• Biomolecules & Therapeutics
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• v.7 no.3
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• pp.242-248
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• 1999

Diazepam, a benzodiazepine (BDZ) agonist, produces sedation and flumazenil, a BDZ antagonist, blocks these actions. The aim of this study was to examine the effects of BDZs on cortical electroencephalogram (EEG) in rats. The recording electrodes were implanted over the frontal and parietal cortices bilaterally, and the reference and ground electrodes over cerebellum under ketamine anesthesia. To assess the effects of diazepam and flumazenil, rats were injected with diazepam (1 mgHg, i.p.) and/or flumazenil ( 1 mg/kg, i.p.), and the EEG was recorded before and after drugs. Normal awake had theta peak in the spectrum and low amplitude waves, while normal sleep showed large amplitude of slow waves. The powers of delta, theta and alpha bands were increased during sleep compared with during awake. Diazepam reduced the mobility of the rat and induced sleep with intermittent fast spindles and large amplitude of slow activity, and it produced broad peak over betaL band and increased the power of gamma band, which were different from EEG patterns in normal sleep. Saline injection awakened rats and abolished fast spindles for a short period about 2-5 min from EEG pattern during diazepam-induced sleep. Flumazenil blocked both diazepam-induced sleep and decreased the slow activities of delta, theta, alpha and betaL, but not of gamma activity for about 10 min or more. This study may indicate that decrease in power of betaL and betaH bands can be used as the measure of central action of benzodiazepines, and that the EEG parameters of benzodiazepines have to be measured without control over the behavioral state by experimenter.

• Physical Therapy Rehabilitation Science
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• v.11 no.3
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• pp.296-303
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• 2022

Objective: In general, macular degeneration, cataracts and glaucoma generally cause visual injury in clinical settings. This study aimed to examine the effects of low visual acuity simulations on hand manual dexterity function and brainwaves in healthy young adults. Design: Cross-sectional study design Methods: This study was an observational, cross-sectional study. Seventy healthy young adults participated in this study. To evaluate the effects of low visual acuity simulations on hand function and brain waves, this study involved four different visual conditions including (1) normal vision, (2) simulated cataracts, (3) simulated glaucoma, and (4) simulated macular degeneration. The hand function was measured to use the Minnesota manual dexterity test (MMDT), and the brainwaves was also measured to use the electroencephalography. Results: In hand function, placing and turning performance on the MMDT in the normal visual condition was significantly different than that in the cataract and macular degeneration conditions (p<0.05), and the placing performance was significantly differred in the normal condition than that in the simulated glaucoma. However, turning was not significantly different in the normal condition than that in the simulated glaucoma. The alpha, beta, and gamma waves did not significantly differ among the four visual conditions (p>0.05). Conclusions: The results suggest that limited visual information negatively affects the ability to perform tasks requiring arm-hand dexterity and eye-hand coordination. However, the effectiveness of low visual acuity on the brainwaves should be further studied for rehabilitative evidence of visual impairment.

• The Journal of Korean Physical Therapy
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• v.33 no.2
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• pp.106-113
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• 2021

Purpose: This study examined the effectiveness of action observation training (AOT) and mirror therapy in improving the electroencephalograms (EEG) of stroke patients. Methods: Patients were allocated randomly to three groups: an action observation training with activity (AOTA) group (n=12), a mirror therapy with activity (MTA) group (n=11), and an AOT-only group (n=12). All groups received conventional physiotherapy in five 60-minute sessions over six weeks. The AOTA, MTA, and AOT groups practiced AOTA, MTA, and AOT, respectively, in three 30-minute sessions over six weeks. The differences between the pre- and post-treatment EEGs were assessed using a paired t-test. Comparisons between the groups were performed using one-way ANOVA. Results: The participants in the AOTA and MTA groups showed significant improvement in the EEG. AOTA improved the alpha waves of the prefrontal, temporal, and parietal lobes significantly (p<0.05). MTA improved the alpha waves of the temporal lobe significantly (p<0.05). AOT did not result in significant improvement Conclusion: AOTA and MTA improve stroke patients' EEGs. Mirror neuron activation combined with conventional stroke physiotherapy promotes motor recovery and functioning. The effect is enhanced when the actions are executed after observation. Further research into mirror neuron activation will be needed to develop methods to improve the EEGs of stroke patients.

• Korean Journal of Adult Nursing
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• v.25 no.6
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• pp.644-654
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• 2013

Purpose: The purpose of this study was to examine the effects of aroma foot reflexology massage on mood states specifically depression and brain waves of elderly women with osteoarthritis. Methods: The study was a nonequivalent control group non-synchronized design. The participants were 62 elderly women with osteoarthritis. The instruments were the Korean-Profile of Mood States-Brief for mood states and 8-channel EEG (Electroencephalogram) system for brain waves. Data were collected from March to May, 2012. Twenty-six participants were assigned to the treatment group and twenty-six to the comparison group. The data were analyzed using SPSS/WIN 17.0 version program, and included descriptive statistics, t-test, and ANCOVA. The intervention was conducted three times a week for two weeks. Results: There were significantly improvement in reported depression. s. Brain waves (EEG) increased significantly in F3, T3 of ${\alpha}$ wave and in F4, T3, and P4 of ${\beta}$ wave between the two groups. Conclusion: Aroma foot reflexology massage can be utilized as an effective intervention to decrease depression of mood states, increase of ${\alpha}$, and ${\beta}$ brain wave on woman elderly with osteoarthritis.

• International Journal of Naval Architecture and Ocean Engineering
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• v.5 no.1
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• pp.161-177
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• 2013

High-speed vessels require good resistance and seakeeping performance for safe operations in rough seas. The resistance and seakeeping performance of high-speed vessels varies significantly depending on their hull forms. In this study, three planing hulls that have almost the same displacement and principal dimension are designed and the hydrodynamic characteristics of those hulls are estimated by high-speed model tests. All model ships are deep-V type planing hulls. The bows of no.2 and no.3 model ships are designed to be advantageous for wave-piercing in rough water. No.2 and no.3 model ships have concave and straight forebody cross-sections, respectively. And length-to-beam ratios of no.2 and no.3 models are larger than that of no.1 model. In calm water tests, running attitude and resistance of model ships are measured at various speeds. And motion tests in regular waves are performed to measure the heave and pitch motion responses of the model ships. The required power of no.1 (VPS) model is smallest, but its vertical motion amplitudes in waves are the largest. No.2 (VWC) model shows the smallest motion amplitudes in waves, but needs the greatest power at high speed. The resistance and seakeeping performance of no.3 (VWS) model ship are the middle of three model ships, respectively. And in regular waves, no.1 model ship experiences 'fly over' phenomena around its resonant frequency. Vertical accelerations at specific locations such as F.P., center of gravity of model ships are measured at their resonant frequency. It is necessary to measure accelerations by accelerometers or other devices in model tests for the accurate prediction of vertical accelerations in real ships.

• Journal of the Korean Geographical Society
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• v.41 no.5 s.116
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• pp.527-544
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• 2006

This study provides a definition of heat waves, which indicate the conditions of strong sultriness in summer, appropriate to Korea and intends to clarify long term(1973-2006) averaged spatial and temporal patterns of annual frequency of heat waves with respect to their intensity. Based on examination of the Korean mortality rate changes due to increase of apparent temperature under hot and humid summer conditions, three consecutive days with at least $32.5^{\circ}C,\;35.5^{\circ}C,\;38.5^{\circ}C,\;and\;41.5^{\circ}C$ of daily maximum Heat Index are defined as the Hot Spell(HS), the Heat Wave(HW), the Strong Heat Wave(SHW), and the Extreme Heat Wave(EHW), respectively. The annual frequency of all categories of heat waves is relatively low in high-elevated regions or on islands adjacent to seas. In contrast, the maximum annual frequency of heat waves during the study period as well as annual average frequency are highest in interior, low-elevated regions along major rivers in South Korea, particularly during the Changma Break period(between late July and mid-August). There is no obvious increasing or decreasing trend in the annual total frequency of all categories of heat waves for the study period However, the maximum annual frequencies of HS days at each weather station were recorded mainly in the 1970s, while most of maximum frequency records of both the HW and the SHW at individual weather stations were observed in the 1990s. It is also revealed that when heat waves occur in South Korea high humidity as well as high temperature contributes to increasing the heat wave intensity by $4.3-9.5^{\circ}C$. These results provide a useful basis to help develop a heat wave warning system appropriate to Korea.

• Structural Engineering and Mechanics
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• v.23 no.3
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• pp.233-247
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• 2006

Most codes of practice state that for large in-plane structures it is necessary to account for the spatial variability of earthquake ground motion. There are essentially three effects that contribute for this variation: (i) wave passage effect, due to finite propagation velocity; (ii) incoherence effect, due to differences in superposition of waves; and (iii) the local site amplification due to spatial variation in geological conditions. This paper discusses the procedures to be undertaken in the time domain analysis of a cable-stayed bridge under spatial variability of earthquake ground motion. The artificial synthesis of correlated displacements series that simulate the earthquake load is discussed first. Next, it is described the 3D model of the International Guadiana Bridge used for running tests with seismic analysis. A comparison of the effects produced by seismic waves with different apparent propagation velocities and different geological conditions is undertaken. The results in this study show that the differences between the analysis with and without spatial variability of earthquake ground motion can be important for some displacements and internal forces, especially those influenced by symmetric modes.

• Proceedings of the Korean Geotechical Society Conference
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• 2010.03a
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• pp.705-710
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• 2010

Bender element is made of connecting two piezoelectric elements which have different polarities from each other, and is a kind of sensors which can be used either way as a source making elastic wave or a receiver. Elastic waves generated by stimulating the bender elements can be decomposed to P-wave and S-wave propagation. Numerical and expeimental studies are conducted, and results show that multiple measurements are recommended to determine wave arrivals from the received signals.

• Journal of the Korean Institute of Navigation
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• v.23 no.2
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• pp.23-27
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• 1999

When a ship is running in following and quartering seas and on a crest with the ship′s length being nearly the same as the wave length, ship′s stability will be lost most; "T" shape crests with highly concentrated energy will appear during the process of transformation from irregular waves to regular ones, and the ship may be under continuous impact of large waves for a long period of time; Synchronism will also appear when the ship′s natural period of rolling and period of encounter are close to each other. For safe navigation, proper stability should be well ensured, proper speed and course chosen with speed under 1.8L1/2 kn (L is the ship′s length), initial listing avoided, special attention paid to steering.

• Proceedings of the Korean Geotechical Society Conference
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• 2005.03a
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• pp.302-307
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• 2005

Love wave and Rayleigh wave are the major elastic waves belonging to the category of the surface wave. The fact that Love wave is not contaminated by P-wave which makes Love wave superior to Rayleigh wave and other body waves. Therefore, the information that Love wave carries is more distinct and clearer than the information of Rayleigh wave. Based on theoretical research, the joint inversion analysis which is used both Love wave dispersion information and Rayleigh wave dispersion information was proposed. Purpose of the joint inversion analysis is to improve accuracy and convergency of inversion results utilizing that frequency contribution of each wave is different. This analysis technique is consisted of the forward modeling using transfer matrix, the sensitivity matrix determined to the ground system and DLSS(Damped Least Square Solution) as a inversion technique. The application of this analysis was examined through the field test.