• Title/Summary/Keyword: P analysis

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A study on the model of homebound senior's meal satisfaction related to the quality of life

  • Lee, Sun-Mee;Joo, Na-Mi
    • Nutrition Research and Practice
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    • v.6 no.4
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    • pp.357-365
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    • 2012
  • This study was conducted to develop a construct model regarding the daily activities, emotional security provided by food, enjoyment of food, level of satisfaction with delivered food, and the quality of life of homebound seniors who benefitted from meal delivery programs. The data were analyzed by SAS 9.2 and the Structural Equation Model (SEM), which was created by Analysis of Moment Structure (AMOS) 5.0 packages. The reliability of the data was confirmed by an exploratory factor analysis and through a Cronbach's alpha coefficient, and the measurement model proved to be appropriate by a confirmatory factor analysis of the measurement model in conjunction with AMOS. The results of the correlations between all the variables showed significant positive correlations (P < 0.05). The path analysis demonstrated that the daily activities (P < 0.01) and the emotional security created by food (P < 0.05) had positive correlations with the foodservice satisfaction (P < 0.05), while the daily activities (P < 0.05), the sense of emotional security made by food (P < 0.05), and food enjoyment (P < 0.05) also presented significant positive correlations with the quality of life. However, the food service satisfaction was shown to directly, but not significantly, affect the quality of life. This revealed that the current meal delivery programs needed to be improved in several directions.

p53 Mutations in Ewing's Sarcoma (유잉육종의 p53 돌연변이)

  • Bae, Dae-Kyung;Sun, Seung-Deok
    • The Journal of the Korean bone and joint tumor society
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    • v.6 no.4
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    • pp.143-151
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    • 2000
  • Purpose : The p53 tumor suppressor gene is one of the most frequently altered genes in human malignancies. We try to explore the implication of p53 alteration in Ewing's sarcoma. Materials and Methods : We analyzed 35 paraffin blocks to explore the deletion and sequence alterations of p53. Results : Quantitative PCR analysis showed that 2 tumors showed a homozygous deletion of the gene. Mutational analysis of exons 4 to 9 of p53 by PCR-SSCP revealed that 3 tumors carry sequence alterations in exons 5 or 8, and DNA sequencing analysis identified missense point mutations. Conclusion : Taken together, our data demonstrate that p53 is genetically altered in a small fraction of Ewing's sarcoma.

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A New Analysis Method of the Consolidation Test Data for an Undisturbed Clay (불교란 점토 압밀시험 결과의 새로운 해석법)

  • 박종화;고우모또타쯔야
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.44 no.6
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    • pp.106-114
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    • 2002
  • In this study, the results of a series of consolidation test for undisturbed Ariake clay in Japan were analyzed by three methods, e-log p (e: void ratio, p: consolidation pressure), log e-log p and n-log p (n: porosity). Moreover, the characteristics of each analysis method were studied. For undisturbed Ariake clay, the log o-Log p and the n-log p relationships can be found as two groups of straight lines of different gradients, but both the elastic consolidation and plastic consolidation regions of e-log p relationship are expressed as a curve. In this paper, the porosity of consolidation yield n$\_$y/, consolidation yield stress p$\_$y/, and the gradient of the plastic consolidation region C$\_$p/ were represented by the log e-log p method, and n$\_$c/, P$\_$cn/ and C$\_$cn/ were represented by the n-log p method. The meaning and the relationships of each value were studied, and the interrelationships among compression indices i.e. C$\_$cn/, C$\_$p/ and C$\_$c/ are obtained from each analysis method as a function of initial porosity n$\_$0/.

Recreational Physical Activity and Risk of Ovarian Cancer: a Meta-analysis

  • Zhou, Li-Min
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.13
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    • pp.5161-5166
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    • 2014
  • Our aim was to access the association between recreational physical activity (RPA) and risk of ovarian cancer (OC). The studies were retrieved from the PubMed and Embase databases up to February 20th, 2014. Risk ratios (OR) and 95% confidence intervals (CI) were used to estimate effect sizes. Random-effects or fixed-effects models were used to pool the data. The trim and fill method was applied for sensitivity analysis. Begg's rank correlation test and Egger's regression asymmetry test were employed to assess the publication bias. A total of 6 studies (435398 participants including 2983 OC patients) were included in this meta-analysis. The overall estimate indicated that there was weakly inverse association between RPA and OC risk (RR=0.90, 95%CI: 0.72-1.12, p=0.335). Meanwhile, for prospective cohort studies, a result consistent with the overall estimate was obtained (RR=1.12, 95% CI: 0.88-1.42, p=0.356). However, for case control studies, the pooled estimate of RR was 0.76 (95%CI: 0.64-0.90, p=0.002), indicating a clear significant association between RPA and OC risk. In addition, the sensitivity analysis indicated a significant link between RPA and risk of OC after removing Lahmann's study (RR=0.80, 95% CI: 0.68-0.93, p=0.004). No significant publication bias was found (Begg's test: p=1.00; Egger's test: p=0.817). In conclusion, our meta-analysis indicated a weakly inverse relationship between RPA and the occurrence of OC.

CPT-based p-y analysis for mono-piles in sands under static and cyclic loading conditions

  • Kim, Garam;Kyung, Doohyun;Park, Donggyu;Lee, Junhwan
    • Geomechanics and Engineering
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    • v.9 no.3
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    • pp.313-328
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    • 2015
  • In the present study, a CPT-based p-y analysis method was proposed for offshore mono-piles embedded in sands. Static and cyclic loading conditions were both taken into account for the proposed method. The continuous soil profiling capability of CPT was an important consideration for the proposed method, where detailed soil profile condition with depth can be readily incorporated into the analysis. The hyperbolic function was adopted to describe the non-linear p-y curves. For the proposed hyperbolic p-y relationship, the ultimate lateral soil resistance $p_u$ was given as a function of the cone resistance, which is directly introduced into the analysis as an input data. For cyclic loading condition, two different cyclic modification factors were considered and compared. Case examples were selected to check the validity of the proposed CPT-based method. Calculated lateral displacements and bending moments from the proposed method were in good agreement with measured results for lateral displacement and bending moment profiles. It was observed the accuracy of calculated results for the conventional approach was largely dependent on the selection of friction angle that is to be adopted into the analysis.

Relationship between Health Promotion Behavior and Marriage Value View

  • Kim, Jungae;Seo, Eunhui
    • International Journal of Advanced Culture Technology
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    • v.8 no.3
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    • pp.10-17
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    • 2020
  • This study was cross sectional descriptive survey study to analysis the relationship between marriage value view and health promotion behavior among university students. Questionnaires from those who voluntary agreed to the study were collected online, and the collection period was from May 20, 2020 to June 10, 2020. Research tools for analyzing marriage value view was used by RR lee, and health promotion behavior research tools was developed by Walker., The data analysis was performed using SPSS 18.0 as frequency, Pearson correlation, t-test, and Multiple regression analysis. According to the analysis, women had high passive (p<0.05) and exclusive (p<0.01) marriage value view, while men had high active (p<0.01) and instrumental (p<0.05) marriage value view. According to the analysis, it turns out that people who value interpersonal relationships during health promotion have a positive effect on romantic (t=2.383, R2=.257, p=.019) and instrumental (t=2.201, R2=.120, p=.030) marriage value view. Hygiene has been appeared to affect Passive marriage value view (t=3.001, R2=.111, p=.003) and Exclusive marriage value view (t=3.765, R2=.122, p=.000). Nutrition has been appeared to affect conservative marriage value view (t=2.086, R2=.118, p=0.039). Exercise has been appeared to affect conservative marriage value view (t=2.456, R2=.118, p=0.015) and active marriage value view (t=2.261, R2=.168, p=0.025). Through this study, in order to increase for the desire of marriage, marriage values need to be organized differently between men and women in marriage value programs and it suggested that health promotion behavior be included in programs that enhance the value of marriage.

The P275A Polymorphism in the Macrophage Scavenger Receptor 1 Gene and Prostate Cancer Risk: a Meta-Analysis

  • Zhou, Qiao-Xia;Tang, Jian-Qiu;Zhao, Fen;Wei, Fu-Lin;Huang, Ying
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.13
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    • pp.5407-5413
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    • 2015
  • Background: Published data regarding associations between the P275A polymorphism in the macrophage scavenger receptor 1 (MSR1) gene and prostate cancer (PCa) risk are inconclusive. The aim of this study was to comprehensively evaluate the genetic risk of P275A polymorphism in MSR1 gene for PCa. Materials and Methods: A systematic literature search was carried out in Pubmed, Medline (Ovid), Embase, CBM, CNKI, Weipu, and Wanfang databases, covering all available publications (last search was performed on Apr 27, 2015). Statistical analysis was performed using Revman 5.2 and STATA 10.1 software. Results: A total of 5,017 cases and 4,869 controls in 12 case-control studies were included in this meta-analysis. When all groups were pooled, there was no evidence that the P275A polymorphism had a significant association with PCa under dominant (OR=0.93, 95%CI=0.81-1.06, and p=0.28), co-dominant (homogeneous OR=0.97, 95%CI=0.56-1.68, and p=0.92; heterogeneous OR=0.93, 95%CI=0.74-1.15, and p=0.49), recessive (OR=1.10, 95%CI=0.65-1.87, and p=0.73), over-dominant (OR=0.93, 95%CI=0.75-1.15, and p=0.50), and allelic (OR=0.95, 95%CI=0.77-1.16, and p=0.61) genetic models. For stratified analyses by ethnicity and study design, no significant associations were found in the white race, the yellow race, the black race and mixed ethnicity, and the population-based case-control (PCC) and hospital-based case-control (HCC) studies under all genetic models. Conclusions: Based on our meta-analysis, the P275A polymorphism in the MSR1 gene is unlikely to be a risk factor for PCa.

Analysis on ISMS Certification and Organizational Characteristics based on Information Security Disclosure Data (정보보호 공시 데이터를 이용한 정보보호 관리체계 인증과 조직의 특성 분석)

  • SunJoo Kim;Tae-Sung Kim
    • Information Systems Review
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    • v.25 no.4
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    • pp.205-231
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    • 2023
  • The Information Security Management System (ISMS) is a protection procedure and process that keeps information assets confidential, flawless, and available at any time. ISMS-P in Korea and ISO/IEC 27001 overseas are the most representative ISMS certification systems. In this paper, in order to understand the relationship between ISMS certification and organizational characteristics, data were collected from Korea Internet & Security Agency (KISA), Ministry of Science and ICT, Information Security Disclosure System (ISDS), Financial Supervisory Service, Data Analysis, Retrieval and Transfer System (DART), and probit regression analysis was performed. In the probit analysis, the relationship with four independent variables was confirmed for three cases: ISMS-P acquisition, ISO/IEC 27001 acquisition, and both ISMS-P and ISO/IEC 27001 acquisition. As a result of the analysis, it was found that companies that acquired both ISMS-P and ISO/IEC 27001 had a positive correlation with the total number of employees and a negative correlation with business history. In addition, the improvement direction of the ISMS-P certification system and information security disclosure system could also be confirmed.

No Evidence of Association of the Arg72Pro p53 Gene Polymorphism with Cancer Risk in the Saudi Population: a Meta-Analysis

  • Irshad, Mohammad;Mandal, Raju Kumar;Al-Drees, Abdulmajeed;Khalil, Mahmoud Salah;Abdulghani, Hamza Mohammad
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5663-5667
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    • 2015
  • Background: Earlier studies on the association between p53 codon 72 Arg>Pro polymorphism and cancer risk were inconclusive and conflicting for the Saudi population. Therefore, we performed a meta-analysis to investigate the relationship between the codon 72 Arg>Pro polymorphism and overall cancer risk in Saudi Arabia. Materials and Methods: We searched all eligible published studies and data were pooled together to perform the meta-analysis. Pooled odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated for homozygous, heterozygous, dominant and recessive genetic models. Results: A total of five eligible published studies covering 502 cancer cases and 784 healthy controls were included in the meta-analysis. No publication bias was detected in this study. The results suggested that the variant (Pro vs Arg: p=0.960; OR=1.004, 95% CI=0.852-1.183), homozygous (Pro.Pro vs Arg.Arg: p=0.970; OR=1.006, 95% CI=0.729-1.390), heterozygous (Arg.Pro vs Arg.Arg: p=0.473; OR=0.783, 95% CI=0.402-1.527) carriers were not associated with overall cancer risk. Similarly, dominant (Pro.Pro+Pro.Arg vs Arg.Arg: p=0.632; OR=0.886, 95% CI=0.540-1.454) and recessive (Pro.Pro vs Pro.Arg+Arg.Arg: p=0.269; OR=1.163, 95%CI=0.890-1.521) models also did not indicate increased risk of cancer. Conclusions: The current meta-analysis suggests that the codon 72 Arg>Pro polymorphism of the p53 gene might not contribute to cancer susceptibility in Saudi population. Future well designed large case control studies are needed to validate our findings.

Prognostic Significance of p53 in Gastric Cancer: a Meta-Analysis

  • Yildirim, Mustafa;Kaya, Vildan;Demirpence, Ozlem;Gunduz, Seyda;Bozcuk, Hakan
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.1
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    • pp.327-332
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    • 2015
  • Background: Gastric cancer is one of the frequently seen cancers in the world and it is the second most common reason for death due to cancer. The prognostic role of expression of p53 detected by immunohistochemistry in gastric cancer remains controversial. This meta-analysis aimed to explore any association between overexpression and survival outcomes. Materials and Methods: We systematically searched for studies investigating the relationships between expression of p53 detected by immunohistochemistry and prognosis of gastric cancer patients. Study quality was assessed using the Newcastle-Ottawa Scale. After careful review, survival data were extracted from eligible studies. A meta-analysis was performed to generate combined hazard ratios for overall survival and disease-free survival. Results: A total of 4.330 patients from 21 studies were included in the analysis. Our results showed tissue p53 overexpression in patients with gastric cancer to be associated with poor prognosis in terms of overall survival (HR, 1.610; 95% CI, 1.394 -5.235; p:<0.001). Pooled hazard ratio for disease free survival showed that p53 positivity or negativity were not statitistically significant (HR, 1.219; 95%CI, 0.782-1.899; p:0.382). Conclusions: The present meta-analysis indicated overexpression of p53 detected by immunohistochemistry to be associated with a poor prognosis in patients with gastric cancer.