• The KIPS Transactions:PartD
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• v.15D no.2
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• pp.257-262
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• 2008

This paper describes the implementations of the application service based on embedded Linux; Personal Audio Recorder (PAR) which uses WiBro network for data communications and CDMA network for voice communications. At PAR, when PAR client starts voice recording on a dual-mode terminal, the CDMA voice data of caller and callee is transmitted to storage server located in the Internet through WiBro network. Then, PAR server stores voice data on storage server according to the call number and call time. In case of shortage of storage space on terminal, PAR makes user to store voice data. And, PAR can search a catalog of stored data on server and play the specific content.

• Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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• 2008.05a
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• pp.196-198
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• 2008

본 논문에서는 LED의 고출력화가 이루어지면서 많이 사용되고 있는 LED MR 타입과 PAR 타입의 램프 배광을 설계하였다. 1W와 5W급의 High power LED를 적용하였고, 1개의 LED가 사용된 빔각 30도의 MR16 램프부터 9개의 LED가 사용된 빔각 60도의 PAR30 램프까지 총 6가지 배광을 구현하고 최대광도로 각각의 성능을 평가하였다. 빔 각을 구현하고 집광시키기 위하여 LED dome 측면부에 소형의 반사판을 설계하였다.

• Proceedings of the Korean Information Science Society Conference
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• 2001.10c
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• pp.319-321
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• 2001

ADSL에서 사용되고 있는 DMT(Discrete Multitone)는 Multicarrier Modulation 기법으로 선로의 특성을 고려하여 고속의 bit-rate를 얻을 수 있다. 그러나 이러한 Multicarrier 신호의 문제점은 바로 높은 PAR(Peak-to-Average Ratio)로, 이 값을 줄이기 위해 여러 가지 기법이 사용되고 있다. 본 논문에서는 현재 PAR을 줄이기 위해 사용되고 있는 여러 기법에 대해서 설명하고, 그 기법들 중에서 PTS(Partial Transmit Sequence)를 개선한 새로운 알고리즘을 제시하여 성능평가를 통해 낮은 복잡도의 계산으로 PTS와 유사한 성능을 보임을 살펴본다.

• Molecules and Cells
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• v.37 no.1
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• pp.9-16
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• 2014

ADP-ribosylation is a type of posttranslational modification catalyzed by members of the poly(ADP-ribose) (PAR) polymerase superfamily. ADP-ribosylation is initiated by PARPs, recognized by PAR binding proteins, and removed by PARG and other ADP-ribose hydrolases. These three groups of proteins work together to regulate the cellular and molecular response of PAR signaling, which is critical for a wide range of cellular and physiological functions.

• IMMUNE NETWORK
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• v.5 no.4
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• pp.193-198
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• 2005

Background: Protease-activated receptor 2 (PAR2) belongs to a family of G protein coupled receptors activated by proteolytic cleavage. Trypsin-like serine proteases interact with PAR2 expressed by a variety of tissues and immune cells. The aim of our study was to investigate whether PAR2 stimulation can lead to the activation of human mac rophages. Methods: PAR2-mediated proliferation of human macrophage cell line THP-1 was measured with MTT assay. We also examined the extracellular regulated kinase (ERK) phosphorylation and cytokine production induced by trypsin and PAR2-agonist using western blot and enzyme-linked immunosorbent assay (ELISA), respectively. Results: Treatment of trypsin or PAR2-activating peptide increased cell proliferation in a dose-dependent manner, and induced the activation of ERK1/2 in THP-1 cells. In addition, trypsin-induced cell proliferation was inhibited by pretreatment of an ERK inhibitor (pD98059) or trypsin inhibitor (SBTI). Moreover, PAR2 activation by trypsin increased the secretion of TNF-${\alpha}$ in THP-1 cells. Conclusion: There results suggest that P AR2 activation by trypsin-like serine proteases can induce cell proliferation through the activation of ERK in human macrophage and that PAR2 may playa crucial role in the cell proliferation and cytokine secretion induced by trypsin-like serine proteases.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.15
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• pp.6429-6436
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• 2014

Poly-ADP-ribosylation (PAR) is a post-translational modification of mainly chromosomal proteins. It is known to be strongly involved in several molecular events, including nucleosome-remodelling and carcinogenesis. In this investigation, it was attempted to evaluate PAR level as a reliable biomarker for early detection of cancer in blood lymphocyte histones. PAR of isolated histone proteins was monitored in normal and dimethylnitrosamine (DMN)-exposed mice tissues using a novel ELISA-based immuno-probe assay developed in our laboratory. An inverse relationship was found between the level of PAR and period of DMN exposure in various histone proteins of blood lymphocytes and spleen cells. With the increase in the DMN exposure period, there was reduction in the PAR level of individual histones in both cases. It was also observed that the decrease in the level of PAR of histones resulted in progressive relaxation of genomic DNA, perhaps triggering activation of genes that are involved in initiation of transformation. The observed effect of carcinogen on the PAR of blood lymphocyte histones provided us with a handy tool for monitoring biochemical or physiological status of individuals exposed to carcinogens without obtaining biopsies of cancerous tissues, which involves several medical and ethical issues. Obtaining blood from any patient and separating blood lymphocytes are routine medical practices involving virtually no medical intervention, post-procedure medical care or trauma to a patient. Moreover, the immuno-probe assay is very simple, sensitive, reliable and cost-effective. Therefore, combined with the ease of preparation of blood lymphocytes and the simplicity of the technique, immuno-probe assay of PAR has the potential to be applied for mass screening of cancer. It appears to be a promising step in the ultimate goal of making cancer detection simple, sensitive and reliable in the near future.

• Journal of the Korea Society for Simulation
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• v.21 no.3
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• pp.1-9
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• 2012

This paper proposes automatic precision approach radar (PAR) control system using digital signal to increase the safety of aircraft, and discrete event systems specification (DEVS) methodology is utilized to verify the proposed system. Traditionally, a landing aircraft is controlled by the human voice of a final approach controller. However, the voice information can be missed during transmission, and pilots may also act improperly because of incorrectness of auditory signals. The proposed system enables the stable operation of the aircraft, regardless of the pilot's capability. Communicating DEVS (C-DEVS) is used to analyze and verify the behavior of the proposed system. A composed C-DEVS atomic model has overall composed discrete state sets of models, and the state sequence acquired through full state search is utilized to verify the safeness and the liveness of a system behavior. The C-DEVS model of the proposed system shows the same behavior with the traditional PAR control system.

• Journal of Adhesion and Interface
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• v.13 no.1
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• pp.24-30
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• 2012

Morphological changes of polyarylate (PAR) fiber treated with formic acid and ultraviolet (UV) were observed by using a scanning electron microscope (SEM) and an atomic force microscope (AFM). The results were analysed by using root mean square (RMS) roughness. In addition, the chemical changes of surface was investigated using contact angle and the interfacial adhesive strength between PAR fiber and PEN (Polyethylene naphthalate) matrix was calculated using the Pull-out test results. As the acid treatment concentration and UV irradiation time increased, cracks and pores were produced on the PAR fiber surface. Due to the roughness increased, the contact angle was decreased. For this reason, RMS roughness of PAR fiber was increased and the interfacial adhesive strength between the PAR fiber and PEN matrix was improved. The increase of interfacial adhesive strength was responsible for the increase of surface area which have cracks and pores.

• Proceedings of the KIPE Conference
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• 2018.07a
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• pp.252-254
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• 2018

본 논문에서는 최근에 관심이 집중되고 있는 LED 조명 플리커의 건강에 대한 잠재적인 영향을 설명하고 IEEE PAR1789 committee에서 권장하는 실무 지침에 대하여 설명한다.

• Korean Journal of Clinical Laboratory Science
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• v.48 no.2
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• pp.74-81
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• 2016

Ureaplasma species can normally colonize in the bodies of healthy individuals. Their colonization is associated with various diseases including non-gonococcal urethritis, chorioamnionitis, neonatal meningitis, and prematurity. In 2012, the sum of the resistant and intermediate resistant rates of Ureaplasma spp. to ofloxacin and ciprofloxacin was 66.08% and 92.69%, respectively. DNA point mutations in the genes encoding DNA gyrase (topoisomerase II) and topoisomerase IV are commonly responsible for fluoroquinolone resistance. Each enzyme is composed of two subunits encoded by gyrA and gyrB genes for DNA gyrase and parC and parE genes for topoisomerase IV. In the current study, these genes were sequenced in order to determine the role of amino acid substitutions in Ureaplasma spp. clinical isolates. From December 2012 to May 2013, we examined mutation patterns of the quinolone resistance-determining region (QRDR) in Ureaplasma spp. DNA sequences in the QRDR region of Ureaplasma clinical isolates were compared with those of reference strains including U. urealyticum serovar 8 (ATCC 27618) and U. parvum serovar 3 (ATCC 27815). Mutations were detected in all ofloxacin- and ciprofloxacin-resistant isolates, however no mutations were detected in drug-susceptible isolates. Most of the mutations related to fluoroquinolone resistance occurred in the parC gene, causing amino acid substitutions. Newly found amino acid substitutions in this study were Asn481Ser in GyrB; Phe149Leu, Asp150Met, Asp151Ile, and Ser152Val in ParC; and Pro446Ser and Arg448Lys in ParE. Continuous monitoring and accumulation of mutation data in fluoroquinolone-resistant Ureaplasma clinical isolates are essential to determining the tendency and to understanding the mechanisms underlying antimicrobial resistance.