolymer for the improvement of impact resistance strength PC/PET alloy blending with PC more than 15 parts to 100 parts of PET usually have poor compatability, but increased the compatability characteristics of PC/PET alloy prepared by addition of MBS compatabilizer. The compatability of PC and PET using compatabilizer, MBS was determined by measuring the thermal characteristics of Tg difference between PC and PET, and crystallization temperature, Tcc. As the Tg difference becoming narrow to $60^{\circ}C$, and Tcc decreasing to $150^{\circ}C$, the comparability of PC and PET was increased. And also tough rate impact strength to PC/PET alloy using MBS was increased, in case more than 15 parts of PC being blended to PET.

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Relationship between Bronchial Sensitivity and Bronchial Reactivity in Asthma (기관지천식 환자에서 기관지 감수성과 기관지 반응성에 관한 연구)

  • Seo, Ki-Youl;Chang, Jung-Hyun;Cheon, Seon-Hee
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.2
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    • pp.341-350
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    • 1998
  • Background: Airway hyperreponsiveness is a cardinal feature of asthma. It consists of both an increased sensitivity of the airways, as indicated by a smaller concentration of a constrictor agonist needed to initiate the brochoconstrictor response and an increased reactivity, increments in response induced subsequent doses of constrictor, as manifested by slopes of the dose-response curve. The purpose of this study is to observe the relationship between bronchial sensitivity and reactivity in asthmatic subjects. Method: Inhalation dose-response curves using methacholine were plotted in 56 asthmatic subjects. They were divided into three groups(mild, moderate and severe) according to clinical severity of bronchial asthma. PC20 were determined from the dose-response curve as the provocative concentration of the agonist causing a 20% fall in FEVl. PC40 were presumed or determined from the dose response curve, using the PC20 and the one more dose after PC20. Reactivity was calculated from the dose-response curve regression line, connecting PC20 with PC40. Results: PC20 were 1.83mg/ml in mild group, 0.96mg/ml in moderate, and 0.34mg/ml in severe. PC40 were 7.l7mg/ml in mild group, 2.34mg/ml in moderate, and 0.75mg/ml in severe. Reactivity were $24.7{\pm}17.06$ in mild group, $46.1{\pm}22.l0$ in moderate, and $59.0{\pm}5.82$ in severe. There was significant negative correlation between PC20 and reactivity (r= -0.70, P<0.01). Conclusion: Accordingly, there was significant negative correlation between bronchial sensitivity and brochial reactivity in asthmatic subjects. However, in some cases, there were wide variations in terms of the reactivity among the subjects who have similar sensitivity. So both should be assessed when the bronchial response tor bronchoconstrictor agonists is measured.

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