• Journal of Oral Medicine and Pain
• /
• v.48 no.4
• /
• pp.174-180
• /
• 2023

Pemphigus vulgaris (PV) is a chronic autoimmune bullous disease caused by autoantibodies to proteins in the oral mucosa and skin. It is a rare disease with an annual incidence of 2.059 per million in South Korea. In many patients with PV, oral mucosal lesions precede other lesions elsewhere, and oral lesions can be the only manifestation. Early diagnosis is important because the disease has a high mortality rate if untreated appropriately in the early stages, and rapid treatment initiation is associated with rapid disease control. Oral PV lesions are clinically variable. In this study, we describe oral PV lesions in a 60-year-old woman, a 75-year-old man, and a 60-year-old man presenting with various clinical presentations. Oral PV lesions can affect any part of the oral mucosa, including the buccal mucosa, gingiva, tongue, palate, and free mucosa, and can vary in appearance from desquamative gingivitis, painful ulcers, and erosions to aphthous-like stomatitis. Clinicians should be aware of the difficulty of early diagnosis in PV, particularly when oral lesions are the only manifestation, and should consider many factors, including the patient's age, to make an accurate diagnosis and manage oral lesions to improve the patient's quality of life and avoid delayed diagnosis.

• Journal of Korean society of Dental Hygiene
• /
• v.20 no.5
• /
• pp.603-610
• /
• 2020

Objectives: This study was aimed at investigating the oral hygiene device use by cardiovascular disease patients and assessing related factors. Methods: We used data of 1,630 cardiovascular disease patients (including hypertension, stroke, and myocardial infarction) from the 7th Korean National Health and Nutrition Examination Survey (2016-2018). The χ² test and logistic regression analysis were performed to analyze the oral hygiene device use by the subjects and assess related factors. All statistical analyses were performed with the IBM SPSS Statistics, version 20.0. Results: The oral hygiene device use and related factors were significantly higher in patients with an educational level of middle school or below high school, with a score of 1.85 (95% confidence interval [CI] = 1.35-2.53), or college, with a score of 1.93 (95% CI = 1.19-3.14), compared to those with an educational level below primary school. Further, the oral hygiene device use and related factors were significantly higher in patients who answered 'yes', with a score of 1.96 (95% CI = 1.42-2.73), compared to those who answered 'no' to the question on oral examination. Conclusions: More patients with cardiovascular disease did not use oral hygiene devices than those who did. It is necessary to expand the approach of preventive treatment to increase the utilization rate of oral hygiene devices.

• Imaging Science in Dentistry
• /
• v.50 no.3
• /
• pp.255-260
• /
• 2020

Acquired facial lipoatrophy is a rare disease with an unclear etiology and pathological pathway. The distinct causative factors of this disease have been not elucidated, but it is suspected to be associated with immune system-related diseases, most notably AIDS. Although the management of facial lipoatrophy is very important for patients' social life and mental health, no treatment framework has been developed due to the unknown nature of the disease manifestation. The present case report was designed to provide sequential imaging to visualize the disease progression. The clinical backgrounds of the patients are also introduced, helping characterize this disease entity more clearly for maxillofacial specialists.

• 한국약용작물학회:학술대회논문집
• /
• 2009.05a
• /
• pp.297-298
• /
• 2009

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• v.26 no.2
• /
• pp.219-223
• /
• 2000

Behcet's disease is a chronic, multisystemic disorder which is more frequently seen in the Mediterranean basin, Middle East, and Far East. The mean age at the first onset is third decades. In large series of patients, men predominate over women. Infectious agents, immune mechanisms, and genetic factors are implicated in the etiopathogenesis of the disease. Eyes, skin, joints, the oral cavity, blood vessels, and central nervous system are usually involved, although less frequently the heart, lung, kidney may be affected. The prognosis of the disease has been improved because of early diagnosis and suitable treatment. Local remedies and systemic administration of colchicine, corticosteoids, immunosuppressives, and other agents have been applied. Pathergy, or skin hypersensitivity to needle puncture has been reported as a diagnostic test for Behcet's disease. We have managed a Behcet's disease patient with pathergy test & corticosteroids therapy. We have obtained good result and report this case with review of literatures.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• v.48 no.2
• /
• pp.117-121
• /
• 2022

Infantile osteomyelitis is a rare disease that is infective in nature and may rapidly turn fatal, as the disease is often misdiagnosed due to its varied presenting signs. Early diagnosis may help in avoiding systemic involvement and permanent deformity. The disease presents with signs of orbital involvement, nasal congestion, and emesis, as well as other standard hallmarks of infection. Furthermore, the maxilla is a highly vascular and porous bone and the occurrence of osteomyelitis in an infant maxilla is highly uncommon. In addition, routine blood work is not suggestive of the presence of this disease. Thus, prompt diagnosis of this condition poses a challenge to surgeons due to the confusing array of symptoms combined with the rarity of the disease. One such case of osteomyelitis of the maxilla in a young child is presented. The dilemma encountered by the surgeon during the diagnosis and treatment of the disease is discussed.

• Journal of Korean Academy of Dental Administration
• /
• v.6 no.1
• /
• pp.1-10
• /
• 2018

Prior to the end of the 20th century, microorganism research was limited to culture and has since been revolutionized by genetic analysis. Microorganisms, including bacteria, can cause disease, but most of them are commensal microorganisms in our bodies. This knowledge changes the pathological approach to infectious diseases and lends to a new perspective on the effects of gut and oral microorganisms on disease and health. The oral cavity, particularly the periodontal pocket, is considered to be a reservoir of microbes that cause disease, and oral microbial control is becoming more important. In this review, I will examine the changes in the microbiological revolution and the meaning of oral healthcare management based on those changes.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.20
• /
• pp.8887-8891
• /
• 2014

Oral squamous cell carcinoma (OSCC) is predominantly a disease of middle-aged men with long-term exposure to tobacco and alcohol. An increasing trend has been reported at a younger age worldwide. Clinical records of 100 patients under the age of 45 years treated specifically for oral cavity SCC in our hospital during a 10-year period were retrospectively analyzed to calculate the survival rates. An obvious male predominance coincided with smoking trend among Chinese young individuals and female patients were more likely to have no traditional risk factors such as smoking or drinking. The 5-year overall survival rate and disease-free survival rate were 61.0% and 75.5%, respectively, consistent with other published series over the decade showing a relatively better survival among the young. No significant differences clearly correlated with outcome when comparing non-smokers non-drinkers to ever-smokers and ever drinkers (P>0.05). Overall survival rate and disease free survival rate was found to be significantly higher in patients with early-stage disease than with advanced stage disease (P=0.001, P=0.009 respectively). The strong influence of clinical stage on prognosis emphasizes the importance of early diagnosis and treatment of oral malignancies for this unique clinical subgroup.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• v.33 no.5
• /
• pp.554-558
• /
• 2007

Kimura's disease is a chronic inflammatory disorder presenting regional lymphadenopathy with painless soft tissue mass. Clinically, peripheral eosinophilia and elevated serum IgE levels are observed, and proteinuria associated with renal disease can also be present. Although its etiology is not clearly understood, it occurs predominantly in young Asian males and presents as a deep, subcutaneous mass involving salivary glands of the preauricular and submandibular regions. Spontaneous remission is very rare, and although treatments such as steroid, cytotoxic therapy and irradiation are available, chronic recurrence is very common. As such, surgical excision is regarded as the mainstay of therapy for localized lesions. Histopathologically, Kimura's disease features eosinophilic abscsesses and dense lymphoid aggregates with germinal center. Clinical differential diagnosis of Kimura's disease from other parotid diseases with accompanying lymphadenopathy is often very challenging prior to biopsy. The authors report a case of a 19-year-old male diagnosed with Kimura's disease in the parotid region who underwent surgical excision and was followed up for 6 years, along with a review of related literature.

• Journal of Korean society of Dental Hygiene
• /
• v.19 no.4
• /
• pp.555-564
• /
• 2019

Objectives: The purpose of this study was to investigate how mental health status affects oral health in the elderly. Methods: The subjects of the study provided the data for the sixth Korea National Health and Nutrition Examination Survey from 2013 to 2015. Four-hundred and twenty-one subjects were selected for the study. All data were analyzed by complex sampling frequency, chi-square test, and composite multiple regression analysis using SPSS 21.0 version. In addition, a significance level of 0.05 was considered. Results: The general factors affecting cases of periodontal disease were general characteristics, mental health status, oral health status, elderly males, household income, education level, daily brushing frequency, speaking, and stress. The effect of periodontal disease was 1.64 times higher in the male group than in the female group (p<0.001). In the household income level, the 'low' group had 1.91 times more periodontal disease, while the 'mid low' group had 1.64 times more periodontal disease than the 'high' group (p<0.05). Periodontal disease was found to be lower in the group that recognized subjective oral health status as 'good' (p<0.05). The study subjects had low levels of periodontal disease when there was no speaking difficulty (p<0.05). Conclusions: Therefore, in order to improve oral health of the elderly, it is necessary to understand the mental health condition of the elderly and prepare proper oral health education programs accordingly. Institutional devices for various oral health projects should be prepared, as well.