• Radiation Oncology Journal
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• v.37 no.1
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• pp.22-29
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• 2019

Purpose: The aim of this study is to evaluate the efficacy and feasibility of four-field box whole brain radiotherapy (FB-WBRT) with tilting baseplate by comparing bilateral WBRT (B-WBRT). Methods and Materials: Between March 2016 and September 2018, 20 patients with brain metastases underwent WBRT using the four-field box technique. WBRT is performed with a dose of 30 Gy in 10 fractions daily. Two computed tomography simulations per person were performed. One was in the traditional supine position for B-WBRT and the other by applying the tilting acrylic supine baseplate to elevate the head by 40° for FB-WBRT. The B-WBRT used the field-in-field technique, which is the most commonly used method in our institution. The FB-WBRT comprised anterior, posterior, and bilateral beams. A wedge was applied in anterior and posterior fields to compensate for skull convexity. Results: The average of Dmean of both parotid glands was 10.2 Gy (range, 3.8 to 17.8 Gy) in B-WBRT and 5.4 Gy (range, 2.0 to 11.7 Gy) in FB-WBRT (p < 0.05). Compared to B-WBRT, FB-WBRT reduced the mean dose of the right and left parotid glands from 10.1 Gy to 4.9 Gy and from 10.4 Gy to 5.8 Gy, respectively (p < 0.05). Further, V₅, V₁₀, V₁₅, V₂₀, and V₂₅ for the parotid gland decreased significantly in FB-WBRT (p < 0.05). The Dmax and Dmean of lens decreased according to the dose-volume histogram. Conclusion: Compared to B-WBRT, FB-WBRT with a tilting baseplate is a simple and effective method that takes feature of noncoplanar beam to protect the parotid gland.

• The Journal of Engineering Geology
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• v.12 no.2
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• pp.203-214
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• 2002

The statistical model was introduced to satisfy various experimental condition on the sorption of heavy metals (Pb, Cu, Cd, and Zn) by bentonite. The Box-Behnken model designed statistically was applied to determine relative impact among three variables such as pH, HCO$_3$ contents and heavy metal concentrations on the sorption. The SAS program was used to obtain the statistical solution. The statistical surface response analysis indicates that initial concentration of heavy metals and pH have an important effect on the sorption, and bicarbonate is not a serious variable. The sorption capability about heavy metals of bentonite is in the order of Pb>Cu>Zn>Cd. The precipitation as hydroxyl and carbonate complexes of heavy metals was thermodynamically analyzed as major mechanism of sorption under alkaline pHs and high bicarbonate solution. It was found that there is a little difference between the model prediction on the precipitation of heavy metals and the results of batch sorption experiment. The thermodynamic data of the programs have to revise to obtain the best fit condition between the model prediction and the experimental results.

• International Journal of CAD/CAM
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• v.3 no.1_2
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• pp.85-95
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• 2003

During the design of dies and molds, the cavity of the object is obtained by subtracting it from a surrounding rectangular block. This box is subsequently split into two halves by the parting surface. Similar problems also occur in some RP processes such as LOM, SGC, SLS and 3DP where the machine produces a block inside which the prototype is buried. Determining the orientation of the object inside the box and the corresponding parting surface taking appropriate constraints into account have been addressed by several researchers. However, given the parting surface, the problem of splitting the box development of a software package called OptiLOM (now a module of an RP software Magics 8.0), the authors realized non-triviality of this problem since the loop can spread over as many as 5 faces of the box. In this paper, the authors have tried to bring out the importance of this problem and have presented their algorithm to solve it.

• Computers and Concrete
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• v.20 no.5
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• pp.617-625
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• 2017

Prestress force identification (PFI) is crucial to maintain the safety of prestressed concrete bridges. A synergic identification method has been proposed recently by the authors that can determine the prestress force (PF) and the excitation force simultaneously in prestressed concrete beams with good accuracy. In this paper, the ability of this method in the application with prestressed concrete box-girder bridges is demonstrated. A reasonable assumption is made to capture the similarity of the dynamic behavior of the prestressed concrete box-girder bridge and a beam under a certain loading scenario, and the feasibility of this method for application in a prestressed box-girder bridge is affirmed. A comprehensive laboratory test program is conducted, and the effects of PF, excitation, measuring time and uncertainties are studied. Results show that the proposed method can predict the PF and the excitation force in a prestressed concrete box-girder accurately and has a great robustness against uncertainties.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.16 no.28
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• pp.31-37
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• 1993

Box-Jenkins models have some important limitations to the procedure : (a) They require a great deal of time, efforts and expertise for the model identification. (b) They require an extensive amount of past observations to identify an acceptable model. (c) The model selected is a constant model in time. Therefore, the Kalman Filter is recommended as a technique to overcome the three problems mentioned above. The research reported here uses the Kalman Filter algorithm to propose Kalman-AR(p) model. The data analysis shows that the Kalman-AR(p) model proposed can be used to resolve the problems of Box-Jenkins AR(p)model. It is seen that the Kalman Filter has great potentials for real-time industrial applications.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1997.04a
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• pp.106-113
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• 1997

Until now, the evaluation of prestressing force during the survice state has received limited attention. Only initial prestressing force is estimated by reading the pressure values of a hydraulic jack or by observing the initial elongation of tendons. In this study, the initial losses and time dependent losses of prestressing force have been monitored by installing 12 vibrating wire-type load cells at the part of P.C. box bridge of Gangbyun Riverside Highway. Also comparative study was made for measured prestressing losses and estimated values. 2-dimensional analysis was performed to see the trend of prestressing losses, and the results was compared with measured ones.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.29 no.2
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• pp.143-149
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• 1996

Forecasts of the monthly catches of anchovy in Korea were carried out by the seasonal Autoregressive Integrated Moving Average (ARIMA) model and spectral analysis. The seasonal ARIMA model is as follows: $$(1-0.431B)(1-B^{12})Z_t=(1-0.882B^{12})e_t$$ where: $Z_t=value$ at month $t;\;B^{p}$ is a backward shift operator, that is, $B^pZ_t=Z_{t-p};$ and $e_t=error$ term at month t, which is to forecast 24 months ahead the anchovy catches in Korea. The prediction error by the Box-Cox transformation on monthly anchovy catches in Korea was less than that by the logarithmic transformation. The equation of the Box-Cox transformation was $Y'=(Y^{0.58}-1)/0.58$. Forecasts of the monthly anchovy catches for $1991\~1992$, which were compared with the actual catches, had an absolute percentage error (APE) range of $1.0\~63.2\%$. Total observed annual catches in 1991 and 1992 were 170,293 M/T and 168,234 M/T respectively, while the predicted catches were 148,201 M/T and 148,834 M/T $(API\;13.0\%\;and\;11.5\%,\;respectively)$. The spectrum analysis of the monthly catches of anchovy showed some dominant fluctuations in the periods of 2.2, 6.1, 10.2 12.0 and 14.7 months. The spectrum analysis was also useful for selecting the ARIMA model.

• Food Science and Preservation
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• v.24 no.2
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• pp.159-167
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• 2017

This study was investigated the effects of maintaining the freshness and stabilization of supply and demand for lettuce (Lactuca sativa L.) by packaging methods in summer. Post-harvest lettuces were packaged by corrugated box, polypropylene (P) box, and individual wrapping using polyvinyl chloride (PVC) film. Then, the lettuce samples were stored at $2^{\circ}C$ and evaluated the change of quality during storage. The lettuces wrapped individually with PVC film had lower weight loss rate, color change, and browning index compared to lettuces packaged by corrugated box and P box. The SPAD value and hardness were higher in lettuces wrapped individually with PVC film than other packaging methods. The lettuces wrapped individually with PVC film were showed the highest total phenolic contents and DPPH radical scavenging activity, but there were no significantly differences by packaging methods. The lettuces packaged by corrugated box were showed the inside browning after 14 days. However, the lettuces wrapped individually with PVC film were showed the best appearance. Therefore, the packaging method of wrapped individually with PVC film were effective in maintaining the freshness during 21 days and helpful for the stabilization of supply and demand for lettuce in summer.

• Journal of the Korea Safety Management & Science
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• v.11 no.3
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• pp.79-85
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• 2009

In this study, the effects of psychosocial stress (box color and precision demand) on muscle activity were evaluated in laboratory setting. Eight subjects performed sagittally symmetric lifting tasks. Box color (yellow, black), precision demand (yes, no), and box weight (5%MVC, 10%MVC, 15 %MVC) were varied and surface EMG signals from seven muscles(medial deltoid right, biceps brachii right, lateral triceps right, latissimus dorsi right, erector spinae right, external oblique right, internal oblique right) were recorded. EMG signals were band-pass filtered($10{\sim}400\;Hz$), rectified, RMS smoothed and normalized (NEMG). Analysis of variance tests were conducted on the total NEMG (TNEMG: the sum of the seven muscles' NEMGs) and on the individual muscle's NEMGs. Box color had no effect on the TNEMG and on the seven muscles activities(p>0.05). When precision demand was required at the end point of lifts, the mean NEMG showed higher values than no precision demand conditions: TNEMG (14% increase) and medial deltoid(40% increase), biceps brachii(10% increase), lateral triceps(26% increase), latissimus dorsi(25% increase) muscles. Those increases showed more conspicuous as the box weight increased in the muscles of medial deltoid, lateral triceps, and latissimus dorsi.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.24
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• pp.10621-10625
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• 2015

Background: Increasing evidence has indicated that high Forkhead box protein C2 (FOXC2) level is closely associated with the development, progression, and poor prognosis of a variety of tumors. However, the relationship between FOXC2 and the progression of human gliomas remains to be clarified. The aim of present study was to assess FOXC2 expression and to explore its contribution in human gliomas. Materials and Methods: Realtime quantitative PCR was performed to examine FOXC2 expression in 85 pairs of fresh frozen glioma tissues and corresponding non-neoplastic brain tissues. Associations of FOXC2 expression with clinicopathological factors and prognosis of glioma patients were statistically analyzed. Results: The relative mRNA expression of FOXC2 was significantly higher in glioma tissues than the corresponding non-neoplastic brain tissues (p<0.001). In addition, high FOXC2 expression was significantly associated with advanced pathological grade (P=0.005) and the low Karnofsky performance score (KPS) (p=0.003), correlating with poor survival (p<0.001). Furthermore, multivariate Cox regression analysis showed that high FOXC2 expression was an independent predictor of overall survival (p=0.006). Conclusions: FOXC2 may act as an oncogenic gene and represent a potential regulator of aggressive development and a candidate prognostic marker in human gliomas.