• KSBB Journal
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• 제26권4호
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• pp.311-316
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• 2011

We investigated the optimal surface aeration rate during bioethanol production from the hydrolysate of seaweed Sargassum sagamianum using Pichia stipitis. It was observed that, when the working volume was 880 mL in 2.5-L lab-fermentor, the surface aeration rates of 30 to 100 mL/min were the optimal values for bioethanol production, in which this surface aeration rate corresponded to less than 0.05 (1/min) as the oxygen transfer rate coefficient ($k_La$). In addition, during repeated-batch operation was carried out, we examined whether those surface aeration rates were the optimal for bioethanol production. It was also observed that the surface aeration rates of 30 to 100 mL/min in the working volume of 880 mL were the optimal values in terms of the cumulative bioethanol producrion and bioethanol yield. On the basis of the oxygen transfer rate coefficient it is probable that those surface aeration rates will be applied to the large-scale bioethanol production from the hydrolysate of seaweed Sargassum sagamianum.

• Biotechnology and Bioprocess Engineering:BBE
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• 제11권3호
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• pp.245-250
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• 2006

The effects of aliphatic hydrocarbons (n-hexadecane and n-dodecane) on the volumetric oxygen mass transfer coefficient $(k_L\;a)$ were studied in flat alveolar airlift reactor and continuous stirred tank reactors (CSTRs). In the flat alveolar airlift reactor, high aeration rates (>2vvm) were required in order to obtain efficient organic-aqueous phase dispersion and reliable $k_La$ measurements. Addition of 1% (v/v) n-hexadecane or n-dodecane increased the $k_La$ 1.55- and 1.33-fold, respectively, compared to the control (superficial velocity: $25.8{\times}10^{-3}m/s$, sparger orifice diameter: 0.5 mm). Analysis of the gas-liquid interfacial area a and the liquid film mass transfer coefficient $k_L$ suggests that the observed $k_La$ increase was a function of the media's liquid film mass transfer. Addition of 1% (v/v) n-hexadecane or n-dodecane to analogous setups using CSTRs led to a $k_La$ increase by a factor of 1.68 and 1.36, respectively (superficial velocity: $2.1{\times}10^{-3}m/s$, stirring rate: 250 rpm). These results propose that low-concentration addition of oxygen-vectors to aerobic microbial cultures has additional benefit relative to incubation in purely aqueous media.

• 한국항공우주학회지
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• 제36권3호
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• pp.264-270
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• 2008

하이브리드 로켓 고체 연료의 연소율(Burning Rate)을 묘사하는 후퇴율은 연료 유속, 산화제 유속과 더불어 연료길이의 함수로 나타내어지나 일반적으로 가장 영향이 큰 산화제 유속만의 함수로 모델링된다. 그러나 이는 연료가 갖고 있는 고유의 열화학적 특성에 대한 영향이 내포되어 있지 않아 다양한 연료에 대한 공통된 관계를 나타내기 어렵다. 본 연구에서는 고체연료의 열화학적 특성과 연소에 따른 공기역학적 특성이 고려된 물질전달수(B Number)를 도입하여 다양한 연료에 공통으로 사용될 수 있는 연소율 관계식을 제시하고, 물질전달수 내의 공기역학적 특성의 영향을 분석하였다. 물질전달수와 산화제 유속의 함수로 표현된 연소율 식은 고정된 실험 지수항과 상수항으로 PMMA, PP 및 PE의 연소율을 모두 묘사할 수 있었고, 연소율 관계식에서 B Number에 내포된 공기역학적 효과는 미미하였다.

• 대한의용생체공학회:의공학회지
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• 제28권3호
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• pp.387-391
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• 2007

An oxygenator is a very important artificial organ and widely used for patients with lung failure or during open heart surgery. Although an oxygenator has been widely studied worldwide to enhance its efficiency, studies on oxygenators, in particular when using a pulsatile blood flow, are domestically limited. Therefore, a new oxygenator was developed in the lab and animal experimental results are described in the paper. The oxygenator is composed of polycarbonate housing and polypropylene hollow fibers. It has a total length of 400 mm and a surface area of $1.7 m^2$. The animal experiment lasted for 4 hours. The blood flow rate was set to 2 L/min and a pulsatile blood pump, T-PLS (Twin-Pulse Life Support), was used. Samples were drawn at the oxygenator's inlet and outlet. The total hemoglobin (Hb), saturation oxygen ($sO_2$), and partial oxygen pressure ($pO_2$), partial $CO_2$ pressure ($pCO_2$), and plasma bicarbonate ion concentration ($HCO_3^-$) were measured. The oxygen and carbon dioxide transfer rates were also calculated based on the experimental data in order to estimate the oxygenator's gas transfer efficiency. The oxygen and carbon dioxide transfer rates were $16.4{\pm}1.58$ and $165.7{\pm}10.96 mL/min$, respectively. The results showed a higher carbon dioxide transfer rate was achieved with the oxygenator. Also, the mean inlet and outlet blood pressures were 162.79 and 137.92 mmHg, respectively. The oxygenator has a low pressure drop between its inlet and outlet. The aim of own preliminary study was to make a new oxygenator and review its performance when applying a pulsatile blood pump thus, confirming the possibility of a new oxygenator suitable for pulsatile flow.

• Computers and Concrete
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• 제12권5호
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• pp.669-680
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• 2013

This paper unveils a new computer based stabilization methodology for automated modeling analysis and its experimental verification for corrosion in reinforced concrete structures under the effect of varying oxygen concentration. Various corrosion cells with different concrete compositions under four different environmental conditions (air dry, submerged, 95% R.H and alternate wetting-drying) have been investigated under controlled laboratory conditions. The results of these laboratory tests were utilized with an automated computer-aided simulation model. This model based on mass and energy stabilization through the porous media for the corrosion process was coupled with modified stabilization methodology. By this coupling, it was possible to predict, maintain and transfer the influence of oxygen concentration on the corrosion rate of the reinforcement in concrete under various defined conditions satisfactorily. The variation in oxygen concentration available for corrosion reaction has been taken into account simulating the actual field conditions such as by varying concrete cover depth, relative humidity, water-cement ratio etc. The modeling task has been incorporated by the use of a computer based durability model as a finite element computational approach for stabilizing the effect of oxygen on corrosion of reinforced concrete structures.

• Clinical and Experimental Reproductive Medicine
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• 제46권4호
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• pp.189-196
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• 2019

Objective: We aimed to evaluate the effects of different oxygen conditions (20% [high O₂], 5% [low O₂] and 5% decreased to 2% [dynamic O₂]) on mouse pre- and peri-implantation development using a novel double-channel gas supply (DCGS) incubator (CNC Biotech Inc.) to alter the oxygen concentration during in vitro culture. Methods: The high-O₂ and low-O₂ groups were cultured from the one-cell to the blastocyst stage under 20% and 5% oxygen concentrations, respectively. In the dynamic-O₂ group, mouse embryos were cultured from the one-cell to the morula stage under 5% O₂ for 3 days, followed by culture under 2% O₂ to the blastocyst stage. To evaluate peri-implantation development, the blastocysts from the three groups were individually transferred to a fibronectin-coated dish and cultured to the outgrowth stage in droplets. Results: The blastocyst formation rate was significantly higher in the low-O₂ and dynamic-O₂ groups than in the high-O₂ group. The total cell number was significantly higher in the dynamic-O₂ group than in the low-O₂ and high-O₂ groups. Additionally, the apoptotic index was significantly lower in the low-O₂ and dynamic-O₂ groups than in the high-O₂ group. The trophoblast outgrowth rate and spread area were significantly higher in the low-O₂ and dynamic-O₂ groups than in the high-O₂ group. Conclusion: Our results showed that a dynamic oxygen concentration (decreasing from 5% to 2%) had beneficial effects on mouse pre- and peri-implantation development. Optimized, dynamic changing of oxygen concentrations using the novel DCGS incubator could improve the developmental competence of in vitro cultured embryos in a human in vitro fertilization and embryo transfer program.

• 한국화재소방학회논문지
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• 제30권6호
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• pp.78-83
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• 2016

발사체의 지상 운영과정이나 발사과정에서 일어날 수 있는 화재와 폭발사고 예방을 위해 1단 동체 내부에 형성될 수 있는 연소 환경에서 화염의 전파특성을 고찰해 보았다. 이를 위해 1단 동체 내부에 형성될 수 있는 고산소-저기압 환경을 연소챔버 내에 조성하고 고체연료를 점화시켜 화염 전파율을 측정하였다. 고체연료로는 두께가 0.18 mm인 광섬유를 사용하였다. 주어진 조건에서 산소농도가 증가함에 따라 광섬유를 따라 전파하는 화염의 속도는 급격히 증가하였지만 챔버 내의 압력이 대기압에 가까질 수록 화염의 전파속도는 감소하였다. 압력 증가에 따른 화염전파율의 감소의 원인을 파악하기 위해 대류열전달계수와 화염전파율의 압력 상관성 분석해 보았으며, 이를 통해 압력이 낮아질수록 대류 열손실이 줄어들어 화염전파율이 증가하는 것을 확인하였다.

• 한국수소및신에너지학회논문집
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• 제16권3호
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• pp.209-218
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• 2005

To find a suitable metal component in oxygen carrier particles for chemical-looping hydrogen generation system(CLH), oxygen transfer capacities of metal components were compared and Ni has been selected as the best metal component. The proper operating conditions to achieve high hydrogen generation rate have been investigated based on the chemical-equilibrium composition analysis for water splitting reactor. Moreover, suitable compositions of syngas from gasifier of heavy residue to achieve high energy efficiency have been investigated by calculation of heat of reaction. Based on the selected operating conditions, the best configuration of two interconnected fluidized beds system for the chemical-looping hydrogen generator has been investigated as well.

• 한국미생물·생명공학회지
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• 제35권3호
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• pp.226-230
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• 2007

산소를 많이 소비하는 발효공정일수록 배양액중의 용존산소의 농도가 목적생산물의 생산성에 많은 영향을 주는 경우가 많다. 때문에 고농도 발효에 앞서, 발효조의 sparging hole로부터 임펠러 높이에 따른 산소전달 능력을 알아본 결과 공기공급이 1 vvm, 교반속도가 600 rpm에서 산소전달계수($K_La$)는 2.67($min^{-1}$)으로 가장 높았다. 배양 시 용존산소 농도를 20% 이상 유지시켰을 때 온도에 따른 k6ub/IFN-${\alpha}1$ 생성은 $30^{\circ}C$에서 세포증식을 하고 $25^{\circ}C$에서 IPTG로 Induction 하였을 때 발현율이 6.43mg/ml로 total protein의 37%로 가장 많은 양이 발현되는 것을 알 수 있었다. 용존산소 농도에 따른 k6ub/IFN-${\alpha}1$의 발현양은 용존산소 농도가 35%일 때 가장 높은 수율을 나타냈다. 용존산소량은 산소소비 속도를 측정함으로써 정확한 임계점을 찾을 수 있었는데 용존산소량이 35% 유지될 때 산소 전달 속도와 비교하여 가장 적당한 산소공급량임을 확인할 수 있었다.

• 한국화재소방학회논문지
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• 제28권5호
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• pp.1-7
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• 2014

본 연구에서는 대형 콘 칼로리미터(large scale cone calorimeter, LSC)를 사용하여 헵탄 풀 화재(pool fire) 실험에서 화원의 직경 변화에 따른 발열량(HRR) 측정 결과를 정량적으로 분석하였다. 발열량에 중요한 영향을 미치는 연소율(burning rate)은 A. Hamins의 연구 자료에서 제시한 모델링 곡선과 비교하여 정확성을 검증하였으며, 산소 소모법에 의한 연소효율(combustion efficiency)은 이론발열량에 비해서 91% 정도로 J. Gore이 제시한 헵탄의 연소효율 92%와 유사한 것을 확인하였다. 엔탈피소모법에 의한 열손실은 전체 발열량의 54% 정도로 측정부에서 대류 발열량으로 측정되었으며, 본 연구 결과는 화재실험에서 발열량 측정값의 신뢰성 분석(reliability analysis)을 위한 기초 연구 자료로 활용하는데 유용한 정보가 될 것으로 사료된다.