• 치위생과학회지
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• 제19권2호
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• pp.86-95
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• 2019

The modern era of microbial genome analysis began in earnest in the 2000s with the generalization of metagenomics and gene sequencing techniques. Studying complex microbial community such as oral cavity and colon by a pure culture is considerably ineffective in terms of cost and time. Therefore, various techniques for genomic analysis have been developed to overcome the limitation of the culture method and to explore microbial communities existing in the natural environment at the gene level. Among these, DNA fingerprinting analysis and microarray chip have been used extensively; however, the most recent method of analysis is metagenomics. The study summarily examined the overview of metagenomics analysis techniques, as well as domestic and foreign studies on disease genomics and cluster analysis related to oral metagenome. The composition of oral bacteria also varies across different individuals, and it would become possible to analyze what change occurs in the human body depending on the activity of bacteria living in the oral cavity and what causality it has with diseases. Identification, isolation, metabolism, and presence of functional genes of microorganisms are being identified for correlation analysis based on oral microbial genome sequencing. For precise diagnosis and treatment of diseases based on microbiome, greater effort is needed for finding not only the causative microorganisms, but also indicators at gene level. Up to now, oral microbial studies have mostly involved metagenomics, but if metatranscriptomic, metaproteomic, and metabolomic approaches can be taken together for assessment of microbial genes and proteins that are expressed under specific conditions, then doing so can be more helpful for gaining comprehensive understanding.

• Journal of Oral Medicine and Pain
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• 제33권1호
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• pp.27-33
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• 2008

구강 캔디다증은 주요 기회감염 균주인 Candida 속(屬) 진균류에 의한 감염성 질환으로 구강점막에 발생하는 진균 감염 중 가장 흔하지만, 만성증식성(chronic hyperplastic type)이나 정중능형설염(median rhomboid glossitis)과 같이 드문 형태의 경우 오진의 가능성이 있고 효과적인 치료법의 결정도 어려운 경우가 있다. 본 증례에서는 만성증식성 구강 캔디다증 및 정중능형설염으로 진단된 환자에서 nystatin 처방에 효과적으로 반응하지 않아 fluconazole을 투여하여 증상의 경감과 치유를 보인 예를 보고하고자 한다.

• 한국치위생학회지
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• 제12권3호
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• pp.471-483
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• 2012

Objectives : This study looked at the relationship between occupational stress and the Oral Health Impact Profile (OHIP), to evaluate the effect of occupational stress-related factors. Methods : Data was obtained from a cross-sectional survey of 260 local officials in Gangwondo. The research comprised three questions relating to subjective oral symptoms, an occupational stress measurement tool and an oral health impact factor which was composed of questions. The data was analysed using t-test, one-way ANOVA, Pearson correlation and path analysis in Amos. Results : Occupational stress had a positive correlation to drinking frequency, Oral symptoms had a negative correlation. And drinking frequency, smoking amount and occupational stress had a positive correlation to oral symptoms. It denoted that drinking frequency, occupational stress and oral symptoms had a negative correlation to OHIP. The path model had an excellent goodness of fit (p=0.07, namely p>0.05). Five 'goodness-of-fit indices' of the model were all above 0.9: GFI=0.987, AGFI=0.952, NFI=0.902, IFI=0.939, CFI=0.934), and its RMSEA was 0.045. Occupational stress and oral symptoms had a firsthand impact on OHIP. In addition, it affected OHIP through the parameters of oral symptoms. Occupational stress exercised a firsthand influence on drinking frequency, drinking frequency exercised a firsthand influence on smoking amount. Smoking amount had a firsthand impact on oral symptoms. Conclusions: Oral health education programs for the development of an improved oral hygiene environment through reduction in drinking and smoking also need to focus on relieving stress by improving workplace culture. In addition, due to good communication is required to reduce occupational stress caused by interpersonal conflict.

• 한국치위생학회지
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• 제13권6호
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• pp.1005-1014
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• 2013

Objectives : The purpose of the study is to obtain the basic data for an industrial oral health project enhancing the quality of life and oral health. Methods : Questionnaire consisted of 17 questions including 7 questions of general characteristics, 5 questions of oral health awareness, and 5 questions of the behavior of oral health. A self-reported questionnaire was carried out from September 1 to September 28, 2012, The subjects were 400 male and female sanitation workers in private corporations in Jeonju. A total of 354 questionnaires were analyzed using SPSS windows ver. 12.0 (SPSS Inc. Korea). Results : The majority of the subjects were male in 50's. Temporary contract workers are older aged and 2 to 5 years of career workers were the majority of the cleaners. Average monthly income was less than 2 million Korean Won. Those who had a higher academic background and permanent position tended to have oral health knowledge (p<0.05). Female workers had healthier subjective oral health status than male workers. Those who were in older age, single, temporary position, and 2 to 5 years of career tended to have healthier subjective oral health status (p<0.05). Those who were in older age, married, and long period of employment were worrying about their health (p<0.05). The subjective oral health knowledge was high in 49.7% of the workers because they were not able to brush teeth during work hours. They were able to brush their teeth only after dinner. It was low in female and older aged workers (p<0.05). The brushing method included a combination of top to bottom and from the side to side. Conclusions : This study showed the influencing factor of oral health in street workers. Work environment, education, age, monthly income, and types of employment were the important factors to oral health care. It is necessary to provide the right oral health care program for the workers in the near future.

• 대한치위생과학회지
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• 제3권2호
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• pp.51-58
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• 2020

Oral examination ensures early detection and treatment of oral diseases and improvement of quality of health-related life. This is imperative as it reduces individuals' dental medical expenses and social costs caused by diseases. However, as the low oral examination acceptance rate continues to be a problem, this study was conducted to identify the factors that influence the oral examination of an economically active population. In this study, 4,836 economically active individuals between the ages of 20 and 65 years were studied using data from the 7th National Health and Nutrition Survey in 2018. Logistic regression analysis was performed to determine the factors influencing demographic and sociological characteristics on oral examination after adjusting for complaints of mastication and speech discomfort. As a result of confirming the factors influencing the oral examination, increase in age tended to be inversely proportional to the oral examination. Income level, type of job, and job position were identified as factors that influenced oral examinations. Compared to the group with a high socioeconomic status, which is represented by a group with a high income level or a stable job type or job position, the group with low economic status was found to have a negative effect on oral examination. Oral management of vulnerable groups, who might not be considered while devising oral health management policies, should be promoted through the development and provision of oral health management policies that consider employment status and environment.

• Journal of Oral Medicine and Pain
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• 제20권1호
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• pp.7-18
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• 1995

The Purpose of this article is to describe the biochemical properties and biological functions of several salivary proteins that possess the unusual properties of inhibiting spontaneous and secondary precipitation of calcium phosphate. This function is very important since human salivary secretion is supersaturated with respect to calcium phosphate. Biological function of statherin, proline rich protein (PRP) and histidine rich protein (HRP) is to inhibit precipitation of calcium phosphate in salivary glands, in the oral fluids, and onto tooth surfaces. The resulting supersaturated state of the salivary secretions contributes a protective and reparative environment which is important for the integrity of the tooth. Beneficial consequences of salivary supersaturation with respect to calcium phosphate are selectively expressed in the oral cavity- that is, protection is provided for the dental enamel-while undesirable consequences, for example, precipitation of calcium phosphates in the salivary glands and onto the teeth do not occur. Purification and structural characteristics of these proteins as well as clinical significance of functions of each protein will be discussed.

• 대한치과마취과학회지
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• 제14권4호
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• pp.233-236
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• 2014

In order to reduce jaw fracture accompanied by basal skull or nasal fracture, submental intubation could be generally performed. Albeit submental intubation has been widely accepted, it could develop complications such as nerve injury, glandular duct injury, and orocutaneous fistula. Here, we suggest oral intubation for overcoming complications and providing more stable surgical environment in emergency case. Under oral intubation maintaining in retromolar triangle and buccal corridor space, intermaxillary fixation was successfully underwent in 38-years-old female patient with Le Fort I fracture accompanied by pneumocephalus.

• 한국치위생학회지
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• 제19권2호
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• pp.161-172
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• 2019

Objectives: This study aimed to analyze the correlation between oral function, oral environment, and brain cognitive function in the elderly. Methods: The subjects were 60 users of senior community center and elderly day care center. The survey was conducted from November to December 2018. Subjects were assessed by oral examination and myofunction test. Oral myofunction was measured using $IOPI^R$ and Lip de $Cum^R$. Survey data were analyzed using the statistical programs of PASW Statistics ver. 18.0. Results: Tongue muscle strength and lips muscle strength was higher in males than in females. The tongue and lip strengths were higher in the <81 years old group than the ${\geq}81$ years old group. Functional tooth analysis showed that there was a ${\geq}15$ teeth group ($40.91{\pm}7.36$) and a <15 teeth group ($32.52{\pm}7.14$). Lip muscle strength analysis showed that the ${\geq}15$ teeth group ($10.54{\pm}3.40$) was higher than the <15 teeth group ($8.20{\pm}2.41$, p<0.05). Tongue muscle strength, lumbar muscle strength, and functional tooth number were lower in the elderly subjects with mild cognitive impairment. Cognitive function was significantly correlated with functional tooth number (r=0.386, p<0.001), tongue strength (r=0.478, p<0.001), and lip strength (r=0.281, p<0.05). Tongue strength was significantly correlated with lip strength (r=0.360, p<0.001) and functional tooth number (r=0.633, p<0.001). Lip strength was significantly correlated with functional tooth number (r=0.376, p<0.001). Conclusions: These results showed that age and functional tooth number influenced oral muscle strength and that the number of functional teeth and oral muscle strength were low in the elderly with mild cognitive impairment. Oral myofunction training and oral care program are suggested to improve the quality of life of the elderly.

• International Journal of Oral Biology
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• 제41권2호
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• pp.75-81
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• 2016

Human mouth environment is known to include a variety bacteria, including Streptococcus spp., Staphylococcus spp., Actinomyces spp., Lactobacillus spp., Candida spp., Enterobacteriaceae, et al. Human oral microorganisms can cause dental caries, gingivitis, periodontitis, respiratory tract infection, and cardiovascular disease. Thus, right denture cleaning is essential to oral and general human health. The aim of this study was to evaluate the bactericidal effect of a sodium dichloroisocyanurate-based effervescent tablet (Aos Denti Germ, Aos Company, Chungbuk, Korea) against oral microorganisms. A total of 5 species Streptococcus spp. (Streptococcus anginosus, Streptococcus mitis, Streptococcus mutans, Streptococcus oralis, and Streptococcus sobrinus), Actinomyces oris, Candida albicans, and Escherichia coli were used in this study. All strains were exposed to the distilled water prepared with effervescent tablet. After the exposure, the mixture of strains and effervescent tablet was inoculated onto blood agar or MacConkey agar plate and cultured at $36^{\circ}C$. All strains were killed immediately on exposure to effervescent tablet. The results suggested that effervescent tablet could be used as an effective denture cleanser for dental hygiene.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제42권1호
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• pp.38-42
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• 2016

The purpose of this study is to evaluate the degree of osseointegration of resorbable blasting media (RBM) surface implants retrieved from humans. Three implants in the mandibular molar region that were surface-treated with RBM were retrieved from two patients. The implants were used to manufacture specimens in order to measure the bone-implant contact (BIC) ratio. The BIC ratios of the three implants were found to be an average of $69.0%{\pm}9.1%$. In conclusion, that RBM surface implants are integrated into the host environment with histological significance and the BIC ratio of the RBM surface-treated implant was not significantly different from that of other surface-treated implants.