• 제목/요약/키워드: P-${\Delta}$ effects

검색결과 397건 처리시간 0.026초

Numerical Investigation of Flow-pattern and Flow-induced Noise for Two Staggered Circular Cylinders in Cross-flow by LBM

  • Kim, Jeong-Whan;Oh, Sae-Kyung;Kang, Ho-Keun
    • Journal of Advanced Marine Engineering and Technology
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    • 제32권1호
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    • pp.82-93
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    • 2008
  • The flowfield behind two cylinders and flow-induced noise generated from the cylinders in various arrangement are numerically investigated based on the finite difference lattice Boltzmann model with 21 velocity bits. which is introduced a flexible specific heat ${\gamma}$ to simulate diatomic gases like air. In an isolated cylinder with two type of mesh. some flow parameters such as Strouhal number $S_t$ and acoustic pressure ${\Delta}p$ simulated from the solution are given and quantitatively compared with those provided the previous works. The effects of the center-to-center pitch ratio $L_{cc}/d=2.0$ in staggered circular cylinders as shown in Fig. 1 and angles of incidence ${\alpha}=30^{\circ}(T_{cc}/d=0.5)$, $45^{\circ}(T_{cc}/d =0.707)$ and $60^{\circ}\;(T_{cc}/d=0.866)$, respectively, are studied. Our analysis focuses on the small-scale instabilities of vortex shedding, which occurs in staggered arrangement. With the results of drag $C_d$ and lift $C_l$ coefficients and vorticity contours. the mechanisms of the interference phenomenon and its interaction with the two-dimensional vortical structures are present in the flowfields under $Re\;{\le}\;200$. The results show that we successively capture very small pressure fluctuations, with the same frequency of vortex shedding, much smaller than the whole pressure fluctuation around pairs of circular cylinders. The upstream cylinder behaves like an isolated single cylinder, while the downstream one experiences wake-induced flutter. It is expected that, therefore, the relative position of the downstream cylinder has significant effects on the flow-induce noise, hydrodynamic force and vortex shedding characteristics of the cylinders.

Peroxisome Proliferator-Activated Receptor α Facilitates Osteogenic Differentiation in MC3T3-E1 Cells via the Sirtuin 1-Dependent Signaling Pathway

  • Gong, Kai;Qu, Bo;Wang, Cairu;Zhou, Jingsong;Liao, Dongfa;Zheng, Wei;Pan, Xianming
    • Molecules and Cells
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    • 제40권6호
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    • pp.393-400
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    • 2017
  • Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease characterized by lack of insulin and high glucose levels. T2DM can cause bone loss and fracture, thus leading to diabetic osteoporosis. Promoting osteogenic differentiation of osteoblasts may effectively treat diabetic osteoporosis. We previously reported that Sirtuin 1 (Sirt1), a $NAD^+$-dependent deacetylase, promotes osteogenic differentiation through downregulation of peroxisome proliferator-activated receptor (PPAR) ${\gamma}$. We also found that miR-132 regulates osteogenic differentiation by downregulating Sirt1 in a $PPAR{\beta}/{\delta}$-dependent manner. The ligand-activated transcription factor, $PPAR{\alpha}$, is another isotype of the peroxisome proliferator-activated receptor family that helps maintain bone homeostasis and promot bone formation. Whether the regulatory role of $PPAR{\alpha}$ in osteogenic differentiation is mediated via Sirt1 remains unclear. In the present study, we aimed to determine this role and the underlying mechanism by using high glucose (HG) and free fatty acids (FFA) to mimic T2DM in MC3T3-E1 cells. The results showed that HG-FFA significantly inhibited expression of $PPAR{\alpha}$, Sirt1 and osteogenic differentiation, but these effects were markedly reversed by $PPAR{\alpha}$ overexpression. Moreover, siSirt1 attenuated the positive effects of $PPAR{\alpha}$ on osteogenic differentiation, suggesting that $PPAR{\alpha}$ promotes osteogenic differentiation in a Sirt1-dependent manner. Luciferase activity assay confirmed interactions between $PPAR{\alpha}$ and Sirt1. These findings indicate that $PPAR{\alpha}$ promotes osteogenic differentiation via the Sirt1-dependent signaling pathway.

잎채소 분말을 첨가한 초콜릿의 품질특성 및 항산화 활성 (Quality Properties and Antioxidant Activities of Chocolate with Variable Leaf Powder)

  • 오현빈;송가영;장양양;정기영;신소연;김영순
    • 한국식품조리과학회지
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    • 제33권3호
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    • pp.247-255
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    • 2017
  • Purpose: The aim of this study was to investigate the effects of various leaf powders on chocolate by analyzing quality characteristics, antioxidant activities, and sensory characteristics. Methods: Pine needles, mulberry leaves, ramie leaves, barley leaves, and squash leaves were freeze-dried, powdered, and added to the chocolate. Results: Water contents of all leaf powder-added groups were significantly higher than that of the control (15.78%). The pH values of chocolate with leaf powder were lower than that of the control (6.33) while that of mulberry leaf chocolate (6.56) was higher than that of the control. In color measurement, L-value, a-value, and b-value were highest in pine needle chocolate (30.31, 3.52, and 4.78, respectively). The ${\Delta}E$ value (total color difference compared to white board) was the highest in squash leaf chocolate (69.51) and significantly different from that of the control (67.69). The hardness of leaf powder-added chocolate was lower than that of the control (6.84 N), except for pine needles. In the antioxidant activity analysis, chocolate with pine needles and squash leaves had higher polyphenols, flavonoids, and ABTS radical scavenging antioxidant activity than those of the control. Overall consumer acceptability was the most preferred in the control compared to the other groups. However, chocolate with mulberry and barley leaves also received high scores (5.60 and 5.40, respectively) for overall acceptability. Conclusion: It can be concluded that chocolate with barley leaves is desirable for making functional chocolate due to its high consumer preference and positive effects on improving antioxidant activities.

Thermal Curing Behavior and Tensile Properties of Resole Phenol-Formaldehyde Resin/Clay/Cellulose Nanocomposite

  • Park, Byung-Dae;Kadla, John F.
    • Journal of the Korean Wood Science and Technology
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    • 제40권2호
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    • pp.110-122
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    • 2012
  • This study investigated the effects of layered clay on the thermal curing behavior and tensile properties of resole phenol-formaldehyde (PF) resin/clay/cellulose nanocomposites. The thermal curing behavior of the nanocomposite was characterized using conventional differential scanning calorimetry (DSC) and temperature modulated (TMDSC). The addition of clay was found to accelerate resin curing, as measured by peak temperature ($T_p$) and heat of reaction (${\Delta}H$) of the nanocomposite’ curing reaction increasing clay addition decreased $T_p$ with a minimum at 3~5% clay. However, the reversing heat flow and heat capacity showed that the clay addition up to 3% delayed the vitrification process of the resole PF resin in the nanocomposite, indicating an inhibition effect of the clay on curing in the later stages of the reaction. Three different methods were employed to determineactivation energies for the curing reaction of the nanocomposite. Both the Ozawa and Kissinger methods showed the lowest activation energy (E) at 3% clay content. Using the isoconversional method, the activation energy ($E_{\alpha}$) as a function of the degree of conversion was measured and showed that as the degree of cure increased, the $E_{\alpha}$ showed a gradual decrease, and gave the lowest value at 3% nanoclay. The addition of clay improved the tensile strengths of the nanocomposites, although a slight decrease in the elongation at break was observed as the clay content increased. These results demonstrated that the addition of clay to resole PF resins accelerate the curing behavior of the nanocomposites with an optimum level of 3% clay based on the balance between the cure kinetics and tensile properties.

내관 전침 자극이 뇌파에 미치는 영향 (The Effect of Electroacupuncture at the PC6 (Naegwan) on the EEG)

  • 이태영;김영안;이광규;육상원;이창현;이상룡
    • Journal of Acupuncture Research
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    • 제19권3호
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    • pp.26-40
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    • 2002
  • Objective : The aim of this study was to examine the effects of electroacupuncture(EA) at the PC6 (Naegwan) on nomal humans using power spectrum analysis. Methods : Electroencephalogram(EEG) is a multi-scaled signal consisting of several components of time series with different dominant frequency ranges and different origins. EEG power spectrum exibit site-specific and state-related differences in specific frequency bands. In this study, power spectrum was used as a measure of complexity. 30 channel EEG study was carried out in 8 subjects (8 males; age=$21.4{\pm}0.5$ years). Results : We found that the power values of the alpha wave at F7 channel (P<0.05) were highered than during the acupuncture treatment, and the power values of the delta wave at TCP1, CP1, TCP2, T5 channels(P<0.05) were lowered than during the acupuncture treatment. However, the comparison with that before and after the treatment shows no significant differences in all channels.

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Effect of Organic Acids on Cr(III) Oxidation by Mn-oxide

  • Chung, Jong-Bae
    • Applied Biological Chemistry
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    • 제41권4호
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    • pp.241-245
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    • 1998
  • Two oxidation states of chromium commonly occur in natural soil/water systems, Cr(III) and Cr(VI). The oxidized form, Cr(VI), exists as the chromate ion and is more mobile and toxic than Cr(III). Therefore oxidation of Cr(III) by various Mn-oxides in natural systems is a very important environmental concern. Organic substances can inhibit the Cr(III) oxidation by binding, Cr(III) strongly and also by dissolving Mn-oxides. Most of Cr(III) oxidation studies were carried out using in vitro systems without organic substances which exist in natural soil/water systems. In this study effect of organic acids - oxalate and pyruvate - on Cr(III) oxidation by $birnessite({\delta}-MnO_2)$ was examined. The two organic acids significantly inhibited Cr(III) oxidation by birnessite. Oxalate showed more significant inhibition than pyruvate. As solution pH was lowered in the range of 3.0 to 5.0, the Cr(III) oxidation was more strongly depressed. Addition of more organic acids reduced the Cr(III) oxidation mare extensively. Different inhibition effects by the organic acids could be due to their ability of reductive dissolution of Mn-oxides and/or Cr(III) binding. Organic acids dissolved Mn-oxide during the Cr(III) oxidation by the oxide, Dissolution by oxalic acid was much greater than that by pyruvate, and the dissolution was more extensive at lower pH. Inhibition of Cr(III) oxidation was parallel to the dissolution of Mn-oxide by organic acids. Although the effect of Cr(III) binding by organic acids on Cr(III) oxidation is not known yet, Mn-oxide dissolution by organic acids could be a main reason for the inhibition of Cr(III) oxidation by Mn-oxide in presence of organic acids. Thus oxidation of Cr(III) to Cr(VI) by various Mn-oxides in natural systems could be much less than the oxidation estimated by in vitro studies with only Cr(III) and Mn-oxides.

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오이 잎에서 저온 광저해에 의한 형광유도과정의 초기 변이와 스트레스 지표 (Early Alterations of Chlorophyll Fluorescence by Light-Chilling in Cucumber (Cucumis sativus) Leaves and Their Usage as Stress Indicators)

  • Ha, Suk-Bong;Young-Jae Eu;Choon-Hwan Lee
    • The Korean Journal of Ecology
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    • 제19권2호
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    • pp.151-163
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    • 1996
  • To investigate the early symptoms of light-chilling, alterations of chlorophyll fluorescence transients were monitored in cucumber (Cucumis sativus L. cv. Ilmichungjang) leaves. During 24 h chilling, decreases in (Fv)m/Fm, qE and qQ, and an increase in Fo were observed. The chilling effects were not recovered at room temperature, and a significant increase in Fo was observed during the recovery period. After 6 h chilling, ‘dip’(D) level of the transients became obscure, and the negative slope after ‘peak’(P) disappeared. The first derivative (dFv/dt) of the fast fluorescence rise curve was used to obtain more accurate information about the changes in the transients. The maximal rate of the fluorescence increase in the D-p rise curve (Fr) has been the most frequently used chilling stress indicator. However, a correct value of Fr could not be measured when the D level became obscure. This problem was overcome by introducing a new indicator, HFr (dFv/dt at Fv = 1/2 (Fv)m), and HFr gave very similar values to Fr. To monitor the changes in curvature around D level, another new parameter, ${\Delta}S$(D-Fr), was also introduced. These three parameters decreased very sensitively during light-chilling. In addition, increases in these parameters were observed during the first 2 h chilling, but this increase in Fr was also observed in pea leaf discs dark-chilled for 15 min, suggesting that this very early change is a common response to chilling in both pea and cucumber leaves. Quenching coefficients were also very sensitive to chilling, especially qE. Discussion on the usage of these parameters as chilling stress indicators is given in the text.

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가공조건이 명태어분단백질 필름의 인장강도와 색에 미치는 영향 (Effects of processing conditions on tensile properties and color of Alaska Pollack meal protein isolate film)

  • 유병진;심재만
    • 한국수산과학회지
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    • 제33권5호
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    • pp.418-422
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    • 2000
  • 생분해성이며 가식성 어분 단백질 필름을 가공하기 위한 기초 자료로써 명태어분 단백질 필름의 가공조건에 따른 인장강도, 신장률 및 색의 변화를 측정한 결과는 다음과 같다. 명태어분단백질 용액의 캐스팅량이 증가할수록 명태어분단백질 필름의 인장강도와 신장률은 증가하였다 반면 glycerol의 첨가량이 증가하고, 명태어분단백질 용액의 pH가 낮을수록 필름의 인장강도와 신장률은 떨어졌다. 가소제의 종류별에 따른 인장강도는 sorbitol, polyethylene glycol 및 glycerol 첨가 필름의 순으로 높게 나타났으며, 신장률은 polyethylene glycol 첨가 필름이 가장 높았고 sorbitol 및 glycerol 첨가 필름은 서로 비슷하였다. 명태어분단 백질 용액의 농도가 진할수록 필름의 인장강도도 증가하였으나, 신장률은 비슷한 경향을 나타내었다. 상대습도를 달리하여 필름을 저장한 결과 상대습도가 높을수록 인장강도는 감소하였고 신장률은 증가하였다. 가소제의 종류가 필름의 색에 미치는 효과에서 L(밝기)과 b (황객도)는 sorbitol 첨가 필름이 가장 높았고, a (적색도)와 전체적인 색의 차이 (${\delta}E$)는 polyethylene glycol 첨가 필름이 가장 높았다.

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The First Photometric Study of the Neglected Contact Binary GX Aurigae

  • Park, Jang-Ho;Lee, Jae Woo;Kim, Chun-Hwey
    • 천문학회보
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    • 제41권1호
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    • pp.41.3-42
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    • 2016
  • New CCD photometric observations of GX Aur have been made between 2004 and 2015. Our light curves are the first ever compiled and display the variable O'Connell effect. The light variations are satisfactorily modeled by including time-varying cool-spots on the component stars. Our light curve synthesis indicates that the eclipsing pair is an A-type contact binary with parameters of i = 81.1 deg, ${\Delta}T=36K$, q = 0.950 and f = 46%. Including our 25 timing measurements, a total of 83 times of minimum light spanning about 66 yr were used for a period study. It was found that the orbital period of GX Aur has varied due to two periodic oscillations superposed on an upward-opening parabolic variation. The long-term period increase rate is deduced as $+9.636{\times}10^{-10}d\;yr^{-1}$, which can be produced as a mass transfer from the secondary star to the primary at a rate of $3.136{\times}10^{-6}M_{\odot}\;yr^{-1}$, among the largest rates for contact systems. The periods and semi-amplitudes of the two periodic variations are about $P_3=8.7yr$ and $P_4=21.2yr$, and $K_3=0.011d$ and $K_4=0.017d$, respectively. The most reasonable explanation for both cycles is a pair of light-travel-time effects driven by the possible existence of an unseen third and fourth components with projected masses of $M_3=0.91M_{\odot}$ and $M_4=1.09M_{\odot}$ in eccentric orbits of $e_3=0.13$ and $e_4=0.73$. Because no third light was detected in the light curve synthesis, each circumbinary object could be a compact star or a binary itself.

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Dyeing Properties and Colour Fastness of Cotton and Silk Fabrics Dyed with Cassia tora L. Extract

  • Lee Young-Hee;Kim Han-Do
    • Fibers and Polymers
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    • 제5권4호
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    • pp.303-308
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    • 2004
  • A natural colorant was extracted from Cassia tara L. using buffer solutions (pH: 2-11) as extractants. The dyeing solution (Cassia tara L. extract) extracted using pH 9 buffer solution was found to give the highest K/S values of dyed fabrics. Cotton and silk fabrics were dyed with Cassia tara L. extract at $60^{\circ}C$ for 60 min with pre-treatment of various metal salts as mordants. It was found that Cassia tara L. extract was polygenetic dyestuffs and its major components were anthraquinones. Studies have been made on the effects of the kind of mordant on dyeing properties and colour fastnesses of cotton and silk fabrics. The K/S of cotton fabrics increased in the order of the dyeing using $FeSO_4 >CuSO_4> ZnSO_4> MnSO_4\cong Al_2(SO_4)_3 > NiSo_4 > none$, however, the K/S of silk fabrics increased in the order of the dyeing using $FeSO_4 > CuSO_4 > ZnSO_4\cong Al_2(SO_4)_3 > MnSO_4\cong NiSO_4 > none$. It was found that the K/S values of dyed fabrics were largely affected by the colour difference $(\DeltaE)$ between mordanted fabric and control fabric. However, they were not depended on the content of mordanted metal ion of the fabrics. Mordants $FeSO_4$ and CuSO_4$ for cotton fabric, $FeSO_4,\; CuSO_4,\; and\; Al_2(S0_4)_3$ for silk fabric were found to give good light fastness (rating 4).