• Korean Journal of Microbiology
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• v.36 no.3
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• pp.221-227
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• 2000

This study was performed to investigate the biological characteristics of twenty isolates of extended spectnlm $\beta$-lactamase (ESBL) producing Klebsiellapnezm~onia collected kom the various clinical specimens of three hospitals in Pusan. Isoelectric focusing (IEF) and PCR were used to determine the types of $\beta$-lactamase gene in this study. Twenty isolates of ESBL producing Klebsiellnp~ieun~or~iae could be divided by PCR, such as TEM type (I1 strains), SHV type (8 strains); non TEM non SHV type (1 strain). In the isoelechic focusing test, the PI of TEM type was 5.2-6.0 and that of SHV type was 6.9-7.4. According to the pI value and PCR bands, twenty strains of ESBL Klebsiellapneumoniae were divided into 5 types: TEM type @I 5.2-6.0; 1080 bp on PCR band), TEM + SHV type (pI 5.2-6.0; andpI 7.0-7.4; 1080 bp and 599 bp on PCR band), SHV type (pl7.0-7.4; 599 bp on PCR band), non TEM non SHV type, and otber type (PCR result was SHV type but pI was not detected).

• Journal of Mechanical Science and Technology
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• v.16 no.4
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• pp.476-484
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• 2002

The aim of this study is to investigate the ductile fracture behavior under mixed mode (I/II) loading using SA533B pressure vessel steel. Anti-symmetric 4-point (AS4P) bending tests were performed to obtain the J-R curves under two different mixed mode (I/II) loadings. In addition, finite element analysis using Rousselier Ductile Damage Theory was carried out to predict the J-R curves under mixed mode (I/II) loadings. In conclusions, the J-R curves under. Mixed Mode (I/II) loading were located between those of Mode I and Mode II loading. When the mixity of mixed mode (I/II) loading was high, the J-R curve of mixed mode (I/II) loading approached that of pure mode I loading after some amount of crack propagation. In contrast with the above fact, if the mixity was low, the J-R curve took after that of pure mode II loading. Finally, it was found that the predicted J-R curves made a good agreement with the test data through the tuning procedures of $\beta$ values at the different mixed mode (I/II) loading.

• Journal of Digital Convergence
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• v.14 no.11
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• pp.333-345
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• 2016

This study was to determine the relationship between nurse DISC personality types, self-efficacy, clinical performance. Data were collected from 302 nurses in 5 hospitals in K city. Data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient. With regard to self-efficacy and clinical performance, D type showed a higher score than type I type and S type. The lower region of the clinical performance showed the nursing process, nursing skills, higher score than the D Type S Type in professional development. With regard to personality and self-efficacy, and clinical performance, the type D (r=.56, p<.01), I type (r=.66, p<.01), S type (r=.6, p<.01) showed a positive correlation with type C (r=.52, p<.01). As shown by these results, each personality type has a different correlation with self-efficacy and clinical performance ability. This factor should be considered in the assignment of nurses to departments or individual training programs so that they can deliver the most effective job performance.

• Food Science of Animal Resources
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• v.40 no.2
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• pp.183-196
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• 2020

The protective effect of pig skin gelatin water extracts (PSW) and the low molecular weight hydrolysates of PSW generated via enzymatic hydrolysis with Flavourzyme® 1000L (LPSW) against scopolamine-induced impairment of cognitive function in mice was determined. Seventy male ICR mice weighing 20-25 g were randomly assigned to seven groups: Control (CON); scopolamine (SCO, 1 mg/kg B.W., intraperitoneally (i.p.); tetrahydroaminoacridine 10 [THA 10, tacrine; 10 mg/kg B.W. per oral (p.o.) with SCO (i.p.)]; PSW 10 (10 mg/kg B.W. (p.o.) with SCO (i.p.); PSW 40 (40 mg/kg B.W. (p.o.) with SCO (i.p.); LPSW 100 (100 mg/kg B.W. (p.o.) with SCO (i.p.); LPSW 400 (400 mg/kg B.W. (p.o.) with SCO (i.p.). All treatment groups, except CON, received scopolamine on the day of the experiment. The oxygen radical absorbance capacity of LPSW 400 at 1 mg/mL was 154.14 μM Trolox equivalent. Administration of PSW and LPSW for 15 weeks did not significantly affect on physical performance of mice. LPSW 400 significantly increased spontaneous alternation, reaching the level observed for THA and CON. The latency time of animals receiving LPSW 400 was higher than that of mice treated with SCO alone in the passive avoidance test, whereas it was shorter in the water maze test. LPSW 400 increased acetylcholine (ACh) content and decreased ACh esterase activity (p<0.05). LPSW 100 and LPSW 400 reduced monoamine oxidase-B activity. These results indicated that LPSW at 400 mg/kg B.W. is a potentially strong antioxidant and contains novel components for the functional food industry.

• Journal of the Korean Chemical Society
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• v.54 no.1
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• pp.77-87
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• 2010

Hospital-acquired methicillin-resistant Staphylococcus aureus (MRSA) has been an increasing problem worldwide since the initial reports over 40 years ago. To examine new drug leads with potential antibacterial activities, Various N'-[(-3-substituted-4-oxo-1,3-thiazolidin-2-ylidene]-4-hydroxy benzohydrazide (4a-4.i) and N'-[-(3,4-disubstituted)-1,3-thiazolidin-2ylidene)]-4-hydroxybenzohydrazide from (5.a-5.i) to (10.a-10.i) were synthesized using appropriate synthetic route. The entire test compounds (4.a-4.i) and from (5.a-5.i) to (10.a-10.i) were assayed in vitro against s. aureus strain. The minimum inhibitory concentration (MIC) was determined for test compounds and for reference standards. The test compounds showed significant antibacterial activity against the strains used, when tested in vitro. In general, p-hydroxybenzohydrazide ring and substituted thiazoline ring are essential for antimicrobial activity. Among the compounds tested, compounds 6.f, 7.g, 9.f and 10.f, 10 i were found to be most potent. The test compounds were found nontoxic upto the dose level of 2000 ${\mu}g$/mL. The intact compounds were then subjected for 3D-QSAR studies. 3D-QSAR study based on the principal of alignment of pharmacophoric features by Schrodinger PHASE module. The 3D-QSAR study allowed us to confirm the preferential binding mode of p-hydroxybenzohydrazide inside the active site.

• Journal of the Korean Society of Physical Medicine
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• v.16 no.2
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• pp.63-70
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• 2021

PURPOSE: This study aimed to analyze the factors influencing the improvement of global synkinesis (GS) and gait in stroke patients by the weight shift exercise. METHODS: Twenty stroke patients were randomly assigned to experimental group I (n = 10) and experimental group II (n = 10). In experimental group I, weight shift with upper extremity exercises in a standing position were mediated and in experimental group II, upper extremity exercises in a standing position were mediated. These interventions were conducted in both groups for three sessions per week, 30 minutes per session over four weeks. Before the interventions, leg GS was measured using surface electromyography and the 10m walk test (10MWT). The same parameters were measured four weeks later. RESULTS: The GS and 10MWT of the experimental group I showed that there was a statistically significant difference between dorsiflexion (p < .05) and plantarflexion (p < .01) and 10MWT (p < .01). In experimental group II, there was a statistically significant difference only in 10MWT (p < .01). The comparison between the changes in both groups showed that in the case of GS, there was a statistically significant difference in the dorsiflexion (p < .01) and plantarflexion (p < .05), and in the 10MWT too (p < .05). CONCLUSION: GS of the lower extremities was decreased by improving posture control and enlarging soft tissues due to the symmetrical weight shift in experimental group I, which turned out to be effective in improving the gait speed.

• Speech Sciences
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• v.9 no.4
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• pp.59-75
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• 2002

Aerodynamic analysis study was performed on 14 normal subjects (2 males, 12 females) with nonsense syllables composed of Korean bilabial stops (/p, p', $p^{h}$) and their preceding and/or following vowels, /i, a, u/. That is, [pi, p'i, $p^{h}i$, pa, p'a, $p^{h}a$, pu, p'u, $p^{h}u$, ipi, apa, upu, $ip^{h}i$, $ap^{h}a$, $up^{h}u$, ip'i, ap'a, up'u]. All measures were taken and analysed using Aerophone II voice function analyzer and included peak air pressure, mean air pressure, maximum flow rate, volume, mean SPL and phonatory SPL. A t-test and one-way ANOVA were employed for analysis. A post-hoc analysis was performed with Scheffe and Bonferroni. The results were as follows: First, MSPL. and MAP of /p, p', $p^{h}$/ were significantly different in different positions (initial and medial position). In addition, different vowel environment also produced significantly different aerodynamic characteristics those consonants. Especially the lax consonant /p/ was significantly different /i, a, u/ vowel environments. The tense consonant /p'/ was significantly different only /i/ vowel environment.

• Journal of Sasang Constitutional Medicine
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• v.16 no.1
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• pp.112-119
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• 2004

Objectives This paper was designed for studying the features of digestion according to Sasang Constitution and to be helpful to make a diagnosis Sasang Constitution. Using the result of this study, it will be helpful to diagnose a Sasang constitution. Methods There were 588 patients(248 men, 340 women) who answered questionnaire and were diagnosed by the Sasang Constitution Specialist at Constitutional Clinic of Dongguk Bundang Oriental Hospital. Using the response of questionnaire and several statistical techniques such as homogeneity test and multiple comparison, we tried to find the characteristics of each constitution depending on its dining behavior. Results As a result of the analysis of questionnaire, Taeumin and Soyangin answered to 'Because digestion is well, I overeat frequently' many more than Soeumin(p<0.01). Soeumin answered to 'When I eat cold food or greasy food, it hardly digests' many more than Taeumin(p<0.05). Soeumin and Taeyangin answered to 'Because I have indigestion, I have suffered from infancy' many more than Taeumin(p<0.01). Soeumin answered to 'I have easily a digestive upset' many more than Taeumin(p<0.01). Soeumin answered to 'indigestion in case of paying attention' many more than Taeumin and Soyangin(p<0.01).

• The Journal of Advanced Prosthodontics
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• v.13 no.5
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• pp.316-326
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• 2021

PURPOSE. Purpose of this in vitro study was to determine the accuracy of different intraoral scans versus laboratory scans of impressions and casts for the digitization of an edentulous maxilla. MATERIALS AND METHODS. A PEEK model of an edentulous maxilla, featuring four hemispheres on the alveolar ridges in region 13, 17, 23 and 27, was industrially digitized to obtain a reference dataset (REF). Intraoral scans using Cerec Primescan AC (PRI) and Cerec AC Omnicam (OMN), as well as conventional impressions (scannable polyvinyl siloxane) were carried out (n = 25). Conventional impressions (E5I) and referring plaster casts were scanned with the inEOS X5 (E5M). All datasets were exported in STL and analyzed (Geomagic Qualify). Linear and angular differences were evaluated by virtually constructed measurement points in the centers of the hemispheres (P13, P17, P23, P27) and lines between the points (P17-P13, P17-P23, P17-P27). Kolmogorov-Smirnov test and Shapiro-Wilk test were performed to test for normal distribution, Kruskal-Wallis-H test, and Mann-Whitney-U test to detect significant differences in trueness, followed by 2-sample Kolmogorov-Smirnov test to detect significant differences in precision (P < .008). RESULTS. Group PRI showed the highest trueness in linear and angular parameters (P < .001), while group E5I showed the highest precision (P < .001). CONCLUSION. Intraoral scan data obtained using Primescan showed the highest trueness while the indirect digitization of impressions showed the highest precision. To enhance the workflow, indirect digitization of the impression itself appears to be a reasonable technique, as it combines fast access to the digital workflow with the possibility of functional impression of mucosal areas.

• IT SoC Magazine
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• s.19
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• pp.37-42
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• 2007

이 글은 당사에서 개발 진행한 TDMB,ISDB-T등의 Moblie TV Receiver단의 Analog Front-End SIP들의 Test H/W, S/W제작 경험을 바탕으로 보다 효율적이고 성공적인 SIP 개발이 될 수 있도록 도움을 주고자 기술 하였다.