• Journal of the Korean Society of Food Science and Nutrition
• /
• v.42 no.12
• /
• pp.2076-2081
• /
• 2013

The objective of this study is to investigate the gastric emptying and gastrointestinal transit improvement effect of DL-methionine methylsulfonium chloride (MMSC) in functional dyspepsia animal models. Cisplatin causes nausea, vomiting, and inhibition of gastric emptying. Rats were divided into four groups: G1 (normal group), G2 (gastric emptying induced by cisplatin), G3 (gastric emptying induced by cisplatin with itopride 30 mg/kg pretreatment), and G4 (gastric emptying induced by cisplatin with MMSC 4 mg/kg pretreatment). Immediately after an oral administration of a liquid meal (phenol red), delayed gastric emptying was induced by cisplatin (10 mg/kg (i.p.)). After 20 min in the cisplatin administration, the animals were sacrificed. In rats treated with cisplatin, the gastric emptying rate was significantly reduced. On the other hand, MMSC reversed the reduction of gastric emptying induced by cisplatin. And also, MMSC caused to travel FITC-dextran more significantly longer distance than the control, which is based on the values of the mean geometric center in the atropine driven delayed gastrointestinal transit animal models. Furthermore, MMSC drastically increased the gastrointestinal transit in rats, considerably increased the values of the mean geometric center (MGC), compared to the control, which was comparable to that of mosapride. These results suggest that MMSC could be an effective component for the treatment of functional dyspepsia.

• Journal of Preventive Medicine and Public Health
• /
• v.1 no.1
• /
• pp.25-36
• /
• 1968

Introduction In order to improve medical education through the introduction of a concept of comprehensive health care of a community, an area surrounding the University Campus was chosen for the Community Health Service Project. It has been on operation for last 4 years with its major emphasis on family planning services, and maternal and child health care. The major objectives of this survey at the area are to obtain: 1) The demographic data, 2) The health need and trend of medical care, 3) The attitude and practice in maternity care to be used for further improvement of the planning and the services of the project. Population and Survey Method Out of three Dongs of the Community Health Service Area, only two Dongs namely Changchun and Yonhee were selected for the survey. Total number of households and population in the area studied was 3,683 and 21,857 respectively. An interview was performed with questionnaire schedule which was recorded by interviewers. This includes the degree of utilization of health services provided by the Community Health Service Program such as family planning, prenatal care during their last pregnancy, delivery history and complications of the delivery as well as the incidence of illnesses in general. Prior to the interview, all interviewers were trained for interviewing technique for two days. The survey was carried out during the period from October December 1967. Results 1) Demographic Data : 41.3% of the population studied were children under age 15 and only 3.5% were over 60 years of age. Crude birth rate and crude death rate of this area studied during the period of November 1966-October 1967 were 20.5 and 7.7 respectively. Infant mortality rate during the same period was 35.9. 50.4% of the 2,832 households fell into the category of middle class, 39.8% to the lower class and 9.5% to the upper class in economic condition. 19.8% of 2,832 householders had no formal education, 22.7% primary school, and 57.5% middle or higher school education. 2) Health Status and Utilization of the Community Health Service: Those who suffered from many illnesses during the month of October, 1967 were 690(4.6% of 14,891 persons). Classification of these patients into the type of disease shown respiratory diseases 27.4%, gastrointestinal diseases 18.1%, tuberculosis 10.9%, skin and genitourethral diseases 4.5% and gynecologic patients 4.5%. Only 55.9% of the patients received medical care at hospital or doctor's clinic. But among TB and gynecologic patients, 70.7% and 72.4% were treated at medical facilities. 10.6% of 2,832 householders interviewed has ever utilized the Community Health Service Program provided by the Yonsei Medical School, Classifying these clients into the type of service, 35.9% utilized the wellbaby clinic, 31.0% the family planning clinic, 14.7% the home delivery care, and the rest utilized other services such as the premarital guidance cinlic and the sanitary inspection service. 3) Maternity Care: 23.6% of 2,151 deliveries were done at medical facilities such as hospital, private clinic, while 76.4% were done at home. Acceptance rate of prenatal care was 32.6% as whole, but 49.6 of 774 women who had the prenatal care service had their deliveries at medical facility. 45.1% of total deliveries were attended by medical and or paramedical personnel. 75.8% of the deliveries of those received prenatal care were attended by medical and or paramedical personnel while only 27.8% of the deliveries of those who did not have prenatal care attended by medical and or paramedical personnel. 49.8% of deliveries of the upper class, 29.8% of the middle class and 9.9% of the lower class were attended by medical and or paramedical personnel. 6.2, 3.3% and 24.8% of mothers reported about their xeperience of edema, coma and fever during the period of trimester of pregnancy and puerperium. 4) Family Planning: The rate of practice of family planning was 27.9%. 31.7% of them were by IUD, 2.9% by oral pill, 15.2% by sterilization and the rest by traditional methods. Those women who had 3 to 4 children had highest(30.2%). Practice rate among the various methods of family planning, oral pill was the most popular method to whom had 2 or less children. In relation between the practicing rate of family planning and living standard, the upper, middle and lower class practiced 37.5, 29.4 and 19.9% respectively.

• Journal of Korean Medicine Rehabilitation
• /
• v.18 no.1
• /
• pp.111-123
• /
• 2008

Objectives : The objective of this study was to investigate the outcomes of functional electrical stimulation (FES) which was applied twice a day in patients with dysphagia after stroke. Methods : Eleven patients with dysphagia after stroke were participated. The electrical stimulator with two channels was employed for forty minutes daily or forty minutes twice a day for fifteen days. Participants were divided into two groups by random method; The FES was performed twice a day for Twice-FES group (n=6), and once a day for Standard-FES group (n=5). For evaluation of dysphagia, the functional dysphagia scale by videofluoroscopic swallowing study, and swallow function scoring system by six clinical swallowing stage were assessed at pre- and post-treatment. Results : In both groups, there was a significant decrease of total functional dysphagia scales after FES treatment (p<0.05) and the results mainly affected the pharyngeal phase of deglutition. There was no significant difference between the two groups in total functional dysphagia scales, but the Twice-FES group had a decreased residue in oral cavity compared to the standard FES group. In both groups, there were significant improvements in swallow function scoring system (p<0.05). The twice-FES group had more high clinical swallowing stages. Conclusions : The results demonstrated that FES is a clinically effective intervention in treatment of stroke patients with dysphagia. Moreover, the treatment applied twice a day had relatively positive effects on the reduction of oral cavity residue and the improvement of clinical swallowing stage.

• Journal of Periodontal and Implant Science
• /
• v.29 no.4
• /
• pp.725-737
• /
• 1999

The present study was performed to evaluate the clinical effects following local application of 30% minocycline strip(polycaprolactone), 2% minocycline gel(hydrocarbon gel) and 12% minocycline strip(polylactide, Minodent) to augment scaling and root planing in patients with chronic adult periodontitis. Forty teeth with periodontitis were enrolled in the study anddistributed into 4 groups including control group. All patients performed standardized oral hygiene instructions and mechanical debridement at the beginning of the study and then each local delivery drugs were inserted into periodontal pocket in each groups. Examinations regarding plaque index(PI), papillary bleeding index (PBI), probing pocket depth (PPD) were carried out at 0, 2, 4 weeks. All experimental groups showed statistically significant differences between baseline and 2 and 4 weeks in every clinical indices. Especially, 30%minocycline strip and Minodent group showed a significant improvement in PBI at 2 weeks and in PPD at 2 and 4 weeks. In conclusion, highly bio-resorbable Minodent delivered subgingivally as an adjunct to scaling and root planing induces better clinical effects for periodontal health than 2% minocycline gel and control group.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.34 no.3
• /
• pp.112-126
• /
• 2021

Objectives : The purpose of this study is to report the effectiveness of Korean medical treatments on chronic glossitis using Yanggyeok-sangagam based on tutakbeop(透托法), and Ikgibohyeol-tanggagam based on botakbeop(補托法) and bobeop(補法). Methods : We treated a 83-year-old female patient who had glossitis by Korean medicine and acupuncture treatment. These treatments were performed from 2020.8.4. to 2021.3.4. We have confirmed the improvement of white plaque like a pseudomembranous pattern lesion and pain. We recorded images that include change of symptoms. Results : After the treatments were done, the scores of numeric rating scale(NRS), oral assessment guide(OAG) and oral health impact profile-14(OHIP-14) were decreased. The NRS score was decreased from 7 to 1. The OAG score was decreased from 20 to 9. The OHIP-14 score was decreased from 34 to 5. Conclusions : According to the result, Korean medical treatments such as Korean medicine and acupuncture treatment, followed by the cure rules- tutakbeop(透托法), botakbeop(補托法) and bobeop(補法) can be effective for the treatment of chronic glossitis.

• Korean Journal of Health Education and Promotion
• /
• v.10 no.1
• /
• pp.34-60
• /
• 1993

This study was done for the improvement of dental health of rural villagers and the dental health education, through finding of the types of brushing teeth and dental treatment of 812 people in Sunsan, Kyungpook province for 35days from March 27 to April 30 in 1992. Summaries are as follows ; 1. 58.5 percent of respondents were women, 56.3 percent were 40′s, 28.0 percent were 30′s, 12.3 percent were 50′s, and the over 60′s were 3.4 percent Elementary school graduates were 36.1 percent and most of them were middle school graduates, 33.5 percent. In view of the occupation, farmers were 56.5 percent, factory workers were 17.9 percent, the middle class (monthly pay amounting to 500,000∼990,000 won) were 49 percent and the lower class(less than 500,000 won) were 30.9 percent. In the standpoint of religion, Buddhists were 42.5 percent. 2. In the number and times of respondents brushing, 35.5 percent is "after dinner", 25.6 percent is "Before going to bed", 15.8 percent is "After breakfast", 13.3 percent is "After every meal", 5.2 percent is "Before breakfast" and 4.7 percent is "The sometimes it occurs to them". 3. The acquirement process of knowledge on the dental health were clinics or health center dentists (27.6%), TV(24.5%), magazine(9.2%), school(7.8%), relatives(5.3%). and 25.6 percent has never acquired. 28.3 percent of the farmers learned something by clinics and 28.1 percent of them haven′t heard about dental health. 4. The rate of persons who experienced oral diseases during 1 year period was 76.1 percent, and that of the educated was 19.9 percent and that of the uneducated 80.1 percent. The authorities concerned with treatment were dentist′s(41.6%), health center(30.3%), and the unlicensed person(2.9%). The rate of negligence was 6.3 percent, farmers experienced oral disease was 75.2 percent and they utilized the health center most often(36.2%). 5. The rate of person who had experienced dental prosthesis during ten year period was 71.9 percent, and the final place or man for dental prosthesis was dental clinic(59.4%), the unlicensed person(27.1%), and health center(13.5%). The rate of farmers experienced dental prosthesis was 70.4 percent. They utilized the dental clinic, the unlicensed person and the health center with the rates of 51.5 percent, 32.2 percent, and 16.7 percent respectively. 6. As to the results of dental prosthesis using the dental clinic, "being satisfied now" was 72.4 percent, "being dissatisfied" 14.4 percent, "being unable to use it" 3.1 percent, "its being somewhat usable" 10.1 percent, "having some problem" 38.7 percent, and "there being no problems" 61.3 percent. About utilizing the unlicensed person, "being satisfied now" was 65.8 percent, "being dissatisfied" was 10.7 percent, "being unable to use it" 5.1 percent and "its being some what usable" was 18.4 percent. 7. The rate of missing teeth holders amounted to 89.8 percent, the rate of the educated to the uneducated was 19.2 percent to 80.8 percent The reasons of neglecting that illness were due to "Endurable"(28.3%), and "No money" (24.3%). In the case of farmers 89.1 percent of them were the missing-teeth holders, the "Endurable" were 29.8 7. percent, and "No money" lay in 27.4 percent. 8. Their hopeful centers for dental prosthesis were the dental clinics(76.6%), and the health center(16.9%).

• Journal of Korean Biological Nursing Science
• /
• v.14 no.2
• /
• pp.139-146
• /
• 2012

Purpose: This study was done to evaluate the effects of a fluid intake intervention on increasing fluid intake and ameliorating dehydration status in elders admitted to long-term care hospitals. Methods: A nonequivalent control group, pretest and posttest design was used. The experimental group of 39 participants received the 4-week intervention while the control group of 38 participants received routine care. Outcome variables were daily fluid intake and physiological indexes such as blood urea nitrogen and creatinine ratio (BUN/Cr), urine specific gravity (USG), and urine color. Results: After the intervention to increase fluid intake, there were statistically significant increases in daily fluid intake, normal BUN/Cr, and USG in the experimental group. However, a statistically significant improvement in normal urine color was not found for either group. Conclusion: The findings of this study demonstrated that the fluid intake intervention improved hydration status of the experimental group participants. Consequently, it was confirmed that the intervention is considered to be effective in preventing dehydration which occurs frequently in older adults in long-term care facilities and, thus this intervention may contribute to preventing various health issues resulting from dehydration.

• Journal of the Korean Society for information Management
• /
• v.19 no.4
• /
• pp.185-208
• /
• 2002

Information service for the aged is a new challenge for public libraries in Korea. To develop an internet-based information service at public library perspectives, information sources, information need, and information seeking and using behavior are investigated. Interview survey is performed to 1060 adults aged 60 and over. Finding revealed that the respondents led to few channels to information except for mass media and informal oral communication. It ascertain ways in which 23% of the respondents currently use internet, and identify barriers of nonusers. The information need of the elderly are diverse, but health/medicine, news, hobbies, religion, leisure/travel are most identified need in descending order. Based on data analysis and previous research results, a cooperative service model consisting of information contents, online reference, interface design, and education is developed. Finally problems and suggestions for future improvement are discussed.

• Journal of TMJ Balancing Medicine
• /
• v.11 no.1
• /
• pp.20-24
• /
• 2021

Objectives: This study was designed to report the clinical improvement of the patient with glossodynia. Methods: During the treatment period (from Jul. 7^th, 2021 to Aug. 3^rd), a patient was treated using acupuncture, Korean Medicine, pharmacopuncture and FCST (Functional Cerebrospinal Therapy). Symptoms were evaluated by Visual Analogue Scale (VAS), the Oral Health Impact Profile-14 (OHIP-14). Results: After the treatments for 28 days, the OHIP-14 score decreased from 53 to 7. Also, the patient's VAS score decreased from 6 to 0. Conclusions: Korean medicine treatment with FCST may be valuable for glossodynia patients. Nevertheless further studies are needed.

• Food Science of Animal Resources
• /
• v.44 no.1
• /
• pp.119-131
• /
• 2024

BIOVITA 3 bacterial species (BIOVITA 3), a probiotic blend powder containing Clostridium butyricum IDCC 1301, Weizmannia coagulans IDCC 1201, and Bacillus subtilis IDCC 1101, has been used as a food ingredient for gut health. However, its efficacy in improving constipation has not been reported. Therefore, we aimed to investigate the functional effects of oral administration of BIOVITA 3 as well as its component strains alone (at 1.0×10⁹ CFU/day) in Sprague-Dawley (SD) rats with loperamide-induced constipation. The study included fecal analysis, gastrointestinal transit ratio, histopathological analysis, short chain fatty acids (SCFAs), and metagenome analysis. As results, the BIOVITA 3 group showed significant improvements in fecal number, water content, gastrointestinal transit ratio, and thickening of the mucosal layer. In the SCFAs analysis, all probiotic-treated groups showed an increase in total SCFAs compared to the loperamide-constipated group. Changes in microbial abundance and the diversity index of three groups (normal, constipated, and BIOVITA 3) were also defined. Of these, the BIOVITA 3 showed a significant improvement in loperamide-constipated SD-rats. This study suggests the possibility that BIOVITA 3 can be applied as an ingredient in functional foods to relieve constipation.