• 한국치위생학회지
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• 제13권3호
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• pp.395-401
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• 2013

Objectives : The purpose of this research was to investigate the awareness of an adult on implants and the relevant factors which affect the satisfaction of a patient after an implant treatment. Methods : This study was conducted to 407 adult subjects in Seoul and Gyeonggi. A total of 384 data were analyzed except the questionnaires having poor responses or errors. Results : The acquaintance route of implant was TV advertisements, self-knowledge, internet, news, and newspapers. Dentist's ability to practice implant was the most important factor in patient's choice. The responents answered the expected lifespan of an implant was more than 5 years to 10 years. In terms of dental health management behavior on implants, the average response of the highest 4.07 points of 5 Likert scale. Generally women are more concerned with implant than men(p<0.01). The highly educated and elderly patients had tendency to receive more treatment(p<0.0001). Patients were more satisfactory after receiving regular checkups after treatment(p<0.05). The low expenses of implant satisfied the patients(p<0.05). Conclusions : As implant technology advances, the concern of patients on implants also increase. So reduction of cost can make the patients have access to the dentist and the patients' oral health must be improved through continuous dental care.

• 대한심미치과학회지
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• 제28권1호
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• pp.54-60
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• 2019

연구목적: 치과공포는 주로 과거의 부정적인 치과 치료 경험에 기인하여 치과 방문 시 중재되지 않은 불안과 두려움의 감정을 의미하며, 성인에서는 치과치료의 필요함을 인식함에도 불구하고 진료회피로 이어져 구강건강의 악화를 야기할 수 있다. 따라서 본 연구는 일부 성인을 대상으로 치과공포 및 불안 수준을 측정하고, 그와 관련된 요인 및 이에 영향을 미치는 원인에 대해 파악하고자 수행되었다. 연구방법: Kleinknecht's의 치과 공포 척도(Dental Fear Survey scale)를 이용하였고, SPSS 21 프로그램(IBM SPSS Statistics 21)을 사용하여 분석하였다. 연구결과: 치과공포도가 높을수록 "치과병원 문을 열고 들어설 때 두려움"가 가장 높게 나타났으며, "치과의자에 낮아 치료를 기다릴 때 두려움", "치과의사를 쳐다볼 때 두려움", "치과기구가 돌아가는 소리가 들릴 때 두려움", "치과 진료실에서 병원 냄새가 날 때 두려움" 순으로 나타났다. 고안: 치과의사와 치과위생사는 환자가 느끼는 공포와 두려움을 이해하여 체계적인 의료서비스를 제공할 수 있도록 치과 불안에 대한 여러가지 중재법을 모색할 수 있어야 한다.

• 대한간호학회지
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• 제29권1호
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• pp.84-96
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• 1999

This study was conducted to identity the degree of burden and social support perceived by mothers of nephrotic syndrome patients. Also, relations between burden and social support were investigated to provide basis data for their family health and nursing intervention. The study subjects were mothers of nephrotic syndrome patients whose children were hospitalized in 2 Pediatric wards of University Hospital in Seoul and 1 in Pusan from Jun. 1, 1998 to Jun. 30, 1998. Burden measurement Instrument for this study was designed by the researcher and its basis in one developed by Montgomery et al.(1985) and the reliability was .78. Also. P.R.Q. Part I, II by Brandt and Weinert(1981) was used as social support measurement instrument and the reliability .71. The data analysis was done by SPSS, t-test, ANOVA Pearson correlation. The result were as follows. 1. Burden felt by mothers shows an average value of 60.82 (Maximum 86, Standard deviation 1.244). 2. Of the mother characteristics, the score of burden was high in case of no religion and low income. Of the patient characteristics, the score burden ranked as high MCNS, doing oral therapy, injection therapy at the same time and negative perceived patients condition. 3. The mean score of support was 77.54(Maximum 96, Standard deviation 1.096). 4. The main supporters were husband (the highest), brother, sister, health speciality and the subject expressed the highest satisfaction toward supporters in chronic disease. 5. Of the patient characteristics, the higher age group and the elder group showed high support. Also, positive perceived patient's condition, high support. 6. The relationship between burden and social support is not significant. In conclusion to the above study, the researcher suggests. 1. The Qualitative research to investigate influential factors on burden of family of nephrotic syndrome patients is needed.

• 한국산학기술학회논문지
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• 제15권2호
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• pp.1010-1019
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• 2014

본 연구는 객관적인 국가차원의 국민건강영양조사 원시자료를 활용하여 만 14세에서 만 19세까지의 청소년을 추출하고 식품군별로 조사된 섭취빈도조사의 내용을 바탕으로 구강검진 조사의 항목으로 실시된 우식영구치수, 영구치우식유병자여부, 우식경험영구치수, 영구치우식경험여부등의 4가지 항목의 영향력 관계를 조사하였다. 우식영구치수, 영구치우식유병자 여부, 우식경험영구치 수, 영구치우식경험 여부등은 쌀과 배추 김치를 주식으로 하는 우리나라 식생활 문화에 가장 영향을 많이 받았고 쌀과 잡곡, 배추등의 채소와 과일류 등은 치아우식을 낮추는 영향을 주는 인자로 조사되었다. 쌀의 섭취 빈도가 많을수록 치아우식은 감소하는 것으로 나타났으며, 고기 생선 난류의 식품군에서는 멸치의 섭취 빈도가 많을 수록 치아우식은 감소하였고, 돼지고기와 소고기 등의 육류의 섭취 역시 치아우식의 발생을 감소시키는 것으로 나타났다. 특히 탄산음료와 패스트푸드 식품의 일종인 햄버거와 피자등의 섭취 빈도가 클수록 치아우식을 증가시키는 것으로 나타났다.

• Journal of Microbiology and Biotechnology
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• 제31권7호
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• pp.1011-1021
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• 2021

The root bark of Ulmus davidiana var. japonica (Japanese elm) is used in Korea and other East Asian countries as a traditional herbal remedy to treat a variety of inflammatory diseases and ailments such as edema, gastric cancer and mastitis. For this study, we investigated the lipid metabolism and anti-obesity efficacy of ethyl alcohol extract of Ulmus davidiana var. japonica root bark (UDE). First, HPLC was performed to quantify the level of (+)-catechin, the active ingredient of UDE. In the following experiments, cultured 3T3-L1 pre-adipocytes and high-fat diet (HFD)-fed murine model were studied for anti-obesity efficacy by testing the lipid metabolism effects of UDE and (+)-catechin. In the test using 3T3-L1 pre-adipocytes, treatment with UDE inhibited adipocyte differentiation and significantly reduced the production of adipogenic genes and transcription factors PPARγ, C/EBPα and SREBP-1c. HFD-fed, obese mice were administered with UDE (200 mg/kg per day) and (+)-catechin (30 mg/kg per day) by oral gavage for 4 weeks. Weight gain, epididymal and abdominal adipose tissue mass were significantly reduced, and a change in adipocyte size was observed in the UDE and (+)-catechin treatment groups compared to the untreated control group (^***p < 0.001). Significantly lower total cholesterol and triglyceride levels were detected in UDE-treated HFD mice compared to the control, revealing the efficacy of UDE. In addition, it was found that lipid accumulation in hepatocytes was also significantly reduced after administration of UDE. These results suggest that UDE has significant anti-obesity and lipid metabolism effects through inhibition of adipocyte differentiation and adipogenesis.

• 한국융합학회논문지
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• 제13권5호
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• pp.501-508
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• 2022

고혈압을 비롯한 기저질환자의 COVID-19 발생률과 사망률이 높다고 밝혀지고 있다. COVID-19 대유행 상황에서 건강관리를 위해서 손 씻기만큼 칫솔질은 매우 중요하다. 이에 본 연구의 목적은 고혈압 기저질환자의 칫솔질과 손 씻기 실천율과의 관련 요인을 파악하기 위하여 수행되었다. 지역사회건강조사 2020년 원시자료를 이용하여 만 40세 이상 고혈압 기저질환자 62,762명을 대상으로 분석하였다. 연구결과 여성, 연령이 낮을수록, 교육수준이 높을수록, 외출 시 마스크 착용자, 점심식사 후 칫솔질 실천자에서 손 씻기 실천율이 높게 나타났다. 칫솔질을 실천한 고혈압 기저질환자에서 손 씻기 실천율이 더 높은 것으로 나타나 구강위생과 개인방역 사이의 연관성을 확인하였다. COVID-19 감염에 취약한 기저질환자에게 감염병 예방 행태 실천율을 높이기 위한 지속가능한 방안 마련이 필요할 것으로 사료된다.

• Anatomy and Cell Biology
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• 제56권4호
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• pp.552-561
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• 2023

The endocrinology of type 2 diabetes (T2D) and its predisposing factors have been studied extensively while its skeletal effects have received negligible research despite this being a global disease. The cellular and molecular association between proximal humeral fractures and T2D has not been fully elucidated. We aimed to study bone cell quantities and immunolabel osteogenic and antiosteogenic cytokines. The study used 12-week-old rats (23 males) consisting of 8 Sprague Dawley (SD) and 15 Zucker Diabetic Sprague Dawley (ZDSD). Weekly mass measurements were taken while fasting blood glucose levels were recorded every 2 weeks with oral glucose tolerance tests conducted once every 4 weeks. Upon termination at the age of 28 weeks, humeri were fixed in 10% buffered formalin, prior to decalcification in ethylenediaminetetraacetic acid. The bone samples were then processed in ascending grades of alcohol using an automatic processor before embedding in paraffin wax. Sections were cut at 5 ㎛ thickness in a series for Haematoxylin and Eosin stain, and immunohistochemistry was performed with the anti-tartrate-resistant acid phosphatase (TRAP), anti-alkaline phosphatase (ALP), anti-bone morphogenetic protein 3 (BMP3), anti-transforming growth factor beta 1 (TGFβ1), anti-aged glycation end product (AGE) antibodies in the sequence. ZDSD rats had more adipocytes, BMP3 and AGEs expression with higher numbers of TRAP positive osteocytes and fewer ALP cells although no differences were found in TGFβ1 immunopositivity. We also found that T2D increases the number of AGEs immuno-positive cells, as well as its extracellular expression, thus providing a conducive environment for the interaction of the osteogenic cytokine and its antagonist to suppress osteoblastogenesis. ZDSD groups had higher adipocyte numbers therefore increased marrow adiposity in T2D.

• Journal of Nutrition and Health
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• 제30권3호
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• pp.307-317
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• 1997

To determine the effects of endogenous and exogenous strogen on serum lipid levels, twenty nonsmoking healthy Korean women were participated in this experiment for 12 weeks. They were assigned to three groups : (1) eight women aged 22 to 30(yr) for the premenopausal(Pre) group, (2) eight, aged 49 to 60(yr) for the postmenoparusal(Pst) group, (3) four, aged 23 to 30(yr) for the oral contraceptive(OC) group which used triphasic OC formulation. Fasting blood samples representing every phase of the hormonal levels were obtained from the subjects of the Pre and the OC group. From the subjects of the Pst group, fasting blood samples were obtained once per three weeks for 12 weeks. All the serum data were adjusted for dietary effects, exercise, personality type and body mass index(BMI) by using analysis of covariation(ANCOVA). Serum lipid levels of the three groups were significantly different. While serum levels of triglycerides(TG)(p<0.0001), low density lipoprotein-chloesterol(LDL-C)/high density liporotein-cholesterol(HDL-C) ratio (LDC-C/HDL-C)(P<0.01) and total cholesterol (TC)/HDL-C ratio (TC/HDL-C)(P<0.001) were significatnly high in the Pst group, serum HDL-C(P0.001) level was significantly high in the Pre group. The OC group showed significantly low serum TC(P<0.0001) and LDL-C(P<0.0001) levels. There was no signidicant difference in the fluictuation of serum lipid levels during the menstrual cycle of the Pre group. However, in the OC group, serum TG level was significantly increased at phase 2(P<0.05) where exogenous estrogen administration was highest. Even though other serum lipid levels of the OC group were not significantly fluctuated according to the exogenous estrogen administration, there was a trend of increased levels of serum TC, LDL-C, LDL-C/HDL-C and TC/HDL-C and decreased level of HDL-C during the menstruation period. Also, serum TC level was high(P<0.005) and serum TG level was low (P<0.005) at the baseline of the OC group compared with the periods of OC administration. When screening and counseling the female population at risk for coronary heart disease(CHD), the result of this study suggest that in may be desirable to divide the population into several groups according to their personal physiological characteristics, such as age, OC administration, menstrual cycle and menopause, as well as general risk factors for CHD.

• 치위생과학회지
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• 제11권4호
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• pp.367-373
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• 2011

본 연구는 중 고등학생들의 치과치료공포감 및 치과의사불신감에 따른 치아우식경험도를 파악하고 이에 영향을 미치는 요인들을 조사하기 위하여 2009년 7월 1일 부터 9월 30일까지 임의 선정된 대구광역시 소재 6개 중학교 1, 2, 3학년과 2개 고등학교 1학년 총 750부를 자기기입식 설문조사를 시행 한 후 성실하게 답변 하지 못한 30부의 설문지를 제외한 최종 720부와 치아우식경험실태조사 자료를 분석하여 다음과 같은 결과를 얻었다. 1. 치과치료공포감의 요인 중 자극반응이 3.42점으로 가장 높은 점수를 보였고, 치과의사불신감은 치과의사에 대한 환자 불신 요인이 3.07점의 평균점수를 보였다. 2. 인구사회학적 특성 중 여학생이 남학생보다 치과치료공포감과 치과의사불신감이 높게 나타났고, 중학생의 경우 연령이 증가할수록 치과치료에 대한 공포감이 높게 나타났다. 3. 치과치료공포수준이 높을수록(p<0.01), 치과의사불신감(p<0.05)이 높을수록 우식경험영구치지수가 높게 나타났으며, 통계적으로 유의미한 차이가 있었다. 4. 치과의사불신감($\beta$=0.393)이 높을수록 치과치료공포감이 높게 나타났으며, 통계적으로 유의한 정적관계가 있는 것으로 밝혀졌다. 이상의 결과를 미루어 볼 때 치과진료회피 현상을 감소시키기 위하여 환자 맞춤형 의료서비스를 제공한다면 치과치료에 대한 공포감 및 치과의사불신감을 줄이고 치아우식증 발생률이 감소함으로써 청소년들의 구강건강향상에 큰 도움이 될 것이다.

• 대한장애인치과학회지
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• 제7권1호
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• pp.33-37
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• 2011

제1대구치의 이소맹출은 국소적 원인과 유전적 원인의 조합에 의한 다양한 요소에 의해서 유발된다. 주기적인 검진과 방사선학적 검사를 통해 비가역적 이소맹출로 판단 될 경우, 제2유구치 조기 상실에 의해 제1대구치의 근심경사나 회전 및 복잡한 교정적인 문제를 일으킬 수 있으므로 적절한 개입이 필요하다. 본 증례는 항암치료의 기왕력이 있는 만성 골수성 백혈병 환아에서 나타난 제1대구치의 이소맹출을 Halterman appliance를 이용하여 정상적인 맹출로 유도할 수 있었다.