• 한국원자력학회:학술대회논문집
• /
• 한국원자력학회 1996년도 추계학술발표회논문집(2)
• /
• pp.521-526
• /
• 1996

원자력 발전소 내의 1차계통수에 존재하는 부식생성물과 노심에서 방사화된 여러 핵종들의 종류와 그 양에 대해서 CRUDSIM/MIT모형을 이용해서 분석하였다. 고리 4호기의 차계통수내의 수화학 조건을 이용하여 CRUDSIM/MIT모형에 적용하고 그 결과를 냉각수의 Activity자료와 증기 발생기의 Activity자료와 서로 비교 분석하였고, 노심과 증기발생기의 Crud양과 Activity를 예상하였다. 이 모형의 주요 인자인 $\beta$$_{c}$와 $\beta$$_{a}$ 값을 증기발생기의 Activity측정자료에 의해서 구하였다. 그리고 발전소 운전 중에 증기 발생기와 냉각수의 Activity각 최소화 할 수 있는 최적 조건 범위도 냉각수의 온도, pH, 수소농도등을 변화시켜서 구하였다. 고리4호기에 이 모형을 적용할 때 입력 자료에서, Activation Factor와 Recoil Release 등의 인자와 증기 발생기의 방사선양과 핵연료 표면의 Crud양을 구할 수 있으면 더욱 정확한 결과 값들을 얻을 수 있다.

• Korean Journal of Mathematics
• /
• 제29권3호
• /
• pp.519-526
• /
• 2021

In a very recent paper, Yousef et al. [Anal. Math. Phys. 11: 58 (2021)] introduced two new subclasses of analytic and bi-univalent functions and obtained the estimates on the first two Taylor-Maclaurin coefficients |a₂| and |a₃| for functions belonging to these classes. In this study, we introduce a general subclass 𝔅^h,p_Σ(λ, μ, 𝛿) of analytic and bi-univalent functions in the unit disk 𝕌, and investigate the coefficient bounds for functions belonging to this general function class. Our results improve the results of the above mentioned paper of Yousef et al.

• 한국초지조사료학회지
• /
• 제22권2호
• /
• pp.131-136
• /
• 2002

본 시험은 가축분 시용 조건에서 $수수{\times}수단그라스$ 교잡종중 우리나라에서 많이 재배하고 있는 장려품종 4종(P 988, Jumbo, TE-Hay-grazer, NC+ 855)을 공시하여 생육시기별, 잎과 줄기의 부위별 질산태 질소 함량과 당도 및 가축 기호도 등을 구명하였다. 가축분은 톱밥과 50:50으로 섞은 발효분으로 ha당 우분 40톤, 돈분 및 계분은 30톤을 파종 보름전 시용하였으며, 파종은 ha당 30kg의 종자를 휴폭 50cm로 1995년 4월 21일에 실시하였다. 수수${\times}$수단그라스 교잡종의 질산태 질소 함량은 초장 50~50cm일 때 365mg/kg, 초장 100~120cm일 때 501mg, 초장 200~220cm일 때 502mg이었으며, 품종별로는 Jumbo에서 평균 317mg으로 낮았고 P 988(526mg)과 NC+ 855 (519mg)에서 높았다(P<0.05). 또 품종에 관계없이 줄기(376mg)가 잎(135mg)에 비해 질산태 질소함량이 크게 높았으며(P<0.05), 같은 잎과 줄기에서는 아래부위로 갈수록 질산태 질소 함량은 유의적으로 증가하였다(P<0.05). 품종별 당도는 NC+ 855가 평균 $3.9^{\circ}$ 로 가장 높았으며, 다음이 P 988($3.4^{\circ}$), TE-Hay grazer ($3.2^{\circ}$), Jumbo($2.9^{\circ}$) 순이었다. 채식률은 P 988과 NC+ 855에서 Jumbo와 TE-Haygrazer에 비해 다소 높은 경향이었으나 장려품종 4종간 유의적인 채식률 차이는 없었다.

• 한국치위생학회지
• /
• 제20권1호
• /
• pp.41-51
• /
• 2020

Objectives: The purpose of this study was to investigate the effects of oral health behaviors of patients with hypertension and diabetic patients on the number of remaining teeth in Korean adults over 45 years of age, furthermore, we also aimed to develop oral health care programs and health promotion for patients with hypertension and diabetes. Methods: Altogether, 1,526 subjects with hypertension and diabetes from the 6th Korean National Health and Nutrition Survey (2013-2015) were analyzed. Results: A multiple logistic regression analysis was performed to determine the effects of oral health behavior and periodontal disease on residual teeth in patients with hypertension and diabetes after adjusting for age. We found 1.53 times the risk of having less than 20 remaining teeth in the group of brushing more than 3 times a day (95% CI: 1.00,2.35, p<0.001), 2.27 times (95% CI: 1.23-4.17, p<0.05) in the group not using the dental floss group 0.05), compared to the group undergoing regular dental check-up (95% CI: 0.93-1.85, p>0.05), compared to the non-smoking group 0.77 times (95% CI: 0.51-1.14, p>0.05), 1.33 times (95% CI: 0.98-1.80, p>0.05) in the drinking group compared to the non-drinking group, in the periodontal disease group, the risk of having less than 20 remaining teeth was 2.19 times higher (95% CI: 1.48-3.24, p>0.001) than in the normal group. Conclusions: As a super-aging society, develops in Korea, the prevalence of hypertension and diabetes will increase gradually. Therefore, an oral health policy should be implemented at the national level for the prevention and treatment of periodontal disease as well as the management of oral health the elderly.

• Journal of Microbiology
• /
• 제44권1호
• /
• pp.35-41
• /
• 2006

The unique gene encoding thioredoxin reductase (TrxR) was previously cloned and characterized from the fission yeast Schizosaccharomyces pombe, and its expression was induced by oxidative stress. To elucidate tbe regulatory mechanism of the S. pombe TrxR gene, three fusion plasmids were generated using polymerase chain reaction: pYUTR20, pYUTR30, and pYUTR40. Plasmid pYUTR20 has an upstream region of 891 base pairs, pYUTR30 has 499 in this region, and pYUTR40 has an 186 bp upstream region. Negatively acting sequence is located between $-1,526\;\~\;-891bp$ upstream of the gene. The upstream sequence, responsible for the induction of TrxR by menadione (MD), is situated on the $-499\;\~\;-186bp$ region, which is also required for TrxR induction by mercuric chloride. The same region also appeared to be required for Pap1-mediated transcriptional regulation of the TrxR gene, which contains the two plausible Papl binding sites, TTACGAAT and TTACGCGA. Consistently, basal and inducible expression of the TrxR gene was markedly lower in the Pap1-negative TP108-3C cells than in wild-type yeast cells. In summary, up-regulation of the S. pombe TrxR gene is mediated by Pap1 via the transcriptional motif(s) located on the $-499\;\~\;-186bp$ region.

• Nutrition Research and Practice
• /
• 제5권6호
• /
• pp.520-526
• /
• 2011

Folate deficiency and hyperhomocysteinemia are found in most patients with alcoholic liver disease. Oxidative stress is one of the most important mechanisms contributing to homocysteine (Hcy)-induced tissue injury. However it has not been examined whether exogenous administration of folic acid attenuates oxidative stress and hepatic toxicity. The aim of this study was to investigate the in vivo effect of folic acid supplementation on oxidative stress and hepatic toxicity induced by chronic ethanol consumption. Wistar rats (n = 32) were divided into four groups and fed 0%, 12%, 36% ethanol, or 36% ethanol plus folic acid (10 mg folic acid/L) diets. After 5 weeks, chronic consumption of the 36% ethanol diet significantly increased plasma alanine transaminase (ALT) (P < 0.05) and aspartate transaminase (AST) (P < 0.05), triglycerides (TG) (P < 0.05), Hcy (P < 0.001), and low density lipoprotein conjugated dienes (CD) (P < 0.05) but decreased total radical-trapping antioxidant potential (TRAP) (P < 0.001). These changes were prevented partially by folic acid supplementation. The 12% ethanol diet had no apparent effect on most parameters. Plasma Hcy concentration was well correlated with plasma ALT (r = $0.612^{**}$), AST (r = $0.652^*$), CD (r = $0.495^*$), and TRAP (r = $-0.486^*$). The results indicate that moderately elevated Hcy is associated with increased oxidative stress and liver injury in alcohol-fed rats, and suggests that folic acid supplementation appears to attenuate hepatic toxicity induced by chronic ethanol consumption possibly by decreasing oxidative stress.

• Journal of Chest Surgery
• /
• 제33권6호
• /
• pp.507-511
• /
• 2000

Background: The prognosis for young patients generally considered to be poor. The purpose of this study was to determined whether the clinical characteristics and the survival rate in young lung cancer patients after surgical treatment differs from that in older patients. Material and Method: Of 526 patients, 28(5.3%) were 30 to 40 years old. We studied the clinical characteristics and prognosis of 28 patients aged 40 years or less(Group 1), in whom primary lung cancer was diagnosed and operated between 1990 and 1997, and compared them with those 498 patients aged more than 40 years(Group 2). Result: The differences in sex ratio that were higher for women in Group 1, but there was no significant difference (p=0.297). The percentages for smokers and symptoms in Group 1 were significantly less than in Group 2.(p=0.049, p=0.008). Adenocarcinoma was significantly more common (p=0.018) and squamous cell diagnosed was diagnosed as stage IIIb or stage IV in 9 patients(32.1%), while 12.0% of the patients older than 40 years of age had either stage IIIb or stage IV(p=0.002). The 5-year survival rate was 41.3% in Group 1 ; 37.7% in Group 2, and the median survival time was 24.3 months in Group 1 ; 27.0 months is Group 2. There were no significant difference in survival between two age groups(p=0.808). Conclusion: Younger patients have more adenocarcinoma, however have less squamous cell carcinoma, less symptoms and less smoking history. Although younger patients tended to have more advanced disease and less complete resection rate, the recurrence and the long term survival in these patients did not differ that of older patients.

• 한국미생물·생명공학회지
• /
• 제16권6호
• /
• pp.526-531
• /
• 1988

방선균의 단백질 분해효소를 황산 암모늄분획, Sephadex G-75-50 gel filtration, DEAE-Sephadex A-50 ion-exchange chromatography, ultrafiltration 등의 과정을 통해 정제하였다. 염기성 단백질 분해 효소의 분자량은 SDS 전기영동에 의해 23,500 dalton 이었으며 Hammarsten casein에 대한 Km값은 0.8g/l였고 이때 Vmax값은 15.1 $\mu$mole/min/mg 이었다. 효소반응 최적 pH는 9.0이었고 최적 반응온도는 5$0^{\circ}C$였다. pH에 대한 안정성은 9.0-10.0 에서 최대로 안정하였고 5$0^{\circ}C$ 이상에서는 효소가 불활성화되었다. 중성단백질 분해효소의 분자량은 38900 dalton 이었으며 Hammarsten casein에 대한 Km값은 0.54g/l였고 이때 Vmax값은 12.4 $\mu$mole/min/mg이었다. 효소반응 최적 pH는 7.0이었고 최적 반응온도는 35$^{\circ}C$였다. pH 7.0-9.0에서는 안정하였으나 4$0^{\circ}C$ 이상에서는 신속하게 불활성화되었다.

• Korean Journal of Radiology
• /
• 제21권5호
• /
• pp.526-536
• /
• 2020

Objective: This study aimed to evaluate the clinical benefits and risks of CT-guided percutaneous transthoracic needle lung biopsies (PTNBs) in patients with a suspected pulmonary infection. Materials and Methods: This study included 351 CT-guided PTNBs performed in 342 patients (mean age, 58.9 years [range, 17-91 years]) with suspected pulmonary infection from January 2010 to December 2016. The proportion of biopsies that revealed the causative organism for pulmonary infection and that influenced patient's treatment were measured. Multivariate analyses were performed to identify factors associated with PTNB that revealed the causative organism or affected the treatment. Finally, the complication rate was measured. Results: CT-guided PTNB revealed the causative organism in 32.5% of biopsies (114/351). The presence of necrotic components in the lesion (odds ratio [OR], 1.7; 95% confidence interval [CI], 1.1-2.7; p = 0.028), suspected pulmonary tuberculosis (OR, 2.0; 95% CI, 1.2-3.5; p = 0.010), and fine needle aspiration (OR, 2.5; 95% CI, 1.1-5.8; p = 0.037) were factors associated with biopsies that revealed the causative organism. PTNB influenced patient's treatment in 40.7% (143/351) of biopsies. The absence of leukocytosis (OR, 1.9; 95% CI, 1.0-3.7; p = 0.049), presence of a necrotic component in the lesion (OR, 2.4; 95% CI, 1.5-3.8; p < 0.001), and suspected tuberculosis (OR, 1.7; 95% CI, 1.0-2.8; p = 0.040) were factors associated with biopsies that influenced the treatment. The overall complication rate of PTNB was 19% (65/351). Conclusion: In patients with suspected pulmonary infection, approximately 30-40% of CT-guided PTNBs revealed the causative organism or affected the treatment. The complication rate of PTNB for suspected pulmonary infection was relatively low.

• 동아시아식생활학회지
• /
• 제7권4호
• /
• pp.519-526
• /
• 1997

Propylene oxide와 반응시켜 치환도가 0-0.2645되는 하이드록시프로필화 감자 전분을 제조하여 이화학적 성질들을 측정하였다. 전분의 하이드록시프로필기 함량은 propylene oxide의 농도에 비례하였다. 하이드록시프로필화 감자 전분의 물결합력은 치환도가 증가할수록 증가하였고 pH는 치환도가 증가할수록 감소하였다. 청가와 요오드 흡착 강도는 치환도가 증가할수록 감소하였다. 시차주사열량계에 의한 호화양상에서는 하이드록시프로필화에 의해 전분의 호화온도가 낮아지는 것으로 나타났다. 하이드록시프로필화에 의해 전분의 상대 결정 화도는 낮아졌고, 전분 입자가 파괴되었음이 X-선 회절도와 주사전자현미경으로 각각 관찰되었다. 이것은 고농도의 하이드록시프로필화가 전분의 무정형 부분뿐만 아니라 결정성 영역에까지 영향을 주었음을 의미하였다.