• 제목/요약/키워드: Outcomes analysis

검색결과 3,530건 처리시간 0.028초

The Effect of Locally Administered Fibrinolytic Drugs Following Aneurysmal Subarachnoid Hemorrhage : A Meta-Analysis with Eight Randomized Controlled Studies

  • Jang, Kyoung Min;Choi, Hyun Ho;Nam, Taek Kyun;Park, Yong Sook;Kwon, Jeong Taik;Byun, Jun Soo;Hwang, Doyeon
    • Journal of Korean Neurosurgical Society
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    • 제64권2호
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    • pp.207-216
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    • 2021
  • Objective : Rapid dissolution of blood clots reduces vasospasm and hydrocephalus after subarachnoid hemorrhage (SAH), and locally administered fibrinolytic drugs (LAFDs) could facilitate the dissolution. However, the efficacy of LAFDs remains controversial. The aim of this meta-analysis was to determine the efficacy of LAFDs for vasospasm and hydrocephalus and in clinical outcomes. Methods : From PubMed, EMBASE, and Cochrane database, data were extracted by two authors. Meta-analysis was performed using a random effect model. Inclusion criteria were patients who had LAFDs with urokinase-type or recombinant tissue-plasminogen activator after SAH in comparison with medically untreated patients with fibrinolytic drugs. We only included randomized controlled trials (RCTs) in this analysis. The outcomes of interest were vasospasm, hydrocephalus, mortality, and 90-day unfavorable functional outcome. Results : Data from eight RCTs with 550 patients were included. Pooled-analysis revealed that the LAFDs were significantly associated with lower rates of vasospasm (LAFDs group vs. control group, 26.5% vs. 39.2%; odds ratio [OR], 0.48; 95% confidence interval [CI], 0.32-0.73); hydrocephalus (LAFDs group vs. control group, 26.0% vs. 31.6%; OR, 0.54; 95% CI, 0.32-0.91); and mortality (LAFDs group vs. control group, 10.5% vs. 15.7%; OR, 0.58; 95% CI, 0.34-0.99). The proportion of 90-day unfavorable outcomes was lower in the LAFDs group (LAFDs group vs. control group, 32.7% vs. 43.5%; OR, 0.55; 95% CI, 0.37-0.80). Conclusion : This meta-analysis with eight RCTs indicated that LAFDs were significantly associated with lower rates of vasospasm and hydrocephalus after SAH. Thus, LAFDs could consequently reduce mortality and improve clinical outcome after SAH.

Maternal and fetal outcomes of pregnancies in kidney donors: A 30-year comparative analysis of matched non-donors in a single center

  • Yoo, Kyung Don;Lee, Hajeong;Kim, Yaerim;Park, Sehoon;Park, Joong Shin;Hong, Joon Seok;Jeong, Chang Wook;Kim, Hyeon Hoe;Lee, Jung Pyo;Kim, Dong Ki;Oh, Kook-Hwan;Joo, Kwon Wook;Kim, Yon Su
    • Kidney Research and Clinical Practice
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    • 제37권4호
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    • pp.356-365
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    • 2018
  • Background: Woman kidney donors face obstetric complication risks after kidney donation, such as gestational hypertension and preeclampsia. Studies on childbirth-related complications among Asian women donors are scarce. Methods: This retrospective cohort study included woman donors aged 45 years or younger at the time of kidney donation in a single tertiary hospital between 1985 and 2014. Pregnancy associated complications were investigated using medical records and telephone questionnaires for 426 pregnancies among 225 donors. Matched non-donor controls were selected by propensity score and the maternal and fetal outcomes were compared with those of donors. Primary outcomes were differences in maternal complications, and secondary outcomes were fetal outcomes in pregnancies of the donor and control groups. Results: A total of 56 cases had post-donation pregnancies. The post-donation pregnancies group was younger at the time of donation and older at the time of delivery than the pre-donation pregnancies group, and there were no differences in primary outcomes between the groups except the proportion receiving cesarean section. Comparison of the complication risk between post-donation pregnancies and non-donor matched controls showed no significant differences in gestational hypertension, preeclampsia, or composite outcomes after propensity score matching including age at delivery, era at pregnancy, systolic blood pressure, body weight, and estimated glomerular filtration ratio (odds ratio, 0.63; 95% confidence interval, 0.19-2.14; P = 0.724). Conclusion: This study revealed that maternal and fetal outcomes between woman kidney donors and non-donor matched controls were comparable. Studies with general population pregnancy controls are warranted to compare pregnancy outcomes for donors.

불면환자에 대한 수기치료 효과의 임상 사례 보고 (The Clinical study of Su-Gi therapy's Effects on Insomnia by observing of ISI and PSQI)

  • 김민석;안훈모;김준철
    • 대한의료기공학회지
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    • 제15권1호
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    • pp.61-70
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    • 2015
  • Objectives : The purpose of this study is to investigate the effects of Su-Gi therapy for Insomnia by using ISI scores and PSQI test. Methods : We investigated 4 patients on condition of Insomnia who was hospitalized in the M Korean medicine hospital in Gyeonggi Province from 8th June, 2015 to 21st October, 2015. The Su-Gi therapy was treated on patients once a day for 10 minutes. We figured out the outcome by using ISI scores and PSQI test. Results : There were no differences on average sleeping time and the time to falling a sleep. Meaningful outcomes in values of ISI scores and PSQI test was not deduced after Su-Gi therapy. There were some progress on disturbance of daytime due to insomnia, ISI scores and PSQI test. In the Correlation analysis of outcomes of before and after the Su-Gi therapy, there were some improvements on ISI scores and PSQI tests and some questionnaire but were not enough to reach meaningful outcomes. We concluded that the more treatment time is needed to improve the condition of patients on insomnia as we see in PSQI test, one month is minimum period time to draw the conclusion. Conclusions : Theses outcomes suggest a possibilities that improvements who are suffering from insomnia can be get well when the Su-Gi therapy is performed for sufficient moments.

액션러닝 기반 간호관리학 강의 및 실습 운영의 효과 (Effects of Action Learning Approaches on Learning Outcomes in Nursing Management Courses)

  • 장금성;박순주
    • 간호행정학회지
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    • 제18권4호
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    • pp.442-451
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    • 2012
  • Purpose: The purpose of this study was to identify effects of action learning approaches on learning outcomes of students taking nursing management courses. Methods: The questionnaire surveys were completed between March 2011 and June 2012 by 109 undergraduate seniors in the nursing department of C University. Survey data were obtained 3 times: before, in and after the study of nursing management. The course consisted of lectures and clinical practices. Learning outcomes were measured through problem solving skills, team efficacy, and class satisfaction. Collected data were analyzed using repeated measures ANOVA with the SPSS 20.0 program Results: Scores for problem solving skills (F=13.67, p<.001) and team efficacy (F=4.49, p=.012) showed statistically significant increases after the course. The scores also increased significantly after the lectures for 5 of 9 problem solving skill subscales: analysis skill, divergent thinking, decision making, assessment, feedback, and after the clinical practices for 2 subscales: divergent thinking, and execution and risk taking. Class satisfaction score also increased after both the lectures and the clinical practices. Conclusion: The findings from this study suggest that an action learning approaches for nursing management courses would be a useful teaching and learning method to achieve learning outcomes.

정보기술 이전의 개념적 문화모형 (The Conceptual Cultural Model of Information Technology Transfer)

  • Kang, Byung-Goo
    • 정보기술응용연구
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    • 제1권
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    • pp.153-170
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    • 1999
  • Business organizations suffer from transferring information technology(IT) into practice. If the problem is solely an technical issue, the strategy to solve the problem is assumed to be identical regardless of the cultural differences of the organizations. Many studies, however, indicated that the cultural differences between organizations were attributed to the differences of championing behaviors in the organizations. The study develops the cultural model of IT transfer from well developed countries to the less developed countries. It is assumed that the outcomes of IT systems are affected by the cultural sets, technology acculturation, and national technology infrastructure. This study examines the effects of cultural sets and technology acculturation on the outcome of IT systems, however. The analysis results show that technological acculturation has strong relationship with the individual IT outcomes and the cultural sets. The cultural sets, however, did not show any significant relation with the individual IT outcomes in the context of the structural model even though the correlation between the cultural sets and the IT outcomes were relatively high. Thus, kit is considered that the interaction between the technological acculturation and the cultural sets might interfere the relations.

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사무공간내의 공간통제, 공간융통성 및 산만함이 업무에 미치는 영향 (Interrelated effects of control, flexibility and distraction on work outcomes)

  • 이소영
    • 한국실내디자인학회논문집
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    • 제14권2호
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    • pp.135-141
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    • 2005
  • Subsequent to major changes in workplace such as communication method, uncertain organizational environment, and globalizaiton, several studies in workplace have explored the effects of those changes on work outcomes. Especially, employees need to have the balance in working alone and working with others. The purpose of this study is to examine the effects of control over the physical environment by individuals and the effects of flexibility on individual and group work outcomes in the workplace, to examine the effects of distraction on work outcomes, and to suggest a interrelationships among variables. In this study, four hundred and nine questionnaires were collected from employees of three manufacturing corporations in Michigan, U. S. In order to explore the causal interferences among multiple relationships suggested in this study, path analysis was employed using Lisrel 8.54. The results indicated that control over the physical environmental features of the workplace positively influenced job satisfaction. The findings also supported the hypothesis that flexibility is positively related to task group cohesiveness. It was found that distraction was negatively associated with control and flexibility. However, it was not supported that control was positively associated with perceived performance. This study found control and flexibility in the workplace to be important. Some practical implications were suggested emphasizing that control and flexibility allow limited resources to be used in ways that permit individuals to work effectively within a changing work environment.

노인의 규칙적 신체활동이 심혈관 기능에 미치는 영향 고찰 (Relationship between Physical activity and Cardiovascular Outcomes in the Korean Elderly: Review of Experimental Studies)

  • 채영란;김증임;임경춘
    • 여성건강간호학회지
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    • 제20권4호
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    • pp.309-317
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    • 2014
  • Purpose: The purpose of this study was to review the relationship between physical activity and cardiovascular outcomes in the Korean elderly. Methods: Experimental studies were located using PubMed, CINAHL, PsycINFO, Cochrane, RISS, KISS, and KoreaMed. The selected studies for analysis were 20 articles of cardiovascular outcomes (total cholesterol, triglyceride, high density lipoprotein (HDL), low density lipoprotein (LDL), blood pressure, and pulse rate) from 515 articles. Results: One-group pretest-posttest design was the most common. The main physical activity was an aerobic exercise. Five of 14 studies reported a significant improvement of total cholesterol. Four of 14 studies found relationship between exercise and triglyceride. Eight of 12 studies reported a significant improvement of HDL, whereas 3 of 9 studies reported a significant improvement of LDL. In over 60% of selected studies, reported significant improvement of blood pressure. Conclusion: Based on the review, it suggests that regular physical activity of the elderly may improve cardiovascular outcomes.

지역거주 노인의 근골격계 기능향상 신체활동에 관한 문헌 고찰연구 (Literature Review for the Effects of Physical Activity on Musculoskeletal Outcomes in Community-Dwelling Older Adults)

  • 임경춘;김증임;채영란
    • 여성건강간호학회지
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    • 제20권4호
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    • pp.297-308
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    • 2014
  • Purpose: The purpose of this study was to review the effects of physical activity on musculoskeletal outcomes in older Koreans. Methods: Experimental studies were retrieved from the search engines (PubMed, CINAHL, PsycINFO, Cochrane, RISS, KISS, and KoreaMed). The selected studies for analysis were 27 articles of musculoskeletal outcomes (gait, muscle strength, flexibility, balance, grip strength, endurance, body fat, and weight) from 515 articles. Results: The most common type of physical activity was a resistance exercise. There were significant improvements in gait (71.4%), muscle strength (86.7%), flexibility (63.6%), balance (72.2%), grip strength (71.4%), endurance (71.4%), body fat (57.1%), and weight (28.6%). The activity programs that apply over 150 minutes a week showed greater improvement of 69.5% than 65.0% from those did not meet the guidelines totally. Conclusion: Based on the review, we conclude that regular physical activity in the elderly may improve the musculoskeletal outcomes. To be more effective programs, it is necessary to meet the guidelines of 150 minutes a week or 30 minutes of moderate-intensity activities on 5 days per week for the elderly.

The Bright and Dark Side of Pre-existing Social Ties and Relational Orientation in Research Collaborations in South Korea

  • HEMMMERT, Martin;KIM, Jae-Jin
    • The Journal of Asian Finance, Economics and Business
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    • 제7권1호
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    • pp.279-290
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    • 2020
  • Informal networks between individuals are widely seen as important in East Asian business systems. However, while the performance implications of guanxi in China have been extensively studied, much less is known on how informal networks may influence business outcomes in other East Asian countries. We examine informal networks in inter-organizational research collaborations in South Korea by studying the role of pre-existing social ties and relational orientation in new product development (NPD) collaborations and university-industry research (UIR) collaborations. We conduct an interview-based, in-depth case analysis of five NPD collaborations and five UIR collaborations. Pre-existing social ties and relational orientation are prevalent in both types of research collaborations. However, they have different consequences for collaboration outcomes. Pre-existing social ties strongly vary in their types and strength, and negatively affect collaboration outcomes unless they result in the selection of competent and motivated partners. Relational orientation manifests itself in a task-related and social exchange between collaboration partners, which contributes to outcomes such as knowledge acquisition and business performance. Korean collaboration managers should rely only on pre-existing social ties that are well-aligned with task-related requirements when initiating and conducting research collaborations. However, the creation of strong relationships between collaboration team members of partnering organizations should be encouraged.

영국 철도 민영화에 있어 철도안전의 성과와 과제 (The Outcomes and Tasks of UK Rail Privatization in case of Safety)

  • 이용상
    • 한국철도학회논문집
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    • 제9권2호
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    • pp.212-221
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    • 2006
  • This paper examines the outcomes and tasks of U rail privatization especially focusing on the rail safety. Earlier research which focused on the rail safety had little knowledge of the explanations for recent changes of safety scheme. Moreover, they had difficulty making a direct comparison of safety between national rail and the privatized rail. Therefore we are left without a good explanation which has a comprehensive perspective. I attempt to show the outcomes of safety in the rail privatization process and its tasks focusing on the recent fatal accident. This paper argues that the UK's rail safety has a framework which is too complicated with overlapping responsibilities that brought about inefficiency, increasing costs. Especially infrastructure enterprise did not come to play an appropriate role. However, after 2000, the government took charge of setting the strategy for railway safety, and the Office of Rail Regulation covered safety, performance and cost. I explain that these changes present a good opportunity to solve the problem of passing the buck for rail accident. Through the analysis, I find that outcomes of rail privatization in safety are improved comparing the national rail. However, safety performance, for example the collision of structures of cars and looseness of rail should be improved. In future, the problems of fatal accident and a bit of duplicate safe system should be addressed.