• 한국식품영양학회지
• /
• 제22권2호
• /
• pp.261-271
• /
• 2009

Deep sea water exists at depths of over 200m under the sea. As no sunlight reaches it, photosynthesis does not take place within it, and it contains no organic matter. In addition, its temperature is maintained at a stable low level throughout the year, so it does not get mixed with the sea water on the surface. It contains a large amount of nutritious salts, whose cleanness is maintained. It is a marine resource that has matured for a long period of time. Research into deep sea water, which started in the 1970s, has been made around the whole world, including the USA and Japan. In Korea, research has been active in this area since 2000. As there has been a good amount of research into industrial applications for deep sea water, since 1993, patents for the relevant technologies have been applied. This paper intends to provide a resource to researchers of deep sea water, by summarizing of all domestic deep sea water-related patents applied with Korean Intellectual Property Office from 1993 to 2008. This research was conducted using a computer and KIPRIS Database owned by the Korea Institute of Patent Information. 'Deep sea water' was used as the search keyword. A total of 222 Korean patents relating to deep sea water have been registered on the basis of IPC. Of these, 126 patents relate to the manufacturing and the treatment of foods, foodstuffs, or non-alcoholic beverages(A23L), while 50 patents relate to the production for medical, dental, or cosmetic purposes(A61K). 38 patents relate to water purification, treatment of wastewater, sewage and sludge (C02F), while 8 patents relate to fishery and farming(A01K). In summary, it was found that studies for the practical use of deep sea water have been conducted in relation to the manufacturing and the treatment of foods, foodstuffs, beverages, and cosmetics.

• 한국환경과학회지
• /
• 제23권1호
• /
• pp.89-96
• /
• 2014

Styela clava tunic is generated in large amounts as a waste from S. clava processing plants and causes environmental problem. Although biological activities of S. clava were reported by many investigators, study on S. clava tunic was little. In this study, therefore, tyrosinase inhibition and antioxidative activities of extracts from S. clava tunic using different solvent were investigated for recycling of the fishery waste. Among extraction methods tested, autoclaved extraction (25.7%) and hot water extraction (18.2%) appeared to be effective for extraction. The highest total phenolic content was 46.6 mg/g in autoclaved extract while the highest flavonoid content was 23.0 mg/g in chloroform extract. All extracts possessed tyrosinase inhibition activity and the inhibition activity was concentration-dependent. Inhibition concentration ($IC_{50}$) against tyrosinase activity was $0.36{\times}10^4$ mg/ml in ethanol extract, $0.11{\times}10^3$ mg/ml in acetone extract and 0.27 mg/ml in n-butanol extract. Among extracts tested, hot water and autoclaved extracts displayed higher antioxidative activity than organic solvent extracts. Therefore, our data suggest that extract from S. clava tunic may potential candidate for cosmetic product with whitening effect and medicine for diseases caused by various oxidative stresses.

• 한국의류학회지
• /
• 제34권2호
• /
• pp.318-335
• /
• 2010

This study is to enhance the competitiveness of the domestic cosmetic industry and provide basic materials needed for a design idea by analyzing perfume bottles designed by Rene Lalique. The methods of this study are documentary research and demonstrative research. The documentary research considered the theoretical background with a focus on related domestic and international literature, previous research, and Internet materials. The demonstrative research extracted photo materials of the bottle designs of Lalique from domestic and international web sites along with literature that classified them into shapes, colors, materials, and patterns that analyzed the general characteristics and chronologic changes. The results of this study are as follows. The curve-oriented shape was common and multi-colors were used more frequently than a single color in the 1910's. Colorless-transparent glass and a flower patterns were used frequently for materials and patterns, respectively. Lalique reflects this style in his bottle designs because the Art Nouveau effect in the 1910's. In the 1920's, curved and straight shapes had a similar percentage. The use of multi-colors and one type of glass bottle increased versus the 1910's. Similar to the 1910's, a flower pattern was used most frequently. This suggests that Lalique was influenced by the established Art Nouveau and was also interested in the Art Deco style, In the 1930's, an organic curved shape was common. Unlike the 1910's and 1920's, a single color was more common than multi-colors. The one type of glass bottle and a geometric pattern were common for materials and patterns, respectively. The Art Deco style was reflected in the bottle design of Lalique in the 1930's.

• 대한화장품학회:학술대회논문집
• /
• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book II
• /
• pp.245-252
• /
• 2003

There have been many kinds of hair styling sprays with various setting effects. Consumers have used strong setting effect hair sprays to get a long lasting hold. In recent years, however, more and more consumers have come to prefer a "soft ＆ natural" touch feeling, keeping the same long lasting hold. Nonetheless, the existing approaches to this feature could not respond to the consumers′ needs, since products lose the hold strength if the soft feeling is pursued, and vice versa. We have researched and developed a new products to attain a compatible feature with both long lasting hold and natural feeling. Then, we have developed a new multifunctional hair styling material "Poly Amino Acid Derivative (PAAD)." We have focused on the PAAD′s feature that highly diffuses onto a hair and makes thin and even layer on a hair, and have made trials and errors to improve holding strength. "P AAD" excellently makes hair memorize its curl shape which is as the same effect as existing ordinary acrylic resin. Further more, it leaves a soft and natural touch feeling on the hair. We have accomplished a new Poly Amino Acid Derivative with ambivalent features, "soft ＆ natural finish" and "long lasting hold ", and now we report about it.

• KSBB Journal
• /
• 제23권6호
• /
• pp.546-550
• /
• 2008

본 연구에서는 아스타잔틴의 각종 유기용매와 물에 대한 용해도와 산화, 빛, 온도 및 pH에 의한 아스타잔틴의 안정성을 검토하였다. 아스타잔틴은 유기용매인 아세톤과 아세트산에 비교적 용해도가 높았으며 물에는 거의 용해되지 않았다. 아스타잔틴의 용해도에 미치는 pH의 영향을 검토한 결과, 산성 조건 (pH 2)에서는 중성이나 염기성 조건에 비하여 용해도가 10-20배 증가하였다. 아스타잔틴은 산화와 빛에 대한 안정성이 매우 낮았으며, pH 3에서도 안정성이 급격히 떨어지는 것으로 조사되었다. 온도에 대한 영향을 조사한 결과, 상온 보관시에도 아스타잔틴이 쉽게 분해되었으며, 특히 $100^{\circ}C$에서 5초 동안 가열할 경우 아스타잔틴이 90% 이상 분해되었다. 결론적으로 아스타잔틴을 식품이나 화장품 등의 산업적 활용을 위해서는 안정성과 용해도 개선이 요구되는 것으로 판단되었다.

• Journal of Applied Biological Chemistry
• /
• 제57권2호
• /
• pp.123-129
• /
• 2014

The antioxidant and antimicrobial activities of Camellia oleifera seed oil were studied. Four kinds of seed oil samples were prepared, crude oil and refined oil, extracted by cold pressing method (CPC, CPR), and organic solvent extraction (OSC, OSR). Antioxidant activity analysis was measured in 2,2-azinobis (3-ethylbenzothiazoline-6-sulfonic acid)-diammonium salt, ferric reducing Ability of Plasma, and 2,2-diphenyl-1-picrylhydrazyl assays. Besides, the percentage of inhibition of red blood cells hemolysis induced by 2,2'-azobis(2-amidnopropane) dihydrochlorid, the lag time of LDL conjugated dienes formation in vitro, and the inhibitors of loss in tryptophan fluorescence were all used to estimate the antioxidant activity of the samples. The total phenolic contents (TPC) were detemined by Folin-Ciocalteu method. The TPC of the C. oleifera seed oils can be arranged in descending order: CPC ($1.9172{\mu}g/mL$) > OSC ($1.5218{\mu}g/mL$) > CPR ($1.0611{\mu}g/mL$) > OSR ($0.6782{\mu}g/mL$). And the oils were investigated for activity against Escherichia coli, Bacillus subtilis, Saccharomyces cerevisiae and Aspergillus niger. The results showed the antioxidant activity of crude oil by cold pressing method was stronger than others, and all oils did inhibit activity of the top three bacteria expert A. niger. The further significance of the study contributes to measure the antioxidant and antimicrobial activity of the potential health benefits by the different methods of preparation and the oil of C. oleifera seeds acting as free radical scavenger, pharmaceuticals and preservatives may offer some information in medicine and cosmetic not just in food field.

• 접착 및 계면
• /
• 제13권4호
• /
• pp.163-170
• /
• 2012

${\beta}$-cyclodextrin은 다른 분자를 포접하여 inclusion complex (포접착물)를 만드는 특성을 가지고 있기 때문에 의약품, 농약, 식품, 화장품, 산화방지제, 휘발방지제, 흡습방지제, 퇴색방지제, 유화제 등의 다양한 용도로 사용되고 있다. 이러한 장점에도 불구하고 ${\beta}$-cyclodextrin은 물이나 유기용매에 대한 용해도가 낮아 사용에 제약을 받아왔다. 본 연구에서는 이러한 문제를 해결하기 위해서 Bisphenol-A나 폴리우레탄(PU) 발포제인 cyclopropane에 대한 포접특성을 갖고 물이나 유기용매에 대한 용해도가 향상된 polyol type의 ${\beta}$-cyclodextrin 유도체를 합성한 후 그 특성을 고찰하였다. 연구결과 합성된 polyol을 사용해서 제조한 경질 PU foam은 기존의 polyol과 비교해서 더 우수한 열전도 특성과 압축강도를 나타내었다.

• 공업화학
• /
• 제30권2호
• /
• pp.254-259
• /
• 2019

본 연구에서는 마그네슘-층상규산염(MgP) 층간에 솔잎 추출물(PLE)이 삽입되어 겹겹이 쌓여있는 샌드위치 구조의 나노입자(PLE/MgP)를 one-pot으로 합성하였다. XRD 분석을 통해 팔면체와 사면체 구조로 MgP가 성공적으로 합성되었으며, PLE가 층간에 삽입되어 MgP 간의 층간거리(d-spacing)가 벌어진 것을 확인하였다. HR-TEM을 통해 모폴로지 변화를 관찰하였으며, 열중량분석법을 통해 PLE가 MgP 대비 10%까지 함유된 것을 확인하였다. 최소저해농도(MIC) 및 최소 사멸농도(MBC) 분석을 통해 피부 상재균에 대한 항균 활성을 검토한 결과 MgP 또는 PLE보다 PLE/MgP의 항균 활성이 더욱 향상된 것을 확인하였다. 이러한 결과는 본 연구에서 개발한 PLE/MgP 유/무기 복합 소재가 화장품 소재, 의료용 소재 등의 다양한 분야에 적용 가능함을 확인하였다.

• 대한화장품학회:학술대회논문집
• /
• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
• /
• pp.338-351
• /
• 2003

UV radiation is the most dangerous stress factor among permanent environmental impacts on human skin. Consequences of UV exposure are aberrant tissue architecture, alterations in skin cells including functional changes. Nowadays new kinds of outdoor leisure-time activities and changing environmental conditions make the question of sun protection more important than ever. It is necessary to recognize that self-confident consumers do not consider to change their way of life, they demand modern solutions on the basis of new scientific developments. In the past one fundamental principle of cosmetics was the use of physical and organic filter systems against damaging UV-rays. Today new research results demonstrate that natural protecting cell mechanisms can be activated. Suitable biological actives strongly support the protection function not from the surface but from the inside of the cell. A soy seed preparation (SSP) was proven to stimulate natural skin protective functions. The major functions are an increased energy level and the prevention of DNA damage. These functions can I be defined as biological UV protection. The tumor suppressor protein p53 plays a key role in the regulation of DNA repair. p53 must be transferred into the phosphorylated form to work as transcription factor for genes which are regulating the cell cycle or organizing DNA repair. A pretreatment with SSP increases the phosphorylation rate of p53 of chronically UV-irradiated human keratinocytes significantly. According to the same test procedure SSP induces a dramatic increase in the expression of the tumor suppressor protein p14$^{ARF}$ that is supporting the p53 activity by blocking the antagonist of p53, the oncoprotein Mdm2. Mdm2, a ubiquitin E3-ligase, downregulates p53 and at the same time it prevents phosphorylation of p53. The positive influence of the tumor suppressor proteins explains the stimulation of DNA repair and prevention of sunburn cell formation by SSP, which was proven in cell culture experiments. In vivo the increased skin tolerance against UV irradiation by SSP could be confirmed too. We have assumed, that an increased repair potential provides full cell functionality.y.

• 대한화장품학회:학술대회논문집
• /
• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
• /
• pp.719-732
• /
• 2003

A kojic acid derivative, kojic acid 7-O-$\beta$-D-tetraacetylglucopyranoside(KTG) was synthesized. Regio-and stereo-selective glycosylation at 7-postion in kojic acid with $\beta$-D-pentaacetylglucose was achieved with high yield(80％) by the use of Lewis acid and organic base in nonpolar solvent. KTG was hydrolyzed in methanol by the aid of sodium methoxide to give kojic acid 7-O-$\beta$-D-glucopyranoside(KGP). KGP is freely soluble in water and soluble in methanol and ethanol. Its structure was comfirmed by $^1$H-NMR and $^{13}$ C-NMR. Tyrosinase activity inhibition of KGP was measured with mushroom tyrosinase compared with ascorbic acid, kojic acid and arbutin. KGP showed higher tyrosinase inhibition activity($IC_{50}$/=33.3 $\mu\textrm{g}$/ml) than ascorbic acid(63.2 $\mu\textrm{g}$/ml) and arbutin(91.8 $\mu\textrm{g}$/ml) but lower inhibition activity than kojic acid(8.3 $\mu\textrm{g}$/ml). To test free-radical scavenging activity, we used 1, 1-diphenyl-2-picrylhydrazyl(DPPH) as a free-radical source. Free-radical scavenging activity of KGP was very low($SC_{50}$/>1000 $\mu\textrm{g}$/ml) compared with ascorbic acid($SC_{50}$/=2.68 $\mu\textrm{g}$/ml) and arbutin($SC_{50}$/=180$\mu\textrm{g}$/ml). Melanin formation inhibition of KGP was measured in B16 melanoma, compared with kojic acid, arbutin and Vitamin C. Inhibition activity of KGP for melanin formation was not found within test concentrations.