• Title/Summary/Keyword: P242

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Physiological activities of Lespedeza cuneata extracts (야관문 추출물의 생리 활성)

  • Park, Hye-Mi;Hong, Joo-Heon
    • Food Science and Preservation
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    • v.21 no.6
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    • pp.844-850
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    • 2014
  • This study was conducted to examine the physiological activities of Lespedeza cundata extracts. The extraction yield of 50% ethanol extract (17.60%) was higher than that of hot water extract (12.60%). The total phenolic and total flavonoid contents of the 50% ethanol extract were 242.26 mg/g and 160.73 mg/g, respectively. The DPPH radical scavenging activities of the hot water and 50% ethanol extracts were 92.07% and 96.38%, respectively. The superoxide radical scavenging activities of hot water and 50% ethanol extracts on $250{\sim}1,000{\mu}g/mL$ were 54.89~85.68% and 44.50~94.46%, respectively. The tyrosinase inhibition activity of the 50% ethanol extract at $1,000{\mu}g/mL$ (63.31%) was the highest. The nitrite scavenging activity of the 50% ethanol extract was higher than that of the hot water extract. The nitric oxide production of 50% ethanol extract ($7.15{\sim}20.61{\mu}M$) improved with an increase in the treatment concentration. The hot water and 50% ethanol extracts at $1,000{\mu}g/mL$ inhibited the proliferation of the cancer cell lines A549, HeLa, Hep3B, and Sarcoma180. There results suggest that the 50% ethanol Lespedeza cuneata extracts may be useful as a functional food material in the food industry.

Complications Leading Reoperation after Gastrectomy in Patients with Gastric Cancer: Frequency, Type, and Potential Causes

  • Yi, Ha Woo;Kim, Su Mi;Kim, Sang Hyun;Shim, Jung Ho;Choi, Min Gew;Lee, Jun Ho;Noh, Jae Hyung;Sohn, Tae Sung;Bae, Jae Moon;Kim, Sung
    • Journal of Gastric Cancer
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    • v.13 no.4
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    • pp.242-246
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    • 2013
  • Purpose: Reoperations after gastrectomy for gastric cancer are performed for many types of complications. Unexpected reoperations may cause mental, physical, and financial problems for patients. The aim of the present study was to evaluate the causes of reoperations and to develop a strategic decision-making process for these reoperations. Materials and Methods: From September 2002 through August 2010, 6,131 patients underwent open conventional gastrectomy operations at Samsung Medical Center. Of these, 129 patients (2.1%) required reoperation because of postoperative complications. We performed a retrospective analysis of the patients using an electronic medical record review. Statistical data were analyzed to compare age, sex, stage, type of gastrectomy, length of operation, size of tumor, and number of lymph node metastasis between patients who had been operated and those who had not. Results: The variables of age, sex, tumor stage, type of gastrectomy, length of operation, and number of lymph node metastases did not differ between the 2 groups. However, the mean tumor size in the reoperation group was greater than that in the non-reoperation group ($5.0{\pm}3.7$ [standard deviation] versus $4.1{\pm}2.9$, P=0.007). The leading cause of reoperation was surgical-site infection (n=49, 0.79%). Patients with intra-abdominal bleeding were operated on again in the shortest period after the initial gastrectomy ($6.3{\pm}4.2$ days). Patients with incisional hernia were not reoperated on until after $208.3{\pm}81.0$ days, the longest postoperative period. Conclusions: Tumor size was the major variable leading to reoperation after gastrectomy for gastric cancer. The most common complication requiring the reoperation was a surgical site-related complication.

Diurnal fluctuations of vision in myopes (근시안의 일일 시럭변동에 관한 연구)

  • Park, Sang-Chul;Sung, A-Young;Kim, Tae-Hyun;Kim, Douk-Hoon
    • Journal of Korean Ophthalmic Optics Society
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    • v.10 no.1
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    • pp.35-40
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    • 2005
  • Subjective and objective visions were measured on young adults(mean 21 yrs, 126 eyes) who were free of any ocular diseases and laser surgery and none wore contact lenses. The aim of this study was to investigate the diurnal variation of vision through subjective and objective measurements. Subjective visual acuity were measured at 5 m three times a day, morning(8:00 AM-10:00 AM), noon(12:00 PM-2:00 PM) and afternoon(4:00 PM-6:00 PM). The instrument used for objective refraction right after visual acuity measurement was Nvision-K 5001(shin-nippon) which unique in being able to disregard subject's accommodation because of its unrestricted viewing conditions. Also, we measured that three times and then calculated the average values. The result showed that an average subjective visual acuity in the morning, noon, afternoon were 0.256(${\pm}0.263$), 0.266(${\pm}0.276$), 0.242(${\pm}0.249$) respectively. Average spherical equivalent power in objective refraction of right eyes showed -3.416 D(${\pm}2.907$), -3.359 D(${\pm}2.735$), -3.297 D(${\pm}2.709$) respectively and dioptric power was decreased from morning to afternoon. Vision changed throughout the day in both subjective and objective measurements nevertheless its variations were statistically insignificant(p<0.05). Therefore it does not seem to matter of time for either visual acuity test or refraction.

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Comparative Evaluation of Cardiac Output using Echocardiography in Beagle Dogs (비글견에서 심초음파를 이용한 심박출량 측정에 관한 비교 연구)

  • Park, Kitae;Yeon, Seongchan;Lee, Heechun
    • Journal of Veterinary Clinics
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    • v.29 no.5
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    • pp.384-390
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    • 2012
  • Echocardiographic measurements of cardiac output, including the modified Simpson's method, Automated Contour Tracking(ACT) method, and left ventricular outflow method are well described methods of evaluating cardiac function due to its reliability and the benefits of its non-invasive technique in human medicine. The purpose of this study was to evaluate the accuracy of an echocardiography estimate of cardiac output in isoflurane-anesthetized beagle dogs and was to compare the ACT method to the other methods used in measurement of cardiac output. In healthy beagle dogs, cardiac output results by echocardiography estimate methods showed an excellent correlations with those by the thermodilution method (The modified Simpson's method : r = 0.815, $r^2=0.665$, y = 0.434x + 0.311 ; ACT method : r = 0.86, $r^2=0.748$, y = 0.391x + 0.242 ; ventricular outflow method : r = 0.691, $r^2=0.478$, y = 0.593x + 0.242). Among the results obtained, the ACT method showed the highest correlation coefficient. In conclusion, our study demonstrated that echocardiography estimate methods did not prove to be suitable in accurately measuring absolute cardiac output values but showed an excellent correlation with thermodilution method. Therefore, by using the measurement of cardiac output as supplemental data, echocardiography estimate methods can be used for detection and correction of hemodynamic disturbances during emergency and anesthesia in veterinary practice.

Structural Equation Modeling Based on PRECEDE Model for the Quality of Life in the Elderly with Dementia in Rural Area (농촌지역 치매노인의 삶의 질 구조모형 - PRECEDE 모형 기반)

  • Mi-Soon, Song;Hyun-Li, Kim
    • Journal of agricultural medicine and community health
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    • v.47 no.4
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    • pp.242-254
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    • 2022
  • Purpose: This study was designed to test structural equation modeling of the quality of life of elderly diagnosed dementia living in the community in order to provide guidelines for development of intervention and strategies to improve their quality of life. Methods: The participants in the study were elderly who visited the public health center in C rural between May 30 and september 15, 2017. Data collection was carried out through one-on-one interviews. Demographic factors, knowledge, Attitude, Self-Efficacy, social support, accessibility, request for Information, health practice, depression, subjective memory complaints, dependence scale and quality of life were investigated. Results: The final analysis included 192 elderly. Fitness of the hypothesis model was appropriate(χ2=192.89, p=.000, GFI=0.90, SRMR=0.08, NNFI=0.94, CFI=0.95, PNFI=0.72, RMSEA=0.07). Depression, subjective memory complaints and dependence were found to be significant explaining varience in quality of life. Social support, dementia preventive behavior and health practice had an indirect effect on the quality of life. Conclusions: To improve the quality of life of elderly diagnosed dementia living in the community, comprehensive interventions are necessary to manage knowledge, attitude, self-efficacy, social support, health practice, depression, subjective memory complaints and dependence that can contribute to enchance the quality of life of elderly diagnosed dementia living in the community.

Geochemical Characteristics on Geological Groups of Stream Sediment in the Boseong-Hwasun Area, Korea (보성-화순지역 하상퇴적물에 대한 지질집단별 지구화학적 특성)

  • Park, Young-Seog;Kim, Jong-Kyun
    • Journal of the Korean earth science society
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    • v.32 no.7
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    • pp.707-718
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    • 2011
  • We study the natural background and geochemical characteristics on geological groups of stream sediment in the Boseong-Hwasun area. We collected 186ea stream sediment samples along the primary channels and dried them naturally in laboratory. The contents of major, trace and rare earth elements were determined by XRF, ICP-AES and NAA analysis methods. In order to know the natural background and geochemical characteristics of geological groups, we classified the studied area into granitic gneiss (GGn) area and porphyroblastic gneiss (PGn) area. The contents range of major elements for GGn area is $SiO_2$ 45.5-73.09 wt.%, $Al_2O_3$ 12-20.76 wt.%, $Fe_2O_3$(T) 3.72-8.85 wt.%, $K_2O$ 2.38-4.2 wt.%, MgO 0.75-2.77 wt.%, $Na_2O$ 0.78-1.88 wt.%, CaO 0.27-2.1 wt.%, $TiO_2$ 0.56-1.72 wt.%, $P_2O_5$ 0.06-0.73 wt.% and MnO 0.03-0.95 wt.%, and for PGn area it is $SiO_2$ 43.74-70.71 wt.%, $Al_2O_3$ 11.54-25.05 wt.%, $Fe_2O_3$(T) 3.44-13.46 wt.%, $K_2O$ 2.08-3.86 wt.%, MgO 0.65-2.99 wt.%, $Na_2O$ 0.63-1.7 wt.%, CaO 0.35-2.07 wt.%, $TiO_2$ 0.68-4.17 wt.%, $P_2O_5$ 0.1-0.31 wt.% and MnO 0.07-0.33 wt.%. The contents range of hazard elements for GGn area is Cr 41.7-242 ppm, Co 7.6-25.1 ppm, Ni 12-61 ppm, Cu 10-47 ppm, Zn 48.5-412 ppm, Pb 17-215 ppm, and for PGn area, it is Cr 29.6-454 ppm, Co 5.9-53.7 ppm, Ni 8.7-287 ppm, Cu 6.4-134 ppm, Zn 43.6-370 ppm, Pb 15-37 ppm area. There is a good correlation between Cr and MgO and Co among $Al_2O_3$, $Fe_2O_3$(T), MgO and Ni among $Fe_2O_3$(T), CaO, MgO whereas Cu, Zn and Pb have a low correlation for major elements in GGn area. Generally Cr, Co, Ni, and Cu have a good correlation with major elements, but a low correlation with Zn and Pb in PGn area.

Quality Characteristics of Seasoned Pork with Water Extracts of Allium hookeri Root during Storage (Allium hookeri 뿌리 열수 추출물을 첨가한 양념돈육의 저장 중 품질 특성)

  • Park, Min-Young;Ly, Sun Yung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.44 no.2
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    • pp.242-249
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    • 2015
  • This study examined the antioxidant and antimicrobial activities of 70% ethanol extracts and water extracts of Allium hookeri root. We evaluated the effects of water extracts of A. hookeri root on storage of seasoned pork added with water extracts at $4^{\circ}C$ for 21 days in order to evaluate its potential as a functional food material. A. hookeri root water extracts displayed antioxidant activities (total polyphenol content and DPPH and ABTS radical scavenging activities) that were superior to those of 70% ethanol extracts. The 70% ethanol extracts and water extracts of A. hookeri root showed antimicrobial activities against food-borne Staphylococcus aureus bacteria that were about 1/400 times greater than that of vancomycin. Chemical composition analysis was conducted on pork seasoned with sauce containing 5%, 10%, and 15% water extracts. Moisture and crude ash contents significantly decreased as the amount of water extracts increased (P<0.05), and the highest crude protein content was in the 10% group. Acidity of seasoned pork increased proportionally in the early stages of storage, whereas it significantly decreased as the amount of water extracts increased after day 12 (P<0.05). Although the total number of bacteria in seasoned pork continuously increased during storage, growth of bacteria was significantly restricted as level of A. hookeri root water extracts increased (P<0.05). In the sensory evaluation, pork seasoned with 10% A. hookeri root water extracts showed the highest scores for taste, texture, and overall acceptance (P<0.05). In summary, A. hookeri water extracts display antioxidant and antimicrobial activities that can improve quality characteristics of seasoned pork and have potential as natural preservatives to restrict bacteria growth. Regarding the amount of extracts, 10% was determined to be the most appropriate level to minimize changes in seasoned pork during storage and improve sensory quality.

Studies on the Petroleum hydrocarbon-utilizing Microorganisms(Part 1) -On the Production of Protein from the Yeast-cell- (석유(탄화수소) 이용미생물에 관한 연구(제 1보) -효모세포에 의한 석유로부터 단백질 생성에 관하여-)

  • Lee, Ke-Ho;Shin, Hyun-Kyung
    • Applied Biological Chemistry
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    • v.13 no.1
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    • pp.43-50
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    • 1970
  • To study the productivity of single cell protein from the petroleum hydrocarbon utilizing yeasts, 242 soil samples, such as oil soaked soil of gas stations and garage, coal, farm soil, and sewage, from 135 places in Korea were collected. From these samples 468 yeast strains which utilize petroleum hydrocarbon as a sole organic carbon source were isolated and identified by observing the growth rates. For the identified strains optimum culture conditions were determined and analysis of cell components were performed. 1. 90.8% of petroleum hydrocarbon utilizing yeast strains were found from oil soaked soil and about 10% from coal, farm soil and sewage etc. 2. The yeast strain of the highest cell productivity was isolated from oil soaked soil and was identified as Candida curvata HY-69-19. 3. The optimum culture conditions for the selected yeast strain were found to be pH 5.0, $28^{\circ}C$ and affluent aerated state. 4. Candida curvata HY-69-19 was found to utilize favorably the heavy gas oil fractionated at above $268.9^{\circ}C$ as carbon source and urea as inorganic nitrogen source. 5. The growth curve of this strain on heavy gas oil medium showed that the yeast has a lag phase up to 18 hours and logarithmic growth phase between 24 to 42 hours. Generation time was found to be between 3.8 and 4.5 hours during the logarithmic growth phase. 6. About 300 mg dried cells per heavy gas oil was harvested under the culture conditions of adjusted pH to 5.0 at time intervals of 6 hours for 54 hours and heavy gas oil urea for shaking culture medium. 7. Chemical composition of the yeast cell was found to be 40.25%, 14.81%, 24.32% and 10.63% for crude protein, crude lipid, carbohydrate and ashes, respectively.

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Component and Quality Characteristics of Powdered Green Tea Cultivated in Hwagae Area (화개지역 녹차분말의 성분 분석 및 품질특성)

  • Park Chan-Sung
    • Food Science and Preservation
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    • v.12 no.1
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    • pp.36-42
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    • 2005
  • The purpose of this study was to investigate the component and quality characteristics of green tea. Four kinds of green tea powder obtained from Hwagae area were evaluated the component of carbohydrates, protein crude fat and crude ash. Also the content of ascorbic acid, minerals and polyphenols in green tea powder were evaluated. Quality characteristics of green tea powder was evaluated by Hunter's colur value and sensory evaluation. Green tea was composed of $9.2\~11.8\%$ of moisture, $4.9\~6.1\%$ of crude ash, $5.2\~6.1\%$ of crude fat, $22.5\~26.4\%$ of protein and $50.4\~55.1\%$ of cabohydrates. The content of total ascorbic acid in green tea powder was $312\~392mg/100g$ and dehydiuascorbic acid was $157\~176mg/100g$. The contents of minerals in green tea powder sodium was $340\~580mg/100g$, magnesium was $242\~320mg/100g$, potassium $223\~278mg/100g$ me calcium $145.7\~238.7mg/100g$. Polyphenol content of green tea powder was $7.8\~9.3\%$ which was the highest in A and the lowest in B. Hunters color values of green tea, lightness(L) was $52.3\~69.6$, redness(a) was $0.11\~-5.61$, yellowness(b) was $14.23\~23.34$, which were better in green tea C and D than green tea A and B. From sensory evaluation of green tea powders, green tea D obtained the significant highest scores in color, flavor and overall quality(p<0.05) and followed by green tea C, Green tea powder C and D which have high levels of protein and ascorbic acid were evaluated as good quality in color and sensory evaluation.

Clinical significance of CA125 level in tuberculous pneumonia (결핵성 폐렴에서의 CA125측정의 임상적 의의)

  • Choi, Soo-Jeon;Kim, Young-Ho;Yum, Ho-Kee;Kim, Ju-In;Lee, Bong-Choon;Kim, Jeong-Sook
    • Tuberculosis and Respiratory Diseases
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    • v.43 no.2
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    • pp.159-163
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    • 1996
  • Background : In case of tuberculous pneumonia, differentiation from bacterial lobar pneumonia is sometimes very difficult because clinical symptoms, signs and radiological images are very similar. So we investigated the usefulness of CA125, which is known to increase in tuberculous diseases, in differential diagnosis between tuberculous pneumonia (TBPN) and community acquired bacterial lobar pneumonia (LP). Methods : Serum CA125 level was measured in 20 patients with TBPN (female 12 male 8 : mean age 36.1 years) and 14 patients with LP (female 5 male 9 : mean age 45.1 years) by radioimmunoassay (Centocor(R) CA125 RIA kit). Results : 1) The serum CA125 level in TBPN ($333.7{\pm}283.5\;u/ml$) was higher than in LP ($60.9{\pm}66.2\;u/ml$). (P < 0.05) 2) If we took cut-off value as 195 u/ml in differential diagnosis between TBPN and LP, the sensitivity and specificity of CA125 level in the diagnosis of TBPN were 70% and 93%, respectively. 3) There was no significant difference in serum CA125 level between noncavitary TBPN ($242.1{\pm}76.6\;u/ml$, n=10) and cavitary TBPN ($399.6{\pm}318.4\;u/ml$, n=10). (P > 0.05) 4) Following up of serum CA125 level after initiation of antituberculosis treatment showed rapid decline and approach to near normal range in 6 months. Conclusion : High serum CA125 level (> 195 u/ml) was useful in differential diagnosis of TBPN from LP.

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