• 제목/요약/키워드: PAK

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반복된 후방 십자 인대 재건술 후 발생한 구획 증후군 및 심부 정맥 혈전증 (Compartment Syndrome and Deep Vein Thrombosis after Repetitive Posterior Cruciate Ligament Reconstruction)

  • 김진구;이수원;최홍준
    • 대한관절경학회지
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    • 제12권1호
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    • pp.58-62
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    • 2008
  • 후방 십자 인대 재건술은 신경혈관 합병증 발생 위험율이 높은 수술 방법이다. 하지만 후방 십자 인대 재건술 후 발생한 심부 정맥 혈전증 및 그와 관련된 구획증후군에 대한 보고는 없다. 본 교실에서는 후방 십자 인대 파열로 반복적인 수술을 시행 받은 환자에서 경골 inlay 방법을 이용한 후방 십자 인대 재재건술 후 발생한 신경혈관 합병증의 증례를 보고하고 이의 중요성에 대한 고찰을 하고자 한다.

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실록에 나타나는 15세기 태평관·모화관 건축과 관련 인물연구 (A Study on the Taepyeonggwan, Mohwagwan and the Architects Contrived these Architectures as Shown in The annals of the J oseon Dynasty of 15C)

  • 김버들;조정식
    • 건축역사연구
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    • 제25권4호
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    • pp.19-29
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    • 2016
  • This study is based on the 15th century's architecture Mohwagwan and Taepyeonggwan and the architects behind it. The results were as follows: First, inline with Ming dynasty's protocol, the King of Joseon marched with honor guard in front of his people. Therefore, the Joseon dynasty needed to match space was implemented and result in Mohwagwan and Taepyeonggwan. Second, King Taejong founded Mohwaru to share the role with Taepyeonggwan. He appropriately utilized Mohwaru as a place in manners before people enter the Seoul city wall. And He organized this architecture on the level of the palace. Third, Pak Jacheong was overseer the whole constructive process, from the selection of site, landscaping, construction, maintenance to civil engineering of Mohwaru. There are many difficulties, but he completed through the construction work owing to the protection of King Taejong. Forth, Hong Li worked with Pak Jacheong to build Taepyeonggwan and Mohwagwan from Taejong to Sejong. Supervisors in King Sejong times were required not only private capability but also understanding the Confucianism ritual. Hong Li was faithfully performed the role. Fifth, Sejong was recognized only an excellent ruler but he was also a great coordinator with a professional knowledge about architecture. These Sejong's action fully can be seen as an architect.

염기성 세균 배양을 위한 Steel Wool법과 Gaspak법의 비교 (Comparative Studies of Steel Wool Method and Gaspak Method for the Culture of Anaerobic Bacteria)

  • 정윤섭
    • 미생물학회지
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    • 제12권3호
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    • pp.131-137
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    • 1974
  • It is a well-known fact that an isolation of non-sporeforming anaerobes, considered normal flora in man ordinarily but causes serious infections sometimes, is a dificult procedure because of their great oxygen sensitivity. Among the many techniques employed in clinical laboratories, despite of its high expenses, the GasPak method has been most widely used because of its relative simplicity. On the other hand, the steel wool method has gained a good reputation recently. This technique makes it possible to treat individual plate so that any single specimen can be promptly cultured anaerobically. The procedure is quite simple and the expenses are negligible. In the present study it is to compare these two methods as to their efficiency of anaerobic cultivation using 13 VPI strains of non-sporeforming amaerobic bacteria. Among the 13 species the following 11, Bacteroides fragilis ss. fragilis, B. fragilis ss. thetaiotaomicron, propionibacterium acnes, Eubacterium limosum, E. lentum, peptococcus asaccharolyticus, Pc. prevotii, Pc. magnus, peptostreptococcus anaerobius, Ps. intermedius nad Veillonella parvula, grew well with the steel wool method whose colony numbers reaching 57 to 119% of those with GasPak method. The remaining two species, Fusobacterium nucleatum and F.necrophorum, did not grow well with the steel wool method showing the colony numbers were only 0.4% of those with GasPak method in the case of Fusobacterium nucleatum. In the case of Fusobacterium necrophorum, very few colonies developed even with a heavy inoculation. As to the size of colonies, there were no significant difference between these two methods.

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High-Performance Liquid Chromatographic Analysis of Chrysin Derivatives on A $Nova-Pak^{\circledR}C_{18}$ Column

  • Kim, Kyoung-Soon;Shin, Joon-Su;Park, You-Mie;Lee, Sanghyun;Kim, Yang-Bae;Kim, Bak-Kwang
    • Archives of Pharmacal Research
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    • 제25권5호
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    • pp.613-616
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    • 2002
  • A high-performance liquid chromatographic method has been developed for the separation and quantification of chrysin and synthetic chrysin derivatives (12 chrysin alkyl and 7 chrysin acyl derivatives). The chromatography was performed using a $Nova-Pak^{\circledR}C_{18}$ column. A RP-HPLC was performed by using a binary mixture (MeOH-10 mM H$_3$PO$_4$) as a mobile phase, and the column temperature was maintained at room temperature. A flow rate was 1.0 ml/min, and the effluent was monitored at a wavelenth of 280 nm. The retention times for chrysin acyl and alkyl derivatives were within 10 minutes and 20 minutes, respectively. The absolute recovery of samples were all over 96%. The detection limits were 0.1~18 ng at S/N = 3 ratio.

Signcryption을 이용한 안전한 인증된 키 교환 프로토콜 연구 (Secure Authenticated key Exchange Protocol using Signcryption Scheme)

  • 김락현;염흥열
    • 정보보호학회논문지
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    • 제16권4호
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    • pp.139-146
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    • 2006
  • 1997년 Yuliang Zheng에 의해 제안된 Signcryption은 서명과 암호 기법을 결합한 하이브리드 공개키 프리미티브로서 서명 기법 후 암호 기법을 각각 적용한 기법보다 계산 및 통신비용 측면에서 높은 효율성을 갖는 기법이다. 또한 PAK(Pass-word-Authenticated Key Exchange) 프로토콜은 사용자가 암기하거나 휴대하기 쉬운 짧은 길이의 패스워드를 기반으로 통신주체를 상호 인증하고, 결과적으로 안전한 통신을 위하여 충분히 큰 길이의 세션키를 분배하는 프로토콜이다. 본 논문에서는 PAK와 Signcryption의 특징을 이용하여 참여자의 비밀 정보를 이용한 상호 인증 및 안전한 통신을 위한 키 분배 프로토콜을 제안한다. 그리고 제안 프로토콜의 보안성을 증명하고 효율성을 비교한다.

Global Oil Prices and Exchange Rate: Evidence from the Monetary Model

  • ZAFAR, Sadaf;KHAN, Muhammad Arshad
    • The Journal of Asian Finance, Economics and Business
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    • 제9권1호
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    • pp.189-201
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    • 2022
  • The study empirically examines the impact of monetary fundamentals along with global oil prices on the Pak-rupee exchange rate using the monthly data over 2001-2020. Employing the cointegrating vector autoregressive with exogenous variables (VARX) and vector error correction model with exogenous variables (VECMX), the study analyzes the impact of domestic monetary fundamentals while considering the foreign variables as weakly exogenous. In order to account for the structural breaks in the data, the Lagrange multiplier (LM) unit root test with two structural breaks has been used (Lee & Strazicich, 2003). The empirical results reveal that the domestic and foreign monetary variables significantly explain the exchange rate movements in Pakistan both in the long run and in the short run. The dynamic properties of the monetary model of exchange rate have been analyzed using the persistence profile analysis and generalized impulse response functions (GIRFs). The results reveal that the responses of shocks to domestic monetary fundamentals are consistent with the predictions of the monetary model of the exchange rate. Furthermore, being a net oil importer, a rise in global oil prices significantly depreciated the Pak-rupee exchange rate over the period of study. The global financial crisis (GFC) and pandemic (COVID-19) were also found to cause the Pak-rupee exchange rate depreciation.

Developing Innovation Product of Meals Ready-to-Eat (MRE) for Emergency Supply Distribution to Disaster Victims

  • Nattapat THANAPANICHAPAN;Duangrat TANDAMRONG
    • 유통과학연구
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    • 제21권10호
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    • pp.31-38
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    • 2023
  • Purpose: Each emergency event has several aspects of impact, including the effects on lives, economy, and the environment. Additionally, the damage to infrastructure systems can contribute to food shortages during a disaster. Research design, data and methodology: This research aims to study ready-to-eat food innovations that influence the consumer buying behavior of emergency victims and to develop ready-to-eat meal innovations to help emergency victims with an emphasis on research and innovation of Meals Ready-to-Eat (MREs). Results: A questionnaire was employed to collect the data from people living in Pak Kret Municipality, Nonthaburi Province. Pak Kret Municipality is administered under five subdistricts, covering 34 villages in Pak Kret, Bang Phut, Ban Mai, Bang Talat, and Khlong Kluea. Multiple correlation and multiple regression techniques were used to analyze the data. The study revealed that integrated marketing communication, unique proposition, customer orientation, and product variety influenced consumer buying behavior of MREs to help emergency victims at a statistically significance level of 0.05. Conclusions: The results indicate that, in emergency situations, MREs play a crucial role. When infrastructure and essential services are disrupted, MREs are a convenient and long-lasting option for providing timely assistance during emergencies.

천연물 유래 물질이 감염성 질환에 미치는 영향과 효능 (Effects and Efficacy of Natural Product on Infectious Diseases of pseudomonas aeruginosa)

  • 박지원
    • 한국자원식물학회:학술대회논문집
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    • 한국자원식물학회 2020년도 추계국제학술대회
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    • pp.3-13
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    • 2020
  • Pseudomonas aeruginosa is a ubiquitous gram-negative bacterium causing serious infections. The P. aeruginosa T3SS is a syringe-like apparatus on the bacterial surface, with 4 effector toxins: ExoS, ExoT, ExoY, and ExoU. Here, we investigated the effect of ExoS and ExoT of the T3SS of P. aeruginosa K strain (PAK). The type three secretion system (T3SS) is a major virulence system of Pseudomonas aeruginosa (P. aeruginosa). The effector protein Exotoxin S (ExoS) produced by P. aeruginosa is secreted into the host cells via the T3SS. For the purpose of screening the inhibitors with regard to ExoS secretion, we developed the sandwich-type enzyme-linked immunosorbent assay (ELISA) system. PAK clinical strains induce proinflammatory cytokine production through the T3SS, and this involves NF-κB activation in pneumonia mouse models. We tried to confirm the role of the NF-κB transcription factor in ExoS- and ExoT-induced pneumonia mouse models. pro-inflammatory cytokines induction in response to ExoS and ExoT infection relied on NF-κB activation. Our findings highlight the roles of natural poduct in inhibiting proinflammatory cytokine expression during ExoS and ExoT exposure in PAK infections, paving the way for a novel therapeutic approach for the treatment of pulmonary infections.

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발효과정에서 생성되는 발효유제품의 안식향산 함량 수준 평가 (Evaluation of Benzoic Acid Level of Fermented Dairy Products during Fermentation)

  • 임상동;박미선;김기성;유미영
    • 한국축산식품학회지
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    • 제33권5호
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    • pp.640-645
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    • 2013
  • 본 연구는 발효과정 중 생성되는 발효유제품의 안식향산을 조사함으로써 축산식품관리 정책의 기초자료로 활용하기 위하여 실시하였다. 축산물의 가공기준 및 성분규격의 축산물 시험법 중 전처리 방법인 Sep-Pak을 이용한 분석방법과 자동증류장치를 이용한 분석방법 중 1개를 택일하기 위하여 유제품의 회수율을 측정한 결과 커다란 차이가 없음에 따라 전처리 시간이 짧은 Sep-Pak을 이용한 분석방법을 선정하였다. Sep-Pak법의 유효성 검증으로 안식향산의 검량선은 $R^2$ = 0.999로 양호한 직선성을 나타냈으며, 검출한계는 0.058 mg/kg, 정량한계는 0.176 mg/kg을 보였다. 완제품에서 검출된 발효유를 대상으로 공정 단계별로 안식향산을 분석한 결과 스타터를 첨가한 이후 단계에서 2.28-10.48 mg/kg 수준이었고 첨가제(시럽)에서는 검출되지 않았으며, 시중 유통 중인 발효유는 0-16.5 mg/kg으로 나타났다. 치즈의 경우 카멤베르 치즈는 커드형성 후, 가공치즈는 원료치즈에서 영향을 많이 받는 것으로 나타났고, 시중 유통 중인 자연치즈는 0-4.2 mg/kg, 가공치즈는 0-20.8 mg/kg으로 나타났다. 이러한 결과를 토대로 원료, 제조과정 중 및 완제품 전과정에서 발생될 수 있는 자연유래 안식향산을 일관성 있고 체계적으로 관리할 수 있는 기초자료로 활용할 것으로 사료된다.

Yield and Nutritional Quality of Several Non-heading Chinese Cabbage (Brassica rapa var. chinensis) Cultivars with Different Growing Period and Its Modelling

  • Kalisz, Andrzej;Kostrzewa, Joanna;Sekara, Agnieszka;Grabowska, Aneta;Cebula, Stanislaw
    • 원예과학기술지
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    • 제30권6호
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    • pp.650-656
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    • 2012
  • The aims of the experiment, conducted over three years in the Central Europe field conditions, were (1) to investigate the effect of growing period (plantings in the middle and at the end of August: $1^{st}$ and $2^{nd}$ term, respectively) on yield and chemical composition of the non-heading Chinese cabbage (Brassica rapa var. chinensis) cultivars 'Taisai', 'Pak Choy White', and 'Green Fortune', and (2) to develop regression models to evaluate the changes in crop yields as a function of weather conditions. A highest marketable yield was obtained from 'Taisai' (65.71 and 77.20 $t{\cdot}ha^{-1}$), especially in the $2^{nd}$ term of production. Low yield, observed for 'Pak Choy White' was due to its premature bolting. Almost 39% ($1^{st}$ term) and 70% ($2^{nd}$ term) of plants of this cultivar formed inflorescence shoots before harvest. The highest dry matter level was observed in the leaf petioles of 'Taisai', while 'Green Fortune' was the most abundant of carotenoids and L-ascorbic acid. The content of soluble sugars was the lowest for 'Pak Choy White'. In a phase of harvest maturity, more of the analyzed constituents were gathered by plants from earlier plantings, and differences were as follows: 4.7% (dry matter), 26.3% (carotenoids) and 22.1% (L-ascorbic acid), in comparison to $2^{nd}$ term of production. Significant increase of soluble sugars level was observed for plants from later harvest. The regression model for marketable yield of Chinese cabbage cultivar 'Taisai' as a function of maximum air temperature can predict the yield with accuracy 68%. The models for yield or bolting of 'Pak Choy White', based on extreme air temperatures and sunshine duration, were more precise (98%). It should be pointed out that Taisai could be recommended for later growing period in Central Europe conditions with regard to maximum yield potential. 'Green Fortune' was notable for its uniform yielding. To obtained plants of higher nutritional value, earlier time of cultivation should be suggested. Described models can be successfully applied for an approximate simulation of Chinese cabbage yielding.