• Title/Summary/Keyword: P-V value

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Dosimetric Comparison of Three-Dimensional Conformal, Intensity-Modulated Radiotherapy, Volumetric Modulated Arc Therapy, and Dynamic Conformal Arc Therapy Techniques in Prophylactic Cranial Irradiation

  • Ismail Faruk Durmus;Dursun Esitmez;Guner Ipek Arslan;Ayse Okumus
    • Progress in Medical Physics
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    • v.34 no.4
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    • pp.41-47
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    • 2023
  • Purpose: This study aimed to dosimetrically compare the technique of three-dimensional conformal radiotherapy (3D CRT), which is a traditional prophylactic cranial irradiation method, and the intensity-modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) techniques used in the last few decades with the dynamic conformal arc therapy (DCAT) technique. Methods: The 3D CRT, VMAT, IMRT, and DCAT plans were prepared with 25 Gy in 10 fractions in a Monaco planning system. The target volume and the critical organ doses were compared. A comparison of the body V2, V5, and V10 doses, monitor unit (MU), and beam on-time values was also performed. Results: In planned target volume of the brain (PTVBrain), the highest D99 dose value (P<0.001) and the most homogeneous (P=0.049) dose distribution according to the heterogeneity index were obtained using the VMAT technique. In contrast, the lowest values were obtained using the 3D CRT technique in the body V2, V5, and V10 doses. The MU values were the lowest when DCAT (P=0.001) was used. These values were 0.34% (P=0.256) lower with the 3D CRT technique, 66% (P=0.001) lower with IMRT, and 72% (P=0.001) lower with VMAT. The beam on-time values were the lowest with the 3D CRT planning (P<0.001), 3.8% (P=0.008) lower than DCAT, 65% (P=0.001) lower than VMAT planning, and 76% (P=0.001) lower than IMRT planning. Conclusions: Without sacrificing the homogeneous dose distribution and the critical organ doses in IMRTs, three to four times less treatment time, less low-dose volume, less leakage radiation, and less radiation scattering could be achieved when the DCAT technique is used similar to conventional methods. In short, DCAT, which is applicable in small target volumes, can also be successfully planned in large target volumes, such as the whole-brain.

Determination of empirical formula for instantaneous heat transfer coefficients in a S. I. engine (스파크 점화기관의 순간열전달계수의 경험식 결정)

  • Han, Seong-Bin;Gwon, Yeong-Jik;Lee, Jeong-Yeol
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.21 no.11
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    • pp.1475-1484
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    • 1997
  • A new empirical formula for instantaneous heat transfer coefficients was determined. The determination of this formula is in need for prediction of instantaneous value of heat transfer coefficients to analyze in more detail the time variation of heat transfer rate from gas to wall in combustion chamber of a spark ignition engine. As the result, following formula was determined. h=687 $p^{0.75}$ $U^{0.75}$ $D^{0.25}$ - $T^{-0.465}$ U(.theta.)=O.494 $V_{p}$ +0.73*10$^{6}$ (1.35 p dV/d.theta.+V dp/d.theta.) Using this empirical formula, the instantaneous heat transfer coefficients of gas in the combustion chamber of spark ignition engine was predicted and compared with experimental values.

Fabrication and Evaluation of AC 400 kV High Voltage Divider using Electric Field Sensor (전기장 센서를 이용한 교류 400 kV 고전압 분압기의 제작 및 평가)

  • Lee, Sang-Hwa;Han, Sang-Gil;Jung, Jae-Kap;Kang, Jeon-Hong;Kim, Yoon-Hyoung;Jeong, Jin-Hye;Han, Sang-Ok
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.57 no.3
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    • pp.265-269
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    • 2008
  • Output voltage value of AC high voltage source has usually been obtained by measuring the low arm voltage of high voltage divider or the secondary voltage of high voltage transformer. In this study, we have fabricated the AC 400 kV high voltage divider using high voltage electrode and electric field measurement sensor. The dividing ratio of the fabricated 400 kV high voltage divider was evaluated using reference 400 kV capacitive divider. The dividing ratio of 400 kV high voltage divider is found to be 12,322 and has the good linearity within 0.63 % against AC high voltage up to 400 kV. Therefore, the developed 400 kV high voltage divider could evaluate 400 kV high voltage supply and voltage divider used in industry.

Evaluation for Marine Ground in Pusan Area using PMT (공내재하시험을 이용한 부산지역 해저지반의 평가)

  • 김동철;최용규
    • Proceedings of the Korean Geotechical Society Conference
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    • 2000.03b
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    • pp.338-345
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    • 2000
  • In this study, applicability of PMT in domestic area and test procedure were studied. At six test holes of three construction sites in Pusan, PMT using Elastometer-200 type was done. The problems during test were investigated and the test results were analysed. Limit pressure, p$\sub$ι/ could be determined by p- Δv/v method. Using PMT results, marine soil in Pusan could be classified approximately. Net limit pressure value was in the range of 6.4 ∼ 22.5 kg/$\textrm{cm}^2$ in clay, 2.2 ∼ 30.0 kg/$\textrm{cm}^2$ in sand, 13.0 ∼ 58.0 kg/$\textrm{cm}^2$ in weathered soil and 47.0 ∼ 190.0 kg/$\textrm{cm}^2$ in weathered rock. Also, E$\sub$m//p$\sub$ι/ value was in the range of 2.4 ∼ 7.0 in clay, 2.6 ∼ 12.1 in sand, 6.8 ∼ 17.1 in weathered soil and 7.2 ∼ 29.6 in weathered rock.

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Effect of Scoparone on the Hepatic Microsomal UDPglucuronyltransferase Activity in Mice

  • Huh, Keun;Lee, Sang-Il;Park, Jong-Min
    • Archives of Pharmacal Research
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    • v.10 no.3
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    • pp.165-168
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    • 1987
  • The effect of scoparone on UDP glucuronyltransfearase in mouse hepatic microsomes was studied. After transment with scoparone, hepatic microsomal UDP glucuronyltransferase activity was increased with dose-dependent manner as compared to control. The V$_max$ value (control = 23.2 n moles/mg protein/min, scoparone = 31.2 n moles/ mg protein /min) without affecting the $K_m$ value (414 $\mu$M) for p-nitrophenol was increased by the scoparone treatment, and the pattern of kinetic studies for UDP-glucuronic acid was also similar to those of p-nitrophenol. Whereas, the hepatic microsomal UDP glucuronyl-transferase was not changed by the addition of scoparone in vitro. The results obtained suggest that the characteristics of increase in the enzyme activity may include induction of enzyme proteins.

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Characteristics of Ultra-thin Polymer Ferroelectric Films (초박막 폴리머 강유전체 박막의 특성)

  • Kim, Kwang-Ho
    • Journal of the Semiconductor & Display Technology
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    • v.19 no.4
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    • pp.84-87
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    • 2020
  • The properties of ultra-thin two-dimensional (2D) organic ferroelectric Langmuir-Blodgett (LB) films of the poly(vinylidene fluoride-trifluoroethylene) [P(VDF-TrFE)] were investigated to find possible applicability in flexible and wearable electronics applications. In the C-V characteristics of the MFM capacitor of 2-monolayer of 5 nm films, a butterfly hysteresis curve due to the ferroelectricity of P(VDF-TrFE) was confirmed. Typical residual polarization value was measured at 2μC/㎠. When the MFM capacitor with ultra-thin ferroelectric film was measured by applying a 10 Hz bipolar pulse, it was shown that 65% of the initial polarization value in 105 cycles deteriorated the polarization. The leakage current density of the 2-monolayer film was maintained at about 5 × 10-8 A/㎠ for the case at a 5MV/cm electric field. The resistivity of the 2-monolayer film in the case at an electric field at 5 MV/cm was more than 2.35 × 1013 Ω·cm.

CHEMICAL COMPOSITION AND NUTRITIVE VALUE OF THE Gliricidia sepium PROVENANCES IN DRYLAND FARMING AREA IN BALI, INDONESIA

  • Sukanten, I.W.;Uchida, S.;Nitis, I.M.;Lana, K.;Putra, S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.8 no.3
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    • pp.231-239
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    • 1995
  • Alley cropping field experiment has been carried out for 24 months in lime-stone based dryland farming area of southern Bali to study the chemical composition and nutritive value of 16 provenances of Gliricidia sepium The design was a completely randomized block: arrangement, consisted of 16 treatments (G. sepium provenances) and 6 blocks as replications with 12 plants per provenance. Of the 16 gliricidia provenances, six were from Mexico (M), four were from Guatemala (G), one each was from Colombia (C), Indonesia (I), Nicaragua (N), Panama (P), Costa Rica (R) and Venezuela (V). After 12 months establishment, the gliricidia were lopped at 150 cm height regularly 4 times a year, twice during the 4 months wet season and twice during the 8 months dry season. The highest ash, mineral, total soluble phenol, prussic acid and digestibility were in V1; the highest crude fiber component was in M39; the highest gross energy was in P13, while the highest organic matter was in M35. Based on the highest nutritive constituents, V1, C24 and G14 were ranked first, second and third respectively, while based on the lowest non-nutritive constituents C24, V1 and N14 were ranked first, second and third, respectively. The importance of such provenances as source of nutrients for the ruminant during the dry season were discussed.

Photocatalytic Oxidation of 2-Mercaptoethanol to Disulfide using Sb(V)-, P(V)-, and Ge(IV)-porphyrin Complexes

  • Shiragami, Tsutomu;Onitsuka, Dai;Matsumoto, Jin;Yasuda, Masahide
    • Rapid Communication in Photoscience
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    • v.3 no.4
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    • pp.70-72
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    • 2014
  • Visible-light irradiation of MeCN solution containing di(hydroxo)metallo(tetraphenyl)porphyrin complex $(tppM(OH)_2$: 1a; $M=Sb(V)^+Br^-$, 1b; $M=P(V)^+Cl^-$, 1c; M=Ge(IV)) and 2-mercaptoethanol (2-ME) as a substrate under aerated condition gave bis(2-hydroxyethyl)disulfide (2-HEDS) as an oxidative product of 2-ME. It is indicated that the oxidation of 2-ME should proceed with a photocatalytic process by 1, because the turn over number (TON) for the formation of 2-HEDS was over unit. The TON was determined to be 642 as a maximum value when 1a was used as a sensitizer. The formation of 2-HDES was extremely slow under argon atmosphere. The fluorescence of 1 was not quenched by 2-ME at all, and the free energy change (${\Delta}G$) with electron transfer (ET) from 2-ME to excited triplet state of $1(^31^*)$ was estimated as a negative value. The quenching rate constant ($k_r$) of $^31^*$ by 2-ME, obtained by the kinetics for the formation of 2-HEDS, strongly depends on ${\Delta}G$. These findings indicate that 1-sensitized oxidation was initiated by photoinduced ET from 2-ME to $^31^*$ to generate both radical cation of 2-ME ($2-ME^{+\bulle}$) and porphyrin radical anion ($1^{-\bulle}$), resulting that the formation of 2-HEDS can be proceeded by the dimerization of $2-ME^{+\bulle}$, and through a catalytic cycle due to returning to 1 by the ET from $1^{-\bulle}$ to molecular oxygen.

Effect of Nanopowdered Peanut Sprouts on Physicochemical and Sensory Properties of Milk

  • Ahn, Yu-Jin;Ganesan, Palanivel;Kwak, Hae-Soo
    • Food Science of Animal Resources
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    • v.33 no.1
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    • pp.9-15
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    • 2013
  • A study was conducted to examine the physicochemical and sensory properties of milk supplemented with nanopowdered peanut sprouts (NPPS) at different concentrations (1, 3, 5, 7, and 9%, w/v) during the storage at $4^{\circ}C$ for 16 d. The size of NPPS ranged from 300-350 nm as observed by the particle size analyzer. The pH values of all samples ranged from 6.8 to 6.6 during the storage of 16 d. In color, the $L^*$ value of milk samples were not remarkably influenced by NPPS supplementation, whereas the $b^*$ and $a^*$ values significantly increased with the NPPS supplementation at all concentrations at 0 d storage, due to the original yellow color of NPPS powder (p<0.05). DPPH study revealed that higher antioxidant activity of milk supplement with higher concentrations of NPPS. TBARS value found to lower at the lower concentrations (1 and 3%, w/v) of NPPS supplementation. The sensory test revealed that the overall acceptability scores of NPPS supplemented milk samples (1 and 3%, w/v) were quite similar to control throughout the storage period of 16 d. Based on the data obtained from the present study, it was concluded that the concentrations (1 and 3%, w/v) of NPPS could be used to produce NPPS-supplemented milk without significant adverse effects on physicochemical and sensory properties, and enhance functional components from the supplementation.

글루타치온 생산효소( $\gamma$-Glutamylcysteine Synthetase)와 그 변이효소의 구조분석 및 반응 Kinetics 연구

  • Yang, Hye-Jeong;Gwon, Dae-Yeong
    • Bulletin of Food Technology
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    • v.17 no.4
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    • pp.98-106
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    • 2004
  • Two mutant enzymes of $\gamma$-glutamylcysteine synthetase ($\gamma$-GCS) which catalyzed the synthesis of $\gamma$-glutamylcysteine from L-glutamic acid and L-cysteine in the presence of ATP, were prepared bypoint mutation of $\gamma$-GCS gene with site-directed mutagensis in E. coli. Conformational structuresand catalytic reaction kinetics of mutant enzymes were compared with wild type $\gamma$-GCS afterpurification. The S495F mutant enzyme (serine at 495 residue was substituted with phenylalanine),which had no catalytic activity for $\gamma$-glutamylcysteine synthesis, rarely folded even in neutral pH.However, the mutant A494V (alanine of 494 residue was replaced by valnine) which showed 50 %increase of activity, had a high folding structure. The folding structure of A494V also more stable athigh temperature and extreme pH compared to wild type and S495F. Reaction kinetics of wild typeand A494V were also investigated, Km value of A494V was smaller than that of wild type, while itshowed a little difference at Vmax values. This result evolved that alanine at 494 may be involved inbinding site of substrate rather than catalytic site. In addition, change of catalytic activity by onepoint mutation was highly correlated with the folding structure of enzyme.

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