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Application of Oral Acute Toxic Class Method and Globally Harmonized Classification System on Pesticide (국내에서 농약에 대한 급성경구독성등급법 적용 및 GHS 체계 도입 제안)

  • Jeong, Mi-Hye;You, Are-Sun;Park, Kyung-Hun;Kim, Byung-Seok;Lee, Hee-Dong;Lee, Jae-Bong;Kwon, Oh-Kyung
    • The Korean Journal of Pesticide Science
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    • v.12 no.2
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    • pp.141-147
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    • 2008
  • Globally Harmonized System (GHS) for classification and labelling will provide an internationally agreed hazard classification system of chemical products and for communication of those hazards. This study aimed for establishment of the oral acute toxic class (ATC) method and application of GHS on pesticides. The ATC method was developed for determining $LD_{50}$ estimates of chemical substances with significantly fewer animals than needed when applying conventional $LD_{50}$ tests. We carried out $LD_{50}$ test and ATC test on 13 pesticides, Although methidathion EC and parathion-ethyl EC showed significantly different in $LD_{50}$ values between $LD_{50}$ test and ATC method, there are no difference in toxicity class by GHS. Both tests on the other pesticides showed almost equal results and toxicity class by GHS. Therefore, this study indicated high possibility of application of ATC method and GHS on pesticides.

UTILIZATION OF UNEXPLOITED ALGAE FOR FOOD OR OTHER INDUSTRIAL USES 1. CHEMICAL COMPOSITION OF UNEXPLOITED ALGAE AND EXTRACTION OF ALGAL PROTEIN (미이용해조류의 이용화에 관한 연구 I. 미이용해조류의 성분조성과 조류단백질의 추출)

  • PARK Yeung-Ho;PYEUN Jae-Hyeung;OH Hoo-Kyu;KANG Yeung-Joo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.9 no.3
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    • pp.155-162
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    • 1976
  • Forty one samples from thirty three species of algae (19 from 15 species of Rhodophyceae, 18 from 14 species of Phaeophyceae, 3 from 3 species of Chlorophyceae, and 1 of marine Phanerogams) collected from several locations on the east, west and south coast of Korea, were analyzed for their contents of crude protein, fat, cellulose, ash, nitrogen free extract, amino nitrogen, and total amino acids. For the examination of extractability of algal protein with water, 4 species of algae, Sargassum thunberggi, Grateloupia filicina, Phyllospadix japonica, and Sargassum confusum, were analyzed. And the effect of some precipitation treatments for isolation of algal protein was also tested. As a matter of fact, Rhodophyceae showed high content in crude protein and low in crude fat while the case was opposite for Phaeophyceae and Chlorophyceae. Refering to the content of crude protein and total amino acids, the recommendable algae for protein sources were Sargassum thunbergii, Acrosorium flabellata, Phacelocarpus japonicus, Laurencia okamurai, Laurencia intermedia, Grateloupia filicina, Chondrus ocellatus, Gloiopeltis furcata, Gigartina tenella, Dictyota dichotoma, and Scytosiphon lomentaria. Methanol treatment appeared most effective in precipitation isolation of protein from water extracts whereas pH control method did not so beneficial. The precipitation rate of protein was particularity higher in the extract of Sargassum confusum ana the lowest was makted from the extract of Sargassum thunbergii.

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Studies on Processing ana Keeping Quality of Retort Pouched Foods (3) Preparation and Keeping Quality of Retort Pouched Fried Mackerel Meat Paste (레토르트파우치식품의 가공 및 품질안정성에 관한 연구 (3) 레토르트파우치 튀김어묵의 제조 및 저장중의 품질안정성)

  • LEE Eung-Ho;OH Kwang-Soo;KOO Jae-Geun;PARK Hyang-Suk;CHO Soon-Yeong;CHA Yong-Jun
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.17 no.5
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    • pp.373-382
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    • 1984
  • Processing conditions of retort pouched fried mackerel fish meat paste and quality stability during storage were investigated. The reasonable amounts of added ingredients to the frozen mackerel meat paste were $10\%$ of corn starch, $1\%$ of soybean protein, $1.5\%$ of sodium chloride, $0.6\%$ of monosodium glutamate, $0.3\%$ of alcoholic extract of red pepper, and $0.1\%$ of sodium erythorbate as an antioxidant and also added water corresponding to $10\%$ of the frozen mackerel meat paste. After grinding the defrosted mackerel fish meat paste with ingredients, the meat paste was molded in bar type and fried in soybean oil at $170-180^{\circ}C$ for 3 minutes. The fried mackerel meat paste was cooled, vacuum-packed in laminated plastic film bag (polyester/polyvinylidene chloride/unoriented polypropylene : $12{\mu}m/15{\mu}/50{\mu}m,\;14{\times}19cm$) and finally sterilized at $120^{\circ}C$ for 20 minutes in a hot water circulating retort. The pH, volatile basic nitrogen, moisture content, water activity, color, thiobarbituric acid value, peroxide value, texture and viable bacterial count of products were examined during 100 days of storage at $25{\pm}3^{\circ}C\;and\;5^{\circ}C$. The results showed that products could be preserved in good condition for 100 days at $25{\pm}3^{\circ}C$. Judging from sensory evaluation, the quality of products was not inferior to that of market products.

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Negative Support Reactions of the Single Span Twin-Steel Box Girder Curved Bridges with Skew Angles (단경간 2련 강박스 거더 곡선교의 사각에 따른 부반력 특성)

  • Park, Chang Min;Lee, Hyung Joon
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.16 no.4
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    • pp.34-43
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    • 2012
  • The behaviors of the curved bridges which has been constructed in the RAMP or Interchange are very complicate and different than orthogonal bridges according to the variations of radius of curvature, skew angle and spacing of shoes. Occasionally, the camber of girder and negative reactions can be occurred due to bending and torsional moment. In this study, the effects on the negative reaction in the curved bridge were investigated on the basis of design variables such as radius of curvature, skew angle, and spacing of shoes. For this study, the twin-steel box girder curved bridge with single span which is applicable for the RAMP bridges with span length(L) of 50.0m and width of 9.0m was chosen and the structural analysis to calculate the reactions was conducted using 3-dimensional equivalent grillage system. The value of negative reaction in curved bridges depends on the plan structures of bridges, the formations of structural systems, and the boundary conditions of bearing, so, radius of curvature, skew angle, and spacing of shoes among of design variables were chosen as the parameter and the load combination according to the design standard were considered. According to the results of numerical analysis, the negative reaction in curved bridge increased with an decrease of radius of curvature, skew angle, and spacing of shoes, respectively. Also, in case of skew angle of $60^{\circ}$ the negative reaction has been always occurred without regard to ${\theta}/B$, and in case of skew angle of $75^{\circ}$ the negative reaction hasn't been occurred in ${\theta}/B$ below 0.27 with the radius of curvature of 180m and in ${\theta}/B$ below 0.32 with the radius of curvature of 250m, and in case of skew angle of $90^{\circ}$ the negative reaction hasn't been occurred in the radius of curvature over 180m and in ${\theta}/B$ below 0.38 with the radius of curvature of 130m, The results from this study indicated that occurrence of negative reaction was related to design variables such as radius of curvature, skew angle, and spacing of shoes, and the problems with the stability including negative reaction will be expected to be solved as taken into consideration of the proper combinations of design variables in design of curved bridge.

Effect of a Herb Mixture (HIM-I) on the Protection of the Hematopoietic-Immune System and Self-renewal Tissues against Radiation Damage (면역조혈계 및 재생조직의 방사선 손상에 대한 생약복합물(HIM-I)의 방호 효과)

  • Park, Hae-Ran;Kim, Sung-Ho;Yee, Sung-Tae;Byun, Myung-Woo;Jo, Sung-Kee
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.5
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    • pp.605-612
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    • 2005
  • In previous studies, we evaluated the effect of the 6 energy-tonic or blood-building prescriptions of traditional oriental medicine, and observed that Si-Wu-Tang and Bu-Zhong-Yi-Qi-Tang showed high activity in the protection of the gastrointestinal and hematopoietic organs in irradiated mice. But any of these prescriptions did not show a high activity in the activation of the immune cells. We performed this study to design an herb mixture which protects the self-renewal tissues and also promotes recovery of the immune system against radiation damage. In order to meet all the requirements, we designed a new mixture of 3 edible herbs listed in Korean Food Code. The mixture of Angelim gigas radix, Cnidium officinale rhizoma and Paeonia japonica radix was decocted with hot water, and the activities of the water extract (HIM-I) were evaluated. HIM-1 stimulated the immune cells in a much higher extent than the traditional prescriptions, and promoted dramatically the growth of bone marrow stem cells in vitro. Also, HIM-1 protected digestive and hematopoietic organs against radiation as effectively as the 2 prescriptions, Si-Wu-Tang and Bu-Zhong-Yi-Qi-Tang. On the other hand, it showed high in vitro antioxidative activity that might be considered as a mechanism of the protective effects against radiation. Although the detailed mechanisms of those effects remain to be elucidated, these results indicated that HIM-I might be a useful agent for protection and recovery of body from various risk factor as well as radiation, especially since it is a relatively nontoxic natural product.

Studies on Stability for the Quality of Ginseng Products - 1. Quality Characteristics of Freeze and Spray Dried Red Ginseng Extract Powders - (인삼제품(人蔘製品)의 품질안정성(品質安定性)에 관한 연구(硏究) - 1. 동결(凍結) 및 분무정분(噴霧精粉)의 품질특성(品質特性) -)

  • Choi, Jin-Ho;Byun, Dae-Seok;Park, Kil-Dong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.13 no.1
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    • pp.57-63
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    • 1984
  • This study was designed to compare the quality characteristics of freeze and spray dried red ginseng extract powders(RGEPs) by drying methods, which have been required to maintain the stability for the quality. Chemical compositions, major ginsenoside contents and color intensities of these Products were compared by drying conditions. The moisture absorption rates and optical densities also were compared during storage under maltreatment conditions of a various relative humidities (75, 86and 92 RH) and two different temperatures (37 and $50^{\circ}C$). It was found that decreases of total major ginsenosides contents in freeze and spray dried RGEPs were 5.4 % to 6.7 % during storage for 6 months at $37^{\circ}C$, 75 % RH. When these products packaged with inner seal of Al-foil laminate paper (Al-foil; 9 ${\mu}m$) were stored for 6 months at $37^{\circ}C$, 75 % RH. the moisture absorption rates of freeze and spray dried RGEPs were ranged 42 % to 82 %, 8 % to 16 %, respectively. In storage for 6 months at $37^{\circ}C$, 86 % RH, spray dried RGEP was higher in brown pigment($400{\sim}490nm$) than freeze dried RGEP while freeze dried was higher in pyrazine (278 nm), HMF and furfural (285 nm) than spray dried RGEP. It was found that RGEPs showed a strong anti-oxidative activity by electron donating ability to DPPPH, but there was no significant difference between freeze and spray dried RGEPs.

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Influences of Dietary Fats and Oils on Concentration of Lipids in Serum and Liver of Rats on Hypercholesterolemic Diet -On the Perilla oil and the File fish Oil- (섭취유지(攝取油脂)의 종류(種類)가 고(高)콜레스테롤식이(食餌) 흰쥐의 혈청(血淸) 및 간장(肝臟)의 지질성분(脂質成分)에 미치는 영향(影響) -들깨기름과 말쥐치기름을 중심(中心)으로-)

  • Chung, Seung-Yong;Seo, Maeng-Hee;Park, Pil-Sook;Kang, Jin-Soon;Kang, Jeong-Ock
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.15 no.1
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    • pp.75-81
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    • 1986
  • In order to investigate the effect of file fish oil and perilla oil on lipid components in serum and liver of rats on hypercholesterolemic diet, concentrations of total cholesterol, triglyceride and phospholipid in serum and liver were measured along with high density lipoprotein cholesterol concentration of the serum. Body weight gain and amount of food intake did not differ significantly among different dietary groups. Concentration of total-cholesterol in serum was significantly lower with 5% lard+5% soybean oil, 5% lard+5% perilla oil and 5% lard+5% file fish oil diets than with 10% lard diet. High density lipoprotein cholesterol concentration was highest in 5% lard+5% file fish oil group. Ratio of high density lipoprotein cholesterol to total cholesterol was highest in 5% lard +5% file fish oil group. Concentrations of total cholesterol in liver were not significantly different among all groups, but were slightly low in 5% lard+5% file fish oil and 5% lard+5% perilla oil groups. Concentration of serum triglyceride was significantly lower in 5% lard+5% soybean oil and 5% lard+5% perilla oil groups compared with 10% lard group. Concentration of serum phospholipid was lowest in rats on 5% lard+5% file fish oil diet and was lower in 5% lard+5% soybean oil and 5% lard +5% perilla oil groups than in 10% lard group. Concentration of triglyceride and phospholipid in liver were not significantly different among all groups. but tended to be relatively low in rats on 5% lard+5% perilla oil diet, In conclusion, the results suggest that perilla oil and file fish oil have depressing effects on serum levels of total cholesterol, triglyceride and phospholipid.

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Changes in Physicochemical Properties and Antioxidant Activities according to Different Harvest Times in Black Rice (Oryza sativa L.) (흑미 수확시기에 따른 이화학적 특성 및 항산화 활성 변화)

  • Park, Ji-Young;Han, Sang-Ik;Hur, Yeon-jae;Lee, Yu-Young;Lee, Byung-Won;Sim, Eun-Yeong;Ham, Hyeonmi;Kim, Byeong-Ju;Lee, Chun-Woo;Lee, Sung-Joon;Oh, Sung-Hwan
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.44 no.11
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    • pp.1653-1659
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    • 2015
  • This study compared physicochemical properties and antioxidant activities according to different harvest times in five varieties of black rice (BR). Five cultivars of BR, Nunkeunheukchal (NKHC), Sinnongheugchal (SNHC), Sintoheugmi (STHM), Josaengheugchal (JSHC), and Heugjinju (HJJ), were selected for the study. Cultivars were transplanted on June 20th and cultivated by the Department of Southern Area Crop Science, NICS in Miryang, Korea. Heading dates of NKHC, SNHC, STHM, JSHC, and HJJ were Aug. 17th, Aug. 30th, Sep. 1st, Aug. 20th, and Aug. 12th, respectively. The five different harvest times were as follows; 35, 40, 45, 50, and 55 days after heading date. The highest level of anthocyanin was 35 days after heading date in all varieties. Levels of anthocyanin in NKHC, SNHC, STHM, JSHC, and HJJ were 164, 203, 251, 67, and 210 mg/100 g, respectively. Content of anthocyanin significantly decreased 35 days after heading in four varieties, excluding JSHC. Highest DPPH $IC_{50}$ values were 57, 29, 10, and $27{\mu}g/mL$ in NKHC, SN HC, STHM, and JSHC extracts, respectively. Highest ABTS $IC_{50}$ values were 24, 13, 9, and $11{\mu}g/mL$ in NKHC, SNHC, STHM, and JSHC extracts, respectively. The antioxidant activities were highest 35 days after the heading date and significantly decreased in four varieties, excluding HJJ. The antioxidant activity of HJJ showed no significant difference, according to harvest time. This study suggests that the content of anthocyanin and antioxidant activity could be considered as factors affecting optimal harvest period to produce highly qualified black rice.

A study on Significance of Literary History in Kwon Goohyeon's and Han Yongwoon's Sijo (권구현과 한용운 시조의 문학사적 의의 - 1920-1930년대 시조부흥운동의 재인식 -)

  • Yeo, Ji-Sun
    • Sijohaknonchong
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    • v.23
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    • pp.213-239
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    • 2005
  • Si is a genre which has been steadily loved by Korean, Particularly, 1920's through 1930's, the Revival Movement of Sijo is made by the school of Literary for People, including Choi Namseon, Lee Byeonggi and Lee Eunsang. And Kwon Goohyeon, a member of KAPF, and Han Yongwoon, not belonging to any literary group were interested in Sijo. Kwon Goohyeon, both a member of KAPF and an anarchist has published A Present of Black Room(1927), which is one of the two published in 1920's-1920's saw only two volumes of Sijo works be published: Choi Namseon's 108 Agony(1926) and Kwon's. However, Kwon Goohyeon's work has not been illuminated. compared with Choi Namseon's and the Revival Movement Sijo by the school of Literary for People. It is because Korean literary world has been under the anti-communism ideology since the Liberation of Korea. However, it caused to explore proletarianism Sijo (Joh woon) and proletarianism poetry (Park Yeonghee) that Kwon is a memeber of KAPF and an anarchist. Han Yongwoon, not belonging to any literary group, was very famous as the poet of My Belolved One's Silence(1926), not as a Sijo poet. It means that he s not been illuminated as a Sijo poet. However, his Sijo is enough to contain his various features such as a man of Independence Movement, a Buddhist monk, a lyrical poet and so on. His first Sijo is For Planting Mookoonghwa-Poetry Written in Prison(1922), which has been published four years prior to My Beloved One's. And his affection on Sijo is inferred from the fact that he has constantly published Sijo more than free verse. The aim this thesis is to find out a position of Sijo 1920's through 1930's from a study on Kwon Goohyeon's and Han Yongwoon's Sijo. Sijo, Korean traditional literary genre, was written by most of the poets including not only the school of Literary for People but Kwon Goohyeon and Han Yongwoon 1920's through 1930's. As a result, the writing of Sijo was not a partial movement by the anti-KAPF group, but by a paradigm in 1920's through 1930's.

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The Meta-Educational Implications of Toson-Shibigok ("도산십이곡"에 나타난 메타교육적 함의)

  • Park, Mi-Young
    • Sijohaknonchong
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    • v.23
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    • pp.71-105
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    • 2005
  • Toson-Shibigok(Twelve Songs of Toson) which T'oegye, Yi Hwang, composed has received a lot of attention in terms of its educational implications. These implications have become the essential part of Gojeon Sigas(classic songs and poems), and solid evidence has also been accumulated in the literature. Therefore, the purposes of this study are twofold, that is 1) to explore the impact of T'oegye's fundamental structure of the first education at that time and 2) describe how these educational attitudes will eventually yield meta- educational values. What T'oegye meant by fundamental structure of the first education was that Sijos originated from his own experience should be the vital part of teaching method. One can say that T'oegye's teaching method is more integrative than that of modern literature education in that it includes songs. Not only using his own teaching method, but T'oegye tried to demonstrate his own literary structure to his colleagues and the future generations. In the end, Meta-Education which comprises the heart of recent educational theories well reflects Toegye's theoretical propositions. Rather than giving practical knowledge, his method offers the paradigms of thought patterns and shows the learners' attitudes in approaching the truth. Moreover, T'oegye's teaching method has become a good example to the future generations as well as his contemporary followers. In sum, although a lot of years have passed since he died, T'oegye's Sijo works and life still have invaluable impact on the field of education.

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