• 제목/요약/키워드: P-y analysis

검색결과 27,678건 처리시간 0.047초

No Association Between MTHFR A1298C Gene Polymorphism and Head and Neck Cancer Risk: A Meta-analysis Based on 9,952 Subjects

  • Niu, Yu-Ming;Shen, Ming;Li, Hui;Ni, Xiao-Bing;Zhou, Juan;Zeng, Xian-Tao;Leng, Wei-Dong;Wu, Ming-Yue
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권8호
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    • pp.3943-3947
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    • 2012
  • Objective: Findings for associations between the methylenetetrahydrofolate reductase (MTHFR) A1298C gene polymorphism and head and neck cancer risk have been conflicting. We therefore performed a meta-analysis to derive a more precise relationship. Methods: Ten published case-control studies were collected and odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the association between MTHFR A1298C polymorphism and head and neck cancer risk. Sensitivity analysis and publication bias assessment also were performed to guarantee the statistical power. Results: Overall, no significant association between MTHFR A1298C polymorphism and head and neck cancer risk was found in this meta-analysis (C vs. A: OR=1.04, 95%CI=0.87-1.25, P=0.668, Pheterogeneity<0.001; CC vs. AA: OR=1.07, 95%CI=0.70-1.65, P=0.748, $P_{heterogeneity}<0.001$; AC vs. AA: OR=1.06, 95%CI=0.88-1.27, P=0.565, $P_{heterogeneity}<0.001$; CC+AC vs. AA: OR=1.06, 95%CI=0.86-1.30, P=0.571, $P_{heterogeneity}<0.001$; CC vs. AA+AC: OR=1.02, 95%CI=0.69-1.52, P=0.910, $P_{heterogeneity}<0.001$). Similar results were also been found in succeeding analysis of HWE and stratified analysis of ethnicity. Conclusion: In conclusion, our meta-analysis demonstrates that MTHFR A1298C polymorphism may not be a risk factor for developing head and neck cancer.

CPT-based p-y analysis for mono-piles in sands under static and cyclic loading conditions

  • Kim, Garam;Kyung, Doohyun;Park, Donggyu;Lee, Junhwan
    • Geomechanics and Engineering
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    • 제9권3호
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    • pp.313-328
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    • 2015
  • In the present study, a CPT-based p-y analysis method was proposed for offshore mono-piles embedded in sands. Static and cyclic loading conditions were both taken into account for the proposed method. The continuous soil profiling capability of CPT was an important consideration for the proposed method, where detailed soil profile condition with depth can be readily incorporated into the analysis. The hyperbolic function was adopted to describe the non-linear p-y curves. For the proposed hyperbolic p-y relationship, the ultimate lateral soil resistance $p_u$ was given as a function of the cone resistance, which is directly introduced into the analysis as an input data. For cyclic loading condition, two different cyclic modification factors were considered and compared. Case examples were selected to check the validity of the proposed CPT-based method. Calculated lateral displacements and bending moments from the proposed method were in good agreement with measured results for lateral displacement and bending moment profiles. It was observed the accuracy of calculated results for the conventional approach was largely dependent on the selection of friction angle that is to be adopted into the analysis.

인솔 차이에 따른 런닝화의 운동역학적 비교 (The Biomechanical Comparison of Running Shoes According to the Difference of Insole)

  • 진영완;신성훈
    • 한국운동역학회지
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    • 제17권2호
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    • pp.51-59
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    • 2007
  • These studies show that I applied to functional insole (a specific A company) for minimizing shocks and sprain people's ankle arising from running. How to an effect on human body which studied a kinematics and kinetics from 10 college students during experiments. This study imposes several conditions by barefoot, normal running shoes and put functional insole shoes ran under average $2.0{\pm}0.24\;m$/sec by motion analysis and ground reaction force that used to specific A company. First of all, motion analysis was caused by achilles tendon angle, angle of the lower leg, angle of the knee, initial sole angle and barefoot angle. The result of comparative analysis can be summarized as below. Motion analysis showed that statically approximates other results from achilles tendon angle (p<.01), initial ankle angle(p<.05), initial sole angle(p<.001) and barefoot angle(p<.001). Ground reaction force also showed that statically approximates other results from impact peak timing (p<.001), Maximum loading rate(p<.001), Maximum loading rate timing (p<.001) and impulse of first 20 percent (p<.001). Above experiment values known that there was statically difference between Motion analysis and Ground reaction force under absorbing of the functional insole shoes which was not have an effect on our body for kinetics and kinematics.

Prediction of product parameters of fly ash cement bricks using two dimensional orthogonal polynomials in the regression analysis

  • Chakraverty, S.;Saini, Himani;Panigrahi, S.K.
    • Computers and Concrete
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    • 제5권5호
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    • pp.449-459
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    • 2008
  • This paper focuses on the application of two dimensional orthogonal polynomials in the regression analysis for the relationship of product parameters viz. compressive strength, bulk density and water absorption of fly ash cement bricks with other process parameters such as percentages of fly ash, sand and cement. The method has been validated by linear and non-linear two parameter regression models. The use of two dimensional orthogonal system makes the analysis computationally efficient, simple and straight forward. Corresponding co-efficient of determination and F-test are also reported to show the efficacy and reliability of the relationships. By applying the evolved relationships, the product parameters of fly ash cement bricks may be approximated for the use in construction sectors.

불교란 점토 압밀시험 결과의 새로운 해석법 (A New Analysis Method of the Consolidation Test Data for an Undisturbed Clay)

  • 박종화;고우모또타쯔야
    • 한국농공학회지
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    • 제44권6호
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    • pp.106-114
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    • 2002
  • In this study, the results of a series of consolidation test for undisturbed Ariake clay in Japan were analyzed by three methods, e-log p (e: void ratio, p: consolidation pressure), log e-log p and n-log p (n: porosity). Moreover, the characteristics of each analysis method were studied. For undisturbed Ariake clay, the log o-Log p and the n-log p relationships can be found as two groups of straight lines of different gradients, but both the elastic consolidation and plastic consolidation regions of e-log p relationship are expressed as a curve. In this paper, the porosity of consolidation yield n$\_$y/, consolidation yield stress p$\_$y/, and the gradient of the plastic consolidation region C$\_$p/ were represented by the log e-log p method, and n$\_$c/, P$\_$cn/ and C$\_$cn/ were represented by the n-log p method. The meaning and the relationships of each value were studied, and the interrelationships among compression indices i.e. C$\_$cn/, C$\_$p/ and C$\_$c/ are obtained from each analysis method as a function of initial porosity n$\_$0/.

SNS를 통한 외식선택속성이, 고객만족도, 타인추천 영향관계 (Through SNS Eat Out Select Properties, Customer Satisfaction, Recommendation of Others Affect Relations)

  • 김건휘;한지수
    • 한국조리학회지
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    • 제22권4호
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    • pp.143-155
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    • 2016
  • 본 연구에서는 SNS를 통한 외식선택속성이 고객만족도와 타인추천에 어떤 영향을 미치는지를 파악하기 위하여 SNS를 통해 외식업체를 방문한 경험이 있는 소비자들을 대상으로 설문조사를 시행하여 실증분석을 하였다. 총 350부의 설문지를 배포하여 불성실하게 응답한 28부의 설문지를 제외한 나머지 322부의 유효한 설문지를 실증연구에 사용되었다. 조사 연구의 목적을 달성하기 위하여 통계프로그램 SPSS 22.0을 활용하여 빈도분석, 요인분석 및 신뢰도분석, 상관관계분석, 회귀분석을 실시하였다. 분석결과를 보면 첫째, 외식선택속성은 고객만족에 미치는 영향에 관한 다중회귀분석 결과는 전체 회귀식의 설명력은 $R^2=.521$(adjusted $R^2=.515$)이고, F값은 86.325이고, 회귀식은 p=0.000으로 정(+)의 영향력으로 통계적으로 유의한 것으로 분석되었다. 독립변수 중 실속 추구형(B=0.540, p<0.001), 안전 추구형(B=0.292, p<0.001)은 유의하게 나타나 정(+)의 영향력이 나타났고, 편의 추구형(B=0.071, p<0.001)과 품위 추구형(B=0.002, p<0.001)은 부(-)의 영향력이 나타났다. 둘째, 고객만족도가 타인추천에 미치는 영향에 관한 다중회귀분석 결과는 전체 회귀식의 설명력은 $R^2=.539$(adjusted $R^2=.538$)이고, F값은 374.765이고, 회귀식은 p=0.000으로 통계적으로 유의한 것으로 분석되어 회귀선모델이 적합하다는 것으로 나타났다. 독립변수 고객만족도(B=0.540, p<0.001)는 정(+)의 영향력이 나타났다.

P2P Network Simulation System for Performance Evaluation in Convergence Networks

  • Kim, Yu-Doo;Moon, Il-Young
    • Journal of information and communication convergence engineering
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    • 제9권4호
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    • pp.396-400
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    • 2011
  • P2P(peer to Peer) network is a distributed network architecture composed of participants that make a portion of their resources directly available to other network participants, without the need for a central server. Currently, convergence network industry using wired and mobile are grows rapidly. So P2P protocols will be used between mobile and wired network. But current P2P protocols are focused on the wired networks only and there are no simulators for performance analysis of mobile P2P. In this paper, we design a P2P simulation system for performance analysis of P2P protocols in mobile, wired and convergence networks. It is constructed by a well-known mobile network simulator and wired based P2P protocol simulator. Finally we have implemented a smart TV test-bed using our P2P test-bed for convergence networks.

수치해석기반의 동적 p-y 곡선 산정 (Evaluation of Dynamic p-y Curve Based on the Numerical Analysis)

  • 박정식;정상섬
    • 한국지반공학회논문집
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    • 제33권12호
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    • pp.59-73
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    • 2017
  • 3차원 유한요소 프로그램(PLAXIS 3D)를 이용한 수치해석을 통하여 동적표면하중 하에서지반-말뚝 구조물의 상호작용을 평가하였다. 수치해석에 의한 진동대 실험 형태의 하중조건 및 지반시스템에 대한 동적 p-y곡선을 산정하고 이를 통하여 말뚝-지반의 조건, 말뚝의 선단부 조건, 재하조건 등을 고려하여 매개변수 연구를 하였다. 그 결과 주파수 1.4Hz 입력 진동수가 모형 말뚝-지반 시스템의 고유진동수 1.4Hz와 거의 일치하여 공진 현상이 발생하여서 다른 진동수의 결과와 비교시 다른 p, y 값을 보이고 있다. P-y 곡선에서 이를 대표할 수 있는 경향선을 나타내는 3차 다항함수로 표현하여 결과를 정리하였다. 특히 단독 말뚝의 경우 지배적인 곡선의 형태가 수학적인 증명을 통해 타원(ellipse)임을 밝혀냈다. P-y곡선의형태가 타원인 경우는 타원 방정식을 직접 지반-구조물의 동적설계나 해석에 이용하는 것이 바람직하다고 판단된다.

No Association of the TGF-β1 29T/C Polymorphism with Breast Cancer Risk in Caucasian and Asian Populations: Evidence from a Meta-Analysis Involving 55, 841 Subjects

  • Alqumber, Mohammed A.A.;Dar, Sajad Ahmad;Haque, Shafiul;Wahid, Mohd;Singh, Rohit;Akhter, Naseem
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권20호
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    • pp.8725-8734
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    • 2014
  • The transforming growth factor-${\beta}1$ (TGF-${\beta}1$) gene 29 T/C polymorphism is thought to be associated with breast cancer risk. However, reports are largely conflicting and underpowered. We therefore conducted a meta-analysis of all available case-control studies relating the TGF-${\beta}1$ 29T/C polymorphism to the risk of developing breast cancer by including a total of 31 articles involving 24,021 cases and 31,820 controls. Pooled ORs were generated for the allele contrasts, with additive genetic, dominant genetic and recessive genetic models. Subgroup analysis was also performed by ethnicity for the TGF-${\beta}1$ 29T/C polymorphism. No association was found in the overall analysis (C vs T: OR=1.028, 95% CI=0.949-1.114, p-value 0.500; CC vs TC: OR= 1.022, 95% CI=0.963-1.085, p-value 0.478; CC vs TT: OR= 1.054, 95% CI=0.898-1.236, p-value 0.522; CC vs TT+ TC: OR= 1.031, 95% CI=0.946-1.124, p-value 0.482; TT vs CC+TC: OR= 0.945, 95% CI=0.827-1.080, p-value 0.403). Similarly, in the subgroup analysis by ethnicity, no association was found in Caucasian (C vs T: OR= 1.041, 95% CI=0.932-1.162, p-value 0.475; CC vs TC: OR= 1.031, 95% CI=0.951-1.118, p-value 0.464; CC vs TT: OR= 1.081, 95% CI=0.865-1.351, p-value 0.493; CC vs TT+TC: OR= 1.047, 95% CI=0.929-1.180, p-value 0.453; TT vs CC+TC: OR= 0.929, 95% CI=0.775-1.114, p-value 0.429;) and Asian populations (C vs T: OR= 1.004, 95% CI=0.908-1.111, p-value 0.931; CC vs TC: OR= 0.991, 95% CI=0.896-1.097, p-value 0.865; CC vs TT: OR= 1.015, 95% CI=0.848-1.214, p-value 0.871; CC vs TT+TC: OR= 1.000, 95% CI=0.909-1.101, p-value 0.994; TT vs CC+TC: OR= 0.967, 95% CI=0.808-1.159, p-value 0.720;). No evidence of publication bias was detected during the analysis. No significant association with breast cancer risk was demonstrated overall or on subgroup (Caucasian and Asian) analysis. It can be concluded that TGF-${\beta}1$ 29T/C polymorphism does not play a role in breast cancer susceptibility in overall or ethnicity-specific manner.

Association Between p53 codon 72 Polymorphism and Cervical Cancer Risk Among Asians: a Huge Review and Meta-analysis

  • Zhou, Xin;Gu, Yang;Zhang, Shu-Lan
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권10호
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    • pp.4909-4914
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    • 2012
  • Objective: The aim of this Human Genome Epidemiology (HuGE) review and meta-analysis was to derive a more precise estimation of the association between p53 codon 72 polymorphism (Arg72Pro, rs1042522 G>C) and cervical cancer risk among Asians. Methods: A literature search of Pubmed, Embase, Web of Science and CBM databases from inception through June 2012 was conducted. The meta-analysis was performed using STATA 12.0 software. Crude odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the strength of any association. Twenty-eight case-control studies were included with a total of 3,580 cervical cancer cases and 3,827 healthy controls. When all the eligible studies were pooled into the meta-analysis, the results showed that the Pro/Pro genotype was associated with increased risk of cervical cancer under the heterozygous model (Pro/Pro vs. Arg/Pro: OR = 1.25, 95%CI: 1.02-1.53, P= 0.005). However, no statistically significant associations were found under four other genetic models (Pro vs. Arg: OR = 0.97, 95%CI: 0.85-1.10, P= 0.624; Pro/Pro + Arg/Pro vs. Arg/Arg: OR = 0.84, 95%CI: 0.70-1.01, P= 0.058; Pro/Pro vs. Arg/Arg + Arg/Pro: OR = 1.13, 95%CI: 0.92-1.39, P= 0.242; Pro/Pro vs. Arg/Arg: OR = 0.97, 95%CI: 0.76-1.22, P= 0.765; respectively). In the subgroup analysis based on country, the Pro/Pro genotype and Pro carrier showed significant associations with increased risk of cervical cancer among Indian populations, but not among Chinese, Japanese and Korean populations. Conclusion: Results from the current meta-analysis suggests that p53 codon 72 polymorphism might be associated with increased risk of cervical cancer, especially among Indians.