• Journal of Chest Surgery
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• v.43 no.5
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• pp.499-505
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• 2010

Background: There have been several reports using animal experiments that CD1-restricted T-cells have a key role in tumor immunity. To address this issue, we studied the expression of markers for CD1c+ myeloid dendritic cells (DCs) isolated from peripheral blood in the clinical setting. Material and Method: A total of 24 patients with radiologically suspected or histologically confirmed lung cancer who underwent pulmonary resection were enrolled in this study. The patients were divided according to histology findings into three groups: primary adenocarcinoma of lung (PACL), primary squamous cell carcinoma of lung (PSqCL) and benign lung disease (BLD). We obtained 20 mL of peripheral venous blood from patients using heparin-coated syringes. Using flow-cytometry after labeling with monoclonal antibodies, data acquisition and analysis were done. Result: The ratio of CD1c+CD19- dendritic cells to CD1c+ dendritic cells were not significantly different between the three groups. CD40 (p=0.171), CD86 (p=0.037) and HLA-DR (p=0.036) were less expressed in the PACL than the BLD group. Expression of CD40 (p=0.319), CD86 (p=0.036) and HLA-DR (p=0.085) were less expressed in the PACL than the PSqCL group, but the differences were only significant for CD86. Expression of co-stimulatory markers was not different between the PSqCL and BLD groups. Expression of markers for activated DCs were dramatically lower in the PACL group than in groups with other histology (CD40 (p=0.005), CD86 (p=0.013) HLA-DR (p=0.004). Conclusion: These results suggest the possibility that CD1c+ myeloid DCs participate in control of the tumor immunity system and that low expression of markers results in lack of an immune response triggered by dendritic cells in adenocarcinoma of the lung.

• Journal of Korean Society of Environmental Engineers
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• v.32 no.8
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• pp.774-779
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• 2010

The experimental results for the analysis of aluminum hydrolysis species with PACls (polyaluminum chloride) prepared by different basicity (r value) showed that monomeric Al species were reduced while polymeric Al species were increased with an increase in basicity for PACls. The PACl with 2.2 of r value contained the highest amount of polymeric Al species. According to the experimental results for the phosphorus removal, the alum and PACl (r=0), which consisted of mainly monomeric Al species, were the most effective for phosphorus removal. Therefore, it was concluded that the Al coagulant containing higher amount of monomeric or lower molecular Al species would be more beneficial for phosphorus removal.

• Journal of Korean Society of Environmental Engineers
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• v.35 no.7
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• pp.495-502
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• 2013

This work was performed to investigate proper condition of coagulation treatment as UF process pretreatment that consider UF permeate flux and residual Al concentration. The coagulant used an alum as $Al_2(SO_4)_3{\cdot}16H_2O$ and PACl (r = 1.5) made this study. The experiment was tested in adjusting conditions such as alum dose, flocculation time and coagulation pH of seawater. Consequently, higher coagulant dose lead to elevation of UF permeate flux while residual aluminium also increased in condition of pH 8.0. The most suitable condition which has a good permeate flux and low residual aluminium, in this works, was coagulant dose of 0.7 mg/L (as Al, alum) and 1.2 mg/L (as Al, PACl) and coagulation pH 6.5. In addition, applying the flocculation time with 1.2 mg/L of PACI reduced. The flocculation time reduced UF permeate flux in using alum.

• Journal of Korean Society of Water and Wastewater
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• v.32 no.1
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• pp.47-53
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• 2018

This study investigated phosphorus removal from secondary treated effluent using coagulation-membrane separation hybrid treatment to satisfy strict regulation in wastewater treatment. The membrane separation process was used to remove suspended phosphorus particles after coagulation/settlement. Membrane separation with $0.2{\mu}m$ pore size of micro filtration membrane could reduce phosphorus concentration to 0.02 mg P/L after coagulation with 1 mg Al/L dose of polyaluminum chloride (PACl). Regardless of coagulant, the residual concentration of phosphorus decreased as the dose increased from 1.5 to 3.5 mg Al/L, while the target concentration of 0.05 mg P/L or less was achieved at 2.5 mg Al/L for the aluminum sulfate (Alum) and 3.5 mg Al/L for PACl. Moreover, alum showed better membrane flux as make bigger particles than PACl. Alum showed a 40% of flux decrease at 2.5 mg Al/L dose, while PACl indicated a 50% decrease of membrane flux even with a higher dose of 3.5 mg Al/L. Thus, alum was more effective coagulant than PACl considering phosphorus removal and membrane flux as well as its dose. Consequently, the coagulation-membrane separation hybrid treatment could be mitigate regulation on phosphorus removal as unsettleable phosphorus particles were effectively removed by membrane after coagulation.

• Membrane and Water Treatment
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• v.13 no.1
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• pp.15-20
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• 2022

The continuous industrial growth increases the volume of pollutants discharged into the water, which induces Cyanobacteria in the receiving bodies. The removal of various cyanobacteria such as Microcystis, Anabaena, and Oscillatoria was explored to analyze their removal characteristics using different chemical and mineral coagulants. The chemical coagulants, including poly aluminium chloride (PACl), Alum, and mineral coagulants such as Loess and Illite, were tested to remove selected cyanobacteria. Results indicated that the removal rate increased with coagulant dosage regardless of the type of coagulant. The removal of selected cyanobacteria using chemical coagulant was found in the order: Microcystis > Anabaena > Oscillatoria. The PACl coagulant showed the most efficient removal rate for Microcystis, Anabaena, Oscillatoria. Removal rate of Microcystis conducted by PACl showed 92% at 100,000 cells/mL and 98.4% at 1,000,000 cells/mL whereas Illite showed lower 70% and Loess showed lower 50% in both 100,000 cells/mL and 1,000,000 cells/mL. The removal rate of Anabaena and Oscillatoria by PACl and Alum was higher 80%, while the other coagulants exhibited lower than 75% at 1,000,000 cells/mL. The removal rate of Oscillatoria by PACl was 80.1%, while the other coagulants exhibited lower than 70% at 1,000,000 cells/mL. Moreover, the mineral coagulants showed better removal efficiency at a higher concentration than low concentration during experiments. Therefore, removing cyanobacteria from water streams can be improved through coagulation by selecting a specific coagulant for a particular type of algae.

• Journal of Korean Society of Water and Wastewater
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• v.12 no.3
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• pp.107-117
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• 1998

In order to removal turbidity at high turbidity, this study was carried to evaluate the coagulants(Alum, PACl, PACS) that was suited the characteristics of raw water in water treatment plants and to determinate the optimum method of lime feed. When the optimum coagulant was selected the organic matter removal was also investigated as $UV_{254}$. PACl, lime first feed had the highest turbidity removal efficiency rate as above 99.1% and then $UV_{254}$ removal rate was obtained over than 88.0%. If you had the necessary of the lime feed, among the method of lime feed time interval feed largely was improved than simultaneous feed. Also, lime feed dose had about 1/5 of coagulants dose in case of Alum and PACl, but always PACS should be considerated lime dose.

• Journal of Korean Society of Environmental Engineers
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• v.22 no.3
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• pp.441-451
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• 2000

Sludge produced from water treatment plants contains plenty of aluminum due to addition of coagulants, polyaluminum chloride(PACI) which has been widely used in most of water treatment plants. however. the whole of PACI is imported from other countries. In this research. the effective methods for recycling PACI from sludge of water treatment plants were developed and evaluated. Aluminum chloride hexahydrate($AlCl_3{\cdot}6H_2O$) was obtained by sparging HCl gas aluminum extracted from sludge using hydrochloric acid (HCI). This aluminum chloride hexahydrate was solidified by decomposition at $180^{\circ}C$. and dissolved in water to produce PACI. The optimum extraction rate was obtained at the condition of 10 minutes of reaction time. $105^{\circ}C$ of reaction temperature. 27.65%(W/W) of HCI concentration. The KS experiment proved that manufactured aluminum chloride hexahydrate was 98.7% degree and the recycled PACI coagulants agreed with the KS standard. The optimum temperature of decomposition was $180^{\circ}C$ and the basicity of the PACI was decided upon the extent of decomposition The compared experiments between purchased coagulant and manufactured coagulant presented that both coagulants had same performance for turbidity, DOC, $UV_{254}$ absorbance. and chlorophyll-a.

• Membrane Journal
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• v.23 no.6
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• pp.460-468
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• 2013

This study reviewed optimum dosage rate of coagulant and ability to remove dissolved organic carbon without sedimentation in conventional water purification plant. It was confirmed that floc formated by pre-treatment process was broken by impeller of booster pump. Optimum dosage rate of coagulant was 4 mg/L (as PACl 17%) for floc formation through blend, coagulation and after passing through the pump when turbidity of raw water was less than 10 NTU. And average removal rate of dissolved organic carbon was 43% at that time. Maximum removal rate of dissolved organic carbon was 48%, even though coagulation rate was increased gradually until 8 mg/L (as PACl 17%). So removal rate of dissolved organic carbon is not much improved even if dosage rage of coagulant increase. TMP of PVDF (polyvinylidene flouride) pressurized MF process without pre-treatment operated at 0.54 bar and TMP of PVDF pressurized MF process with pre-treatment operated at 0.41 bar.

• Journal of Korean Society of Water and Wastewater
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• v.13 no.2
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• pp.66-73
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• 1999

This study was carried out to derive the removal characteristics of target materials(DOC and turbidity) during the coagulation process after the injection of coagulants(PACl and FeCl3). Used apparatus were a jar test and a pilot plant. A great portion of DOC among the total removed DOC was achieved at the slow mixing process among the coagulation process. The ranges of removed DOC and optimum pH for each coagulant were 0.45~1.47mg/l and 6.0~6.5 by PACl, and 0.97~2.61mg/l. and 5.0~5.5 by FeCl3, respectively. Both of coagulants showed little increase of DOC removal above coagulant dosage 20mg/l Molecular weight distribution(MWD) of removed DOC was measured by get filtration(GF) technique. The MWD variation by gel filtrationin(GF) for removed DOC in the coagulation process were as follows; for raw water, the percentages of each MWD for total area were < MW 6,500 25.5%, MW 6,500~66,000 67.1%, and > MW 66,000 7.4%. For the same coagulant dosage(12mg/l), the percentages of each MWD for total area by PACl were < MW 6,500 20.5%, MW 6,500~66,000 48.7%, and > MW 66,000 9.1%, and those of FeCl3 were MW 66,000 18.2%. For each coagulant, the removal percentage of MW 6,500~66,000 occurred a little, but at a part of

• Journal of Korean Society of Water and Wastewater
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• v.18 no.2
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• pp.128-136
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• 2004

The overall objective of this research was to find out the role of rapid mixing conditions in the species of hydrolyzed Al(III) formed by different Al(III) coagulants. When an Al(III) salt is added to water, monomers, polymers, or solid precipitates may form. Different Al(III) coagulants (alum and PACl) show to have different Al species distribution over a rapid mixing condition. During the rapid mixing period, for alum, formation of dissolved Al(III) (monomer and polymer) increases, but for PACl, precipitates of $Al(OH)_{3(s)}$. increases rapidly. Also, for alum, higher mixing speed favoured Al(III) polymers formation over precipitates of $Al(OH)_{3(s)}$ but for PACl, higher mixing speed formed more precipitates of $Al(OH)_{3(s)}$. At A/D and sweep condition, both $Al(OH)_{3(s)}$ and dissolved Al(III) (monomer and polymer) exist, concurrent reactions by both mechanism appear to cause simultaneous precipitation.