• Korean Journal of Food Science and Technology
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• v.40 no.1
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• pp.36-41
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• 2008

This study was conducted to investigate the effects of combined osmotic dehydration and hot-air drying on the quality of dried apple products. Apple cylinders were steeped in 30% and 50% sucrose solutions at different steeping times. During the osmotic dehydration, as the concentration of the sucrose solution and steeping time increased, weight reduction and water loss increased, and the solid gain showed similar results. Osmotic dehydration in the sucrose solutions was followed by hot-air drying at 50 and $70^{\circ}C$. The experimental data were fitted successfully using the modified Page model. At the drying temperature of $50^{\circ}C$, the drying time increased from 4.15 hr for the control to 5.78 hr and 6.42 hr for the 30 and 50% sucrose solution treatments, respectively. Similar results were shown at the $70^{\circ}C$ drying temperature. The k and n values of the apple cylinders decreased by osmotic dehydration, and the k and n of the apple cylinders steeped in the 50% sucrose solution were lower than those of the samples steeped in the 30% sucrose solution. The qualities of the dried apple products were compared to samples that did not undergo osmotic dehydration. The shrinkage and rehydration capacity of the apple products decreased via osmotic dehydration, and decreased as the concentration of the sucrose solution increased. The compressibility ratios of the apple products to raw apple cylinders increased by osmotic dehydration, and increased as the concentration of sucrose solution increased. The sensory evaluation results for the apple products rehydrated in yoghurt indicate that osmotic dehydration greatly enhances the palatability of apple products in terms of appearance, taste, and texture.

• Polymer(Korea)
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• v.30 no.2
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• pp.112-117
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• 2006

To improve the type error of osmotic tablet which is one of the drug delivery system, osmotic granule could be manufactured by fluidized bed coating. It has drug layer containing different amount of osmogant and is coated with membrane including different types of binder. We confirmed that the morphology of osmotic granule was different at each coating step. The more mont of osmotic agent, the faster drug release was observed due to increasing the driving force for drug release from osmotic granule. And drug release from osmotic granule coated with membrane using different types of binder was differed by solubility of binders to water. The formation of pore in membrane was confirmed by SEM and DSC Membrane using water soluble binder released more amount of drug. From these results, we assured that difference of osmotic pressure between the inside and the outside of granule and porosity of membrane have an effect on drug release from osmotic granule.

• Clinical and Experimental Reproductive Medicine
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• v.47 no.4
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• pp.284-292
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• 2020

Objective: This study investigated whether adding outer-well medium to inhibit osmotic changes in culture media in a dry-type incubator improved the clinical outcomes of in vitro fertilization-embryo transfer (IVF-ET) cycles. Methods: In culture dishes, the osmotic changes in media (20 µL)-covered oil with or without outer-well medium (humid or dry culture conditions, respectively) were compared after 3 days of incubation in a dry-type incubator. One-step (Origio) and G1/G2 (Vitrolife) media were used. Results: The osmotic changes in the dry culture condition (308 mOsm) were higher than in the humid culture conditions (285-290 mOsm) after 3 days of incubation. In day 3 IVF-ET cycles, although the pregnancy rate did not significantly differ between the dry (46.2%) and humid culture (51.0%) groups, the rates of abortion and ongoing pregnancy were significantly better in the humid culture group (1.5% and 49.5%, respectively) than in the dry culture group (8.3% and 37.8%, respectively, p<0.05). In day 5 IVF-ET cycles, the abortion rate was significantly lower in the humid culture group (2.2%) than in the dry culture group (25.0%, p<0.01), but no statistically significant difference was observed in the rates of clinical and ongoing pregnancy between the dry (50.0% and 25.0%, respectively) and humid culture groups (59.5% and 57.3%, respectively) because of the small number of cycles. Conclusion: Hyperosmotic changes in media occurred in a dry-type incubator by evaporation, although the medium was covered with oil. These osmotic changes were efficiently inhibited by supplementation of outer-well medium, which resulted in improved pregnancy outcomes.

• Korean Journal of Food Science and Technology
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• v.21 no.2
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• pp.307-312
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• 1989

Internal mass transfer during osmotic dehydration of carrots in sugar solutions was examined as a function of concentration, temperature and immersion time of those solutions using moisture loss, sugar gain, molality and rate parameter. Influence of osmotic dehydration and blanching on browning reaction of vacuum dried carrots(3% MC: wet basis) was also evaluated. Increasing the concentration and temperature of sugar solutions increased moisture loss, sugar gain, molality and rate parameter. Water loss and sugar gain were rapid in first 4 min and then levelled off. The rate of sugar gain and molality changes on temperature was significant in lower concentration$(20^{\circ}\;Brix)$ compared to higher concentration$(60^{\circ}\;Brix)$. The changes of rate parameter were affected by concentration than by temperature of sugar solutions. Moisture loss during osmotic dehydration using a sugar solution $(60^{\circ}\;Brix,\;80^{\circ}C)$ with 20min immersion time was 55.7%. Effect of osmotic dehydration and blanching before vacuum dried to 3% MC(Wet basis) on browning reaction was significant. Minimum browning reaction during vacuum drying was carried out using pretreatments such as osmotic dehydration in sugar solution$(40^{\circ}\;Brix,\;80^{\circ}C)$ with 16 min immersion time(O.D.=0.09) and blanching with 12 min immersion time at $80^{\circ}C$(O.D.=0.31) compared to control(O.D.=1.59).

• Korean Journal of Food Science and Technology
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• v.27 no.3
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• pp.387-393
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• 1995

Diffusion coefficients of moisture and solid, reaction rate constants of carotene destruction, and the fitness of drying models for moisture transfer were determined to study the characteristics of mass transfer during osmotic dehydration. Moisture loss and solid gain were increased with increase of temperature and concentration; temperature had higher osmotic effect than concentration. Diffusion coefficient showed similar trend with osmotic effect. Diffusion coefficients of solids were larger than those of moisture because the movement of solid was faster than that of moisture at the high temperature. Reaction rate constants were affected to the greater extent by concentration changes than by temperature changes. Arrhenius equation was applied to determine the effect of temperature on diffusion coefficients and reaction rate constants. Moisture diffusion required high activation energy in $20^{\circ}Brix$, while relatively low in $60^{\circ}Brix$. To predict the diffusion coefficients and reaction rate constants, a model was established by using the optimum functions of temperature and concentration. The model had high $R^2$ value when applied to diffusion coefficients, but low when applied to reaction rate constants. Quadratic drying model was most fittable to express moisture transfer during drying. In conclusion, moisture content of carrots could be predictable during the osmotic dehydration process, and thereby mass transfer characteristics could be determined by predicted moisture content and diffusion coefficient.

• Proceedings of the Korean Society of Life Science Conference
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• 2002.12a
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• pp.48-60
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• 2002

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that stimulates the production of granulocytes, macrophages, and white blood cells. The effects of osmotic pressure on secretion of human GM-CSF into the culture medium were investigated in suspension cultures of transgenic tobacco cells. An increase in osmotic pressure caused by the addition of mannitol decreased the cell size index, with the effect being more pronounced when cells were measured wet rather than dry. Increased osmotic pressure enhanced the secretion of hGM-CSF. At 90 g/L mannitol, the maximum concentration tested, hGM-CSF was present in the culture medium at 980 ug/L. As the concentration of mannitol increased, the total amount of protein secreted also increased, but was disproportionately enriched in GM-CSF NaCl, another osmoticum, had very similar effects on cell growth and hGM-CSF production, but did not cause enrichment for hGM-CSF Additionally, protein-stabilizing polymer was added to culture broth to enhance stability of secreted recombinant protein. Finally, above two method were applied together to maximize the productivity.

• Preventive Nutrition and Food Science
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• v.8 no.3
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• pp.230-234
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• 2003

Mass transfer characteristics during osmotic dehydration of carrots were studied as functions of immersion temperature and time, and sugar and salt concentrations. The effect of osmotic dehydration on the degree of browning of air-dried carrots was also evaluated. Increasing the immersion temperature and time, sugar concentration, and salt addition increased water loss, sugar gain, molality and rate of dehydration. The water loss and increases in solids, and molality were rapid in the beginning of the process and then increased slowly during remainder of the process. Increasing 1 or 2% salt concentration in the 40$^{\circ}$Brix sugar solution at 6$0^{\circ}C$ increased water loss and solid gain. Salt addition was not able to significantly affected on water loss and solid gain compare to temperature (40～8$0^{\circ}C$) and sugar concentration (20～60$^{\circ}$Brix) changes due to the low salt concentration. A minimum degree of browning of the air-dried carrots (O.D. = 0.048) could be achieved using binary solutions (40$^{\circ}$Brix sugar solution with 2% salt addition) with 24 min of immersion time compared to control (O.D. = 1.308) or blanching with 24 min of immersion time (O.D. = 0.174).

• The Korean Journal of Physiology
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• v.8 no.1
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• pp.45-53
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• 1974

The effects of kanendomycin on the potassium permeability in the rabbit erythrocyte membrane are investigated and the results are summarized as follows. 1. Kanendomycin causes the efflux of $K^+\;and\;influx\;of\;Na^+$ across the rabbit erythrocyte membrane. 2. Osmotic resistance of kanendomycin treated erythrocytes is diminished. This diminution of osmotic resistance is more pronounced by increasing concentration of kanendomycin and longer incubation time. But osmotic resistance is rather increased in the presence of lower concentration of kanendomycin. 3. Cysteine and glutathione have little influence on $K^+$ efflux induced by kanendomycin. 4. EDTA has no effect on the increase in $K^+$ outflux by kanendomycin while PCMB augments slightly on $K^+$ outflux. 5. Kanendomycin inhibits $Ca^{++}$ binding competitively to rabbit erythrocyte membrane fragments.

• Transactions of the Korean hydrogen and new energy society
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• v.14 no.3
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• pp.195-206
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• 2003

Polymer electrolyte membrane fuel cells(PEMFC) are very interesting power source due to high power density, simple construction and operation at low temperature. But they have problems such as high cost, improvement of performance and effect of temperature. This problems can be approached using mathematical models which are useful tools for analysis and optimization of fuel cell performance and for heat and water management, in this paper, transient model consists of various energy terms associated with fuel cell operation using the mass and energy balance equation. And water transfer in the membrane is composed of back diffusion and electro-osmotic drag. The temperature calculated by transient model approximately agreed with the temperature measured by experiment in constant current condition.

• Journal of Ecology and Environment
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• v.29 no.4
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• pp.361-364
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• 2006

The objective of the current study was to characterize and apply multiple regression model relating to vegetation values of the plant species over salt marshes. For each salt marsh community, vegetation and soil variables were investigated in the western coast and the southern coast in South Korea. Osmotic potential of soil and $Cl^-$ content of soil as independent variable had positive and negative influences on vegetation values. Multiple regression model showed that vegetation values of 14 coastal plant communities were determined by pH of soil, osmotic potential of soil and sand content. The multiple regression equation may be applied to the explanation of distribution and abundance of plant communities with exiting ordination plots.