• 한국응용과학기술학회지
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• 제35권4호
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• pp.1145-1155
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• 2018

본 연구는 비만여대생을 대상으로 섭식제한(DG), 유산소운동(EG), 섭식제한과 유산소운동(DEG) 그룹으로 나누어 체중, 비만의 개선, 혈중지질성분 및 대사성위험요인에 미치는 영향을 분석하였다. 실험은 8주간 주 5회 실시하였으며, DG는 1일 에너지 섭취열량을 300kcal를 제한하였고, EG는 런닝머신을 이용하여 300kcal를 소비시켰으며, DEG는 각각 150kcal를 제한과 소비시켰다. 결과, 신체조성의 경우 DG에서는 체중(p<.011), BMI(p<.008)가 감소하였고, EG와 DEG에서는 체중(p<.044, p<.017), 체지방량(p<.047, p<.018), BMI(p<.03, p<.008), 체지방률(p<.036, p<.015), WHR(p<.049, p<.027)이 유의하게 감소하였다. 혈중지질성분은 DG에서 HDL-C(p<.028), EG에서 TG(p<.038), DEG에서는 TC(p<.014), LDL-C(p<.007)에서 유의하게 감소하였다. 대사성위험요인은 DG에서 HOMA-IR(p<.035), leptin(p<.007), EG에서 FBG(p<.043), leptin(p<.003), DEG에서 FBG(p<.014), insulin(p<.005), HOMA-IR(p<.005), leptin(p<.016), resistin(p<.040)에서 유의한 차이가 나타났다. 따라서 본 연구의 결과로부터 비만여대생들이 섭식제한, 유산소운동의 단독처치보다 섭식제한과 유산소운동을 병행하는 것이 신체조성, 혈중지질성분, 대사성위험요인의 개선에 가장 효과가 있을 것으로 판단된다.

• 미생물학회지
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• 제52권1호
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• pp.110-115
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• 2016

남극 해양세균 Pseudoalteromonas sp. PAMC 21150에서 분리한 소형 플라스미드(small plasmid, pDK4)의 크기는 3,480bp이고 G+C 함량은 41.64%이며, 3개의 open reading frames(ORFs)을 포함하고 있다. 3개의 ORF는 replication initiation protein (RepA), conjugative mobilization protein (Mob), 그리고 기능이 밝혀지지 않은 단백질을 코팅하고 있다. PCR 반응으로 증폭한 pDK4를 Escherichia coli high-copy pUC19 클로닝 벡터에 삽입하여 fusion vector (pDOC153)를 제작하였고, pDOC 153에 chloramphenicol 저항성 유전자를 삽입하여 ampicillin/chloramphenicol 저항성 Pseudoalteromonas - Escherichia coli 셔틀 벡터(shuttle vector; 7,216 bp 크기; pDOC155)를 제작하였다. 북극 해양세균 P. issachenkonii PAMC 22718이 보유한 2개의 유전자(TonB-dependent receptor gene, chi22718_IV, and exochitinase gene, chi22718_III)를 pDOC155에 삽입하여 두 개의 pDOC155 변형체(pDOC158, pDOC165)를 제작하였다. pDOC158 혹은 pDOC165을 이용하여 triparental mating 방법에 의해 플리스미드 미보유 해양세균인 Pseudoalteromonas sp. PAMC 22137를 형질전환하였다. PCR을 이용한 유전자 증폭실험을 통해서, pDOC158와 pDOC165에 삽입된 유전자들은 Pseudoalteromonas sp. PAMC 22137와 E. coli $DH5{\alpha}$ 내에서 안정적으로 유지되는 것을 확인하였다. 위의 결과는 셔틀 벡터 pDOC155는 Pseudoalteromonas spp. 유래 유전자들을 다른 Pseudoalteromonas spp. 세포 안으로 전달할 수 있는 새로운 유전자 전달시스템으로 이용될 수 있음을 보여주었다.

• 음성과학
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• 제9권4호
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• pp.59-75
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• 2002

Aerodynamic analysis study was performed on 14 normal subjects (2 males, 12 females) with nonsense syllables composed of Korean bilabial stops (/p, p', $p^{h}$) and their preceding and/or following vowels, /i, a, u/. That is, [pi, p'i, $p^{h}i$, pa, p'a, $p^{h}a$, pu, p'u, $p^{h}u$, ipi, apa, upu, $ip^{h}i$, $ap^{h}a$, $up^{h}u$, ip'i, ap'a, up'u]. All measures were taken and analysed using Aerophone II voice function analyzer and included peak air pressure, mean air pressure, maximum flow rate, volume, mean SPL and phonatory SPL. A t-test and one-way ANOVA were employed for analysis. A post-hoc analysis was performed with Scheffe and Bonferroni. The results were as follows: First, MSPL. and MAP of /p, p', $p^{h}$/ were significantly different in different positions (initial and medial position). In addition, different vowel environment also produced significantly different aerodynamic characteristics those consonants. Especially the lax consonant /p/ was significantly different /i, a, u/ vowel environments. The tense consonant /p'/ was significantly different only /i/ vowel environment.

• 정보처리학회논문지C
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• 제13C권4호
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• pp.389-396
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• 2006

P2P(Peer to Peer)는 오늘날 가장 주목 받는 파일 공유 시스템으로 현재 네트워크 트래픽의 50% 가량을 점유하고 있을 정도로 많은 콘텐츠의 유통경로가 되고 있다. 이처럼 P2P는 가장 큰 콘텐츠 유통 경로로 활용되기도 하지만 콘텐츠의 가장 큰 불법 유통 경로로 활용되기도 하며 최근에 들어 음악산업뿐만 아니라 영상산업 전반으로 불법 유통을 야기시키고 있으나 현재 이를 방지하면서 P2P의 장점을 최대한 살릴 수 있는 DRM(Digital Right Management)이 적용된 P2P 모델이 제시되지 못하고 있다. 이에 본 논문에서는 기존 DRM 기능들을 변형하여 기존에 P2P 모델에 적합한 형태로 적용함으로써 기존의 P2P 모델구조를 변형시키지 않고 P2P의 높은 확장성(Scalability)과 분산 처리 성능을 지원할 수 있는 콘텐츠 보호를 위한 DRM이 적용된 P2P 모델을 제안한다.

• 한국동물학회지
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• 제31권2호
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• pp.142-146
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• 1988

PAH화합물의 하나인 benzo(a)pyrene의 쥐 태반 microsomes에 의한 대사활성화를 조사하였다. B(a)P대사물은 C18- $\mu$ Bondapak칼럼을 사용하여 고압액체크로마토그래피로 분석하였다. 그 결과 B(a)P를 투여한 쥐의 태반 microsomes에 의한 주 대사산물은 발암성이 강한 7,8-diol B(a)P였으며, 또한 적은량의 4,5-diol B(a)P와 quinone류가 검출되었다. 3-methyl-cholanthrene을 투여한 경우 hydroxy B(a)P 와 quinone화합물이 주 대사산물이었으며 Phenobarbital을 전처리했을 경우 7,8-diol B(a)P이 주 대사산물인 것으로 나타났다.

• Asian-Australasian Journal of Animal Sciences
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• 제13권6호
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• pp.837-841
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• 2000

The study was conducted at semi urban area in Bangladesh. It was based on a field survey by a prepared questionnaire. Various milking and reproduction performance were analyzed. The effects of grazing hour were found significant on age at weaning (AW) (p<0.001), age at first heat (AFH) (p<0.001), age at first conception (AF conception) (p<0.001), age at first calving (AF calving) (p<0.001), post partum heat period (PPHP) (p<0.001), calving interval (CI) (p<0.001), lactation length (LL) (p<0.001) and total lactational production (TLP) (p<0.001). The effects of concentrate feed were significant on AW (p<0.01), AFH (p<0.01), AF conception (p<0.001), AF calving (p<0.001), PPHP (p<0.001) CI (p<0.001), LL (p<0.001) and TLP (p<0.001). The effects of management level were significant on AW (p<0.001), PPHP (p<0.01), CI (p<0.001), daily milk yield (DMY) (p<0.05) and TLP (p<0.001). The overall mean values were $251.88{\pm}2.97$ days for AW, $37.29{\pm}0.33$ months for AFH, $38.43{\pm}0.34$ months for AF conception, $47.62{\pm}0.34$ months for AF calving, $1.30{\pm}0.02$ number of services per conception (NSPC), $191.57{\pm}3.92$ days for PPHP, $17.02{\pm}0.15$ months for CI, $2.49{\pm}0.06kg$ for DMY, $247.23{\pm}3.51$ days for LL and $590.40{\pm}15.00kg$ for TLP.

• Animal cells and systems
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• 제4권2호
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• pp.181-186
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• 2000

The expression of $p21^{WAF1/ClP1/SDl1}$, one of the cyclin-dependent kinase inhibitors, is regulated by a variety of transcription factors including p53 and STAT. Heat shock induces the expression of p21 in a temperature- and time-dependent manner. Although the p21 induction by heat shock has been reported to be controlled by p53, a p53-independent mechanism Is also involved. To understand the p53-independent regulation of heat shock-induced p21 expression, we searched the promoter region of p21 gene and found one or two heat shock element (HSE)-like sequences in human, rat, and mouse. Electromobility shift assay (EMSA) showed that heat shock factor (HSF) could bind to these HSE-like sequences In response to heat shock, even though to a lesser extent than to HSE. In addition, p21 promoter deletion analysis revealed that heat shock activated a p21 deletion promoter construct containing the HSE-like sequences but lacking p53-binding sites, but not a promoter construct containing neither HSE-like sequences nor the p53-responsive element. Furthermore, the p21 induction by heat shook was significantly inhibited in confluent cells in which heat shock-induced HSF activation was reduced. These results suggest that the transcriptional regulation of p21 by heat shock may be mediated through activation and binding to HSE-like sequences of HSF.

• 동아시아식생활학회지
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• 제17권1호
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• pp.27-42
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• 2007

The purpose of this study is to investigate the importance of well-being related to lifestyle choices such as food habits, food choices, life pattern, etc. The survey was conducted among college students using a questionnaire and a 5-point Likert score in Seoul City and Kyunggido Province during September 2005. The responses of 968 college students were analyzed by the SPSS program. The results were as follows. Most of the subjects were female(76.2%), and lived with their parents (85.6%). The average score of 'food habits', 'choosing food materials', 'purchasing' and 'life pattern' were $2.71{\pm}1.22,\;2.86{\pm}1.28,\;2.41{\pm}1.21,\;and\;2.97{\pm}1.31$ respectively in males and $3.01{\pm}1.20,\;3.00{\pm}1.32,\;2.55{\pm}1.20,and\;2.68{\pm}1.40$ in females, respectively. In regard to 'food habits', the scores were significantly affected by gender(p<0.001), smoking(p<0.05), alcohol consumption(p<0.05), exercise(p<0.001), weight satisfaction(p<0.001), method of weight control(p<0.001), use of nutritional supplement(p<0.05), attempts at weight control(p<0.001), regularity of breakfast(p<0.001), level of interest in well-being(p<0.001), and whether the individual tried a well-being item(p<0.001). In regarding to 'choosing food materials' the scores were significantly affected by gender(p<0.001), smoking(p<0.05), exercise(p<0.001), weight satisfaction(p<0.05), method of weight control(p<0.05), use of nutritional supplement(p<0.05), attempts at weight control(p<0.001), regularity of breakfast(p<0.001), level of interest in well-being(p<0.001) ), and whether the individual tried a well-being item(p<0.001). Out of the factors affecting 'purchasing', the association with BMI was remarkable. Students who were overweight, obese or underweight showed higher average scores than students of normal weight. The primary concerns and trial of well-being of college students were food and exercise. Therefore, the purchase of well-being goods is related to their weight control in college students. In regard to 'life pattern' the scores were significantly affected by exercise(p<0.01), use of computer(p<0.001), BMI(p<0.001), weight control(p<0.001), use of nutritional supplement(p<0.05), regularity of breakfast(p<0.001), level of interest in wellbeing(p<0.001), whether the individual tried a well-being item(p<0.001), and having taken lecture on well-being(p<0.05). Therefore nutrition education is needed for healthy eating habits of college students and it is necessary to develop a series of lectures to teach them about diet and exercise programs.

• Journal of Preventive Medicine and Public Health
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• 제45권3호
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• pp.137-147
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• 2012

We conducted a systematic review to summarize providers' attitudes toward pay-for-performance (P4P), focusing on their general attitudes, the effects of P4P, their favorable design and implementation methods, and concerns. An electronic search was performed in PubMed and Scopus using selected keywords including P4P. Two reviewers screened target articles using titles and abstract review and then read the full version of the screened articles for the final selections. In addition, one reference of screened articles and one unpublished report were also included. Therefore, 14 articles were included in this study. Healthcare providers' attitudes on P4P were summarized in two ways. First, we gathered their general attitudes and opinions regarding the effects of P4P. Second, we rearranged their opinions regarding desirable P4P design and implementation methods, as well as their concerns. This study showed the possibility that some healthcare providers still have a low level of awareness about P4P and might prefer voluntary participation in P4P. In addition, they felt that adequate quality indicators and additional support for implementation of P4P would be needed. Most healthcare providers also had serious concerns that P4P would induce unintended consequences. In order to conduct successful implementation of P4P, purchaser should make more efforts such as increasing providers' level of awareness about P4P, providing technical and educational support, reducing their burden, developing a cooperative relationship with providers, developing more accurate quality measures, and minimizing the unintended consequences.

• 식물분류학회지
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• 제35권1호
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• pp.25-46
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• 2005

한국산 Platanthera(제비난초속)를 외부형태학적 특징, 특히 꽃의 구조를 바탕으로 검토하였다. Platanthera와 순판 기부 양쪽의 돌출 부분 유무로 구분하던 Tulotis는 그 형질이 뚜렷하지 않아 Platanthera로 통합하는 견해를 지지하였다. 분류학적 처리에서, 현재까지 우리나라 대부분의 문헌에서 P. metabifolia라고 기재한 제비난초는 P. chlorantha의 오동정임이 확인되었으며, 아울러 P. neglecta(하늘산제비란)는 P. mandarinorum(산제비란)과 별개의 종으로 처리하는 것이 타당한 것으로 나타났다. 한국산 제비난초속 식물을 P. chlorantha(제비난초), P. mandarinorum(산제비란), P. neglecta(하늘산제비란), P. hologlottis(흰제비란), P. japonica(갈매기난초), P. ophrydioides(구름제비란), P. ussuriensis(제비잠자리란), P. fuscescens(나도잠자리란)의 8종으로 정리하였으며, 동시에 한국산 제비난초속의 검색표를 작성하였고 이들의 분류학적 문제점을 논의하였다.