• 한방재활의학과학회지
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• 제23권3호
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• pp.69-78
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• 2013

Objectives The purpose of this study was to investigate the effectiveness of the Gongjin-dan (Gongchen-dan, here in after GJD) in order to obtain the evidence for clinical application. Methods The GJD-related articles published from 1990 to 2013 were searched using "Korean Traditional Knowledge Portal", "Oriental Medicine Advanced Searching Integrated System (OASIS)", "Korean Association of Medical Journal Edition (Koreamed)", "Research Information Services (RISS4U)", "Korean Medicine Database (KMbase)", "National Discovery for Science Leader (NDSL)", "PubMed", "China National Knowledge Infrastructure (CNKI)". The search keywords were "Gongjin-dan", "Gongchen-dan". Thirty-nine articles were obtained. After excluding the eighteen article which did not meet inclusion criteria, finally twenty-one articles were included; five clinical articles and sixteen experimental articles. Results In clinical studies, GJD has the various effectiveness in cardiovascular diseases, alcoholic hepatitis, mild dementia, anemia. Also experimental studies related to the GJD show a variety of effects, such as anti-oxidative activity, neuroprotective activity, hepatoprotective activity, anti-inflammatory activity, immunological activity, reproductive recovery activity with fewer side-effects. Conclusions It has been suggested that there are various effects of GJD in treating a wide-range disease. However, in order to put GJD to use for many kinds of diseases in more reasonable ways, it is needed to publish well-design clinical trial based on the variety of results of experimental studies.

• 한국한의학연구원논문집
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• 제13권1호통권19호
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• pp.125-128
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• 2007

Objective : This study aims to review the current status and problems of Korean Medicine and attempts to come up with the means to present a comprehensive and effective set of statistical data. Methods : We have analyzed the current statistics and tried to show how to establish an effective system to gather and organize statistics related to Korean Medicine, including national surveys by the Ministry of Health and Welfare or other relevant insititutions. Results : The existing statistics in Korean Medicine were established not as a result of national demand based on comprehensive analysis but due to the demand of the government ministries such as the Ministry of Health and Welfare or other relevant institutions. Thus, the statistics have been revealed to possess limitations such as a lack of systemization and consistency. In addition, the statistics analyze only the current industrial status of Korean Medicine, and as a result the information in unable to show systematic data for innovation, which is indispensable for the advancement and development of the Korean Medicine industry. Conclusion : To improve the statistical data in Korean Medicine, the statistics need to get over not only the level of management or regulation in Korean Medicine, but also the production of fragmentary statistics. It has to ultimately reflect the innovative activities in Korean Medicine nationally, and show what we need to advance and develop the industry.

• 동의생리병리학회지
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• 제27권6호
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• pp.717-729
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• 2013

Bioelectrical Impedance Analysis (BIA) is a non-invasive and low-cost technique that estimates body composition based on the distribution of water and electrolytes in the body by analyzing body's electrical responses to source voltages. In this work, we carried out a systematic literature review on BIA researches in traditional East Asian medicine (TEAM). For comparison, firstly we introduced the concept and principle of BIA, and offered a general overview of research trends in western medical perspectives. We searched through the databases of Oriental Medicine Advanced Searching Integrated System and DataBase Periodical Information Academic for the articles published between 1994 and 2013, with keywords such as 'BIA', 'bioelectrical impedance' and 'impedance'. Among the rough-searched 274 articles, we finally selected 21 articles appropriate to the intended research field. The selected articles were categorized into diagnosis in Sasang medicine, impedance analysis in meridian system, and change of body composition after taking herbal medicine. We found that most of BIA researches in TEAM were preliminary and remained in the peripheral levels which is far behind the western medical research activities. Therefore, more efforts are needed to study BIA in association with major subjects such as pattern identification or physiological/pathological phenomena. In addition, methodological breakthrough of BIA is possible by applying the diagnostic concepts of the TEAM in relation to the balance of Qi and Blood.

• 대한약침학회지
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• 제16권1호
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• pp.12-20
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• 2013

Objective: Standard cancer therapy prolongs survival, but can be detrimental to the quality of life, compromise the immune system, and leave residual disease that can cause recurrence years or decades in the future. Tumor dormancy therapy is a novel therapeutic approach that may improve these shortcomings, promote quality of life, and prolong survival. The aim of this study was to analyze studies on dormancy therapy, especially studies using traditional Oriental herbal medicine, so as to evaluate the efficacy of dormancy therapy with traditional oriental herbal medicine. Methods: We conducted a systematic literature review using Scientific and Technical Information Integration Services (NDSL), PubMed, and RISS. We searched for clinical reports, papers, and books related to tumor metastasis, recurrence, immunotherapy, tumor dormancy, and traditional oriental herbal medicine with anticancer effects. Seventy-nine (79) experimental and clinical articles in both Korean and English were reviewed. This study was conducted from March 1, 2012 to May 31, 2012. Results: This approach, Tumor dormancy therapy, rather than seeking to remove the tumor, includes combination of low-dose chemotherapy, immunotherapy, immunosurveillance, and other methods to stabilize tumor growth and to enhance the host is immunity against disseminated tumor cells and thus to manage cancer as a chronic disease while maintaining quality of life. In particular, integrative use of Oriental herbal medicine has been shown to induce or maintain tumor dormancy, increase the effectiveness of conventional chemotherapy, improve quality of life, and prolong survival. Conclusion: Tumor dormancy therapy is a promising novel therapeutic approach that may be especially effective with Oriental herbal medicine. Further research is needed to determine its potential mechanisms and therapeutic applications.

• 대한한의학회지
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• 제25권3호
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• pp.20-31
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• 2004

The 21/sup st/ century is a society based on knowledge, so in economic activities, it has emphasized the importance of information such as intellectual property or intangible asserts. Especially, according to the agreement on trade related as parts of intellectual property rights in WTO, it is used as the method of commercial entente and monopoly for intellectual property in an advanced nation. For this reason, WIPO and UNESCO discussed a complement for intellectual property on the foundation of traditional knowledge such as traditional knowledge (TK), genetic resources (GR) and traditional cultural expressions (TCE, folklore). Korea has a lot of knowledge falling under TK, GR, and TCE because of the long history of the country. In the case of traditional medical care, it has been used in the public health system. It is hard to apply these rights to traditional medical care of Korea because the laws of intellectual property have been established under the ideas of western culture. It is necessary to improve the classification system of traditional knowledge and patents. In the patent classified system of IPC, it needs to be related to the research between the classified system for massive technology and the classified system for traditional clinic technology.

• 한국한의학연구원논문집
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• 제15권1호
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• pp.69-78
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• 2009

Objectives : To understand the basis for future improvement and development in the lectures, an evaluation was made on the lecture by the 'theory-practice-self study' system initiated in 'Yangseng Qigong(養生氣功) and practice' at Daegu Haani University. Method : We surveyed the satisfaction of 'Yangsaeng Qigon and Practice' which is the lecture that is composed theory, practice, self study for 120 students at college of oriental medicine in Daegu Haani University. Result : In the inquiry for the satisfaction with the general class of 'Yangsaeng Qigong and practice', 69% of students answered positively. As to the satisfaction with class grouping, 76% answered affirmatively, and as to the question "Agreement to the plan workable?", 72% said it was satisfactory, showing lectures by class grouping were made successful as planed. As to satisfaction with theory lectures, 36% were satisfied (38% unsatisfied), as to practice 90% was satisfied (2% unsatisfied) and as to the self-study and special lectures, 36% was satisfied (23% unsatisfied), showing the satisfaction was relatively higher for practice. To the question "Was it helpful in understanding hygiene Danjeon-breathing science?", 31% said yes (16% no) for theory, 87% yes (3% no) for practices, 32% yes (32% no) for special lectures, and 37% yes (28% no) for team assignments. Conclusions : The textbooks and majors of the lecturers turned out to be varied, but as seen from the result of lecture satisfaction on 'Yangseng Qigong and practice', it was different according to the preparedness of the lecturers and satisfaction with the lecture material. Despite the situation that most schools have chosen it as a major subject, the subject name was divergent among schools and the textbook and the content of practice were also not unified. At the point of globally rising interest in Qigong, this will only lead to its weak competitiveness when advancing to the world.

• 대한한의학회지
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• 제31권3호
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• pp.17-27
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• 2010

Objectives: Cocaine has been well known as a representative drug of abuse for its strong reinforcing effect linked to the mesolimbic reward system including dopamine, and such reinforcement leads to the addiction. Acupuncture has been used widely in eastern Asia for the treatment of various diseases including mental disorders and psychiatric problems, and is gathering more interest as one of the complementary and alternative medicines in western countries. In a previous study, we demonstrated that acupuncture at HT7 could affect dopamine release in the mesolimbic system of rats sensitized to alcohol and morphine. This study was designed to investigate whether acupuncture at HT7 could attenuate cocaine intake or not. Material & Methods: Male Sprague-Dawley rats weighing 270-300 g at the start of experiment were trained to self-administer food pellets under a fixed ratio 1 schedule. After the success of acquisition of 100 pellets within 3 h for 3 consecutive days, animals were subjected to surgery whereby Silastic tubing was implanted into right jugular vein and secured with mesh under the anesthetization using pentobarbital injection (50 mg/kg, i.p.). Following recovery, rats were trained to self-administer cocaine (0.25 mg/kg) in daily 2 h sessions under fixed ratio 1 schedule over 10 days. Each treatment was performed on the next day of each establishment of baseline. Results: Results show that acupuncture at HT7, but not at control points, reduced cocaine intake significantly. Acupuncture at HT7 decreased selectively active lever response from $63.15{\pm}3.35$ to $51.46{\pm}3.99$ corresponding $82.12{\pm}5.31%$ compared to basal level. Also, it was demonstrated that the effect of acupuncture was mainly occurred at the half period. Nevertheless, acupuncture at HT7 did not influence the food taking behavior. Conclusions: From the results of this study, it may be suggested that acupuncture at HT7, at least in part, could contribute to the treatment of cocaine abuse.

• 한방비만학회지
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• 제7권1호
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• pp.39-54
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• 2007

Objectives : This study has been done to know which herbs and herbal formulae are frequently used for the treatment of obesity in Korea and overseas since 2000. Methods : We conducted a computerized literature search in KISS (Korean studies Information Service System), Pubmed, Journal of Oriental Association for Study of Obesity ,and Journal of Oriental Rehabilitation Medicine(2000 -Apr. 2006) using search key words obesity, obese, weight loss, weight control combined with herb, herbal formula. Result and conclusion : Seventy-two studies have been identified(50 Korean papers and 22 pubmed papers) and 81 herbs have been found. In USA it was mainly used as single herb for food, but in Korea it was mainly used as herbal formula. For single herb, ephedra(麻黃) was the most studied single herb both in Korea and the USA. For herbal formulae, Sasang Constitutional Medicine(SCM, 19times) was the most frequently used herbal formula, in which the herbs for Tae-eum type person like Taeyeumjowui-tang(太陰調胃湯, 7times) and Choweseungcheng-tang(調胃升淸湯, 5times) were mainly prescribed. The next was Chegameuiin-tang(體減薏苡仁湯, 11times) and Bangpungtongsungsan( 防風通聖散, 3times). Calculating each herb consisted in each herbal formula, Coicis Semen(薏苡仁), Angelicae gigantis Radix(當歸), and Glycyrrhizae Radix(甘草), Raspberry Ketone, Cnidii Rhizoma(川芎), and Ephedra Herba(麻黃) turned out to be the most frequently used herb.

• 동의생리병리학회지
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• 제22권3호
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• pp.691-698
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• 2008

The aims of this study are to search herbal medicines that have anti-aging, anti-wrinkle, anti-oxidant and whitening effects. This is preliminary study as a finding for excellent and specific natural agents which inhibit the skin aging and whitening formation. In this study, the articles and the documents, which have been published in domestically or internationally, have been searched and analyzed. Articles were gathered by taking advantage of Society of Cosmetic Scientists of Korea's documents, Pub med database, Korean Medical Database and Korean Studies Information Service System. Among the many species of herbal medicines, we selected the herbal medicines showing superoxide scavenging activities, and 1.1-diphenyl-2-picrylhydrazyl(DPPH) scavenging effects. The herbal medicines were showed anti-wrinkle effects on Metrixmetallo proteinase (MMP-1) inhibition activity and elastase inhibition activity. Also we found herbal medicines that have highly effect of tyrosinase inhibition, L- DOPA inhibition and melanin synthesis inhibition.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2001년도 하계종합학술대회 논문집(5)
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• pp.77-80
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• 2001

In this paper, we devised volume pulse detection system which can quantitatively represent a artery elasticity for oriental clinic. Volume pulse wave detecter system consist of transducer which has IRLED-photodiode detecter, temperature sensor and filter and preprocessing circuits, data conversion and serial communication parts, and computer system. The high-pass filter are detect volume pulse wave and lowpass filter detect tissue thickness. The detected volume pulse wave are normalized by tissue thickness value with a division process. As the result of experiment, we can detect normalized volume pulse wave with effectively.