• Membrane and Water Treatment
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• 제10권2호
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• pp.121-125
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• 2019

Chronic exposure to atrazine (ATR) raises concerns about adverse effects on reproductive functions. We tested our previously validated filtering device, the OBP-based filter, onto a biological model constituted of cultured swine granulosa cells treated for 48 h with media conditioned with 0.1 or $10{\mu}M$ ATR evaluating cell viability and steroidogenesis. The tested atrazine concentrations did not change granulosa cell viability and no filtering effects was observed following treatments with media prepared with differently filtered water. As for steroidogenesis, treatment of water with OBP-based filter containing $10{\mu}M$ atrazine completely suppressed the stimulatory effect of $10{\mu}M$ atrazine on progesterone production as well as the inhibitory effect of $0.1{\mu}M$ ATR on estradiol-$17{\beta}$ production by granulosa cells. Our data demonstrate that the impairment of steroidogenesis induced by ATR is effectively removed after water filtration in the experimental device thus suggesting potential use in biotechnological applications on living cells and/or organisms.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 1993년도 수공학연구발표회논문집
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• pp.409-415
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• 1993

• Journal of Periodontal and Implant Science
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• 제46권4호
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• pp.220-233
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• 2016

Purpose: The aim of this study was to present new a model that allows the study of the bone healing process, with an emphasis on the biological behavior of different graft-to-host interfaces. A standardized "over-inlay" surgical technique combined with a differential histomorphometric analysis is presented in order to optimize the use of critical-size calvarial defects in pre-clinical testing. Methods: Critical-size defects were created into the parietal bone of 8 male Wistar rats. Deproteinized bovine bone (DBBM) blocks were inserted into the defects, so that part of the block was included within the calvarial thickness and part exceeded the calvarial height (an "over-inlay" graft). All animals were sacrificed at 1 or 3 months. Histomorphometric and immunohistochemical evaluation was carried out within distinct regions of interest (ROIs): the areas adjacent to the native bone (BA), the periosteal area (PA) and the central area (CA). Results: The animals healed without complications. Differential morphometry allowed the examination of the tissue composition within distinct regions: the BA presented consistent amounts of new bone formation (NB), which increased over time ($24.53%{\pm}1.26%$ at 1 month; $37.73%{\pm}0.39%$ at 3 months), thus suggesting that this area makes a substantial contribution toward NB. The PA was mainly composed of fibrous tissue ($71.16%{\pm}8.06%$ and $78.30%{\pm}2.67%$, respectively), while the CA showed high amounts of DBBM at both time points ($78.30%{\pm}2.67%$ and $74.68%{\pm}1.07%$, respectively), demonstrating a slow remodeling process. Blood vessels revealed a progressive migration from the interface with native bone toward the central area of the graft. Osterix-positive cells observed at 1 month within the PA suggested that the periosteum was a source of osteoprogenitor elements. Alkaline phosphatase data on matrix deposition confirmed this observation. Conclusions: The present model allowed for a standardized investigation of distinct graft-to-host interfaces both at vertically augmented and inlay-augmented sites, thus possibly limiting the number of animals required for pre-clinical investigations.

• Communications for Statistical Applications and Methods
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• 제19권3호
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• pp.507-516
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• 2012

시계열의 상관구조가 시점에 의존하며 주기적인 상관성을 보이는 계절성 시계열 자료에 대한 시계열 모형들이 비교 분석된다. 주기적 자기회귀이동평균 모형을 소개하고, 실증분석으로 주기적 상관성을 지닌 스위스 Arosa 지방의 성층권 오존 월별 시계열에 계층형 모형인 주기적 자기회귀이동평균 모형과 계절 누적자기회귀이동 평균 모형의 적합을 통하여 주기적 자기회귀이동평균 모형의 우월성을 비교한다.

• The Korean Journal of Pain
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• 제31권4호
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• pp.296-304
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• 2018

Epiduroscopy is defined as a percutaneous, minimally invasive endoscopic investigation of the epidural space. Periduroscopy is currently used mainly as a diagnostic tool to directly visualize epidural adhesions in patients with failed back surgery syndrome (FBSS), and as a therapeutic action in patients with low back pain by accurately administering drugs, releasing inflammation, washing the epidural space, and mechanically releasing the scars displayed. Considering epiduroscopy a minimally invasive technique should not lead to underestimating its potential complications. The purpose of this review is to summarize and explain the mechanisms of the side effects strictly related to the technique itself, leaving aside complications considered typical for any kind of extradural procedure (e.g. adverse reactions due to the administration of drugs or bleeding) and not fitting the usual concept of epiduroscopy for which the data on its real usefulness are still lacking. The most frequent complications and side effects of epiduroscopy can be summarized as non-persistent post-procedural low back and/or leg discomfort/pain, transient neurological symptoms (headache, hearing impairment, paresthesia), dural puncture with or without post dural puncture headache (PDPH), post-procedural visual impairment with retinal hemorrhage, encephalopathy resulting in rhabdomyolysis due to a dural tear, intradural cyst, as well as neurogenic bladder and seizures. We also report for first time, to our knowledge, a case of symptomatic pneumocephalus after epiduroscopy, and try to explain the reason for this event and the precautions to avoid this complication.

• Plant Resources
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• 제3권2호
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• pp.118-122
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• 2000

Many ascomycetes were collected at Mt.Unjang, Pyonsan penisula national park, Mt.Moak Chonbuk provincial park, Daea-ri hebarium and Mt.Whaam from August 1996 to October 1999. They were identified. According to the resulting, Lanzia echinophila, Discina parma, Hypomyces auranticus, Helotium versicolor, Cordyceps militaris f. albino, Isaria sinclairii are newly to Korea. They were designed Korean common names by author.

• Wind and Structures
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• 제17권6호
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• pp.589-608
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• 2013

A model is proposed to analyse the along-wind dynamic response of upwind turbines with horizontal axis under service wind conditions. The model takes into account the dynamic coupling effect between rotor blades and supporting tower. The wind speed field is decomposed into a mean component, accounting for the well-known wind shear effect, and a fluctuating component, treated through a spectral approach. Accordingly, the so-called rotationally sampled spectra are introduced for the blades to account for the effect of their rotating motion. Wind forces acting on the rotor blades are calculated according to the blade element momentum model. The tower shadow effect is also included in the present model. Two examples of a large and medium size wind turbines are modelled, and their dynamic response is analysed and compared with the results of a conventional static analysis.

• 한국수자원학회논문집
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• 제36권2호
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• pp.195-209
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• 2003

본 연구에서는 낙동강 상류유역의 병렬 다목적댐군인 안동 및 임하다목적 댐의 장기간 유입량을 산정하는데 공간추계 신경망모형이 사용되었다. 공간추계 신경망모형은 역전파 알고리즘으로 LMBP와 BFGS-QNBP를 각각 사용하였다. 공간추계 신경망모형의 구조는 입력층, 은닉층 및 출력층의 3개의 층과 차례대로 8-8-2개의 노드로 구성되어 있다. 입력층 노드는 안동 및 임하다목적 댐의 월평균유입량, 월면적강우량, 월별 증발접시 증발량과 월평균기온으로 구성되어 있으며, 자료시계열은 시간적으로 차이가 있다. 공간추계 신경망모형의 훈련을 위하여 추계학적 모형중 하나인 PARMA(1,1)에 의해서 훈련자료를 모의발생시켰으며, 모의발생된 자료는 공간추계 신경망모형의 훈련에 사용되었다. 훈련을 통하여 공간추계 신경망모형의 매개변수인 최적연결강도와 편차를 산정하였다. 산정된 매개변수는 안동 및 임하다목적 댐의 실측자료를 이용하여 공간추계 신경망모형의 검증에 이용되었으며, 통계분석과 수문곡선의 비교를 통하여 우수한 결과를 나타내었다. 따라서 공간추계 신경망모형은 낙동강 상류유역의 병렬저수지군의 장기간 연계운영기법 개발을 위하여 기초적인 자료를 제공하고, 용수분배 및 관리에 도움을 줄 것이다.

• Animal Bioscience
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• 제36권1호
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• pp.132-143
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• 2023

Objective: The aim was to study the influence of cooling milk at 9℃ at the farm versus keeping it at 20℃ on Parmigiano Reggiano cheese lipolysis. Methods: A total of six cheesemaking trials (3 in winter and 3 in summer) were performed. In each trial, milk was divided continuously into two identical aliquots, one of which was kept at 9℃ (MC9) and the other at 20℃ (MC20). For each trial and milk temperature, vat milk (V-milk) and the resulting 21 month ripened cheese were analysed. Results: Fat and dry matter and fat/casein ratio were lower in MC9 V-milk (p≤0.05) than in MC20. Total bacteria, mesophilic lactic acid and psychrotrophic and lipolytic bacteria showed significant differences (p≤0.05) between the two V-milks. Regarding cheese, fat content resulted lower and crude protein higher (p≤0.05) both in outer (OZ) and in inner zone (IZ) of the MC9 cheese wheels. Concerning total fatty acids, the MC9 OZ had a lower concentration of butyric, capric (p≤0.05) and medium chain fatty acids (p≤0.05), while the MC9 IZ had lower content of butyric (p≤0.05), caproic (p≤0.01) and short chain fatty acids (p≤0.05). The levels of short chain and medium chain free fatty acids (p≤0.05) were lower and that of long chain fatty acids (p≤0.05) was higher in MC9 OZ cheese. The principal component analysis of total and free fatty acids resulted in a clear separation among samples by seasons, whereas slight differences were observed between the two different milk temperatures. Conclusion: Storing milk at 9℃ at the herd affects the chemical composition of Parmigiano Reggiano, with repercussion on lipolysis. However, the changes are not very relevant, and since the cheese can present a high variability among the different cheese factories, such changes should be considered within the "normal variations" of Parmigiano Reggiano chemical characteristics.

• 대한토목학회논문집
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• 제28권2B호
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• pp.199-213
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• 2008

본 연구의 목적은 월별 증발접시 증발량과 월별 알팔파 기준증발산량의 모형화를 위한 통합운영방법을 개발하고 적용하는데 있다. 우리나라에서는 장기간동안 증발산계를 이용하여 알팔파 기준증발산량의 관측이 시행되지 않고 있으므로, Penman-Monteith(PM) 공식을 이용하여 산정된 값을 계측된 알팔파 기준증발산량으로 가정하였다. 통합운영 방법은 각각 추계학적 모형과 신경망모형의 적용으로 구성되어 있다. 추계학적 모형은 월별 증발접시 증발량과 월별 알팔파 기준증발산량에 대한 훈련자료의 모의발생을 위하여 적용되었으며, 신경망모형은 관측된 테스트자료를 합리적으로 계산하기 위하여 적용되었다. 고려된 6가지의 훈련패턴 중에서 1,000/PARMA(1,1)/GRNNM-GA 훈련패턴은 제시된 기상인자를 가장 양호하게 평가하였으며, 또한 월별 증발접시 증발량과 월별 알팔파 기준증발산량의 신뢰성있는 자료를 구축할 수 있다. 불확실성 분석은 1,000/PARMA(1,1)/GRNNM-GA 훈련패턴 으로부터 입력층노드의 기상인자를 제거하기 위하여 이용되었으며, 민감하거나 민감하지 않는 기상인자들이 불확실성 분석을 통하여 선택되어 진다. 마지막으로 통합운영방법을 이용하여 최소비용과 노력으로 월별 증발접시 증발량과 월별 알팔파 기준증발산량을 동시에 모형화가 가능하게 되었다.