• Korean Journal of Environment and Ecology
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• v.33 no.3
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• pp.256-265
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• 2019

We investigated the ecological characteristics of Phoxinus phoxinus in the spring water in Eocheon stream from January to December 2016. The water temperature was $9.7{\sim}14.3^{\circ}C$ and remained below $15^{\circ}C$ throughout the year. The fishes cohabiting with minnow were Rhynchocypris kumgangensis (70.14%), Cottus koreanus (13.63%), Rhynchocypris oxycephalus (3.16%), Oncorhynchus mykiss (0.97%), Zacco koreanus (0.49%), and Iksookimia koreensis (0.24%). The sex ratio of female to male was 1:0.86. The frequency analysis of total length indicated that the fishes with the total length of 30 - 50 mm were one year old, those of 50 - 65 mm were two years old, those of 65 - 75 mm were three years old, and those of 75 mm or more were four years old. The sexually mature fishes were 50 mm or longer for female and 60 mm or longer for male. The spawning season was from April to July, and the water temperature was $12.3-14.3^{\circ}C$ during the period. The prosperous spawning season was from June to July, and the water temperature was $13.8-4.3^{\circ}C$ during the period. The average number of eggs in the ovaries was 508 per matured female, and the matured eggs were yellowish and spherical with a mean diameter of $1.58{\pm}0.13mm$. The length-weight correlation of P. phoxinus was $BW=0.000007TL^{3.09}$ with the constant a as 0.000007 and the parameter b as 3.09. The condition factor (K) was 0.99 (0.76 - 1.32) in average.

• Journal of Convergence for Information Technology
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• v.9 no.8
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• pp.140-147
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• 2019

The purpose of this study is to find biomechanical parameters for optimal shoes production through an ergonomic usability assessment of five existing types of shoes preferred by B-BOY. Ten experts and ten non-experts participated in the experiment, and 12 infrared cameras (Qualis, Oqus), force plate (Kistler, 9286AA) and foot pressure plate (Zebris Gmbh, Zebris PDM-System) were used to obtain the data. The results of the study are as follows. First, P shoes with a friction coefficient of 0.38 and a free moment of 0.32 N/m/kg are desirable in terms of traction capability and safety. Second, on the cushion, it was found that the N shoes 2.51 N, sec/kg and non-expert, and 2.86 N and sec/kg were suitable. Third, it is deemed appropriate for C shoes with a forefoot average pressure of 10.11 KPa (right), 10.05 KPa (left), and V shoes with a rearfoot average pressure of 8.4 KPa (right) and 8.36 KPa (left). In conclusion, the combination of the structure and material of V shoes should be developed for traction and stability, N shoes for cushion, and walking balance for C and V shoes.

• The Journal of the Korea Contents Association
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• v.19 no.6
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• pp.125-134
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• 2019

The purpose of this study is to explore the direction of decision support for senior citizens living alone by identifying the level of self-determination and desire for decision support. The survey was conducted on 300 elderly people living alone in five districts of Seoul. The analysis results are as follows: First, it has been shown that elderly living alone have thought that it is most important to reflect their decisions when deciding where to live. Second, respondents highly recognized that the need for support decision making as the age group grew. Third, it was found that the factors affecting the perception of the need to support decision-making by senior citizens living alone were age, trust in family and recognition of importance in decision-making. The study suggested the need for a specific, institutionalized system to support decision making for elderly living alone.

• Journal of Korean Society of Forest Science
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• v.108 no.3
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• pp.311-321
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• 2019

This study was carried out to establish basic data for the development of slow-moving landslide hazard classes. Mountain slopes in slow-moving landslide areas ranged from $11.8^{\circ}$ to $37.0^{\circ}$ with a mean slope of $23.8^{\circ}$. However, the slope inclination of microtopography in slow-moving landslide areas was slightly different, with a mean slope of $23.5^{\circ}$ ($10.7^{\circ}{\sim}41.5^{\circ}$) compared with the mountain slope. There was a significant difference (p < 0.05) between the contour intervals of microtopography and the contour intervals of the slow-moving landslide areas. Among all the slow-moving landslide areas examined, 14 plots (approximately 38.0%) were classified into landslide hazard class I, 6 plots (approximately 16.0%) into landslide hazard class II, 5 plots (approximately 14.0%) into landslide hazard class III and IV, and 16 plots (approximately 43.0%) into landslide hazard class V, whereas 9 plots (approximately 24.0%) fit the no landslide hazard class.

• Journal of Physiology & Pathology in Korean Medicine
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• v.33 no.3
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• pp.175-180
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• 2019

Torilis Japonica (TJ) has been used as an anti-allergy, antifungal, and antibacterial agent. Recent studies have reported that it also shows anti-cancer effects. It is report that TJ inhibits melanin synthesis in melanocyte in the skin. However, the effect and mechanism of TJ extract (TJE) on Ultraviolet (UV)B-induced photoaging are unknown. In this study, we investigated the preventive effects of TJE on matrix metalloproteinase (MMP)-1 and MMP-3 expressions and the underlying molecular mechanism in UVB-irradiated primary human dermal fibroblasts (HDFs). The effect of TJE on HDF cell viability was determined using the XTT assay and cell counting. MMP-1 and MMP-3 expressions levels were measured by western blotting and real-time PCR analysis. Activations of mitogen-activated protein kinase (MAPKinase), nuclear $factor-{\kappa}B$ ($NF-{\kappa}B$), and activator protein-1(AP-1) were measured by western blotting. Our results showed that TJE effectively reduced UVB-induced MMP-1 and MMP-3 protein and mRNA levels. Moreover, TJE significantly blocked the UVB-induced activation of MAPK (p38 and JNK) and transcription factors ($NF-{\kappa}B$ and AP-1), but not ERK. Taken together, our results suggest that the TJE inhibits UVB-induced MMP expressions in HDFs and its may be a potential agent for the prevention and treatment of skin photoaging.

• Clinical and Experimental Pediatrics
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• v.61 no.12
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• pp.403-406
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• 2018

Floating-Harbor syndrome is a rare autosomal dominant genetic disorder associated with SRCAP mutation. To date, approximately 50 cases of Floating-Harbor syndrome have been reported, but none have been reported in Korea yet. Floating-Harbor syndrome is characterized by delayed bony maturation, unique facial features, and language impairment. Here, we present a 6-year-old boy with a triangular face, deep-set protruding eyes, low-set ears, wide nose with narrow nasal bridge, short philtrum, long thin lips, clinodactyly, and developmental delay that was transferred to our pediatric clinic for genetic evaluation. He showed progressive delay in the area of language and cognition-adaption as he grew. He had previously undergone chromosomal analysis at another hospital due to his language delay, but his karyotype was normal. We performed targeted exome sequencing, considering several syndromes with similar phenotypes. Library preparation was performed with the TruSight One sequencing panel, which enriches the sample for about 4,800 genes of clinical relevance. Massively parallel sequencing was conducted with NextSeq. An identified variant was confirmed by Sanger sequencing of the patient and his parents. Finally, the patient was confirmed as the first Korean case of Floating-Harbor syndrome with a novel SRCAP (Snf2 related CREBBP activator protein) mutation (c.7732dupT, p.Ser2578Phefs*6), resulting in early termination of the protein; it was not found in either of his healthy parents or a control population. To our knowledge, this is the first study to describe a boy with Floating-Harbor syndrome with a novel SRCAP mutation diagnosed by targeted exome sequencing in Korea.

• Microbiology and Biotechnology Letters
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• v.47 no.3
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• pp.390-400
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• 2019

In this study, strains isolated from soil samples collected from Busan, Changwon, and Jeju Island were examined to verify their abilities of phosphate solubilization and nitrogen fixation, production of indole-3-acetic acid (IAA), siderophore, and 1-aminocylopropane-1-carboxylyic acid (ACC) deaminase in order to select strains that promote plant growth and play a role in biocontrol of pests or pathogens. According to the results of this study, most of the isolated strains were found to have ability of phosphate solubilization, nitrogen fixation, IAA production, siderophore production, and production of ACC deaminase. These isolated strains might help plant growth by directly improving absorption of nutrients essential for phosphate solubilization and nitrogen fixation. In addition, they can promote plant growth and control resistance to plant diseases through extracellular enzyme activity and antifungal activity. In addition, most of the selected strains were found to survive in various environmental conditions such as temperature, salinity, and pH. Therefore, Pseudomonas plecoglossicida ANG14, Pseudarthrobacter equi ANG28, Beijerinckia fluminensis ANG34, and Acinetobacter calcoaceticus ANG35 were finally selected through a comparative advantage analysis to suggest their potential as novel biological agents. Further studies are necessary in order to prove their efficacy as novel biological agents through formulation and optimization of effective microorganisms, their preservation period, and crop cultivation tests.

• Journal of Korean Society of Forest Science
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• v.108 no.3
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• pp.329-340
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• 2019

Water pollution in erosion control dams is a major issue for forest watershed management, but the effects of erosion control dams on water quality remain poorly understood. In this study, water quality data from streams and dam reservoirs were collected over the Nakdong river basin. Monitored data were further analyzed to examine the relationship between watershed characteristics and water quality. Of the total 43 erosion control dams, less than 10% had lower water quality that was not suitable for agricultural use. TOC and oxygen demand, SS and turbidity, SS and Chl-a, and Chl-a and turbidity showed high correlations (p < 0.01) both in stream water and in detained water. BOD and SS, BOD and Chl-a, BOD and turbidity, and TOC and Chl-a showed high correlations only in stream water. Overall, the results demonstrated that for most erosion control dams the water quality was relatively good. In addition, the quality of downstream water is somewhat affected by the water detained by erosion control dams, in limited ways.

• The Journal of the Convergence on Culture Technology
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• v.5 no.3
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• pp.229-239
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• 2019

Rapid economic development has changed the dietary habits and patterns. Especially, western style diet has increased the risk of type 2 diabetes (T2DM) in Korea. To provide more specific and appropriate diet guideline for the prevention and for the treatment of T2DM, the investigation on the characteristics of diebetic patients related to the diet needs to be done. In this study, we therefore analyzed eating behaviors, dietary attitudes, and intake of food and nutrients of normal subjects (control, n=26) and diabetic patients (case, n=18) diagnosed T2DM within one year in Daegu Gyeongbuk area. Body mass index of the patients were significantly higher than the control (p<0.05). Overeating, high fried food and low whole grain intake were revealed as risk factors for T2DM. From the food frequency questionnaire analysis, salty foods such as fermented soybean paste (Doenjang) and watery Kimch intake were associated with T2DM. Intake of vegetable lipid, ${\beta}$-carotene, calcium, copper, and vitamin K were also shown to be associated with T2DM. Taken together, these findings suggest that maintaining ideal body weight and intake the foods with low salt, fat, and refined grain in appropriate amount may help to prevent and to manage T2DM.

• Biomedical Science Letters
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• v.25 no.3
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• pp.218-226
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• 2019

In old age, measures to cope with the natural phenomenon of aging and various diseases of the elderly due to the deterioration of physical function are also a challenge for this society. While interest in systematic health is increasing, it is true that awareness and interest in oral-related diseases is relatively lacking. This study aims to present basic data necessary to improve the quality of life for senior citizens aged 65 or older by improving the oral dryness caused by systemic health. By research method, improve oral dryness caused by whole-body health with the elderly over 65 and promote their oral health, inducing the increase of the salivary flow rate through oral health care education, oral exercise, and salivary gland massage. First, on the DMSQ according to the general characteristics of the elderly, the recognition of the whole body and oral health status, independent sample t-test and One-way ANOVA were conducted. Second, on changes in the salivary flow rate and saliva pH according to the general characteristics of the elderly, recognition of oral and whole-body health status, and whole-body health, paired samples t-test was conducted. Studies have shown that salivary gland flow increased significantly after oral exercise and salivary gland massage, the salivary flow rate significantly increased. In all variables of the recognition of the oral health status, the salivary flow rate increased after oral exercise and salivary gland massage, and in the whole-body health, regardless of hypertension, diabetes, cardiovascular disorders, and osteoporosis, the salivary flow rate increased after oral exercise and salivary gland massage, and the salivary flow rate increased after oral exercise and salivary gland massage if the subjects responded that they did not have thyroid abnormality, anemia, abnormalities of breathing, hypotension, gastrointestinal disturbance, or kidney diseases. As a comprehensive analysis of this study, many felt oral dryness when they had a problem with the whole-body health, and many felt oral dryness when they had a problem with oral health cognition. After applying oral exercise and salivary gland massage as intervention methods in the oral health care for the elderly, the salivary flow rate significantly increased, and it is judged that the methods were very effective for controlling oral dryness. Furthermore, it is judged that the factors affecting oral health, whole-body health, and oral dryness would be identified, which would be helpful for the promotion of whole-body health and oral health. It is judged that continuous research would be needed so that measures for the application of the oral care program and system for the elderly would be prepared in the future.