• Journal of the Korea Society of Computer and Information
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• v.27 no.3
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• pp.71-77
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• 2022

In this paper, we propose 1×2 array antenna with dual linear polarization characteristics for mmWave band operation. The proposed antenna is designed two microstirp feeding structure and FR-4 substrate, which is thickness 0.4 mm, and the dielectric constant is 4.3. The size of 1×2 array antenna is 2.33 mm×2.33 mm, and total size of array antenna is 13.0 mm×6.90 mm. From the fabrication and measurement results, bandwidths of 1.13 GHz (28.52~29.65 GHz) for port 1 and 1.08 GHz (28.45~29.53 GHz) for port 2 were obtained based on the impedance bandwidth. Cross polarization ratios are obtained from 7.68 dBi to 16.90 dBi in case of vertical polarization, and from 7.46 dBi to 15.97 dBi in case of horizontal polarization for input port 1, respectively. Also, cross polarization ratios are obtained from 8.59 dBi to 13.72 dBi in case of vertical polarization and from 9.03 dB to 14.0 dB in case of horizontal polarization for input port 2, respectively.

• Korean Journal of Optics and Photonics
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• v.33 no.4
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• pp.146-158
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• 2022

The detector of a focal-plane-array mid-wave infrared (MWIR) camera has different response characteristics for each detector pixel, resulting in nonuniformity between detector pixels. In addition, image nonuniformity occurs due to heat generation inside the camera during operation. To solve this problem, in the process of camera manufacturing it is common to use a gain-and-offset table generated from a blackbody to correct the difference between detector pixels. One method of correcting nonuniformity due to internal heat generation during the operation of the camera generates a new offset value based on input frame images. This paper proposes a technique for dividing an input image into block image patches and generating offset values using only homogeneous patches, to correct the nonuniformity that occurs during camera operation. The proposed technique may not only generate a nonuniformity-correction offset that can prevent motion marks due to camera-gaze movement of the acquired image, but may also improve nonuniformity-correction performance with a small number of input images. Experimental results show that distortion such as flow marks does not occur, and good correction performance can be confirmed even with half the number of input images or fewer, compared to the traditional method.

• Herbal Formula Science
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• v.30 no.2
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• pp.37-44
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• 2022

Objectives : The purpose of this study was to examine the effects of Alisma canaliculatum Extract (ACE) on pacemaker potentials of small and large intestinal interstitial Cells of Cajal (ICC) in mice. Methods : We used enzymatic digestions to dissociate the ICC in the small and large intestine in mice. The whole-cell patch-clamp method was used to record pacemaker potentials in ICC. Results : 1. The ICC generated the pacemaker potentials in small intestine in mice. ACE (0.1-1mg/ml) induced membrane depolarization and decreased frequency with concentration-dependent manners. 2. Pretreatment with a Ca²⁺ free solution, Na⁺ 5 mM solution or 2-APB, a nonselective cation channel blocker, stopped the small intestinal ICC pacemaker potentials. In the case of Ca²⁺-free solution, Na⁺ 5 mM solution or 2-APB, ACE had no effects on the membrane depolarizations in small intestinal ICC. 3. The ICC generated the pacemaker potentials in large intestine in mice. Membrane depolarization appears regularly in the small intestine, but irregularly in the large intestine. ACE induced membrane depolarization (0.1-1mg/ml) and increased frequency (0.1-0.5mg/ml). 4. Pretreatment with a Ca²⁺ free solution, Na⁺ 5 mM solution or 2-APB, stopped the large intestinal ICC pacemaker potentials. In the case of Ca²⁺-free solution, Na⁺ 5 mM solution or 2-APB, ACE depolarized the membrane depolarizations in large intestinal ICC. 5. In mice, intestinal transit rate (ITR) values were dose-dependently decreased by the intragastric administration of ACE. Conclusions : These results suggest that ACE can regulate the pacemaker activity of ICC and the reaction by ACE is different from the small and large intestinal ICC, and the control of the intestinal motion by ACE may be caused by many complex processes.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.32 no.1
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• pp.67-75
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• 2022

When acquiring a product having an OS, it is very important to identify the exact kernel version of the OS. This is because the product's administrator needs to keep checking whether a new vulnerability is found in the kernel version. Also, if there is an acquisition requirement for exclusion or inclusion of a specific kernel version, the kernel identification becomes critical to the acquisition decision. In the case of the Linux kernel used in various equipment, sometimes it becomes difficult to pinpoint the device's exact version. The reason is that many manufacturers often modify the kernel to produce their own firmware optimized for their device. Furthermore, if a kernel patch is applied to the modified kernel, it will be very different from its base kernel. Therefore, it is hard to identify the Linux kernel accurately by simple methods such as a specific file existence test. In this paper, we propose a static method to classify a specific kernel version by analyzing function names stored in the symbol table. In an experiment with 100 Linux devices, we correctly identified the Linux kernel version with 99% accuracy.

• Journal of Naturopathy
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• v.11 no.1
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• pp.31-38
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• 2022

Background: New beauty soaps are always subject to evaluation. Purposes: This study performed a human application test and safety evaluation on the cleaning effect of the fine dust mimic of the test product, Daziwar soap bar, on 52 women. Methods: The quantitative change measured the cleaning effect of fine dust before and after washing immediately after spraying the fine mimetic dust on the forearm of 22 women. In addition, the safety was evaluated at 30 minutes, 24 hours, and 48 hours after 24 hours after applying the patch to the woman's back. Results: After one time washing with the soap immediately after spraying dust on the inside of the arm, the amount of the remaining mimetic was statistically significantly decreased in both the test group and the control group (p < .001). However, the washing rate was 99.96% in the experimental group and 75.58% in the control group. The questionnaire was evaluated as 'Good' or higher in terms of efficacy. In the evaluating of adverse reactions after washing fine dust by a dermatologist, there were no reports or observations of specific skin adverse reactions or abnormal findings in the subjects. The safety evaluation was judged as non-irritating in the skin reaction evaluation at 30 minutes, 24 hours, and 48 hours after instillation on the back for 24 hours. Conclusions: The test product, Daziwar soap, was found to be very helpful in cleaning fine dust on the human body and was found to be safe for the human body.

• Journal of Korea Entertainment Industry Association
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• v.14 no.7
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• pp.589-597
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• 2020

The purpose of this study was to verify the acne care improvement effects of natural cosmetics with distilled bamboo vinegar contents and develop the materials for acne cosmetics. For the research subjects, 20 teenage boys and girls were selected and based on random number table, 10 subjects were assigned in the control group that used natural cosmetics (foam cleanser, toner, facial pack) and 10 subjects were assigned in the experimental group that used natural cosmetics with distilled bamboo vinegar contents (foam cleanser, toner, facial pack). The natural cosmetics was used for 12 weeks, and Mark-·Vu facial analysis system was used to measure the sebum, pore size, and redness before using the natural cosmetics, 6 weeks after using the natural cosmetics, and 12 weeks after using the natural cosmetics. For the collected data, SPSS v. 21.0 statistics package program was used for the analysis, and the results are as follows. First, it is a safe natural cosmetics based on the results of the patch test to confirm the skin safety of the natural cosmetics. Second, homogeneity was secured based on the results of the test of homogeneity for the sebum, pore size, and redness of the control group and experimental group. Third, in the verification of acne skin improvement effects of natural cosmetics with distilled bamboo vinegar content, the experimental group had higher reduction rate of changes in the sebum, pore size, and redness on the forehead and right cheek compared to the control group. Therefore, it was identified that the natural cosmetics with distilled bamboo liquid content is safe for the skin and effective for reducing the sebum, pore size, and redness for acne skin. For this reason, it is anticipated for distilled bamboo vinegar to be used in the cosmetics industry.

• The Korean Journal of Physiology and Pharmacology
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• v.26 no.5
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• pp.313-323
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• 2022

Atrial fibrillation (AF) is the most common supraventricular arrhythmia, and it corresponds highly with exercise intensity. Here, we induced AF in mice using acetylcholine (ACh)-CaCl₂ for 7 days and aimed to determine the appropriate exercise intensity (no, low, moderate, high) to protect against AF by running the mice at different intensities for 4 weeks before the AF induction by ACh-CaCl₂. We examined the AF-induced atrial remodeling using electrocardiogram, patch-clamp, and immunohistochemistry. After the AF induction, heart rate, % increase of heart rate, and heart weight/body weight ratio were significantly higher in all the four AF groups than in the normal control; highest in the high-ex AF and lowest in the low-ex (lower than the no-ex AF), which indicates that low-ex treated the AF. Consistent with these changes, G protein-gated inwardly rectifying K⁺ currents, which were induced by ACh, increased in an exercise intensity-dependent manner and were lower in the low-ex AF than the no-ex AF. The peak level of Ca²⁺ current (at 0 mV) increased also in an exercise intensity-dependent manner and the inactivation time constants were shorter in all AF groups except for the low-ex AF group, in which the time constant was similar to that of the control. Finally, action potential duration was shorter in all the four AF groups than in the normal control; shortest in the high-ex AF and longest in the low-ex AF. Taken together, we conclude that low-intensity exercise protects the heart from AF, whereas high-intensity exercise might exacerbate AF.

• Journal of Life Science
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• v.33 no.3
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• pp.227-233
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• 2023

The purpose of this paper was to describe a statistical analysis for the spatial distribution of geographical distances of Erythronium japonicum at Mt. Geumjeong in Korea. The spatial pattern of E. japonicum was analyzed according to the nearest neighbor rule, population aggregation under different plot sizes by dispersion indices, and spatial autocorrelation. Most natural plots of E. japonicum were uniformly distributed in the forest community. Disturbed plots were aggregately distributed within 5 m × 5 m of one another. Neighboring patches of E. japonicum were predominantly 7.5~10 m apart on average. If the natural populations of E. japonicum were disturbed by human activities, then the aggregation occurred in a shorter distance than the 7.5~10 m distance scale. The Morisita index (IM) is related to the patchiness index (PAI) that showed the 2.5 m × 5 m plot had an overly steep slope at the west and south areas when the area was smaller than 5 m × 5 m. When the patch size was one 2.5 m × 5 m quadrat at the west distributed area of Mt. Geumjeong, the cluster was determined by both species characteristics and environmental factors. The comparison of Moran's I values to a logistic regression indicated that individuals in E. japonicum populations at Mt. Geumjeong could be explained by isolation by distance.

• The Korean Journal of Physiology and Pharmacology
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• v.27 no.3
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• pp.267-275
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• 2023

Cardiotoxicity, particularly drug-induced Torsades de Pointes (TdP), is a concern in drug safety assessment. The recent establishment of human induced pluripotent stem cell-derived cardiomyocytes (human iPSC-CMs) has become an attractive human-based platform for predicting cardiotoxicity. Moreover, electrophysiological assessment of multiple cardiac ion channel blocks is emerging as an important parameter to recapitulate proarrhythmic cardiotoxicity. Therefore, we aimed to establish a novel in vitro multiple cardiac ion channel screening-based method using human iPSC-CMs to predict the drug-induced arrhythmogenic risk. To explain the cellular mechanisms underlying the cardiotoxicity of three representative TdP high- (sotalol), intermediate- (chlorpromazine), and low-risk (mexiletine) drugs, and their effects on the cardiac action potential (AP) waveform and voltage-gated ion channels were explored using human iPSC-CMs. In a proof-of-principle experiment, we investigated the effects of cardioactive channel inhibitors on the electrophysiological profile of human iPSC-CMs before evaluating the cardiotoxicity of these drugs. In human iPSC-CMs, sotalol prolonged the AP duration and reduced the total amplitude (TA) via selective inhibition of I_Kr and I_Na currents, which are associated with an increased risk of ventricular tachycardia TdP. In contrast, chlorpromazine did not affect the TA; however, it slightly increased AP duration via balanced inhibition of I_Kr and I_Ca currents. Moreover, mexiletine did not affect the TA, yet slightly reduced the AP duration via dominant inhibition of I_Ca currents, which are associated with a decreased risk of ventricular tachycardia TdP. Based on these results, we suggest that human iPSC-CMs can be extended to other preclinical protocols and can supplement drug safety assessments.

• Smart Media Journal
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• v.12 no.1
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• pp.9-16
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• 2023

Recently, a convolutional neural network (CNN) based system is being developed to overcome the limitations of human resources in the apple quality classification of farmhouse. However, since convolutional neural networks receive only images of the same size, preprocessing such as sampling may be required, and in the case of oversampling, information loss of the original image such as image quality degradation and blurring occurs. In this paper, in order to minimize the above problem, to generate a image patch based graph of an original image and propose a random walk-based positional encoding method to apply the graph transformer model. The above method continuously learns the position embedding information of patches which don't have a positional information based on the random walk algorithm, and finds the optimal graph structure by aggregating useful node information through the self-attention technique of graph transformer model. Therefore, it is robust and shows good performance even in a new graph structure of random node order and an arbitrary graph structure according to the location of an object in an image. As a result, when experimented with 5 apple quality datasets, the learning accuracy was higher than other GNN models by a minimum of 1.3% to a maximum of 4.7%, and the number of parameters was 3.59M, which was about 15% less than the 23.52M of the ResNet18 model. Therefore, it shows fast reasoning speed according to the reduction of the amount of computation and proves the effect.